| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chiaki Fukuhara, James C Dirden, Gianluca Tosin. Analysis of gene expression following norepinephrine stimulation in the rat pineal gland using DNA microarray technique. Journal of pineal research. vol 35. issue 3. 2004-05-12. PMID:12932204. |
several studies have demonstrated that norepinephrine (ne) is the critical neurotransmitter for the regulation of gene expression in the pineal gland. |
2004-05-12 |
2023-08-12 |
rat |
| M Frances Davies, Janet Tsui, Judy A Flannery, Xiangqi Li, Timothy M DeLorey, Brian B Hoffma. Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 2. 2004-04-27. PMID:14583739. |
considering the importance of the neurotransmitter norepinephrine in forming memories for fearful events, we have investigated the acute and chronic effects of dexmedetomidine on discrete cue and contextual fear conditioning in mice. |
2004-04-27 |
2023-08-12 |
mouse |
| Anne M Etge. Ovarian steroid and growth factor regulation of female reproductive function involves modification of hypothalamic alpha 1-adrenoceptor signaling. Annals of the New York Academy of Sciences. vol 1007. 2004-03-25. PMID:14993049. |
the alpha(1)-adrenoceptors are thought to mediate the facilitatory effects of the catecholamine neurotransmitter norepinephrine on both lordosis behavior and lh release. |
2004-03-25 |
2023-08-12 |
Not clear |
| M F Piacentini, R Clinckers, R Meeusen, S Sarre, G Ebinger, Y Michott. Effect of bupropion on hippocampal neurotransmitters and on peripheral hormonal concentrations in the rat. Journal of applied physiology (Bethesda, Md. : 1985). vol 95. issue 2. 2004-03-19. PMID:12692144. |
the purpose of the present study was to administer an acute dose of the dual dopamine norepinephrine reuptake blocker bupropion in freely moving rats and to monitor the extracellular neurotransmitter concentrations in the hippocampus via in vivo microdialysis and the peripheral hormonal concentrations via catheterization. |
2004-03-19 |
2023-08-12 |
rat |
| Maurizio Fav. The role of the serotonergic and noradrenergic neurotransmitter systems in the treatment of psychological and physical symptoms of depression. The Journal of clinical psychiatry. vol 64 Suppl 13. 2004-01-20. PMID:14552653. |
although the pathophysiology of depression is still unknown, there is significant evidence for abnormalities of the norepinephrine (ne) and serotonin (5-ht) neurotransmitter systems in depressive disorders. |
2004-01-20 |
2023-08-12 |
Not clear |
| Filippo S Giorgi, Michela Ferrucci, Gloria Lazzeri, Chiara Pizzanelli, Paola Lenzi, Maria G Alessandrl, Luigi Murri, Francesco Forna. A damage to locus coeruleus neurons converts sporadic seizures into self-sustaining limbic status epilepticus. The European journal of neuroscience. vol 17. issue 12. 2003-09-24. PMID:12823466. |
various studies demonstrated that the neurotransmitter norepinephrine (ne) plays a relevant role in modulating seizures; in particular, a powerful effect consists in delaying the kindling of limbic areas such as the amygdala and hippocampus. |
2003-09-24 |
2023-08-12 |
rat |
| Dene Simpson, Caroline M Perr. Atomoxetine. Paediatric drugs. vol 5. issue 6. 2003-09-16. PMID:12765489. |
in vitro, ex vivo and in vivo studies have shown that atomoxetine is a highly selective antagonist of the presynaptic norepinephrine transporter with little or no affinity for other noradrenergic receptors or other neurotransmitter transporters or receptors. |
2003-09-16 |
2023-08-12 |
Not clear |
| Ian D Hentall, Riza Mesigil, Alberto Pinzon, Brian R Nog. Temporal and spatial profiles of pontine-evoked monoamine release in the rat's spinal cord. Journal of neurophysiology. vol 89. issue 6. 2003-08-01. PMID:12612020. |
in the spinal cord, the monoamine neurotransmitter norepinephrine, which is released mainly from fibers descending from the dorsal pons, has major modulatory effects on nociception and locomotor rhythms. |
2003-08-01 |
2023-08-12 |
rat |
| L Sawaki, K J Werhahn, R Barco, L Kopylev, L G Cohe. Effect of an alpha(1)-adrenergic blocker on plasticity elicited by motor training. Experimental brain research. vol 148. issue 4. 2003-04-28. PMID:12582834. |
recovery of motor function elicited by motor training after cortical lesions in rats is enhanced by norepinephrine (neurotransmitter mediating alpha(1)-adrenergic function) and downregulated by alpha(1)-adrenergic antagonists. |
2003-04-28 |
2023-08-12 |
rat |
| M K Hahn, R D Blakel. Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders. The pharmacogenomics journal. vol 2. issue 4. 2003-02-10. PMID:12196911. |
the norepinephrine, dopamine and serotonin transporters (net, dat and sert, respectively), limit cellular signaling by recapturing released neurotransmitter, and serve as targets for antidepressants and drugs of abuse, emphasizing the integral role these molecules play in neurotransmission and pathology. |
2003-02-10 |
2023-08-12 |
human |
| Bruce R Stevens, Daniel H Feldman, Zhilin Liu, William R Harve. Conserved tyrosine-147 plays a critical role in the ligand-gated current of the epithelial cation/amino acid transporter/channel CAATCH1. The Journal of experimental biology. vol 205. issue Pt 16. 2003-02-07. PMID:12124378. |
this tyrosine residue is conserved within the third transmembrane domain in members of the na(+):neurotransmitter transporter family (snf), where it plays a role in binding pharmacological ligands such as cocaine to the serotonin (sert), dopamine (dat) and norepinephrine (net) transporters. |
2003-02-07 |
2023-08-12 |
xenopus_laevis |
| Thomas Spencer, John H Heiligenstein, Joseph Biederman, Douglas E Faries, Christopher J Kratochvil, C Keith Conners, William Z Potte. Results from 2 proof-of-concept, placebo-controlled studies of atomoxetine in children with attention-deficit/hyperactivity disorder. The Journal of clinical psychiatry. vol 63. issue 12. 2003-02-05. PMID:12523874. |
atomoxetine is a highly specific inhibitor of the presynaptic norepinephrine transporter with minimal affinity for other noradrenergic receptors or other neurotransmitter transporters or receptors. |
2003-02-05 |
2023-08-12 |
Not clear |
| Simi Vincent, David Robertso. The broader view: catecholamine abnormalities. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 12 Suppl 1. 2002-12-20. PMID:12102462. |
norepinephrine (ne), a vital neurotransmitter in both the central and peripheral nervous systems, is synthesized by dopamine beta-hydroxylase (dbh) through the oxidation of dopamine (da) to ne. |
2002-12-20 |
2023-08-12 |
Not clear |
| Joseph Biederman, John H Heiligenstein, Douglas E Faries, Nora Galil, Ralf Dittmann, Graham J Emslie, Christopher J Kratochvil, Harry F Laws, Kory J Schu. Efficacy of atomoxetine versus placebo in school-age girls with attention-deficit/hyperactivity disorder. Pediatrics. vol 110. issue 6. 2002-12-11. PMID:12456942. |
atomoxetine is a potent inhibitor of the presynaptic norepinephrine transporter with minimal affinity for other noradrenergic receptors or for other neurotransmitter transporters or receptors. |
2002-12-11 |
2023-08-12 |
Not clear |
| T M McLeod, A L López-Figueroa, M O López-Figuero. Nitric oxide, stress, and depression. Psychopharmacology bulletin. vol 35. issue 1. 2002-11-26. PMID:12397868. |
while the role of neurotransmitters such as serotonin, norepinephrine (ne), dopamine (da), corticotropin-releasing hormone (crh), and arginine vasopressin (avp) has been extensively studied, new evidence suggests a role for the unique neurotransmitter nitric oxide (no). |
2002-11-26 |
2023-08-12 |
Not clear |
| David S Goldstein, David Robertson, Murray Esler, Stephen E Straus, Graeme Eisenhofe. Dysautonomias: clinical disorders of the autonomic nervous system. Annals of internal medicine. vol 137. issue 9. 2002-11-22. PMID:12416949. |
chronic orthostatic intolerance associated with postural tachycardia can arise from cardiac sympathetic activation after "patchy" autonomic impairment or blood volume depletion or, as highlighted in this discussion, from a primary abnormality that augments delivery of the sympathetic neurotransmitter norepinephrine to its receptors in the heart. |
2002-11-22 |
2023-08-12 |
human |
| Sanjeev Choudhary, Geetu Raheja, Vandana Gupta, Kiran Dip Gil. Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB). vol 6. issue 1. 2002-10-09. PMID:12186780. |
single subcutaneous dose of dichlorvos (200 mg/kg body weight) resulted in marked changes in the dopaminergic neurotransmitter system in terms of increased levels of both dopamine and norepinephrine along with significant increase in the activity of both the catecholamine synthesizing enzymes, tyrosine hydroxylase (th) and dopamine-beta-hydroxylase. |
2002-10-09 |
2023-08-12 |
rat |
| Bogdan Lewczu. Presynaptic autoregulation of norepinephrine release from the sympathetic nerve fibers in the pineal gland of the domestic pig. Pharmacological characterization of alpha(2)adrenoceptors mediating this process. Neuro endocrinology letters. vol 23 Suppl 1. 2002-09-24. PMID:12019363. |
norepinephrine is the main neurotransmitter controlling melatonin secretion in the mammalian pineal gland. |
2002-09-24 |
2023-08-12 |
Not clear |
| Dennis K Miller, Sangeetha P Sumithran, Linda P Dwoski. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183670. |
the present study evaluated bupropion-induced inhibition of native alpha3beta2* and alpha3beta4* nachrs using functional neurotransmitter release assays, nicotine-evoked [(3)h]overflow from superfused rat striatal slices preloaded with [(3)h]dopamine ([(3)h]da), and nicotine-evoked [(3)h]overflow from hippocampal slices preloaded with [(3)h]norepinephrine ([(3)h]ne). |
2002-09-18 |
2023-08-12 |
rat |
| F M Leslie, K A Gallardo, M K Par. Nicotinic acetylcholine receptor-mediated release of [3H]norepinephrine from developing and adult rat hippocampus: direct and indirect mechanisms. Neuropharmacology. vol 42. issue 5. 2002-09-10. PMID:11985823. |
using in vitro neurotransmitter release, we have examined mechanisms underlying nicotine-induced [(3)h]norepinephrine release from developing and adult rat hippocampus. |
2002-09-10 |
2023-08-12 |
rat |