Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Rita Bardoni, Alessia Ghirri, Chiara Salio, Massimiliano Prandini, Adalberto Merigh. BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats. Developmental neurobiology. vol 67. issue 7. 2007-07-31. PMID:17506495. |
the role of bdnf in modulating gaba and glycine-mediated inhibitory transmission has not been fully investigated. |
2007-07-31 |
2023-08-12 |
rat |
Rita Bardoni, Alessia Ghirri, Chiara Salio, Massimiliano Prandini, Adalberto Merigh. BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats. Developmental neurobiology. vol 67. issue 7. 2007-07-31. PMID:17506495. |
we show that application of bdnf enhanced the spontaneous release of gaba and glycine, in presence of tetrodotoxin. |
2007-07-31 |
2023-08-12 |
rat |
Rita Bardoni, Alessia Ghirri, Chiara Salio, Massimiliano Prandini, Adalberto Merigh. BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats. Developmental neurobiology. vol 67. issue 7. 2007-07-31. PMID:17506495. |
evoked gaba and glycine ipscs (eipscs) were depressed by bdnf and the coefficient of variation of eipsc amplitude was significantly increased. |
2007-07-31 |
2023-08-12 |
rat |
B F P Broekman, M Olff, F Boe. The genetic background to PTSD. Neuroscience and biobehavioral reviews. vol 31. issue 3. 2007-06-28. PMID:17126903. |
they have tested hypotheses involving key candidate genes in the serotonin (5-htt), dopamine (drd2, dat), glucocorticoid (gr), gaba (gabrb), apolipoprotein systems (apoe2), brain-derived neurotrophic factor (bdnf) and neuropeptide y (npy). |
2007-06-28 |
2023-08-12 |
Not clear |
M A Carrasco, P Castro, F J Sepulveda, J C Tapia, K Gatica, M I Davis, L G Aguay. Regulation of glycinergic and GABAergic synaptogenesis by brain-derived neurotrophic factor in developing spinal neurons. Neuroscience. vol 145. issue 2. 2007-06-26. PMID:17306467. |
amplitude and frequency of spontaneous inhibitory postsynaptic currents (sipscs) and miniature inhibitory postsynaptic currents (mipscs) associated to activation of glycine and gaba(a) receptors were augmented in neurons cultured with bdnf. |
2007-06-26 |
2023-08-12 |
mouse |
Kerri A Massey, Wagner M Zago, Darwin K Ber. BDNF up-regulates alpha7 nicotinic acetylcholine receptor levels on subpopulations of hippocampal interneurons. Molecular and cellular neurosciences. vol 33. issue 4. 2007-03-02. PMID:17029981. |
blocking transmission through nmda receptors with apv blocked the bdnf effect; increasing spontaneous excitatory activity with the gaba(a) receptor antagonist bicuculline replicated the bdnf effect. |
2007-03-02 |
2023-08-12 |
Not clear |
Eun-Jin Lee, Tricia L Gibo, Norberto M Grzywac. Dark-rearing-induced reduction of GABA and GAD and prevention of the effect by BDNF in the mouse retina. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074038. |
dark-rearing-induced reduction of gaba and gad and prevention of the effect by bdnf in the mouse retina. |
2006-12-21 |
2023-08-12 |
mouse |
Eun-Jin Lee, Tricia L Gibo, Norberto M Grzywac. Dark-rearing-induced reduction of GABA and GAD and prevention of the effect by BDNF in the mouse retina. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074038. |
third, does bdnf prevent the influence of dark-rearing on the expression of gaba and gad? |
2006-12-21 |
2023-08-12 |
mouse |
Eun-Jin Lee, Tricia L Gibo, Norberto M Grzywac. Dark-rearing-induced reduction of GABA and GAD and prevention of the effect by BDNF in the mouse retina. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074038. |
moreover, dark-reared retinas treated with bdnf showed normal expression of both gaba and gad65. |
2006-12-21 |
2023-08-12 |
mouse |
Yoshito Mizoguchi, Akihiko Kitamura, Hiroaki Wake, Hitoshi Ishibashi, Miho Watanabe, Takuya Nishimaki, Junichi Nabekur. BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074039. |
bdnf occludes gaba receptor-mediated inhibition of gaba release in rat hippocampal ca1 pyramidal neurons. |
2006-12-21 |
2023-08-12 |
rat |
Yoshito Mizoguchi, Akihiko Kitamura, Hiroaki Wake, Hitoshi Ishibashi, Miho Watanabe, Takuya Nishimaki, Junichi Nabekur. BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074039. |
during the development of the rat hippocampus, both gamma-aminobutyric acid (gaba)(b) autoreceptors and brain-derived neurotrophic factor (bdnf) play important roles in the formation of gabaergic synapses as well as in the gaba(a) receptor-mediated transmissions. |
2006-12-21 |
2023-08-12 |
rat |
Yoshito Mizoguchi, Akihiko Kitamura, Hiroaki Wake, Hitoshi Ishibashi, Miho Watanabe, Takuya Nishimaki, Junichi Nabekur. BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074039. |
while a number of studies have reported rapid effects of bdnf on gaba(a) receptor-mediated responses, the interactions between gaba(b) autoreceptors and bdnf are less clear. |
2006-12-21 |
2023-08-12 |
rat |
Yoshito Mizoguchi, Akihiko Kitamura, Hiroaki Wake, Hitoshi Ishibashi, Miho Watanabe, Takuya Nishimaki, Junichi Nabekur. BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074039. |
using conventional whole-cell patch-clamp recordings, we demonstrated here that bdnf significantly occludes baclofen-induced suppression of gaba(a) receptor-mediated transmissions in each of the preparations including hippocampal slices prepared from p14 rats, hippocampal ca1 pyramidal neurons isolated from p14 and p21 rats, and cultured hippocampal pyramidal neurons. |
2006-12-21 |
2023-08-12 |
rat |
Yoshito Mizoguchi, Akihiko Kitamura, Hiroaki Wake, Hitoshi Ishibashi, Miho Watanabe, Takuya Nishimaki, Junichi Nabekur. BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074039. |
this effect of bdnf was rapid and reversible, and was mediated via the activation of presynaptic trkb receptor tyrosine kinases, and subsequent activation of phospholipase c and protein kinase c. on the contrary, in hippocampal ca1 pyramidal neurons isolated from p7 rats, bdnf failed to occlude the gaba(b) receptor-mediated inhibition of gaba release. |
2006-12-21 |
2023-08-12 |
rat |
Yoshito Mizoguchi, Akihiko Kitamura, Hiroaki Wake, Hitoshi Ishibashi, Miho Watanabe, Takuya Nishimaki, Junichi Nabekur. BDNF occludes GABA receptor-mediated inhibition of GABA release in rat hippocampal CA1 pyramidal neurons. The European journal of neuroscience. vol 24. issue 8. 2006-12-21. PMID:17074039. |
thus, the ability of bdnf to occlude the gaba(b) receptor-mediated inhibition of gaba release develops between p7 and p14. |
2006-12-21 |
2023-08-12 |
rat |
Mathew Blurton-Jones, Mark H Tuszynsk. Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF. The Journal of comparative neurology. vol 499. issue 4. 2006-12-01. PMID:17029253. |
estradiol-induced modulation of estrogen receptor-beta and gaba within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of bdnf. |
2006-12-01 |
2023-08-12 |
rat |
Daniel S Roberts, Yinghui Hu, Ingrid V Lund, Amy R Brooks-Kayal, Shelley J Russe. Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor alpha 4 subunits in hippocampal neurons. The Journal of biological chemistry. vol 281. issue 40. 2006-11-30. PMID:16901909. |
brain-derived neurotrophic factor (bdnf)-induced synthesis of early growth response factor 3 (egr3) controls the levels of type a gaba receptor alpha 4 subunits in hippocampal neurons. |
2006-11-30 |
2023-08-12 |
Not clear |
S J Enna, Scott A Reisman, John A Stanfor. CGP 56999A, a GABA(B) receptor antagonist, enhances expression of brain-derived neurotrophic factor and attenuates dopamine depletion in the rat corpus striatum following a 6-hydroxydopamine lesion of the nigrostriatal pathway. Neuroscience letters. vol 406. issue 1-2. 2006-11-03. PMID:16890350. |
in contrast, as compared to animals receiving saline only, daily treatment with the gaba(b) receptor antagonist significantly attenuated the 6-hydroxydopamine-induced decline in da and increased the expression of bdnf in the ipsilateral striatum. |
2006-11-03 |
2023-08-12 |
human |
C Glorioso, M Sabatini, T Unger, T Hashimoto, L M Monteggia, D A Lewis, K Mirnic. Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Molecular psychiatry. vol 11. issue 7. 2006-10-31. PMID:16702976. |
however, the effect of bdnf on the expression of transcripts whose protein products are involved in gamma amino butric acid (gaba) neurotransmission has not been assessed. |
2006-10-31 |
2023-08-12 |
mouse |
C Glorioso, M Sabatini, T Unger, T Hashimoto, L M Monteggia, D A Lewis, K Mirnic. Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Molecular psychiatry. vol 11. issue 7. 2006-10-31. PMID:16702976. |
bdnf appeared to be required to maintain gene expression in the sst-npy-tac1 subclass of gaba neurons, although the absence of bdnf did not alter their general phenotype as inhibitory neurons. |
2006-10-31 |
2023-08-12 |
mouse |