| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Berninger, S Marty, F Zafra, M da Penha Berzaghi, H Thoenen, D Lindhol. GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (Cambridge, England). vol 121. issue 8. 1995-10-13. PMID:7671799. |
the differential regulation of c-fos and bdnf expression by gaba and muscimol in developing and mature hippocampal neurons is due to a switch in the ability of gabaa receptors to activate voltage-gated ca2+ channels. |
1995-10-13 |
2023-08-12 |
rat |
| B Berninger, S Marty, F Zafra, M da Penha Berzaghi, H Thoenen, D Lindhol. GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (Cambridge, England). vol 121. issue 8. 1995-10-13. PMID:7671799. |
these observations support the hypothesis that gaba might have neurotrophic effects on embryonic or perinatal hippocampal neurons, which are mediated by bdnf. |
1995-10-13 |
2023-08-12 |
rat |
| S Ahmed, B A Reynolds, S Weis. BDNF enhances the differentiation but not the survival of CNS stem cell-derived neuronal precursors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 8. 1995-09-20. PMID:7643217. |
these bdnf actions did not appear to involve the enhancement of a novel neuronal phenotype, with all effects being due to increase in the numbers and neurite outgrowth of neurons that colocalize gaba and substance p. these findings suggest that bdnf markedly enhances the antigenic and morphologic differentiation of egf-generated neuronal precursors. |
1995-09-20 |
2023-08-12 |
mouse |
| D Lindholm, E Castrén, M Berzaghi, A Blöchl, H Thoene. Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity. Journal of neurobiology. vol 25. issue 11. 1995-03-10. PMID:7852991. |
the production of ngf and bdnf is controlled by neuronal activity: up-regulation by glutamate and acetylcholine, down-regulation by gamma-aminobutyric acid. |
1995-03-10 |
2023-08-12 |
Not clear |
| K Mizuno, J Carnahan, H Naw. Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons. Developmental biology. vol 165. issue 1. 1994-10-19. PMID:8088442. |
brain-derived neurotrophic factor (bdnf) specifically elevated cellular gaba content in striatal culture without altering neuronal survival. |
1994-10-19 |
2023-08-12 |
rat |
| K Mizuno, J Carnahan, H Naw. Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons. Developmental biology. vol 165. issue 1. 1994-10-19. PMID:8088442. |
an increase in gaba content in the striatum was also observed following bdnf injections into the cerebroventricle of neonatal rats. |
1994-10-19 |
2023-08-12 |
rat |
| V E Koliatsos, D L Price, G K Gouras, M H Cayouette, L E Burton, J W Winslo. Highly selective effects of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 on intact and injured basal forebrain magnocellular neurons. The Journal of comparative neurology. vol 343. issue 2. 1994-08-10. PMID:8027442. |
the present investigation was designed to test, in a comparative fashion, the in vivo effects of human recombinant ngf, bdnf, and nt-3 with confirmed activities in vitro on cholinergic and gamma-aminobutyric acid (gaba)-ergic bnc neurons. |
1994-08-10 |
2023-08-12 |
human |
| T Massamiri, M Khrestchatisky, Y Ben-Ar. Induction of c-fos mRNA expression in an in vitro hippocampal slice model of adult rats after kainate but not gamma-aminobutyric acid or bicuculline treatment. Neuroscience letters. vol 166. issue 1. 1994-06-20. PMID:8190362. |
our results also demonstrate a lack of induction of c-fos, zifl268 and bdnf after short-time treatment of either adult or newborn hippocampal slices with gaba or bicuculline. |
1994-06-20 |
2023-08-12 |
rat |
| C Hyman, M Juhasz, C Jackson, P Wright, N Y Ip, R M Lindsa. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:8283241. |
bdnf, nt-3, or nt-4/5 also produced dose-dependent elevations of 2-3-fold in gaba uptake activity. |
1994-02-16 |
2023-08-12 |
rat |
| C Hyman, M Juhasz, C Jackson, P Wright, N Y Ip, R M Lindsa. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:8283241. |
gad activity was increased by bdnf (1.8-fold) and nt-3 (threefold) treatment, but not by nt-4/5, whereas gaba content was increased to a similar extent by all three neurotrophins. |
1994-02-16 |
2023-08-12 |
rat |
| H Nawa, Y Bessho, J Carnahan, S Nakanishi, K Mizun. Regulation of neuropeptide expression in cultured cerebral cortical neurons by brain-derived neurotrophic factor. Journal of neurochemistry. vol 60. issue 2. 1993-02-09. PMID:8093484. |
brain-derived neurotrophic factor (bdnf) specifically increased contents of the neuropeptides somatostatin (som) and neuropeptide y (npy), but its effect on contents of cholecystokinin octapeptide and gaba was much less significant. |
1993-02-09 |
2023-08-12 |
Not clear |
| C A Altar, C B Boylan, C Jackson, S Hershenson, J Miller, S J Wiegand, R M Lindsay, C Hyma. Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 23. 1993-01-07. PMID:1454818. |
neither striatal dopamine, gamma-aminobutyric acid, nor acetylcholine high-affinity uptake or the synthetic enzymes for these neurotransmitters was altered by bdnf. |
1993-01-07 |
2023-08-11 |
rat |
| F Zafra, E Castrén, H Thoenen, D Lindhol. Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 22. 1991-12-26. PMID:1658793. |
here we demonstrate that the balance between the activity of the glutamatergic and gamma-aminobutyric acid (gaba)ergic systems controls the physiological levels of bdnf and ngf mrnas in hippocampal neurons in vitro and in vivo. |
1991-12-26 |
2023-08-11 |
Not clear |
| F Zafra, E Castrén, H Thoenen, D Lindhol. Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 22. 1991-12-26. PMID:1658793. |
the refined and rapid regulation of bdnf and ngf synthesis by the glutamate and gaba transmitter systems suggests that bdnf and ngf might be involved in activity-dependent synaptic plasticity. |
1991-12-26 |
2023-08-11 |
Not clear |