| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bárbara Aisa, Francisco J Gil-Bea, Maite Solas, Mónica García-Alloza, Christopher P Chen, Mitchell K Lai, Paul T Francis, María Javier Ramíre. Altered NCAM expression associated with the cholinergic system in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 20. issue 2. 2010-09-07. PMID:20164549. |
we have studied, in postmortem brain tissue, the relationship between levels of synaptic markers (ncam and bdnf), neurochemical measurements (cholinacetyltransferase activity, serotonin, dopamine, gaba, and glutamate levels), and clinical data (cognitive status measured as mmse score). |
2010-09-07 |
2023-08-12 |
Not clear |
| Valentina De Chiara, Francesco Angelucci, Silvia Rossi, Alessandra Musella, Francesca Cavasinni, Cristina Cantarella, Giorgia Mataluni, Lucia Sacchetti, Francesco Napolitano, Maura Castelli, Carlo Caltagirone, Giorgio Bernardi, Mauro Maccarrone, Alessandro Usiello, Diego Centonz. Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554863. |
the effect of bdnf was restricted to cb(1)rs controlling gaba-mediated ipscs (cb(1)r(gaba)), whereas cb(1)rs modulating glutamate transmission and gaba(b) receptors were not affected. |
2010-07-02 |
2023-08-12 |
mouse |
| Valentina De Chiara, Francesco Angelucci, Silvia Rossi, Alessandra Musella, Francesca Cavasinni, Cristina Cantarella, Giorgia Mataluni, Lucia Sacchetti, Francesco Napolitano, Maura Castelli, Carlo Caltagirone, Giorgio Bernardi, Mauro Maccarrone, Alessandro Usiello, Diego Centonz. Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554863. |
the action of bdnf on cb(1)r(gaba) function was tyrosine kinase dependent and was complete even after receptor sensitization with cocaine or environmental manipulations activating the dopamine (da)-dependent reward system. |
2010-07-02 |
2023-08-12 |
mouse |
| Valentina De Chiara, Francesco Angelucci, Silvia Rossi, Alessandra Musella, Francesca Cavasinni, Cristina Cantarella, Giorgia Mataluni, Lucia Sacchetti, Francesco Napolitano, Maura Castelli, Carlo Caltagirone, Giorgio Bernardi, Mauro Maccarrone, Alessandro Usiello, Diego Centonz. Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554863. |
in mice lacking one copy of the bdnf gene (bdnf(+/-)), cb(1)r(gaba) responses were potentiated and were preserved from the action of haloperidol, a da d(2) receptor (d(2)r) antagonist able to fully abolish cb(1)r(gaba) function in rewarded animals. |
2010-07-02 |
2023-08-12 |
mouse |
| Valentina De Chiara, Francesco Angelucci, Silvia Rossi, Alessandra Musella, Francesca Cavasinni, Cristina Cantarella, Giorgia Mataluni, Lucia Sacchetti, Francesco Napolitano, Maura Castelli, Carlo Caltagirone, Giorgio Bernardi, Mauro Maccarrone, Alessandro Usiello, Diego Centonz. Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554863. |
accordingly, 5 d cocaine exposure both reduced striatal bdnf levels and increased cb(1)r(gaba) activity, through a mechanism dependent on d(2)rs. |
2010-07-02 |
2023-08-12 |
mouse |
| Yukihiko Shirayama, Shigeyuki Chak. Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Current neuropharmacology. vol 4. issue 4. 2010-06-10. PMID:18654637. |
first, we discuss the roles of several neurotransmitters and neuropeptides in the functioning of the nac, including dopamine, glutamate, gamma-aminobutyric acid (gaba), acetylcholine, serotonin, dynorphin, enkephaline, brain-derived neurotrophic factor (bdnf), camp response element-binding protein (creb), melanin-concentrating hormone (mch) and cocaine- and amphetamine-regulated transcript (cart). |
2010-06-10 |
2023-08-12 |
Not clear |
| Giuseppina Giusi, Rosa Maria Facciolo, Maria Rende, Raffaella Alò, Anna Di Vito, Simona Salerno, Sabrina Morelli, Loredana De Bartolo, Enrico Drioli, Marcello Canonac. Distinct alpha subunits of the GABAA receptor are responsible for early hippocampal silent neuron-related activities. Hippocampus. vol 19. issue 11. 2010-04-27. PMID:19338020. |
in this study, growth of hamster hippocampal neurons on biohybrid membrane substrates allowed us to show for the first time that the two major gaba(a) alpha receptor subunits (alpha(2,5)) are capable of early neuronal shaping plus expression differences of some of the main neuronal cytoskeletal factors (gap-43, the neurotrophin--bdnf) and of gluergic subtypes. |
2010-04-27 |
2023-08-12 |
Not clear |
| W Sun, R J Salv. Brain derived neurotrophic factor and neurotrophic factor 3 modulate neurotransmitter receptor expressions on developing spiral ganglion neurons. Neuroscience. vol 164. issue 4. 2010-02-19. PMID:19778585. |
to address this question, the whole-cell patch clamp recording technique was used to determine what effect nt-3 and bdnf had on the function and expression of glutamate, gaba and glycine receptors (glyr) on sgn of cochlea from postnatal c57 mouse. |
2010-02-19 |
2023-08-12 |
mouse |
| W Sun, R J Salv. Brain derived neurotrophic factor and neurotrophic factor 3 modulate neurotransmitter receptor expressions on developing spiral ganglion neurons. Neuroscience. vol 164. issue 4. 2010-02-19. PMID:19778585. |
nt-3, and to a lesser extent bdnf, enhanced the expression of gaba receptors and had comparatively little effect on glutamate receptors. |
2010-02-19 |
2023-08-12 |
mouse |
| Naoki Goto, Reiji Yoshimura, Shingo Kakeda, Junji Moriya, Kenji Hayashi, Atsuko Ikenouchi-Sugita, Wakako Umene-Nakano, Hikaru Hori, Nobuhisa Ueda, Yukunori Korogi, Jun Nakamur. Associations between plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) and negative symptoms or cognitive impairments in early-stage schizophrenia. Human psychopharmacology. vol 24. issue 8. 2010-02-18. PMID:19946939. |
blood levels of bdnf and catecholamine metabolites and brain gaba levels using 1h-mrs were measured in 18 schizophrenic patients (nine males, nine females; age range 13-52 year). |
2010-02-18 |
2023-08-12 |
Not clear |
| Hervé Fiorentino, Nicola Kuczewski, Diabe Diabira, Nadine Ferrand, Menelas N Pangalos, Christophe Porcher, Jean-Luc Gaiars. GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 37. 2009-10-02. PMID:19759312. |
gaba(b) receptor activation triggers bdnf release and promotes the maturation of gabaergic synapses. |
2009-10-02 |
2023-08-12 |
mouse |
| Hervé Fiorentino, Nicola Kuczewski, Diabe Diabira, Nadine Ferrand, Menelas N Pangalos, Christophe Porcher, Jean-Luc Gaiars. GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 37. 2009-10-02. PMID:19759312. |
using whole-cell patch-clamp recordings on newborn mouse hippocampi lacking functional gaba(b) receptors (gaba(b)-rs) and time-lapse fluorescence imaging on cultured hippocampal neurons expressing gfp-tagged brain-derived neurotrophic factor (bdnf), we found that activation of metabotropic gaba(b) receptors (gaba(b)-rs) triggers secretion of bdnf and promotes the development of perisomatic gabaergic synapses in the newborn mouse hippocampus. |
2009-10-02 |
2023-08-12 |
mouse |
| H N Zhang, M C K. Seizure activity involved in the up-regulation of BDNF mRNA expression by activation of central mu opioid receptors. Neuroscience. vol 161. issue 1. 2009-09-21. PMID:19303919. |
this study provides supporting evidence that seizure activity plays an important role in the up-regulation of bdnf mrna expression elicited by central mor activation and that decreased inhibitory action of gabaergic system through the modulation on gaba receptor synaptic function by central mor activation is involved in its regulation of bdnf mrna expression. |
2009-09-21 |
2023-08-12 |
rat |
| Mamoru Fukuchi, Takuya Nii, Naoki Ishimaru, Aya Minamino, Daichi Hara, Ichiro Takasaki, Akiko Tabuchi, Masaaki Tsud. Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions. Neuroscience research. vol 65. issue 1. 2009-09-03. PMID:19463867. |
the mrna expression for brain-derived neurotrophic factor (bdnf) and the alpha4 subunit of the gaba(a) receptor (gaba(a)ralpha4), known to be involved in epileptogenesis, was up-regulated, with the increase in bdnf exon i-ix mrna expression being remarkable, whereas that for gaba(a)rgamma2, gad65 and 67, and the k(+)/cl(-) co-transporter kcc2, which are responsible for the development of gabaergic inhibitory neurons, was down-regulated. |
2009-09-03 |
2023-08-12 |
rat |
| Ana Silva, Jorge Pereira, Catarina R Oliveira, João Bettencourt Relvas, A Cristina Reg. BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype. Journal of neuroscience research. vol 87. issue 9. 2009-08-14. PMID:19267421. |
moreover, cells treated with bdnf plus b27 supplement acquired a gamma-aminobutyric acid (gaba)-ergic phenotype and showed increased survival. |
2009-08-14 |
2023-08-12 |
mouse |
| Amy R Brooks-Kayal, Yogendra H Raol, Shelley J Russe. Alteration of epileptogenesis genes. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 6. issue 2. 2009-06-05. PMID:19332325. |
the mechanisms that regulate differential expression of gaba(a) receptor subunits in hippocampus after se have recently been identified, and include the creb-icer, jak-stat, bdnf, and egr3 signaling pathways. |
2009-06-05 |
2023-08-12 |
Not clear |
| Marina Snapyan, Morgane Lemasson, Monika S Brill, Mathieu Blais, Mireille Massouh, Jovica Ninkovic, Claude Gravel, François Berthod, Magdalena Götz, Philip A Barker, André Parent, Armen Saghatelya. Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 13. 2009-04-23. PMID:19339612. |
interestingly, gaba released from neuroblasts induces ca(2+)-dependent insertion of high-affinity trkb receptors on the plasma membrane of astrocytes that trap extracellular bdnf. |
2009-04-23 |
2023-08-12 |
Not clear |
| Michael Ogier, David M Kat. Breathing dysfunction in Rett syndrome: understanding epigenetic regulation of the respiratory network. Respiratory physiology & neurobiology. vol 164. issue 1-2. 2009-04-15. PMID:18534925. |
the picture that is emerging is one of defects in synaptic transmission throughout the brainstem respiratory network associated with abnormal expression in several neurochemical signaling systems, including brain-derived neurotrophic factor (bdnf), biogenic amines and gamma-amino-butyric acid (gaba). |
2009-04-15 |
2023-08-12 |
mouse |
| Harald D Müller, Angelika Neder, Clemens Sommer, Wolf-Rüdiger Schäbit. Different postischemic protein expression of the GABA(A) receptor alpha2 subunit and the plasticity-associated protein MAP1B after treatment with BDNF versus G-CSF in the rat brain. Restorative neurology and neuroscience. vol 27. issue 1. 2009-04-14. PMID:19164851. |
different postischemic protein expression of the gaba(a) receptor alpha2 subunit and the plasticity-associated protein map1b after treatment with bdnf versus g-csf in the rat brain. |
2009-04-14 |
2023-08-12 |
rat |
| Sudhir Sivakumaran, Majid H Mohajerani, Enrico Cherubin. At immature mossy-fiber-CA3 synapses, correlated presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 8. 2009-03-16. PMID:19244539. |
at immature mossy-fiber-ca3 synapses, correlated presynaptic and postsynaptic activity persistently enhances gaba release and network excitability via bdnf and camp-dependent pka. |
2009-03-16 |
2023-08-12 |
rat |