| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicola Kuczewski, Celine Fuchs, Nadine Ferrand, Jasmina N Jovanovic, Jean-Luc Gaiarsa, Christophe Porche. Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression. Journal of neurochemistry. vol 118. issue 4. 2011-09-16. PMID:21255015. |
in a previous study, we reported that gaba(b) receptor activation triggers secretion of brain-derived neurotrophic factor (bdnf) and promotes the functional maturation of gabaergic synapses in the developing rat hippocampus. |
2011-09-16 |
2023-08-12 |
rat |
| Nicola Kuczewski, Celine Fuchs, Nadine Ferrand, Jasmina N Jovanovic, Jean-Luc Gaiarsa, Christophe Porche. Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression. Journal of neurochemistry. vol 118. issue 4. 2011-09-16. PMID:21255015. |
to identify the signalling pathway linking gaba(b) receptor activation to bdnf secretion in these cells, we have now used the phosphorylated form of the camp response element-binding protein as a biological sensor for endogenous bdnf release. |
2011-09-16 |
2023-08-12 |
rat |
| Nicola Kuczewski, Celine Fuchs, Nadine Ferrand, Jasmina N Jovanovic, Jean-Luc Gaiarsa, Christophe Porche. Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression. Journal of neurochemistry. vol 118. issue 4. 2011-09-16. PMID:21255015. |
in the present study, we show that gaba(b) receptor-induced secretion of bdnf relies on the activation of phospholipase c, followed by the formation of diacylglycerol, activation of protein kinase c, and the opening of l-type voltage-dependent ca(2+) channels. |
2011-09-16 |
2023-08-12 |
rat |
| Nicola Kuczewski, Celine Fuchs, Nadine Ferrand, Jasmina N Jovanovic, Jean-Luc Gaiarsa, Christophe Porche. Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression. Journal of neurochemistry. vol 118. issue 4. 2011-09-16. PMID:21255015. |
we further show that once released by gaba(b) receptor activation, bdnf increases the membrane expression of β(2/3) -containing gaba(a) receptors in neuronal cultures. |
2011-09-16 |
2023-08-12 |
rat |
| Fouad Lemtiri-Chlieh, Eric S Levin. BDNF evokes release of endogenous cannabinoids at layer 2/3 inhibitory synapses in the neocortex. Journal of neurophysiology. vol 104. issue 4. 2011-08-30. PMID:20719932. |
we explored a potential interaction between bdnf and endogenous cannabinoid (endocannabinoid) signaling because activation of type 1 cannabinoid (cb1) receptors potently regulates γ-aminobutyric acid (gaba) release and both trkb tyrosine kinase receptors and cb1 receptors are highly expressed at synapses in neocortical layer 2/3. |
2011-08-30 |
2023-08-12 |
Not clear |
| Fouad Lemtiri-Chlieh, Eric S Levin. BDNF evokes release of endogenous cannabinoids at layer 2/3 inhibitory synapses in the neocortex. Journal of neurophysiology. vol 104. issue 4. 2011-08-30. PMID:20719932. |
in addition, bdnf decreased the frequency but not the amplitude of action potential-independent miniature ipscs and bdnf did not alter the postsynaptic response to locally applied gaba. |
2011-08-30 |
2023-08-12 |
Not clear |
| Christophe Porcher, Caroline Hatchett, Rebecca E Longbottom, Kristina McAinch, Talvinder S Sihra, Stephen J Moss, Alex M Thomson, Jasmina N Jovanovi. Positive feedback regulation between gamma-aminobutyric acid type A (GABA(A)) receptor signaling and brain-derived neurotrophic factor (BDNF) release in developing neurons. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21474450. |
positive feedback regulation between gamma-aminobutyric acid type a (gaba(a)) receptor signaling and brain-derived neurotrophic factor (bdnf) release in developing neurons. |
2011-08-30 |
2023-08-12 |
Not clear |
| Christophe Porcher, Caroline Hatchett, Rebecca E Longbottom, Kristina McAinch, Talvinder S Sihra, Stephen J Moss, Alex M Thomson, Jasmina N Jovanovi. Positive feedback regulation between gamma-aminobutyric acid type A (GABA(A)) receptor signaling and brain-derived neurotrophic factor (BDNF) release in developing neurons. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21474450. |
we further demonstrate that gaba(a)r activity triggers release of the brain-derived neurotrophic factor (bdnf), which, in turn by activating trkb receptors, mediates the observed increase in cell surface expression of gaba(a)rs. |
2011-08-30 |
2023-08-12 |
Not clear |
| Christophe Porcher, Caroline Hatchett, Rebecca E Longbottom, Kristina McAinch, Talvinder S Sihra, Stephen J Moss, Alex M Thomson, Jasmina N Jovanovi. Positive feedback regulation between gamma-aminobutyric acid type A (GABA(A)) receptor signaling and brain-derived neurotrophic factor (BDNF) release in developing neurons. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21474450. |
the increase in gaba(a)r surface levels occurs due to an inhibition of the receptor endocytosis by bdnf, whereas the receptor reinsertion into the plasma membrane remains unaltered. |
2011-08-30 |
2023-08-12 |
Not clear |
| Christophe Porcher, Caroline Hatchett, Rebecca E Longbottom, Kristina McAinch, Talvinder S Sihra, Stephen J Moss, Alex M Thomson, Jasmina N Jovanovi. Positive feedback regulation between gamma-aminobutyric acid type A (GABA(A)) receptor signaling and brain-derived neurotrophic factor (BDNF) release in developing neurons. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21474450. |
thus, gaba(a)r activity is a potent regulator of the bdnf release during neuronal development, and at the same time, it is strongly enhanced by the activity of the bdnf/trkb/pi3k/pkc signaling pathway. |
2011-08-30 |
2023-08-12 |
Not clear |
| Se Jin Jeon, So Young Rhee, Jung Eun Seo, Hae Rang Bak, Sung Hoon Lee, Jong Hoon Ryu, Jae Hoon Cheong, Chan Young Shin, Gun-Hee Kim, Yong Soo Lee, Kwang Ho K. Oroxylin A increases BDNF production by activation of MAPK-CREB pathway in rat primary cortical neuronal culture. Neuroscience research. vol 69. issue 3. 2011-07-29. PMID:21145362. |
gaba(a) antagonist bicuculline mimicked the effects of oroxylin a on bdnf production as well as mapk-creb pathway. |
2011-07-29 |
2023-08-12 |
rat |
| Se Jin Jeon, So Young Rhee, Jung Eun Seo, Hae Rang Bak, Sung Hoon Lee, Jong Hoon Ryu, Jae Hoon Cheong, Chan Young Shin, Gun-Hee Kim, Yong Soo Lee, Kwang Ho K. Oroxylin A increases BDNF production by activation of MAPK-CREB pathway in rat primary cortical neuronal culture. Neuroscience research. vol 69. issue 3. 2011-07-29. PMID:21145362. |
the results from the present study suggest that the calcium and p-creb dependent induction of bdnf expression, possibly via activation of synaptic nmda receptor through the blockade of gaba(a) activity in cortical neuronal circuitry, might be responsible for the neuroprotective or memory enhancing effects of oroxylin a. |
2011-07-29 |
2023-08-12 |
rat |
| Carlos Sánchez-Huertas, Beatriz Ric. CREB-Dependent Regulation of GAD65 Transcription by BDNF/TrkB in Cortical Interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 21. issue 4. 2011-07-13. PMID:20739478. |
previous studies have suggested that the expression levels of the rate-limiting gaba synthetic enzyme, gad65, depend on brain derived neurotrophic factor (bdnf)/trkb activation. |
2011-07-13 |
2023-08-12 |
Not clear |
| Se Jin Park, Dong Hyun Kim, Jong Min Kim, Chan Young Shin, Jae Hoon Cheong, Kwang Ho Ko, Jong Hoon Ry. Mismatch between changes in baicalein-induced memory-related biochemical parameters and behavioral consequences in mouse. Brain research. vol 1355. 2011-06-20. PMID:20691671. |
these results suggest that the reasons why baicalein does not exert cognitive enhancement although it enhances the expression levels of perk, pcreb, and bdnf are, in part, derived from its gaba(a) receptor agonistic property which is antagonized by flumazenil. |
2011-06-20 |
2023-08-12 |
mouse |
| L Mou, S A Heldt, K J Ressle. Rapid brain-derived neurotrophic factor-dependent sequestration of amygdala and hippocampal GABA(A) receptors via different tyrosine receptor kinase B-mediated phosphorylation pathways. Neuroscience. vol 176. 2011-06-01. PMID:21195749. |
in both hippocampal and amygdala cultures, we found a >60% reduction in surface gaba(a)rα1 within 5 min of bdnf treatment. |
2011-06-01 |
2023-08-12 |
mouse |
| Ana M Sebastião, Natália Assaife-Lopes, Maria J Diógenes, Sandra H Vaz, Joaquim A Ribeir. Modulation of brain-derived neurotrophic factor (BDNF) actions in the nervous system by adenosine A(2A) receptors and the role of lipid rafts. Biochimica et biophysica acta. vol 1808. issue 5. 2011-05-19. PMID:20603099. |
in this paper we review some novel aspects related to the way adenosine a(2a) receptors (a(2a)r) modulate the action of bdnf or its high-affinity receptors, the trkb receptors, on synaptic transmission and plasticity, as well as upon cholinergic currents and gaba transporters. |
2011-05-19 |
2023-08-12 |
Not clear |
| Plínio Cabrera Casarotto, Valquiria Camin de Bortoli, Fernando Morgan de Aguiar Corrêa, Leonardo Barbosa Moraes Resstel, Hélio Zangross. Panicolytic-like effect of BDNF in the rat dorsal periaqueductal grey matter: the role of 5-HT and GABA. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:20047714. |
panicolytic-like effect of bdnf in the rat dorsal periaqueductal grey matter: the role of 5-ht and gaba. |
2011-01-25 |
2023-08-12 |
rat |
| John F Cryan, David A Slatter. GABAB receptors and depression. Current status. Advances in pharmacology (San Diego, Calif.). vol 58. 2010-11-01. PMID:20655491. |
the gaba(b) receptor system has been shown to have substantial interactions with the serotonergic system and neurotrophic factors, such as bdnf. |
2010-11-01 |
2023-08-12 |
mouse |
| Hui Lu, Pei-Lin Cheng, Byung Kook Lim, Nina Khoshnevisrad, Mu-Ming Po. Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. Neuron. vol 67. issue 5. 2010-10-01. PMID:20826313. |
elevated bdnf after cocaine withdrawal facilitates ltp in medial prefrontal cortex by suppressing gaba inhibition. |
2010-10-01 |
2023-08-12 |
rat |
| Kristy M McClellan, Matthew S Stratton, Stuart A Tobe. Roles for gamma-aminobutyric acid in the development of the paraventricular nucleus of the hypothalamus. The Journal of comparative neurology. vol 518. issue 14. 2010-09-16. PMID:20506472. |
changes in cell position and protein expression subsequent to disruption of gaba signaling may be due, in part, to changes in nnos and bdnf signaling. |
2010-09-16 |
2023-08-12 |
mouse |