| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bharanidharan Shanmugasundaram, Yogesh D Aher, Jana Aradska, Marija Ilic, Daniel Daba Feyissa, Predrag Kalaba, Nilima Y Aher, Vladimir Dragacevic, Babak Saber Marouf, Thierry Langer, Harald H Sitte, Harald Hoeger, Gert Lubec, Volker Kor. R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity. PloS one. vol 12. issue 6. 2017-10-02. PMID:28644892. |
synaptic levels of dopamine receptors d1r, d2r, dopamine transporter (dat), and its phosphorylated form (ph-dat) in dg tissue 4 h after ltp induction were quantified by western blot analysis. |
2017-10-02 |
2023-08-13 |
rat |
| Alex Iranzo, Joan Santamaría, Francesc Valldeoriola, Monica Serradell, Manel Salamero, Carles Gaig, Aida Niñerola-Baizán, Raquel Sánchez-Valle, Albert Lladó, Roberto De Marzi, Ambra Stefani, Klaus Seppi, Javier Pavia, Birgit Högl, Werner Poewe, Eduard Tolosa, Francisco Lomeñ. Dopamine transporter imaging deficit predicts early transition to synucleinopathy in idiopathic rapid eye movement sleep behavior disorder. Annals of neurology. vol 82. issue 3. 2017-10-02. PMID:28833467. |
to determine the usefulness of dopamine transporter (dat) imaging to identify idiopathic rapid eye movement sleep behavior disorder (irbd) patients at risk for short-term development of clinically defined synucleinopathy. |
2017-10-02 |
2023-08-13 |
Not clear |
| Franziska Richter, Lauryn Gabby, Kimberly A McDowell, Caitlyn K Mulligan, Krystal De La Rosa, Pedrom C Sioshansi, Farzad Mortazavi, Ingrid Cely, Larry C Ackerson, Linda Tsan, Niall P Murphy, Nigel T Maidment, Marie-Françoise Chessele. Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice. Neurobiology of aging. vol 51. 2017-09-28. PMID:28038352. |
how genetic variations in the dopamine transporter (dat) combined with exposure to environmental toxins modulate the risk of parkinson's disease remains unclear. |
2017-09-28 |
2023-08-13 |
mouse |
| Ameya Kasture, Ali El-Kasaby, Daniel Szöllősi, H M Mazhar Asjad, Alexandra Grimm, Thomas Stockner, Thomas Hummel, Michael Freissmuth, Sonja Suci. Functional Rescue of a Misfolded The Journal of biological chemistry. vol 291. issue 40. 2017-09-18. PMID:27481941. |
functional rescue of a misfolded folding-defective mutants of the human dopamine transporter (dat) cause a syndrome of infantile dystonia/parkinsonism. |
2017-09-18 |
2023-08-13 |
human |
| Ayumi Watanabe, Yusuke Inoue, Yuji Asano, Kei Kikuchi, Hiroki Miyatake, Takanobu Tokushig. Examination of a Method to Determine the Reference Region for Calculating the Specific Binding Ratio in Dopamine Transporter Imaging. Nihon Hoshasen Gijutsu Gakkai zasshi. vol 73. issue 4. 2017-09-18. PMID:28428472. |
for quantitative indicators for dopamine transporter (dat) imaging. |
2017-09-18 |
2023-08-13 |
Not clear |
| Kirsten R Müller-Vahl, Gesa Loeber, Alexandra Kotsiari, Linda Müller-Engling, Helge Frielin. Gilles de la Tourette syndrome is associated with hypermethylation of the dopamine D2 receptor gene. Journal of psychiatric research. vol 86. 2017-09-12. PMID:27883923. |
bisulfite sequencing was used to measure peripheral dna methylation of the dopamine transporter (dat), the dopamine d2 receptor (drd2), and the catechol-o-methyltransferase (comt) genes. |
2017-09-12 |
2023-08-13 |
Not clear |
| Michelle A Sahai, Colin Davidson, George Khelashvili, Vincenzo Barrese, Neelakshi Dutta, Harel Weinstein, Jolanta Opacka-Juffr. Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances - The case of the benzofuran 5-MAPB. Progress in neuro-psychopharmacology & biological psychiatry. vol 75. 2017-09-07. PMID:27890676. |
novel psychoactive substances (nps) are increasingly prevalent world-wide although their pharmacological characteristics are largely unknown; those with stimulant properties, due to interactions with the dopamine transporter (dat), have addictive potential which their users may not realise. |
2017-09-07 |
2023-08-13 |
rat |
| M Mereu, G Contarini, E F Buonaguro, G Latte, F Managò, F Iasevoli, A de Bartolomeis, F Papale. Dopamine transporter (DAT) genetic hypofunction in mice produces alterations consistent with ADHD but not schizophrenia or bipolar disorder. Neuropharmacology. vol 121. 2017-09-05. PMID:28454982. |
dopamine transporter (dat) genetic hypofunction in mice produces alterations consistent with adhd but not schizophrenia or bipolar disorder. |
2017-09-05 |
2023-08-13 |
mouse |
| M Mereu, G Contarini, E F Buonaguro, G Latte, F Managò, F Iasevoli, A de Bartolomeis, F Papale. Dopamine transporter (DAT) genetic hypofunction in mice produces alterations consistent with ADHD but not schizophrenia or bipolar disorder. Neuropharmacology. vol 121. 2017-09-05. PMID:28454982. |
dopamine transporter (dat) genetics might be potentially implicated in all these disorders. |
2017-09-05 |
2023-08-13 |
mouse |
| Jeffery N Talbot, Laura M Geffert, Jessica E Jorvig, Ruben I Goldstein, Cienna L Nielsen, Nicholas E Wolters, Mary Ellen Amos, Caitlin A Munro, Elizabeth Dallman, Maddalena Mereu, Gianluigi Tanda, Jonathan L Katz, Martín Indarte, Jeffry D Madura, Hailey Choi, Rehana K Leak, Christopher K Surrat. Rapid and sustained antidepressant properties of an NMDA antagonist/monoamine reuptake inhibitor identified via transporter-based virtual screening. Pharmacology, biochemistry, and behavior. vol 150-151. 2017-08-31. PMID:27569602. |
a 3-d dopamine transporter (dat) computer model was used to virtually screen a commercially available small molecule library for high dat affinity drug-like compounds. |
2017-08-31 |
2023-08-13 |
mouse |
| Ismael Huertas, Silvia Jesús, José Antonio Lojo, Francisco Javier García-Gómez, María Teresa Cáceres-Redondo, Juan Manuel Oropesa-Ruiz, Fátima Carrillo, Laura Vargas-Gonzalez, Juan Francisco Martín Rodríguez, Pilar Gómez-Garre, David García-Solís, Pablo Mi. Lower levels of uric acid and striatal dopamine in non-tremor dominant Parkinson's disease subtype. PloS one. vol 12. issue 3. 2017-08-22. PMID:28358829. |
our aim was to investigate whether pd motor subtypes differ in their levels of ua, and if these differences correlate with the degree of dopamine transporter (dat) availability. |
2017-08-22 |
2023-08-13 |
Not clear |
| Chang-Chih Huang, Shin-Chang Kuo, Yi-Wei Yeh, Chun-Yen Chen, Che-Hung Yen, Chih-Sung Liang, Pei-Shen Ho, Ru-Band Lu, San-Yuan Huan. The SLC6A3 gene possibly affects susceptibility to late-onset alcohol dependence but not specific personality traits in a Han Chinese population. PloS one. vol 12. issue 2. 2017-08-15. PMID:28182634. |
the purpose of this study was to determine whether the solute carrier family 6 member 3 (slc6a3) gene (also known as the dopamine transporter dat gene) was associated with ad, and whether variants in the slc6a3 locus were associated with specific personality traits in patients with ad. |
2017-08-15 |
2023-08-13 |
Not clear |
| Ping Su, Fang Li. A peptide disrupting the D2R-DAT interaction protects against dopamine neurotoxicity. Experimental neurology. vol 295. 2017-08-14. PMID:28579325. |
previous studies have shown that both dopamine d2 receptor (d2r) and dopamine transporter (dat) are involved in dopamine neurotoxicity. |
2017-08-14 |
2023-08-13 |
Not clear |
| Ping Su, Fang Li. A peptide disrupting the D2R-DAT interaction protects against dopamine neurotoxicity. Experimental neurology. vol 295. 2017-08-14. PMID:28579325. |
we previously found that dat can form a protein complex with d2r and its cell surface expression is facilitated via d2r-dat interaction, which regulates dopamine reuptake and intracellular dopamine levels. |
2017-08-14 |
2023-08-13 |
Not clear |
| Ping Su, Fang Li. A peptide disrupting the D2R-DAT interaction protects against dopamine neurotoxicity. Experimental neurology. vol 295. 2017-08-14. PMID:28579325. |
here we found that an interfering peptide (dat-s1) disrupting the d2r-dat interaction protects neurons against dopamine neurotoxicity, and this effect is mediated by inhibiting dat cell surface expression and inhibiting both caspase-3 and parp-1 cleavage. |
2017-08-14 |
2023-08-13 |
Not clear |
| Ashlynn I Gerth, Amber L Alhadeff, Harvey J Grill, Mitchell F Roitma. Regional influence of cocaine on evoked dopamine release in the nucleus accumbens core: A role for the caudal brainstem. Brain research. vol 1655. 2017-08-08. PMID:27789280. |
cocaine increases dopamine concentration in the nucleus accumbens through competitive binding to the dopamine transporter (dat). |
2017-08-08 |
2023-08-13 |
Not clear |
| Ashlynn I Gerth, Amber L Alhadeff, Harvey J Grill, Mitchell F Roitma. Regional influence of cocaine on evoked dopamine release in the nucleus accumbens core: A role for the caudal brainstem. Brain research. vol 1655. 2017-08-08. PMID:27789280. |
however, it also increases the frequency of dopamine release events, a finding that cannot be explained by action at the dat alone. |
2017-08-08 |
2023-08-13 |
Not clear |
| Ashlynn I Gerth, Amber L Alhadeff, Harvey J Grill, Mitchell F Roitma. Regional influence of cocaine on evoked dopamine release in the nucleus accumbens core: A role for the caudal brainstem. Brain research. vol 1655. 2017-08-08. PMID:27789280. |
the magnitude of dopamine release ([da]max) as well as the latency to decay to fifty percent of the maximum (t(1/2); index of dat activity) by each stimulation train were recorded. |
2017-08-08 |
2023-08-13 |
Not clear |
| David J Brook. Molecular imaging of dopamine transporters. Ageing research reviews. vol 30. 2017-08-07. PMID:26802555. |
the dopamine transporter (dat) is responsible for clearance of dopamine from the synaptic cleft after its release. |
2017-08-07 |
2023-08-13 |
human |
| David J Brook. Molecular imaging of dopamine transporters. Ageing research reviews. vol 30. 2017-08-07. PMID:26802555. |
imaging dat availability provides a measure of dopamine terminal function and a method for detecting the striatal dopamine terminal dysfunction present in idiopathic parkinson's disease (pd) and atypical neurodegenerative parkinsonian disorders such as multiple system atrophy (msa), progressive supranuclear palsy (psp), and corticobasal degeneration (cbd). |
2017-08-07 |
2023-08-13 |
human |