| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas J F Angenoorth, Stevan Stankovic, Marco Niello, Marion Holy, Simon D Brandt, Harald H Sitte, Julian Maie. Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1-3 and Human Plasma Membrane Monoamine Transporter. International journal of molecular sciences. vol 22. issue 23. 2021-12-10. PMID:34884800. |
many psychoactive compounds have been shown to primarily interact with high-affinity and low-capacity solute carrier 6 (slc6) monoamine transporters for norepinephrine (net; norepinephrine transporter), dopamine (dat; dopamine transporter) and serotonin (sert; serotonin transporter). |
2021-12-10 |
2023-08-13 |
human |
| Ram Bishnoi, Marina C Badir, Sandarsh Surya, Nagy A Yousse. Predicting Neuropsychiatric Symptoms of Parkinson's Disease with Measures of Striatal Dopaminergic Deficiency. Current Alzheimer research. vol 18. issue 6. 2021-12-09. PMID:34455969. |
dopamine transporter (dat) imaging, a technique to measure the reduction in dopamine transporters is increasingly used as a tool in the diagnosis of pd. |
2021-12-09 |
2023-08-13 |
Not clear |
| Balestrino Roberta, Barone Paolo, Filippi Massimo, Erro Robert. Unexpected ( Journal of neurology. 2021-12-09. PMID:34537866. |
magnetic resonance imaging-mri, computerized tomography-ct) are used to exclude secondary syndromes, presynaptic dopaminergic imaging including imaging of dopamine transporter (dat)-can help the neurologist in the differential diagnosis between neurodegenerative parkinsonian syndromes and parkinsonism without dopamine deficiency. |
2021-12-09 |
2023-08-13 |
Not clear |
| Neha Thakur, Divyani Gupta, Debaprasad Mandal, Tharamani C Nagaia. Ultrasensitive electrochemical biosensors for dopamine and cholesterol: recent advances, challenges and strategies. Chemical communications (Cambridge, England). vol 57. issue 97. 2021-12-08. PMID:34811563. |
the level of da in the brain is modulated by the dopamine active transporter (dat), and is influenced by cholesterol levels in the lipid membrane environment. |
2021-12-08 |
2023-08-13 |
Not clear |
| Rebekka Schröder, Martin Reuter, Kaja Faßbender, Thomas Plieger, Jessie Poulsen, Simon S Y Lui, Raymond C K Chan, Ulrich Ettinge. The role of the SLC6A3 3' UTR VNTR in nicotine effects on cognitive, affective, and motor function. Psychopharmacology. 2021-12-04. PMID:34854936. |
a candidate polymorphism is the 40-base-pair variable number of tandem repeats polymorphism (rs28363170) in the slc6a3 gene coding for the dopamine transporter (dat). |
2021-12-04 |
2023-08-13 |
Not clear |
| Rebekka Schröder, Martin Reuter, Kaja Faßbender, Thomas Plieger, Jessie Poulsen, Simon S Y Lui, Raymond C K Chan, Ulrich Ettinge. The role of the SLC6A3 3' UTR VNTR in nicotine effects on cognitive, affective, and motor function. Psychopharmacology. 2021-12-04. PMID:34854936. |
the polymorphism has been associated with striatal dat availability (9r-carriers > 10r-homozygotes), and 9r-carriers have been shown to react more strongly to dopamine agonistic pharmacological challenges than 10r-homozygotes. |
2021-12-04 |
2023-08-13 |
Not clear |
| Sungwoo Bae, Hongyoon Choi, Wonseok Whi, Jin Chul Paeng, Gi Jeong Cheon, Keon Wook Kang, Dong Soo Le. Spatial Normalization Using Early-Phase [ Nuclear medicine and molecular imaging. vol 54. issue 6. 2021-12-03. PMID:33282002. |
spatial normalization using early-phase [ the precise quantification of dopamine transporter (dat) density on |
2021-12-03 |
2023-08-13 |
Not clear |
| Sharmistha Saha, Mahasweta Chatterjee, Sayanti Shom, Swagata Sinha, Kanchan Mukhopadhya. Functional SLC6A3 polymorphisms differentially affect autism spectrum disorder severity: a study on Indian subjects. Metabolic brain disease. 2021-11-30. PMID:34845656. |
level of da in the synaptic cleft is maintained by dopamine transporter (dat) and hence, to identify the role of dat in asd, we have analyzed four functional genetic variants, rs28363170, rs3836790, rs2652511, rs27072, in nuclear families with asd probands. |
2021-11-30 |
2023-08-13 |
human |
| Sara Simorgh, Rafieh Alizadeh, Ronk Shabani, Fariba Karimzadeh, Elham Seidkhani, Jamal Majidpoor, Fatemeh Moradi, Hamidreza Kasbiya. Olfactory mucosa stem cells delivery via nasal route: a simple way for the treatment of Parkinson disease. Neurotoxicity research. vol 39. issue 3. 2021-11-29. PMID:33433781. |
the results of real-time pcr and immunohistochemistry (ihc) analysis showed the expression of dopaminergic neuron markers such as pitx3, pax2, pax5 (as dopaminergic neurons markers), tyrosine hydroxylase (th), and dopamine transporter (dat) 2 months after ina of 1 × 10 |
2021-11-29 |
2023-08-13 |
rat |
| Dakota B Zinani, Hanna N Wetzel, Andrew B Norma. The compulsion zone explains the self-administration of cocaine, RTI-55 and bupropion in rats. Brain research. vol 1774. 2021-11-29. PMID:34736890. |
the inter-injection intervals of these dopamine transporter (dat) inhibitors were regular at a given unit dose and increased as a function of unit dose. |
2021-11-29 |
2023-08-13 |
rat |
| Jamie van Son, Katy A van Galen, Anne Marijn Bruijn, Karin E Koopman, Ruth I Versteeg, Susanne E la Fleur, Mireille J Serlie, Jan Booi. Striatal Dopamine Transporter Availability Is Not Associated with Food Craving in Lean and Obese Humans; a Molecular Imaging Study. Brain sciences. vol 11. issue 11. 2021-11-29. PMID:34827426. |
we used molecular neuroimaging to explore whether striatal dopamine transporter (dat) availability is associated with craving as measured with the general food craving questionnaire-trait (g-fcq-t). |
2021-11-29 |
2023-08-13 |
Not clear |
| Fei Zeng, Yan Fan, Russell W Brown, Wesley Drew Gill, Jennifer B Price, Thomas C Jones, Meng-Yang Zh. Effects of Manipulation of Noradrenergic Activities on the Expression of Dopaminergic Phenotypes in Aged Rat Brains. ASN neuro. vol 13. 2021-11-27. PMID:34812056. |
results showed that the administration of l-threo-3,4-dihydroxyphenylserine (l-dops) for 21 days significantly increased the expression of tyrosine hydroxylase (th) and dopamine transporter (dat) in the striatum and substantia nigra (sn) of 23-month-old rats. |
2021-11-27 |
2023-08-13 |
rat |
| Durairaj Ragu Varman, Lankupalle D Jayanthi, Sammanda Ramamoorth. Kappa Opioid Receptor Mediated Differential Regulation of Serotonin and Dopamine Transporters in Mood and Substance Use Disorder. Handbook of experimental pharmacology. vol 271. 2021-11-26. PMID:34136961. |
also, we discuss the recent findings on kor-mediated differential regulation of serotonin and dopamine transporters (sert and dat). |
2021-11-26 |
2023-08-13 |
Not clear |
| Hyun-Yeol Nam, Seongho Seo, Myung Jun Lee, Keunyoung Kim, In Joo Kim, Kyoungjune Pa. No association of Brain-derived neurotrophic factor with striatal dopamine transporter availability in healthy subjects. Nuklearmedizin. Nuclear medicine. vol 60. issue 6. 2021-11-26. PMID:34256395. |
we aimed to investigate the association of bdnf with dopamine transporter (dat) availabilities measured by positron emission tomography (pet) in healthy subjects. |
2021-11-26 |
2023-08-13 |
human |
| Hiroto Takahashi, Nobuo Kashiwagi, Atsuko Arisawa, Chisato Matsuo, Hiroki Kato, Hiroyoshi Adachi, Yuta Kajiyama, Hideki Mochizuki, Noriyuki Tomiyam. Imaging of the nigrostriatal system for evaluating the preclinical phase of Parkinson's disease development: the utility of neuromelanin, diffusion MRI, and DAT-SPECT. The British journal of radiology. 2021-11-26. PMID:34808066. |
to assess the utility of examining the nigrostriatal system with mri and dopamine transporter (dat) imaging for evaluating the preclinical phase of parkinson's disease (pd). |
2021-11-26 |
2023-08-13 |
Not clear |
| Seunghyeon Shin, Sungmin Jun, Hyun-Yeol Na. Effect of white matter hyperintensity on dopamine transporter availability of striatum measured by F-18 FP-CIT PET. Japanese journal of radiology. vol 39. issue 11. 2021-11-25. PMID:34142306. |
we aimed to evaluate the white matter hyperintensity (wmh) effect on dopamine transporter availability (dat) of striatum. |
2021-11-25 |
2023-08-13 |
Not clear |
| Daniel J Kramer, Erin E Aisenberg, Polina Kosillo, Drew Friedmann, David A Stafford, Angus Yiu-Fai Lee, Liqun Luo, Dirk Hockemeyer, John Ngai, Helen S Bateu. Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations. Cell reports. vol 35. issue 6. 2021-11-24. PMID:33979604. |
here, we establish a mouse line with flpo recombinase expressed from the endogenous slc6a3 (dopamine active transporter [dat]) locus. |
2021-11-24 |
2023-08-13 |
mouse |
| Dennis T Rogers, Francois Pomerleau, Zachary Kelley, Dustin Brown, Bert Lynn, Greg A Gerhardt, John Littleto. Target-directed evolution of novel modulators of the dopamine transporter in Lobelia cardinalis hairy root cultures. Journal of biotechnology. vol 342. 2021-11-23. PMID:34648893. |
the dopamine transporter (dat) is targeted in substance use disorders (suds), and "non-classical"" dat inhibitors with low abuse potential are therapeutic candidates. |
2021-11-23 |
2023-08-13 |
human |
| Peng-Ju Yan, Zhao-Xiang Ren, Zhi-Feng Shi, Chun-Lei Wan, Chao-Jun Han, Liu-Shuai Zhu, Ning-Ning Li, John L Waddington, Xue-Chu Zhe. Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice. Acta pharmacologica Sinica. 2021-11-23. PMID:34811513. |
it is generally accepted that meth exerts rewarding effects via competitive inhibition of the dopamine transporter (dat), but the molecular mechanism of meth addiction remains largely unknown. |
2021-11-23 |
2023-08-13 |
mouse |
| Yang Hyun Lee, Sangwon Lee, Seok Jong Chung, Han Soo Yoo, Jin Ho Jung, Kyoungwon Baik, Byoung Seok Ye, Young H Sohn, Mijin Yun, Phil Hyu Le. The pattern of FP-CIT PET in pure white matter hyperintensities-related vascular parkinsonism. Parkinsonism & related disorders. vol 82. 2021-11-22. PMID:33220520. |
to determine whether vascular parkinsonism (vap) patients with visually normal dopamine transporter (dat) scans have presynaptic dopaminergic depletion. |
2021-11-22 |
2023-08-13 |
Not clear |