| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyoungjune Pak, Seongho Seo, Myung Jun Lee, Hyung-Jun Im, Keunyoung Kim, In Joo Ki. Limited power of dopamine transporter mRNA mapping for predicting dopamine transporter availability. Synapse (New York, N.Y.). 2022-02-01. PMID:35104380. |
dopamine transporters (dat) are transmembrane proteins that translocate dopamine from the extracellular space into presynaptic neurons. |
2022-02-01 |
2023-08-13 |
Not clear |
| Kyoungjune Pak, Seongho Seo, Keunyoung Kim, Myung Jun Lee, In Joo Ki. SLC6A3 gene polymorphisms is associated with striatal dopamine transporter changes after glucose loading. Synapse (New York, N.Y.). 2022-01-31. PMID:35098587. |
we investigated the association between slc6a3 gene polymorphisms and changes in dopamine transporter (dat) availability after glucose loading in humans. |
2022-01-31 |
2023-08-13 |
Not clear |
| Renata Faro Guerra, Ilza Rosa Batista, Hyoun S Kim, Marcelo Queiroz Hoexter, Ming Chi Shih, Rodrigo Affonseca Bressan, Hermano Tavare. Neuroimaging of Dopamine Transporter Density in the Striatum of Disordered Gamblers. Journal of gambling studies. 2022-01-31. PMID:35099670. |
the aim of the present research was to add to the growing literature on dopamine and gambling disorder (gd) by assessing whether gd is associated with dopamine transporter (dat) density in the ventral striatum compared to healthy controls and whether dat density was associated with key characteristics of gd (e.g., abstinence, craving). |
2022-01-31 |
2023-08-13 |
Not clear |
| Tomoyuki Miyamoto, Yasuhisa Akaiwa, Kyoko Numahata, Kenta Yoshizawa, Toshimi Sairenchi, Masayuki Miyamot. Striatal dopamine transporter degeneration in right-handed REM sleep behavior disorder patients progresses faster in the left hemisphere. Parkinsonism & related disorders. vol 95. 2022-01-30. PMID:35093712. |
in right-handed patients with idiopathic rapid eye movement sleep behavior disorder (irbd) or parkinson's disease (pd), dopamine transporter (dat) single-photon emission computed tomography (spect) shows a predominant nigrostriatal deficit in the left striatum. |
2022-01-30 |
2023-08-13 |
Not clear |
| Skye Hsin-Hsien Yeh, Chi-Jung Tsai, Tsung-Hsun Yu, Yung-Hsiao Chiang, Shinn-Zong Lin, Nan-Jing Peng, Wen-Sheng Huan. 99mTc-TRODAT-1 SPECT Revealed That Striatal Dopamine Transport Availability Significantly Decreases in Late Mid-Aged Healthy Taiwanese and Then Remains Stable. Clinical nuclear medicine. 2022-01-26. PMID:35081059. |
neuroimaging studies in the past 20 years have documented an age-related decline in striatal dopamine transporters (dats), which is a marker of dopaminergic neurodegeneration; however, concerns about ethnic variations in the decline in dat with age have not been addressed. |
2022-01-26 |
2023-08-13 |
Not clear |
| Concepció Marin, Mireya Fuentes, Isam Alobid, Valeria Tubita, María Jesús Rojas-Lechuga, Joaquim Mullo. Olfactory Bulb Excitotoxicity as a Gap-Filling Mechanism Underlying the Link Between Traumatic Brain Injury-Induced Secondary Neuronal Degeneration and Parkinson's Disease-Like Pathology. Neurochemical research. 2022-01-24. PMID:35067829. |
we examined the number of nigral dopaminergic neurons (th +), nigral α-synuclein expression, the striatal dopamine transporter (dat) expression, and motor performance after bilateral ob n-methyl-d-aspartate (nmda)-induced excitotoxic lesions in rodents. |
2022-01-24 |
2023-08-13 |
Not clear |
| Chenhao Jia, Meiqi Wu, Tzu-Chen Yen, Yanfeng Li, Ruixue Cu. Complementary Utility of Dopamine Transporter and Tau PET Imaging in the Diagnosis of Progressive Supranuclear Palsy: A Case Report. Clinical nuclear medicine. 2022-01-12. PMID:35020665. |
brain 18f-fdg pet/ct was unable to distinguish among apss (atypical parkinsonian syndromes); pet investigations of dopamine transporter (dat) function (11c-cft) and tau pathology (18f-apn-1607) were performed. |
2022-01-12 |
2023-08-13 |
Not clear |
| Phillip M Mackie, Adithya Gopinath, Dominic M Montas, Alyssa Nielsen, Aidan Smith, Rachel A Nolan, Kaitlyn Runner, Stephanie M Matt, John McNamee, Joshua E Riklan, Kengo Adachi, Andria Doty, Adolfo Ramirez-Zamora, Long Yan, Peter J Gaskill, Wolfgang J Streit, Michael S Okun, Habibeh Khoshboue. Functional characterization of the biogenic amine transporters on human macrophages. JCI insight. 2022-01-11. PMID:35015729. |
to address these knowledge gaps, we investigated the function of norepinephrine (net) and dopamine (dat) transporters on human monocyte-derived macrophages. |
2022-01-11 |
2023-08-13 |
human |
| Phillip M Mackie, Adithya Gopinath, Dominic M Montas, Alyssa Nielsen, Aidan Smith, Rachel A Nolan, Kaitlyn Runner, Stephanie M Matt, John McNamee, Joshua E Riklan, Kengo Adachi, Andria Doty, Adolfo Ramirez-Zamora, Long Yan, Peter J Gaskill, Wolfgang J Streit, Michael S Okun, Habibeh Khoshboue. Functional characterization of the biogenic amine transporters on human macrophages. JCI insight. 2022-01-11. PMID:35015729. |
lps induced reverse transport of dopamine through dat, engaging an autocrine/paracrine signaling loop that regulated the macrophage response. |
2022-01-11 |
2023-08-13 |
human |
| Md Ashraf-Uz-Zaman, Guangchen Ji, Dalton Tidwell, Linda Yin, Smathorn Thakolwiboon, Jie Pan, Riley Junell, Zach Griffin, Sadisna Shahi, Derek Barthels, Md Sanaullah Sajib, Paul C Trippier, Constantinos M Mikelis, Hiranmoy Das, Mirla Avila, Volker Neugebauer, Nadezhda A Germa. Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. ACS chemical neuroscience. 2022-01-03. PMID:34978174. |
we have recently reported a new class of dopamine transporter (dat) inhibitors with high selectivity to the dat over other g-protein coupled receptors tested. |
2022-01-03 |
2023-08-13 |
Not clear |
| Tiziana Romanazzi, Daniele Zanella, Mary Hongying Cheng, Behrgen Smith, Angela M Carter, Aurelio Galli, Ivet Bahar, Elena Boss. Bile Acids Gate Dopamine Transporter Mediated Currents. Frontiers in chemistry. vol 9. 2021-12-27. PMID:34957043. |
sterols such as cholesterol interact with monoamine transporters, including the dopamine (da) transporter (dat) which plays a key role in da neurotransmission and reward. |
2021-12-27 |
2023-08-13 |
Not clear |
| Ana Virel, Jarkko Johansson, Jan Axelsson, Madelene Ericsson, Rutger Laterveer, Mattias Ögren, Greger Orädd, Susanna Jakobson Mo, Sara Af Bjerké. N-acetylcysteine decreases dopamine transporter availability in the non-lesioned striatum of the 6-OHDA hemiparkinsonian rat. Neuroscience letters. 2021-12-27. PMID:34958912. |
the short- and long-term regulatory mechanisms of nac on the 6-ohda hemiparkinsonian rat model were longitudinally investigated by performing positron emission tomography (pet) imaging using the specific dopamine transporter (dat) radioligand [ |
2021-12-27 |
2023-08-13 |
rat |
| Don Gueu Park, Suk Yun Kang, Jin Yong Hong, Mun Kyung Sunwoo, Jung Han Yoo. Factors associated with motor severity in vascular parkinsonism with normal dopamine transporter imaging. Parkinsonism & related disorders. vol 94. 2021-12-15. PMID:34906916. |
to delineate the determinants of motor severity in vascular parkinsonism (vap), we investigated the impact of regional white matter intensity (wmh) burden and co-morbidities on the motor score in the patients with vap and normal dopamine transporter (dat) imaging. |
2021-12-15 |
2023-08-13 |
Not clear |
| Osama Refai, Shaili Aggarwal, Mary Hongying Cheng, Zayna Gichi, Joseph M Salvino, Ivet Bahar, Randy D Blakely, Ole V Mortense. Allosteric Modulator KM822 Attenuates Behavioral Actions of Amphetamine in C. elegans through Interactions with the Dopamine Transporter DAT-1. Molecular pharmacology. 2021-12-15. PMID:34906999. |
aberrant dopamine (da) signaling is associated with several psychiatric disorders such as bipolar disorder, addiction, and parkinson's disease, and several medications that target the da transporter (dat) can induce or treat these disorders. |
2021-12-15 |
2023-08-13 |
human |
| Susanna Jakobson Mo, Jan Axelsson, Lars J Stiernman, Anne Larsson, Sara Af Bjerkén, David Bäckström, Therese Gabrielsson Kellgren, Andrea Varrone, Katrine Riklun. VNTR polymorphism in the SLC6A3 gene does not influence dopamine transporter availability measured by [18F]FE-PE2I PET or [123I]FP-Cit SPECT. Nuclear medicine communications. 2021-12-15. PMID:34908018. |
to investigate the potential impact of polymorphism in the 3'-untranslated region (3'utr) of the slc6a3 gene (dat1) on normal variation in dopamine transporter (dat) imaging with [18f]fe-pe2i pet and [123i]fp-cit spect. |
2021-12-15 |
2023-08-13 |
Not clear |
| Thomas Brücke, Christof Brück. Dopamine transporter (DAT) imaging in Parkinson's disease and related disorders. Journal of neural transmission (Vienna, Austria : 1996). 2021-12-15. PMID:34910248. |
dopamine transporter (dat) imaging in parkinson's disease and related disorders. |
2021-12-15 |
2023-08-13 |
Not clear |
| Thomas Brücke, Christof Brück. Dopamine transporter (DAT) imaging in Parkinson's disease and related disorders. Journal of neural transmission (Vienna, Austria : 1996). 2021-12-15. PMID:34910248. |
this review gives an insight into the beginnings of dopamine transporter (dat) imaging in the early 1990s, focussing on single photon emission tomography (spect). |
2021-12-15 |
2023-08-13 |
Not clear |
| Panagiotis Perdikaris, Catherine R Dermo. Behavioral and neurochemical profile of MK-801 adult zebrafish model: Forebrain β Progress in neuro-psychopharmacology & biological psychiatry. 2021-12-13. PMID:34896197. |
mk-801-treated zebrafish showed increased telencephalic protein expression of metabotropic glutamate 5 receptor (mglur5), dopamine transporter (dat) and β |
2021-12-13 |
2023-08-13 |
zebrafish |
| Gunnar Sørensen, Mattias Rickhag, Damiana Leo, Matthew D Lycas, Pernille Herrstedt Ridderstrøm, Pia Weikop, Jamila H Lilja, Pedro Rifes, Freja Herborg, David Woldbye, Gitta Wörtwein, Raul R Gainetdinov, Anders Fink-Jensen, Ulrik Gethe. Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation. The Journal of biological chemistry. vol 297. issue 6. 2021-12-11. PMID:34756883. |
the dopamine (da) transporter (dat) is part of a presynaptic multiprotein network involving interactions with scaffold proteins via its c-terminal pdz domain-binding sequence. |
2021-12-11 |
2023-08-13 |
mouse |
| Michelle A Sahai, Jolanta Opacka-Juffr. Molecular mechanisms of action of stimulant novel psychoactive substances that target the high-affinity transporter for dopamine. Neuronal signaling. vol 5. issue 4. 2021-12-11. PMID:34888062. |
the main biological target of stimulants, both classical and nps, is the dopamine transporter (dat) implicated in the dopamine-enhancing effects of these drugs. |
2021-12-11 |
2023-08-13 |
human |