| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rajani Maiya, Kari J Buck, R Adron Harris, R Dayne Mayfiel. Ethanol-sensitive sites on the human dopamine transporter. The Journal of biological chemistry. vol 277. issue 34. 2002-09-23. PMID:12070173. |
previous studies have shown that ethanol enhanced [(3)h]dopamine uptake in xenopus oocytes expressing the dopamine transporter (dat). |
2002-09-23 |
2023-08-12 |
human |
| Bruce E Blough, Kathryn I Keverline, Zhe Nie, Hernán Navarro, Michael J Kuhar, F Ivy Carrol. Synthesis and transporter binding properties of 3beta-[4'-(phenylalkyl, -phenylalkenyl, and -phenylalkynyl)phenyl]tropane-2beta-carboxylic acid methyl esters: evidence of a remote phenyl binding domain on the dopamine transporter. Journal of medicinal chemistry. vol 45. issue 18. 2002-09-23. PMID:12190324. |
a series of 4'-substituted 3beta-phenyltropane-2beta-carboxylic acid methyl esters were synthesized and evaluated for binding at the dopamine transporter (dat) in order to better define the pharmacophore for the cocaine binding site on the dat. |
2002-09-23 |
2023-08-12 |
Not clear |
| Joanna Hauser, Paweł Kapelski, Piotr M Czerski, Sebastian Godlewski, Monika Dmitrzak-Weglarz, Katarzyna Twardowska, Janusz K Rybakowsk. [Lack of association between VNTR polymorphism of DAT gene and schizophrenia]. Psychiatria polska. vol 36. issue 3. 2002-09-20. PMID:12149916. |
in the present work the results of an association study of vntr polymorphism of dopamine transporter gene (dat) in schizophrenia are presented. |
2002-09-20 |
2023-08-12 |
Not clear |
| Virginia M Pickel, Miguel Garzón, Elisa Mengua. Electron microscopic immunolabeling of transporters and receptors identifies transmitter-specific functional sites envisioned in Cajal's neuron. Progress in brain research. vol 136. 2002-09-19. PMID:12143378. |
dopamine terminals in the striatum and ventral pallidum, as well as dendrites of midbrain dopaminergic neurons in the ventral tegmental area and substantia nigra express the plasmalemmal dopamine transporter (dat) and the vesicular monoamine transporter (vmat2). |
2002-09-19 |
2023-08-12 |
Not clear |
| Dennis K Miller, Sangeetha P Sumithran, Linda P Dwoski. Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183670. |
bupropion, an efficacious antidepressant and smoking cessation agent, inhibits dopamine and norepinephrine transporters (dat and net, respectively). |
2002-09-18 |
2023-08-12 |
rat |
| Jilla Sabeti, Greg A Gerhardt, Nancy R Zahnise. Acute cocaine differentially alters accumbens and striatal dopamine clearance in low and high cocaine locomotor responders: behavioral and electrochemical recordings in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183681. |
the role of the dopamine transporter (dat) in mediating the behavioral differences in cocaine responsiveness in lcrs and hcrs was investigated by high-speed chronoamperometric recording of exogenous dopamine (da) clearance signals in nucleus accumbens (nac) and dorsal striatum (dstr). |
2002-09-18 |
2023-08-12 |
rat |
| K Lemmer, G Ahnert-Hilger, M Höpfner, S Hoegerle, S Faiss, P Grabowski, M Jockers-Scherübl, E O Riecken, M Zeitz, H Scherüb. Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells. Life sciences. vol 71. issue 6. 2002-09-17. PMID:12072155. |
to further characterize the dopaminergic system in neuroendocrine gastrointestinal tumor cells, we investigated the expression of both dopamine receptors and the transmembrane dopamine transporter (dat) in the human neuroendocrine pancreatic cell line bon and in the neuroendocrine gut cell line stc-1. |
2002-09-17 |
2023-08-12 |
human |
| K Lemmer, G Ahnert-Hilger, M Höpfner, S Hoegerle, S Faiss, P Grabowski, M Jockers-Scherübl, E O Riecken, M Zeitz, H Scherüb. Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells. Life sciences. vol 71. issue 6. 2002-09-17. PMID:12072155. |
both bon and stc-1 cells expressed mrna of the dopamine receptors d2-d5 and dat. |
2002-09-17 |
2023-08-12 |
human |
| K Lemmer, G Ahnert-Hilger, M Höpfner, S Hoegerle, S Faiss, P Grabowski, M Jockers-Scherübl, E O Riecken, M Zeitz, H Scherüb. Expression of dopamine receptors and transporter in neuroendocrine gastrointestinal tumor cells. Life sciences. vol 71. issue 6. 2002-09-17. PMID:12072155. |
the presence of both dopamine receptors and of the dat suggests an autocrine and/or paracrine function of dopamine in neuroendocrine gastrointestinal tumor cells. |
2002-09-17 |
2023-08-12 |
human |
| Kristine Norgaard-Nielsen, Lene Norregaard, Hanne Hastrup, Jonathan A Javitch, Ulrik Gethe. Zn(2+) site engineering at the oligomeric interface of the dopamine transporter. FEBS letters. vol 524. issue 1-3. 2002-09-13. PMID:12135746. |
here we demonstrate the engineering of a zn(2+) binding site at the predicted dimeric interface of the dopamine transporter (dat) corresponding to the external end of transmembrane segment 6. |
2002-09-13 |
2023-08-12 |
Not clear |
| Kristine Norgaard-Nielsen, Lene Norregaard, Hanne Hastrup, Jonathan A Javitch, Ulrik Gethe. Zn(2+) site engineering at the oligomeric interface of the dopamine transporter. FEBS letters. vol 524. issue 1-3. 2002-09-13. PMID:12135746. |
upon binding to this site, which involves a histidine inserted in position 310 (v310h) and the endogenous cys306 within the same dat molecule, zn(2+) potently inhibits [(3)h]dopamine uptake. |
2002-09-13 |
2023-08-12 |
Not clear |
| Vera Lehmensiek, Eva-Maria Tan, Johannes Schwarz, Alexander Storc. Expression of mutant alpha-synucleins enhances dopamine transporter-mediated MPP+ toxicity in vitro. Neuroreport. vol 13. issue 10. 2002-09-13. PMID:12151787. |
here we report on effects of mutant alpha-synucleins on dopamine transporter (dat)-mediated toxicity of the selective dopaminergic neurotoxin 1-methyl-4-phenylpyridinium ion (mpp+) in vitro. |
2002-09-13 |
2023-08-12 |
human |
| Xiaoqing Xi, Renyuan Chu, Xingtao Zhou, Yi Lu, Xingdang Li. Retinal dopamine transporter in experimental myopia. Chinese medical journal. vol 115. issue 7. 2002-09-10. PMID:12150736. |
to investigate the distribution, changes and a possible role for retinal dopamine transporter (dat) in experimental myopia in chickens. |
2002-09-10 |
2023-08-12 |
Not clear |
| Ana M Carneiro, Susan L Ingram, Jean-Martin Beaulieu, Ava Sweeney, Susan G Amara, Sheila M Thomas, Marc G Caron, Gonzalo E Torre. The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177201. |
the na+/cl--dependent dopamine transporter (dat) is critical in terminating dopaminergic transmission by removing the transmitter away from the synapse. |
2002-09-04 |
2023-08-12 |
human |
| G Ransmayr, K Seppi, E Donnemiller, E Luginger, J Marksteiner, G Riccabona, W Poewe, G K Wennin. Striatal dopamine transporter function in dementia with Lewy bodies and Parkinson's disease. European journal of nuclear medicine. vol 28. issue 10. 2002-08-26. PMID:11685496. |
the aim of this study was to compare parkinsonian features and loss of striatal dopamine transporter (dat) function in patients with dementia with lewy bodies (dlb) and parkinson's disease (pd), matched for age and disease duration. |
2002-08-26 |
2023-08-12 |
Not clear |
| J J Hwang, M H Liao, T C Yen, S P Wey, K J Lin, W H T Pan, J C Chen, G Tin. Biodistribution study of [99mTc] TRODAT-1 alone or combined with other dopaminergic drugs in mice with macroautoradiography. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. vol 57. issue 1. 2002-08-19. PMID:12137024. |
a 99mtc labeled tropane derivative, [99mtc] trodat-1 (2beta-((n,n'-bis(2-mercaptoethyl) ethylene diamino)methyl), 3beta-(4-chlorophenyl) tropane), is a potential dopamine transporter (dat) imaging agent for the central nervous system. |
2002-08-19 |
2023-08-12 |
mouse |
| Taleen Hanania, Nancy R Zahnise. Locomotor activity induced by noncompetitive NMDA receptor antagonists versus dopamine transporter inhibitors: opposite strain differences in inbred long-sleep and short-sleep mice. Alcoholism, clinical and experimental research. vol 26. issue 4. 2002-08-16. PMID:11981117. |
thus, in this study, we sought to determine whether: (1) habituation to the behavioral environment alters the differential locomotor-stimulant effects of noncompetitive nmdar antagonists in ils and iss mice and (2) the differential behavioral sensitivity of ils and iss mice to noncompetitive nmdar antagonists is mediated through direct inhibition of the dopamine transporter (dat). |
2002-08-16 |
2023-08-12 |
mouse |
| Stéphanie Barc, Guylène Page, Laurence Barrier, François Huguet, Bernard Fauconnea. Progressive alteration of neuronal dopamine transporter activity in a rat injured by an intranigral injection of MPP+. Brain research. vol 941. issue 1-2. 2002-08-14. PMID:12031549. |
the present study describes the effects of intranigral mpp+ administration either at 10 or 40 microg on the neuronal dopamine transporter (dat) activity measured in rat striatal synaptosomes at different times after lesion. |
2002-08-14 |
2023-08-12 |
rat |
| J Wang, Z Liu, B Che. [Association between genetic polymorphism of dopamine transporter gene and susceptibility to Parkinson's disease]. Zhonghua yi xue za zhi. vol 80. issue 5. 2002-08-13. PMID:11798784. |
to explore the association between genetic polymorphism of dopamine transporter (dat) gene and susceptibility to parkinson's disease (pd). |
2002-08-13 |
2023-08-12 |
Not clear |
| Y Ma, V Dhawan, M Mentis, T Chaly, P G Spetsieris, D Eidelber. Parametric mapping of [18F]FPCIT binding in early stage Parkinson's disease: a PET study. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112405. |
we have shown that fluorinated n-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane ([(18)f]fpcit) and pet offer a valuable means of quantifying regional abnormality in dopamine transporter (dat) imaging associated with parkinson's disease (pd). |
2002-08-08 |
2023-08-12 |
human |