| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jason R Richardson, Gary W Mille. Acute exposure to aroclor 1016 or 1260 differentially affects dopamine transporter and vesicular monoamine transporter 2 levels. Toxicology letters. vol 148. issue 1-2. 2004-04-02. PMID:15019086. |
dopamine transporter (dat) levels were decreased at all time points in aroclor 1016 treated animals, and on days 1 and 7 in aroclor 1260 treated animals. |
2004-04-02 |
2023-08-12 |
Not clear |
| Jason R Richardson, Gary W Mille. Acute exposure to aroclor 1016 or 1260 differentially affects dopamine transporter and vesicular monoamine transporter 2 levels. Toxicology letters. vol 148. issue 1-2. 2004-04-02. PMID:15019086. |
these data suggest that pcb-induced reductions in striatal dopamine may be mediated by alterations in dat and vmat2 expression. |
2004-04-02 |
2023-08-12 |
Not clear |
| Paola P Piccin. Dopamine transporter: basic aspects and neuroimaging. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531039. |
the plasma membrane dopamine transporter (dat) is found exclusively in dopamine neurones and seems to be the defining molecule of the dopamine neurone. |
2004-03-29 |
2023-08-12 |
Not clear |
| Werner Poewe, Christoph Scherfle. Role of dopamine transporter imaging in investigation of parkinsonian syndromes in routine clinical practice. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531041. |
we discuss the potential role of dopamine transporter (dat) imaging by single photon emission computed tomography (spect) as a biological marker for differentiating among parkinsonian disorders in routine clinical practice, and the implication for disease progression assessment is considered. |
2004-03-29 |
2023-08-12 |
Not clear |
| Vicky Marshall, Donald G Grosse. Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531042. |
dopamine transporter (dat) imaging detects presynaptic dopamine neuronal dysfunction and thereby assists differentiation of conditions with and without dopamine deficit. |
2004-03-29 |
2023-08-12 |
Not clear |
| Vicky Marshall, Donald G Grosse. Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531042. |
in atypical tremor disorders, dat imaging can differentiate between parkinson's disease (pd), where dopamine deficit is demonstrated on dat imaging, and essential tremor, where no dopamine deficit is found. |
2004-03-29 |
2023-08-12 |
Not clear |
| Walter Pirke. Correlation of dopamine transporter imaging with parkinsonian motor handicap: how close is it? Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531046. |
during the past decade, dopamine transporter (dat) imaging with single photon emission computerized tomography (spect) or positron emission tomography (pet) has evolved as an objective in vivo marker of nigrostriatal neuron loss in parkinson's disease (pd). |
2004-03-29 |
2023-08-12 |
Not clear |
| Paul K Morris. How valid is dopamine transporter imaging as a surrogate marker in research trials in Parkinson's disease? Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531048. |
data from the available dopamine transporter (dat) positron emission tomography (pet) and single photon emission computed tomography (spect) studies are examined for these three key factors. |
2004-03-29 |
2023-08-12 |
Not clear |
| George R Uh. Dopamine transporter: basic science and human variation of a key molecule for dopaminergic function, locomotion, and parkinsonism. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531049. |
we review the basic science of the dopamine transporter (dat), a key neurotransmitter for locomotor control and reward systems, including those lost or deranged in parkinson's disease (pd). |
2004-03-29 |
2023-08-12 |
human |
| Elisa Mengual, Virginia M Picke. Regional and subcellular compartmentation of the dopamine transporter and tyrosine hydroxylase in the rat ventral pallidum. The Journal of comparative neurology. vol 468. issue 3. 2004-03-26. PMID:14681933. |
the vp catecholaminergic innervation is derived from midbrain dopaminergic neurons that differ in expression levels of the dopamine transporter (dat) and from brainstem noradrenergic neurons without dat. |
2004-03-26 |
2023-08-12 |
rat |
| Jon D Gaffaney, Roxanne A Vaugha. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Molecular pharmacology. vol 65. issue 3. 2004-03-23. PMID:14978248. |
changes in protease sensitivity of extracellular loop two (el2) of the dopamine transporter (dat) during inhibitor and substrate binding were examined using trypsin proteolysis and epitope-specific immunoblotting. |
2004-03-23 |
2023-08-12 |
rat |
| Jon D Gaffaney, Roxanne A Vaugha. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Molecular pharmacology. vol 65. issue 3. 2004-03-23. PMID:14978248. |
to assess the effects of el2 proteolysis on dat function, the binding and transport properties of trypsin-digested dat were assayed with [3h]cft and [3h]dopamine. |
2004-03-23 |
2023-08-12 |
rat |
| B Corriga. Attention deficit hyperactivity disorder in sport: a review. International journal of sports medicine. vol 24. issue 7. 2004-03-19. PMID:12968213. |
the dopamine transporter (dat) regulates dopamine by removing excess. |
2004-03-19 |
2023-08-12 |
human |
| B Corriga. Attention deficit hyperactivity disorder in sport: a review. International journal of sports medicine. vol 24. issue 7. 2004-03-19. PMID:12968213. |
the dopamine agonist methylphenidate blockades dat, significantly increasing extra cellular dopamine, so correcting the dopamine deficiency. |
2004-03-19 |
2023-08-12 |
human |
| Michael F Salvatore, Subbu Apparsundaram, Greg A Gerhard. Decreased plasma membrane expression of striatal dopamine transporter in aging. Neurobiology of aging. vol 24. issue 8. 2004-03-11. PMID:14643386. |
aging in rodents, monkeys, and man is correlated with a reduction in dopamine transporter (dat) ligand binding and dat function. |
2004-03-11 |
2023-08-12 |
rat |
| M Lonjon, M H Quentien, J J Risso, J F Michiels, E Carre, J C Rostain, O Darbi. Alteration of striatal dopaminergic function induced by glioma development: a microdialysis and immunohistological study in the rat striatum. Neuroscience letters. vol 354. issue 2. 2004-03-11. PMID:14698456. |
immunohistochemistry was performed to investigate changes in neurofilament (nf), tyrosine hydroxylase (th) and dopamine transporter (dat) expression. |
2004-03-11 |
2023-08-12 |
rat |
| Anna M S Kindlundh, Sadia Rahman, Jonas Lindblom, Fred Nyber. Increased dopamine transporter density in the male rat brain following chronic nandrolone decanoate administration. Neuroscience letters. vol 356. issue 2. 2004-03-10. PMID:14746881. |
recently chronic administration with nandrolone decanoate to male rats has been shown to increase the dopamine transporter (dat) density in the striatum visualised in vivo by positron emission tomography. |
2004-03-10 |
2023-08-12 |
rat |
| Wassilios Meissner, Caroline Prunier, Denis Guilloteau, Sylvie Chalon, Christian E Gross, Erwan Bezar. Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease. Molecular neurobiology. vol 28. issue 3. 2004-03-09. PMID:14709785. |
striatal dopamine transporter (dat) binding and dopamine (da) content decreased to 19.7 +/- 4.9% and 18.2 +/- 5.6% of untreated monkeys. |
2004-03-09 |
2023-08-12 |
human |
| Ki-Hwan Lee, Young-Don Kwak, Dong-Hwan Kim, Mi-Yoon Chang, Young-Seek Lee, Yong-Sung Le. Human zinc finger protein 161, a novel transcriptional activator of the dopamine transporter. Biochemical and biophysical research communications. vol 313. issue 4. 2004-03-05. PMID:14706637. |
the dopamine transporter (dat) terminates dopaminergic neurotransmission via reuptake of released dopamine into presynaptic neurons. |
2004-03-05 |
2023-08-12 |
human |
| T R Guilarte, M K Nihei, J L McGlothan, A S Howar. Methamphetamine-induced deficits of brain monoaminergic neuronal markers: distal axotomy or neuronal plasticity. Neuroscience. vol 122. issue 2. 2004-03-01. PMID:14614914. |
our findings indicate that the loss of dopamine transporters (dat), serotonin transporters (5-htt), vesicular monoamine transporter type-2 (vmat-2) and glial cell activation induced by meth in the striatum and in the central gray are consistent with a degenerative process. |
2004-03-01 |
2023-08-12 |
rat |