| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Marazziti, Silvia Mandillo, Chiara Di Pietro, Elisabetta Golini, Rafaele Matteoni, Glauco P Tocchini-Valentin. GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 23. 2008-01-22. PMID:17519329. |
we report here that gpr37 interacts with the dopamine transporter (dat) and modulates dat activity. |
2008-01-22 |
2023-08-12 |
mouse |
| Daniela Marazziti, Silvia Mandillo, Chiara Di Pietro, Elisabetta Golini, Rafaele Matteoni, Glauco P Tocchini-Valentin. GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 23. 2008-01-22. PMID:17519329. |
gpr37-null mutant mice showed enhanced dat-mediated dopamine uptake in striatal membrane samples, with a significant increase in the number of plasma membrane dat molecules. |
2008-01-22 |
2023-08-12 |
mouse |
| Ji-Hoon Yoo, Yun-Sun Nam, Seok-Yong Lee, Choon-Gon Jan. Dopamine neurotransmission is involved in the attenuating effects of 5-HT3 receptor antagonist MDL 72222 on acute methamphetamine-induced locomotor hyperactivity in mice. Synapse (New York, N.Y.). vol 62. issue 1. 2008-01-22. PMID:17948891. |
for this, we examined alterations of dopamine (da) in the form of d1 receptor, d2 receptor, and dopamine transporter (dat) binding labeled with [3h]sch23390 for d1, [3h]raclopride for d2, and [3h]mazindol for dat binding in the mouse brains with acute map exposure or pretreatment of mdl 72222 with map. |
2008-01-22 |
2023-08-12 |
mouse |
| Noelia Granado, Isabel Escobedo, Esther O'Shea, Isabel Colado, Rosario Moratall. Early loss of dopaminergic terminals in striosomes after MDMA administration to mice. Synapse (New York, N.Y.). vol 62. issue 1. 2008-01-22. PMID:17960765. |
in this study we examined the long-term effect induced by mdma on tyrosine hydroxylase (th) and dopamine transporter (dat) immunoreactivity in the striosomes and matrix compartments of mouse striatum. |
2008-01-22 |
2023-08-12 |
mouse |
| Benjamin B Gelman, Jeffrey A Spencer, Charles E Holzer, Vicki M Souku. Abnormal striatal dopaminergic synapses in National NeuroAIDS Tissue Consortium subjects with HIV encephalitis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 1. issue 4. 2008-01-17. PMID:18040813. |
the presynaptic dopamine reuptake transporter (dat) was increased reciprocally. |
2008-01-17 |
2023-08-12 |
human |
| Yohtaro Numachi, Arihisa Ohara, Motoyasu Yamashita, Setsu Fukushima, Hideaki Kobayashi, Harumi Hata, Hidekazu Watanabe, F Scott Hall, Klaus-Peter Lesch, Dennis L Murphy, George R Uhl, Ichiro Sor. Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. European journal of pharmacology. vol 572. issue 2-3. 2008-01-14. PMID:17673199. |
we examined the hyperthermic and lethal toxic effects of methamphetamine in dopamine transporter (dat) and/or serotonin transporter (sert) knockout (ko) mice. |
2008-01-14 |
2023-08-12 |
mouse |
| Thomas J Spencer, Joseph Biederman, Bertha K Madras, Darin D Dougherty, Ali A Bonab, Elijahu Livni, Peter C Meltzer, Jessica Martin, Scott Rauch, Alan J Fischma. Further evidence of dopamine transporter dysregulation in ADHD: a controlled PET imaging study using altropane. Biological psychiatry. vol 62. issue 9. 2008-01-09. PMID:17511972. |
the dopamine transporter (dat) is known to be a key regulator of dopamine, and recent studies of genetics, treatment, and imaging have highlighted the role of dat in attention-deficit/hyperactivity disorder (adhd). |
2008-01-09 |
2023-08-12 |
Not clear |
| Mehrzad Cohenpour, Haim Gola. [Nuclear neuroimaging of dopamine transporter in Parkinsonism--role in routine clinical practice]. Harefuah. vol 146. issue 9. 2008-01-07. PMID:17969308. |
brain spect imaging of the dopamine transporter (dat) with specific radioligands is a sensitive method for examining the integrity of the presynaptic dopaminergic system. |
2008-01-07 |
2023-08-12 |
Not clear |
| Nicolaas I Bohnen, Hiroto Kuwabara, Gregory M Constantine, Chester A Mathis, Robert Y Moor. Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease. Neuroscience letters. vol 424. issue 3. 2008-01-04. PMID:17714864. |
pd patients (n=28) underwent [11c]beta-cft dopamine transporter (dat) positron emission tomography (pet) and grooved pegboard testing. |
2008-01-04 |
2023-08-12 |
Not clear |
| Xiaoqin Huang, Chang-Guo Zha. How dopamine transporter interacts with dopamine: insights from molecular modeling and simulation. Biophysical journal. vol 93. issue 10. 2008-01-02. PMID:17704152. |
the modeled 3d structures provide some detailed structural and mechanistic insights concerning how dopamine transporter (dat) interacts with dopamine at atomic level, extending our mechanistic understanding of the dopamine reuptake with the help of na(+) ions. |
2008-01-02 |
2023-08-12 |
Not clear |
| Xiaoqin Huang, Chang-Guo Zha. How dopamine transporter interacts with dopamine: insights from molecular modeling and simulation. Biophysical journal. vol 93. issue 10. 2008-01-02. PMID:17704152. |
based on the modeled structures, our calculated binding free energy (deltag(bind) = -6.4 kcal/mol) for dopamine binding with dat is also reasonably close to the experimentally derived deltag(bind) value of -7.4 kcal/mol. |
2008-01-02 |
2023-08-12 |
Not clear |
| Vesna Sossi, Raúl de la Fuente-Fernández, Michael Schulzer, Andre R Troiano, Thomas J Ruth, A Jon Stoess. Dopamine transporter relation to dopamine turnover in Parkinson's disease: a positron emission tomography study. Annals of neurology. vol 62. issue 5. 2007-12-27. PMID:17886297. |
to investigate the role of the dopamine transporter (dat) in the regulation of synaptic dopamine (da) levels in parkinson's disease and its role in the preservation of da in presynaptic terminals. |
2007-12-27 |
2023-08-12 |
Not clear |
| Jun Yang, Qingshan Teng, Mary E Garrity-Moses, Shearwood McClelland, Thais Federici, Erin Carlton, Jonathon Riley, Nicholas M Bouli. Reversible unilateral nigrostriatal pathway inhibition induced through expression of adenovirus-mediated clostridial light chain gene in the substantia nigra. Neuromolecular medicine. vol 9. issue 3. 2007-12-27. PMID:17914186. |
tyrosine hydroxylase (th) and dopamine transporter (dat) immunohistochemistry (ihc) showed markedly decreased staining in ipsilateral sn and striatum in 6-ohda but not adlc or adgfp rats. |
2007-12-27 |
2023-08-12 |
rat |
| Monika Cs Horvath, Gabor G Kovacs, Viktor Kovari, Katalin Majtenyi, Yasmin L Hurd, Eva Kelle. Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 49. 2007-12-27. PMID:18057194. |
we examined mrna expression levels of da transporter (dat), tyrosine hydroxylase (th), dopamine d2 receptor, alpha-synuclein, and nuclear receptor-related 1 (nurr1) in discrete mesocorticolimbic and nigrostriatal subpopulations of heroin users and control subjects. |
2007-12-27 |
2023-08-12 |
human |
| Gang Zhao, Sheng Li, Guo-Wei Qin, Jian Fei, Li-He Gu. Inhibitive effects of Fructus Psoraleae extract on dopamine transporter and noradrenaline transporter. Journal of ethnopharmacology. vol 112. issue 3. 2007-12-12. PMID:17555897. |
a petroleum ether extract (fp) from fructus psoraleae, seeds of psoralea corylifolia l. (leguminosae), was found to strongly inhibit dopamine (da) uptake by dopamine transporter (dat) heterogeneously expressed cells (d8 cells) and noradrenaline (ne) uptake by noradrenaline transporter (net) heterogeneously expressed cells, which, however, had no effect on gamma-aminobutyric acid transporter heterogeneously expressed cells and serotonin transporter heterogeneously expressed cells at the concentration up to 100 microg/ml. |
2007-12-12 |
2023-08-12 |
mouse |
| Paulo H C Diniz, Janice H Silva, Marcus V Gomez, Cristina Guatimosim, Renato S Gome. Halothane increases non-vesicular [(3)H]dopamine release from brain cortical slices. Cellular and molecular neurobiology. vol 27. issue 6. 2007-12-07. PMID:17680357. |
these data suggest that [(3)h]da release induced by halothane is non-vesicular and would be mediated by the dopamine transporter (dat) and norepinephrine transporter (net). |
2007-12-07 |
2023-08-12 |
rat |
| Chin-Bin Yeh, Chung-Shian Lee, Kuo-Hsing Ma, Meei-Shyuan Lee, Chia-Jung Chang, Wen-Sheng Huan. Phasic dysfunction of dopamine transmission in Tourette's syndrome evaluated with 99mTc TRODAT-1 imaging. Psychiatry research. vol 156. issue 1. 2007-12-07. PMID:17716877. |
brain (99m)tc trodat-1 dopamine transporter (dat) single photon emission computed tomography (spect) was performed 5 days before, and 2 h after 10 mg of orally administered mph. |
2007-12-07 |
2023-08-12 |
Not clear |
| C H Kim, K A Cheon, M-S Koo, Y H Ryu, J D Lee, J W Chang, H S Le. Dopamine transporter density in the basal ganglia in obsessive-compulsive disorder, measured with [123I]IPT SPECT before and after treatment with serotonin reuptake inhibitors. Neuropsychobiology. vol 55. issue 3-4. 2007-12-03. PMID:17657168. |
using iodine-123-labeled n-(3-iodopropen-2-yl)-2 beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ([(123)i]ipt) single photon emission computed tomography (spect), we investigated the dopamine transporter (dat) density in the basal ganglia of patients with ocd. |
2007-12-03 |
2023-08-12 |
Not clear |
| Jay D Amsterdam, Andrew B Newber. A preliminary study of dopamine transporter binding in bipolar and unipolar depressed patients and healthy controls. Neuropsychobiology. vol 55. issue 3-4. 2007-12-03. PMID:17657170. |
we examined striatal dopamine transporter (dat) binding in bipolar and unipolar depressed patients and compared these values to those obtained from healthy control subjects using the selective dat radioligand [(99m)tc]trodat-1 and single photon emission computed tomography imaging. |
2007-12-03 |
2023-08-12 |
human |
| Lane J Wallac. A small dopamine permeability of storage vesicle membranes and end product inhibition of tyrosine hydroxylase are sufficient to explain changes occurring in dopamine synthesis and storage after inhibition of neuron firing. Synapse (New York, N.Y.). vol 61. issue 9. 2007-11-29. PMID:17559092. |
the vast majority of da in the cytosol arrives there via "recycling"--da that was released during an exocytotic event is moved into the cytosol via the dopamine transporter (dat). |
2007-11-29 |
2023-08-12 |
Not clear |