| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Roselli, Nicola M Pisciotta, Robert Perneczky, Michele Pennelli, Maria S Aniello, Maria F De Caro, Ermanno Ferrannini, Bruno Tartaglione, Giovanni Defazio, Giuseppe Rubini, Paolo Livre. Severity of neuropsychiatric symptoms and dopamine transporter levels in dementia with Lewy bodies: a 123I-FP-CIT SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 14. 2010-01-12. PMID:19705471. |
dopamine transporter (dat) imaging with (123)i-labeled ligand n-delta-(fluoropropyl)-2 beta-carbomethoxy-3beta-(4-iodophenyl)tropene ((123)i-fp-cit), which reliably measures midbrain dopaminergic dysfunction, has provided important evidence on the neurobiological substrate of some of these symptoms including apathy and depression. |
2010-01-12 |
2023-08-12 |
Not clear |
| E Escubedo, J Camarasa, C Chipana, S García-Ratés, D Pubil. Involvement of nicotinic receptors in methamphetamine- and MDMA-induced neurotoxicity: pharmacological implications. International review of neurobiology. vol 88. 2010-01-08. PMID:19897077. |
mem also prevents mdma effect on serotonin transporter functionality and meth effect on dopamine transporter (dat), suggesting that behavioral effects of these psychostimulants can also be modulated by mem. |
2010-01-08 |
2023-08-12 |
mouse |
| Masanori Ookubo, Hironori Yokoyama, Hiroyuki Kato, Tsutomu Arak. Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice. Molecular and cellular endocrinology. vol 311. issue 1-2. 2010-01-06. PMID:19631714. |
in the present study, we investigated the time-dependent alterations of dopamine and its metabolites, striatal tyrosine hydroxylase (th) protein, dopamine transporter (dat) protein, glial fibrillary acidic protein (gfap) protein and midbrain th protein and motor function in male and female mice 5h and 1, 3 and 7 days after four administrations of mptp (20mg/kg) at 2-h intervals. |
2010-01-06 |
2023-08-12 |
mouse |
| Hiroko Hagiwara, Masaomi Iyo, Kenji Hashimot. Mithramycin protects against dopaminergic neurotoxicity in the mouse brain after administration of methamphetamine. Brain research. vol 1301. 2010-01-05. PMID:19748494. |
moreover, the combination of pretreatment and subsequent administration of mithramycin (75, 150 or 300 microg/kg) significantly attenuated the reductions of dopamine (da), its major metabolite 3,4-dihydroxyphenylacetic acid (dopac) and da transporter (dat) in the striatum after repeated administration of meth (3 mg/kgx3, 3-h intervals), and these attenuations were dose dependent. |
2010-01-05 |
2023-08-12 |
mouse |
| G Kägi, K P Bhatia, E Tolos. The role of DAT-SPECT in movement disorders. Journal of neurology, neurosurgery, and psychiatry. vol 81. issue 1. 2010-01-05. PMID:20019219. |
dopamine transporter (dat) imaging is a sensitive method to detect presynaptic dopamine neuronal dysfunction, which is a hallmark of neurodegenerative parkinsonism. |
2010-01-05 |
2023-08-12 |
Not clear |
| Aina W Ravna, Ingebrigt Sylte, Svein G Dah. Structure and localisation of drug binding sites on neurotransmitter transporters. Journal of molecular modeling. vol 15. issue 10. 2009-12-31. PMID:19238460. |
the dopamine (dat), serotontin (sert) and noradrenalin (net) transporters are molecular targets for different classes of psychotropic drugs. |
2009-12-31 |
2023-08-12 |
Not clear |
| S Arpin, E Lagrue, S Bodard, S Chalon, P Castelna. Basal ganglia neuroprotection with anticonvulsants after energy stress: a comparative study. Metabolic brain disease. vol 24. issue 3. 2009-12-30. PMID:19789969. |
the membrane dopamine transporter (dat) density, which provides a reliable index of dopaminergic neurons survival in the basal ganglia, was assessed by semi-quantitative autoradiography of the striatum. |
2009-12-30 |
2023-08-12 |
mouse |
| Patrick J Riss, Fabian Debus, René Hummerich, Ulrich Schmidt, Patrick Schloss, Hartmut Lueddens, Frank Roesc. Ex vivo and in vivo evaluation of [18F]PR04.MZ in rodents: a selective dopamine transporter imaging agent. ChemMedChem. vol 4. issue 9. 2009-12-29. PMID:19588472. |
n-4-fluorobut-2-yn-1-yl-2beta-carbomethoxy-3beta-phenyltropane (pr04.mz) has been developed as dopamine transporter (dat) ligand for molecular imaging. |
2009-12-29 |
2023-08-12 |
human |
| Ryosuke Arakawa, Tetsuya Ichimiya, Hiroshi Ito, Akihiro Takano, Masaki Okumura, Hidehiko Takahashi, Harumasa Takano, Fumihiko Yasuno, Motoichiro Kato, Yoshiro Okubo, Tetsuya Suhar. Increase in thalamic binding of [(11)C]PE2I in patients with schizophrenia: a positron emission tomography study of dopamine transporter. Journal of psychiatric research. vol 43. issue 15. 2009-12-24. PMID:19457493. |
previous in vivo imaging studies reported no difference in dopamine transporter (dat) bindings in the striatum between control subjects and patients with schizophrenia. |
2009-12-24 |
2023-08-12 |
human |
| Simone Macrì, Oleg Granstrem, Maria Shumilina, Fernando João Antunes Gomes dos Santos, Alessandra Berry, Luciano Saso, Giovanni Laviol. Resilience and vulnerability are dose-dependently related to neonatal stressors in mice. Hormones and behavior. vol 56. issue 4. 2009-12-22. PMID:19632235. |
offspring attentional set-shifting abilities, central neurotrophic regulation and levels of natural auto-antibodies (na-abs) directed to serotonin (sert) and dopamine (dat) transporters were assessed in adulthood. |
2009-12-22 |
2023-08-12 |
mouse |
| S Padmanabhan, B M Prasa. Sustained depolarization decreases calcium/calmodulin-dependent protein kinase II activity and gene expression in dopamine neurons. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19555740. |
decreased camkii activity was accompanied by a selective decrease in dopamine transporter (dat) mrna, while tyrosine hydroxylase and actin mrna abundance was unaltered. |
2009-12-15 |
2023-08-12 |
rat |
| Jie Lan, Manshu Song, Chunhui Pan, Guoqing Zhuang, Youxin Wang, Wenzhan Ma, Qiaoyun Chu, Qingxuan Lai, Feng Xu, Yanli Li, Lixin Liu, Wei Wan. Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese. Journal of human genetics. vol 54. issue 8. 2009-12-15. PMID:19590515. |
there was evidence that the activities of dopamine transporter (dat) and dopamine d2 receptor (drd2) could be altered in people with speech disfluency. |
2009-12-15 |
2023-08-12 |
Not clear |
| Anna Grzywacz, Jerzy Samochowie. [Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence]. Psychiatria polska. vol 42. issue 3. 2009-12-04. PMID:19899571. |
[case-control, family based and screening for dna sequence variation in the dopamine transporter gene polymorphism dat 1 in alcohol dependence]. |
2009-12-04 |
2023-08-12 |
human |
| Anna Grzywacz, Jerzy Samochowie. [Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence]. Psychiatria polska. vol 42. issue 3. 2009-12-04. PMID:19899571. |
the paper focuses on candidate gene polymorphism and on the role of dopamine transporter gene polymorphism dat 1 in the pathogenesis of alcoholism. |
2009-12-04 |
2023-08-12 |
human |
| Anna Grzywacz, Jerzy Samochowie. [Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence]. Psychiatria polska. vol 42. issue 3. 2009-12-04. PMID:19899571. |
screening for dna sequence variation in the dopamine transporter gene polymorphism dat 1 was determined using abi 310. |
2009-12-04 |
2023-08-12 |
human |
| Anne Dreiem, Mangting Shan, Richard J Okoniewski, Susana Sanchez-Morrissey, Richard F Seega. Methylmercury inhibits dopaminergic function in rat pup synaptosomes in an age-dependent manner. Neurotoxicology and teratology. vol 31. issue 5. 2009-12-03. PMID:19464365. |
here, we determine whether mehg exposure also leads to greater changes in dopamine (da) levels and dopamine transporter (dat) function in synaptosomes from early postnatal rats. |
2009-12-03 |
2023-08-12 |
rat |
| Amy M Knab, Robert S Bowen, Alicia T Hamilton, Alyssa A Gulledge, J Timothy Lightfoo. Altered dopaminergic profiles: implications for the regulation of voluntary physical activity. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19520120. |
this study investigated differences in the central mrna expression of seven dopamine genes (drd1, drd2, drd3, drd4, drd5, th, and dat) between high active c57/lj (n=17) male mice and low active c3h/hej (n=20) male mice, and between mice with access to a running wheel and without running wheel access within strain. |
2009-12-01 |
2023-08-12 |
mouse |
| Susanne Nikolaus, Christina Antke, Hans-Wilhelm Mülle. In vivo imaging of synaptic function in the central nervous system: II. Mental and affective disorders. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19523495. |
patients with tourette syndrome exhibited increases of dat binding in the neostriatum (5 out of 10 reports) increases of dopamine storage and dopamine release in the ventral striatum (1 report, each). |
2009-12-01 |
2023-08-12 |
human |
| Marek Schwendt, Angelica Rocha, Ronald E See, Alejandra M Pacchioni, Jacqueline F McGinty, Peter W Kaliva. Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion. The Journal of pharmacology and experimental therapeutics. vol 331. issue 2. 2009-11-30. PMID:19648469. |
furthermore, long-, but not short-access to self-administered methamphetamine resulted in persistent decreases in dopamine transporter (dat) protein levels in the prefrontal cortex and dorsal striatum. |
2009-11-30 |
2023-08-12 |
rat |
| C Pellicano, F R Buttarelli, A Circella, D Tiple, M Giovannelli, D Benincasa, C Colosimo, F E Pontier. Dopamine transporter immunoreactivity in peripheral blood lymphocytes discriminates Parkinson's disease from essential tremor. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 7. 2009-11-23. PMID:17260170. |
in this study, densitometric analysis was applied to measure dopamine transporter (dat) immunoreactivity in pbl from dopaminergic drug-free patients suffering pd or essential tremor (et) with respect to healthy subjects. |
2009-11-23 |
2023-08-12 |
human |