| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nikhil Reddy, Fadi S Odish, Sangeeta Agrawa. Macro-Aspartate Aminotransferase: A Benign Cause of Abnormal Laboratory Findings. Cureus. vol 14. issue 4. 2022-05-09. PMID:35530879. |
macro-enzyme aspartate aminotransferase (macro-ast) is an uncommon and benign cause of persistently elevated ast levels in the absence of other diseases. we present a case of macro-ast in an otherwise healthy adult male which was confirmed by polyethylene glycol (peg) precipitation. |
2022-05-09 |
2023-08-13 |
Not clear |
| Mohammad Alam Miah, Mainul Hassan Himel, Khaled Mahmud Sujan, Afrina Mustari, Md Iqramul Haqu. Protective effects of cinnamon powder against hyperlipidemia and hepatotoxicity in butter fed female albino mice. Saudi journal of biological sciences. vol 29. issue 4. 2022-05-09. PMID:35531151. |
in butter-fed mice, a significant increase was observed in the liver enzymes, alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels with subsequent fat deposition in the liver. |
2022-05-09 |
2023-08-13 |
mouse |
| Guo-Ying Li, Wen-Jing Chen, Bu-Yun Jia, Xiang He, Dan-Dan Wang, Guang-Liang Che. [Di'ao Xinxuekang alleviates non-alcoholic steatohepatitis in mice by up-regulating Nrf2/HO-1 signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 9. 2022-05-09. PMID:35531696. |
serum lipid, liver lipid, serum alanine aminotransferase(alt), aspartate aminotransferase(ast), malondialdehyde(mda), superoxide dismutase(sod), and glutathione reductase(gsh-px) were determined. |
2022-05-09 |
2023-08-13 |
mouse |
| Fang-Wei Zhong, Geng-Xi Li, Li Zen. [Gynostemma pentaphyllum saponins alleviate non-alcoholic fatty liver disease in rats by regulating intestinal flora and short-chain fatty acid metabolism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 9. 2022-05-09. PMID:35531697. |
after intragastric administration for 8 continuous weeks, we determined the body weight, liver weight, the levels of total cholesterol(tc), triglyceride(tg), low-density lipoprotein cholesterol(ldl-c), high-density lipoprotein cholesterol(hdl-c), alanine aminotransferase(alt), and aspartate aminotransferase(ast) in serum, and the levels of tc, tg, malondialdehyde(mda), superoxide dismutase(sod), catalase(cat), and interleukin 6(il-6) in the liver. |
2022-05-09 |
2023-08-13 |
rat |
| Cheng-Fang Jian, Bo-Yu Zhang, Cun-Ping Wang, Yu-Ru Sha, A-Rong Li, Pu-Yang Gong, Jian Gu, Rui Ta. [Mechanism of Tibetan medicine Ershiwuwei Songshi Pills in regulating intestinal flora and improving non-alcoholic steatohepatitis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 8. 2022-05-09. PMID:35531719. |
the levels of serum aspartate aminotransferase(ast) and alanine aminotransferase(alt) and triglyceride(tg) in liver tissue were measured. |
2022-05-09 |
2023-08-13 |
mouse |
| Yu-Ru Sha, Xiao-Min Luo, Yi Ding, Bin Yang, Cheng-Fang Jian, Pu-Yang Gong, Jian Gu, Rui Ta. [Mechanism of Tibetan medicine Ershiwuwei Songshi Pills against liver injury induced by acetaminophen in mice based on Keap1/Nrf2 and TLR4/NF-κB p65 signaling pathways]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 8. 2022-05-09. PMID:35531720. |
hematoxylin-eosin(he) staining was performed on pathological sections of the liver, and the levels of aspartate aminotransferase(ast) and alanine aminotransferase(alt) in the serum and the levels of glutathione(gsh), malondialdehyde(mda), superoxide dismutase(sod), catalase(cat), myeloperoxidase(mpo), and total antioxidant capacity(t-aoc) in liver tissue homogenate were detected to observe and analyze the protective effect of esp on apap-induced liver injury in mice. |
2022-05-09 |
2023-08-13 |
mouse |
| A-Rong Li, Cun-Ping Wang, Yi Ding, Cheng-Fang Jian, Le Zhang, Jian Gu, Rui Ta. [Serum metabolomics of Tibetan medicine Ershiwuwei Songshi Pills against chronic cholestasis in mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 8. 2022-05-09. PMID:35531721. |
the results showed that esp was effective in improving pathological injury and reducing serum levels of alanine aminotransferase(alt), aspartate aminotransferase(ast), alkaline phosphatase(alp), and total bile acid in the model mice. |
2022-05-09 |
2023-08-13 |
mouse |
| Hong-Shuang Liu, Ya-Lan Li, Jing-Wei Kong, Man-Yu Zhou, Rui-Juan Dong, Dong-Yu Ge, Jia-Jing Liu, Gui-Ying Peng, Yan Lia. [Sagittaria sagittifolia polysaccharides regulates Nrf2/HO-1 to relieve liver injury caused by multiple heavy metals in vivo and in vitro]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 7. 2022-05-09. PMID:35534262. |
the content of alanine transaminase(alt) and aspartate aminotransferase(ast) in the 48-h cell culture fluid was measured using micro-plate cultivation method, followed by the detection of the change in reactive oxygen species(ros) content by flow cytometry. |
2022-05-09 |
2023-08-13 |
mouse |
| Dan Li, Jiang Qian, Junfeng Li, Jia Wang, Wenhong Liu, Qinfei Li, Dan W. Dexmedetomidine attenuates acute stress-induced liver injury in rats by regulating the miR-34a-5p/ROS/JNK/p38 signaling pathway. The Journal of toxicological sciences. vol 47. issue 5. 2022-05-08. PMID:35527005. |
contents of norepinephrine (ne), alanine aminotransfease (alt) and aspartate aminotransferase (ast) in serum of rats were detected by enzyme-linked immunosorbent assay (elisa) and those of oxidative stress markers (reactive oxygen species (ros), malondialdehyde (mda), glutathione (gsh), superoxide dismutase (sod) and glutathione peroxidase (gpx)) were measured using commercial kits. |
2022-05-08 |
2023-08-13 |
rat |
| Zehra Öksüz, Enver Üçbilek, Mehmet Sami Serin, Serkan Yaraş, Gülhan Örekici Temel, Orhan Sezgi. hsa-miR-17-5p: A Possible Predictor of Ombitasvir/Paritaprevir/Ritonavir + Dasabuvir ± Ribavirin Therapy Efficacy in Hepatitis C Infection. Current microbiology. vol 79. issue 6. 2022-05-07. PMID:35524830. |
moreover, a significant difference was found between the mrna levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and hcv rna pre-and post-treatment (p < 0.05). |
2022-05-07 |
2023-08-13 |
Not clear |
| Hongtao Wang, Ying Feng, Meiyu Ming, Jingjing Song, Zhiheng Chen, Zhi Xia. Amelioration of Cd-induced bioaccumulation, hematological parameters, and heat shock protein-related genes by Vitamin C on common carp. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022-05-07. PMID:35525466. |
the results obtained indicate that vitamin c can provide a significant protective effect on the toxicity of cadmium by inhibiting alterations in the levels of bioaccumulation, hematological parameters (including calcium, magnesium, glucose, alkaline phosphatase (alp), glutamic-pyruvic transaminase (alt), aspartate transaminase (ast), total protein, lactate dehydrogenase (ldh), cholesterol and lysozyme (lzm)) and heat shock protein-related genes (hsp70, hsp90, hsp47 and hsp60). |
2022-05-07 |
2023-08-13 |
human |
| Julie Osborn, Sara Szabo, Anna L Peter. Pediatric Acute Liver Failure Due to Type 2 Autoimmune Hepatitis Associated With SARS-CoV-2 Infection: A Case Report. JPGN reports. vol 3. issue 2. 2022-05-04. PMID:35505826. |
treatment with high-dose methylprednisolone resulted in rapid normalization of alanine aminotransferase (alt), aspartate aminotransferase (ast), international normalized ratio (inr), and ammonia levels, and liver transplantation was avoided. |
2022-05-04 |
2023-08-13 |
Not clear |
| Concetta Saoca, Francesca Arfuso, Claudia Giannetto, Giuseppe Piccione, Francesco Fazi. Seasonal Biodistribution of Some Trace Elements (Cd, Pb, Cr, Hg) and "Blood Biomarkers" Response in Mugil cephalus (Linnaeus, 1758). Biological trace element research. 2022-05-04. PMID:35508888. |
the hematological (white blood cell, wbc; red blood cell, rbc; hemoglobin concentration, hb; hematocrit, hct; mean corpuscular volume, mcv; mean corpuscular hemoglobin, mch; mean corpuscular hemoglobin concentration, mchc; thrombocytes count, tc), biochemical parameters (aspartate aminotransferase, ast; alanine aminotransferase, alt; alkaline phosphatase, alp; lactate dehydrogenase, ldh), and the seasonal concentration of the trace elements in the different tissues of m. cephalus were assessed. |
2022-05-04 |
2023-08-13 |
Not clear |
| T Akbulut, V Cinar, K Ugur, M Yardim, Z K Karagoz, S Aydi. Effect of regular exercise on the levels of subfatin and asprosin: a trial with different types of exercise. European review for medical and pharmacological sciences. vol 26. issue 8. 2022-05-03. PMID:35503613. |
the present study aimed to investigate the effects of different types of regular exercises on levels of subfatin, asprosin, aspartate aminotransferase (ast), alanine aminotransferase (alt), uric acid, and glucose. |
2022-05-03 |
2023-08-13 |
Not clear |
| Mohsen Sedighi, Alireza Amanollahi, Omid Moradi Moghaddam, Hamed Basir Ghafouri, Seyede Elahe Hoseini, Nader Tavakol. Linear mixed model analysis to evaluate correlations between remdesivir adverse effects with age and gender of patients with mild Covid-19 pneumonia. Journal of medical virology. 2022-05-02. PMID:35491957. |
there were significant increases in mean levels of white blood cell (wbc) (p=0.005), alanine aminotransferase (alt) (p=0.001), aspartate aminotransferase (ast) (p=0.001), blood urea nitrogen (bun) (p=0.001), and creatinine (p=0.006) while mean levels of erythrocyte sedimentation rate (esr) (p=0.005), c-reactive protein (crp) (p=0.001), alkaline phosphatase (alp) (p=0.001), and potassium (p=0.003) decreased, significantly. |
2022-05-02 |
2023-08-13 |
Not clear |
| Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Jae Young Jang, Soo Young Park, Hyun Woong Lee, Chun Kyon Lee, Seung Up Ki. Comparison of FibroScan-Aspartate Aminotransferase (FAST) Score and Other Non-invasive Surrogates in Predicting High-Risk Non-alcoholic Steatohepatitis Criteria. Frontiers in medicine. vol 9. 2022-05-02. PMID:35492369. |
the fast score was calculated using transient elastography data and aspartate aminotransferase (ast) levels. |
2022-05-02 |
2023-08-13 |
Not clear |
| Jayanthi Yadav, Garima Goel, Shashank Purwar, Saurabh Saigal, Ashwani Tandon, Ankur Joshi, Brinda Patel, Sravan Js, Mahaluxmi S, Jitendra Singh, Prem Shankar, Arneet Arora, Sarman Sing. Clinical, Virological, and Pathological Profile of Patients Who Died of COVID-19: An Autopsy-Based Study From India. Cureus. vol 14. issue 3. 2022-05-02. PMID:35494966. |
an association was observed between antemortem biochemical parameters [aspartate aminotransferase (ast), alanine aminotransferase (alt)] and the histopathological features in the liver. |
2022-05-02 |
2023-08-13 |
Not clear |
| Xiuhong Lyu, John Miskovsk. Detecting Concealing Heart Failure in a Young Alcohol-Related Liver Failure Patient Using the Most Basic Pathophysiological Principle. Cureus. vol 14. issue 3. 2022-05-02. PMID:35495021. |
labs showed elevated total bilirubin, aspartate aminotransferase (ast), alanine aminotransferase (alt), ammonia, and lactate levels. |
2022-05-02 |
2023-08-13 |
Not clear |
| Oluwatosin A Arojojoye, Olajumoke O Nwaechefu, Samuel C Nkwadinamo. Evaluation of genotoxic and oxidative stress potential of Ajakanga Landfill Leachate in rats. Environmental analysis, health and toxicology. vol 37. issue 1. 2022-05-02. PMID:35500887. |
the effect of the leachate was assessed on markers of oxidative stress in the liver, kidney and testes of rats; markers of liver function (alanine aminotransferase (alt) and aspartate aminotransferase (ast) were determined in the serum and the genotoxic effect of the leachate was investigated using micronucleus assay. |
2022-05-02 |
2023-08-13 |
rat |
| Akiko Eguchi, Motoh Iwasa, Minori Yamada, Yasuyuki Tamai, Ryuta Shigefuku, Hiroshi Hasegawa, Yoshifumi Hirokawa, Akinobu Hayashi, Koji Okuno, Yuki Matsushita, Takuma Nakatsuka, Kenichiro Enooku, Koji Sakaguchi, Yoshinao Kobayashi, Tetsuji Yamaguchi, Masatoshi Watanabe, Yoshiyuki Takei, Hayato Nakagaw. A new detection system for serum fragmented cytokeratin 18 as a biomarker reflecting histologic activities of human nonalcoholic steatohepatitis. Hepatology communications. 2022-04-29. PMID:35485207. |
serum fck18 levels were significantly correlated with alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transpeptidase. |
2022-04-29 |
2023-08-13 |
human |