| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maryam Farazandeh, Maryam Mahmoudabady, Ali Akbar Asghari, Saeed Niazman. Diabetic cardiomyopathy was attenuated by cinnamon treatment through the inhibition of fibro-inflammatory response and ventricular hypertrophy in diabetic rats. Journal of food biochemistry. 2022-04-27. PMID:35474577. |
fasting blood sugar (fbs) and markers of cardiac injury including creatine kinase-muscle/brain (ck-mb), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh) were evaluated in blood samples. |
2022-04-27 |
2023-08-13 |
human |
| Yu Fujiwara, Nobuyuki Horita, Matthew Harrington, Ho Namkoong, Hirotaka Miyashita, Matthew D Galsk. Incidence of hepatotoxicity associated with addition of immune checkpoint blockade to systemic solid tumor therapy: a meta-analysis of phase 3 randomized controlled trials. Cancer immunology, immunotherapy : CII. 2022-04-26. PMID:35471602. |
the odds ratio (or) of any grade and grade 3-5 hepatitis, elevations in aspartate aminotransferase (ast), and alanine aminotransferase (alt) was pooled for meta-analysis. |
2022-04-26 |
2023-08-13 |
human |
| Xuehong Yin, Ran Xue, Jing Wu, Muchen Wu, Bangxiang Xie, Qinghua Men. PINK1 ameliorates acute-on-chronic liver failure by inhibiting apoptosis through mTORC2/AKT signaling. Cell death discovery. vol 8. issue 1. 2022-04-24. PMID:35461334. |
herein, our team discovered that pink1 remarkably improved aclf, featured by a reduction in aspartate aminotransferase (ast) and alanine aminotransferase (alt) and an amelioration in the gross and microscopy histopathology appearance of hepatic tissues. |
2022-04-24 |
2023-08-13 |
Not clear |
| Kei Nakajima, Mariko Yuno, Kazumi Tanaka, Teiji Nakamur. High Aspartate Aminotransferase/Alanine Aminotransferase Ratio May Be Associated with All-Cause Mortality in the Elderly: A Retrospective Cohort Study Using Artificial Intelligence and Conventional Analysis. Healthcare (Basel, Switzerland). vol 10. issue 4. 2022-04-23. PMID:35455851. |
low serum alanine aminotransferase (alt) activity and high aspartate aminotransferase (ast)/alt ratio may be associated with high mortality in the elderly. |
2022-04-23 |
2023-08-13 |
human |
| Shanshan Su, Qingqing Wang, Fang Wei, Guoqi Zhen. Effect of Modified Xianglian Pingwei Powder plus Glutathione and Levofloxacin Hydrochloride on Patients with Liver Cirrhosis and Positive Small Intestinal Bacterial Overgrowth. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-04-22. PMID:35449813. |
the traditional chinese medicine (tcm) syndrome scores, serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and total bilirubin (tbil) levels of the two groups were decreased after treatment with lower results in the study group. |
2022-04-22 |
2023-08-13 |
Not clear |
| Shang-Lin Li, Zhi-Min Wang, Cong Xu, Fu-Heng Che, Xiao-Fan Hu, Rui Cao, Ya-Nan Xie, Yang Qiu, Hui-Bo Shi, Bin Liu, Chen Dai, Jun Yan. Liraglutide Attenuates Hepatic Ischemia-Reperfusion Injury by Modulating Macrophage Polarization. Frontiers in immunology. vol 13. 2022-04-22. PMID:35450076. |
our results showed that liraglutide pretreatment significantly alleviated the liver damage caused by ischemia-reperfusion (i/r), as evidenced by h&e staining, serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels, and tunel staining. |
2022-04-22 |
2023-08-13 |
Not clear |
| Kaustubh Singh, Vivek Kumar, K K Gupta, Ajay Kumar Patwa, Sudhir Kumar Verm. A comparative study of novel fibrosis index and transient elastography for predicting fibrosis in patients of chronic liver disease. The Journal of the Association of Physicians of India. vol 70. issue 4. 2022-04-21. PMID:35443492. |
these are biomarkers (aspartate transaminase (ast) to alanine transaminase (alt) ratio (aar), ast to platelet ratio index (apri), fibrosis index (fi), fibrosis-4 (fib-4), age platelet index (api), pohl score, fibrosis cirrhosis index (fci)) and transient elastography. |
2022-04-21 |
2023-08-13 |
Not clear |
| Lvfeng Yao, Jianzhong Zhang, Jie Jin, Hongbin Li, Lei Li, Xian Han, Hafiz Khuram Raza, Xiaoyun Li, Yimin Ma. An analysis of the efficacy and safety of compound glycyrrhizin injections in the treatment of drug-induced liver injury using a nationwide database. International journal of clinical pharmacy. 2022-04-19. PMID:35438473. |
the efficacy of the cg injections was assessed by the analysis of alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels between the two groups. |
2022-04-19 |
2023-08-13 |
Not clear |
| Bingtian Dong, Yuping Chen, Guorong Lyu, Yongjian Chen, Ran Qi. Quantitative Assessment of Portal Hypertension by Two-Dimensional Shear Wave Elastography in Rat Models of Nonalcoholic Fatty Liver Disease: Comparison With Four Composite Scores. Frontiers in medicine. vol 9. 2022-04-18. PMID:35433761. |
we aimed to assess the performance in liver and spleen stiffness measurement (lsm and ssm, respectively) by two-dimensional shear wave elastography (2d-swe) and composite scores including liver stiffness-spleen diameter to platelet ratio score (lsps), platelet (plt) count/spleen diameter ratio (psr), aspartate aminotransferase (ast)/alanine aminotransferase ratio (aar), and ast-to-plt ratio index (apri) for diagnosing ph in nonalcoholic fatty liver disease (nafld) rat models. |
2022-04-18 |
2023-08-13 |
rat |
| Pan Li, Yuwei Chen, Xiumei Ke, Ruoyu Zhang, Ling Zuo, Meng Wang, Zhiwei Chen, Xianqin Luo, Jianwei Wan. Baicalin ameliorates alcohol-induced hepatic steatosis by suppressing SREBP1c elicited PNPLA3 competitive binding to ATGL. Archives of biochemistry and biophysics. 2022-04-16. PMID:35429444. |
it was evident that baicalin treatment significantly normalized the serous contents of hepatic triglyceride (tg), alanine aminotransferase (alt), and aspartate aminotransferase (ast), and attenuated the increase of hepatic vacuolization and oil red o staining area caused by alcohol. |
2022-04-16 |
2023-08-13 |
rat |
| Tinsay A Woreta, Mark L Van Natta, Mariana Lazo, Arunkumar Krishnan, Brent A Neuschwander-Tetri, Rohit Loomba, Anna Mae Diehl, Manal F Abdelmalek, Naga Chalasani, Samer Gawrieh, Srinivasan Dasarathy, Raj Vuppalanchi, Mohammad S Siddiqui, Kris V Kowdley, Arthur McCullough, Norah A Terrault, Cynthia Behling, David E Kleiner, Mark Fishbein, Paula Hertel, Laura A Wilson, Emily P Mitchell, Laura A Miriel, Jeanne M Clark, James Tonascia, Arun J Sanya. Validation of the accuracy of the FAST™ score for detecting patients with at-risk nonalcoholic steatohepatitis (NASH) in a North American cohort and comparison to other non-invasive algorithms. PloS one. vol 17. issue 4. 2022-04-15. PMID:35427375. |
the new fast™ score, a combination of fibroscan® parameters liver stiffness measurement (lsm) and controlled attenuation parameter (cap) and aspartate aminotransferase (ast), has shown good diagnostic accuracy for at-risk nash (area-under-the-receiver-operating-characteristic [auroc] = 0.80) in european cohorts. |
2022-04-15 |
2023-08-13 |
Not clear |
| Huiru Xu, Huijing Feng, Weihong Zhang, Feng Wei, Li Zhou, Liang Liu, Yu Zhao, Yingge Lv, Xiuhuan Shi, Junping Zhang, Xiubao Re. Prediction of immune-related adverse events in non-small cell lung cancer patients treated with immune checkpoint inhibitors based on clinical and hematological markers: Real-world evidence. Experimental cell research. 2022-04-15. PMID:35427598. |
a prediction model based on treatment lines, aspartate aminotransferase (ast), lactate dehydrogenase (ldh), absolute lymphocyte count (alc), and systemic immune inflammation index was established. |
2022-04-15 |
2023-08-13 |
Not clear |
| Fabiano Moraes Miguel, Jaqueline Nascimento Picada, Juliana Bondan da Silva, Elizângela Gonçalves Schemitt, Josieli Raskopf Colares, Renata Minuzzo Hartmann, Cláudio Augusto Marroni, Norma Possa Marron. Melatonin Attenuates Inflammation, Oxidative Stress, and DNA Damage in Mice with Nonalcoholic Steatohepatitis Induced by a Methionine- and Choline-Deficient Diet. Inflammation. 2022-04-14. PMID:35419738. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were measured, and hepatic tissue was dissected for histological analysis, evaluation of lipoperoxidation, superoxide dismutase (sod), catalase (cat), and glutathione peroxidase (gpx), as well as nuclear factor-erythroid 2 (nrf2), tumor necrosis factor alpha (tnf-α), inducible nitric oxide synthase (inos), and transforming growth factor beta (tgf-β) expression by immunohistochemistry. |
2022-04-14 |
2023-08-13 |
mouse |
| Naghmeh Saadati-Eskandari, Latifeh Navidpour, Parichehreh Yaghmaei, Azadeh Ebrahim-Habib. Phenylalanine and indole effects on the pathogenicity of human lysozyme amorphous aggregates. Enzyme and microbial technology. vol 158. 2022-04-14. PMID:35421678. |
serum levels of liver enzymes (alanine aminotransferase (alt) and aspartate aminotransferase (ast)), specific inflammatory cytokines (tumor necrosis factor alpha (tnf-α) and interleukin 6 (il-6)) as well as glucose, cholesterol, and triglyceride levels were measured. |
2022-04-14 |
2023-08-13 |
human |
| Kiran Kousar Noor, Muhammad Umar Ijaz, Nazia Ehsan, Arfa Tahir, Derya Kertas Yeni, S M Neamul Kabir Zihad, Shaikh Jamal Uddin, Asma Ashraf, Jesus Simal-Gandar. Hepatoprotective role of vitexin against cadmium-induced liver damage in male rats: A biochemical, inflammatory, apoptotic and histopathological investigation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 150. 2022-04-14. PMID:35421786. |
after 30 days of treatment, it was indicated that cd escalated the level of liver function enzymes namely alanine transaminase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) as well as total bilirubin. |
2022-04-14 |
2023-08-13 |
rat |
| Shira Zelber-Sagi, Vikas N O'Reilly-Shah, Christine Fong, Dana Ivancovsky-Wajcman, May J Reed, Itay Bento. Liver Fibrosis Marker and Postoperative Mortality in Patients Without Overt Liver Disease. Anesthesia and analgesia. 2022-04-13. PMID:35417420. |
the aim of this study was to assess whether fibrosis-4 (fib-4), which consists of age, aspartate aminotransferase (ast), alanine aminotransferase (alt), and platelets, a validated marker of liver fibrosis, is associated with postoperative mortality in the general surgical population. |
2022-04-13 |
2023-08-13 |
Not clear |
| Katy Satué, Laura Miguel-Pastor, Deborah Chicharro, Juan Carlos Gardó. Hepatic Enzyme Profile in Horses. Animals : an open access journal from MDPI. vol 12. issue 7. 2022-04-12. PMID:35405850. |
these two groups of equine liver-specific enzymes include sorbitol dehydrogenase (sdh), glutamate dehydrogenase (gldh), γ-glutamyl transferase (ggt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), and alkaline phosphatase (alp). |
2022-04-12 |
2023-08-13 |
Not clear |
| Markus Galler, Julian M M Rogasch, Kai Huang, Henning Jann, Kristina Plehm, Christoph Wetz, Holger Amthaue. Prognostic Value of the Largest Lesion Size for Progression-Free Survival in Patients with NET Undergoing Salvage PRRT with [ Cancers. vol 14. issue 7. 2022-04-12. PMID:35406540. |
the purpose of this study was to evaluate two parameters that have shown prognostic significance in progression-free survival (pfs) in initial prrt treatment, namely the size of the largest lesion (lls) and the de ritis ratio (aspartate aminotransferase (ast)/alanine aminotransferase (alt)), as prognostic factors in the context of salvage prrt. |
2022-04-12 |
2023-08-13 |
Not clear |
| Jingyue Zhang, Shiheng Zhang, Yueming Yang, Ling Li. Transplantation of umbilical cord blood-derived mesenchymal stem cells as therapy for adriamycin induced-cardiomyopathy. Bioengineered. vol 13. issue 4. 2022-04-07. PMID:35387551. |
the serum levels of collagen-i (col-i), brain natriuretic peptide (bnp), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), creatine kinase (ck), ck-mb, interleukin (il)-6, il-10, and tumor necrosis factor alpha (tnf-α) were measured by corresponding kits. |
2022-04-07 |
2023-08-13 |
human |
| Qingfei Xiao, Ying Zhao, Lei Ma, Rongli Pia. Orientin reverses acetaminophen-induced acute liver failure by inhibiting oxidative stress and mitochondrial dysfunction. Journal of pharmacological sciences. vol 149. issue 1. 2022-04-04. PMID:35369900. |
our results indicated that ori alleviated apap-induced hepatic pathological changes by reducing mouse mortality, inhibiting the expression of cytochrome p450 2e1 (cyp2e1), maintaining a normal liver structure, and reducing the levels of serum alanine transaminase (alt) and serum aspartate aminotransferase (ast). |
2022-04-04 |
2023-08-13 |
mouse |