| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nalan Kaya Tektemur, Elif Erdem Güzel, Mehmet Gül, Ahmet Tektemur, Sena Özcan Yıldırım, Merve Kavak Balgetir, Gonca Ozan Kocamüftüoğlu, Tuba Yalçın, İbrahim Enver Oza. The combination of N-acetylcysteine and cyclosporin A reduces acetaminophen-induced hepatotoxicity in mice. Ultrastructural pathology. vol 45. issue 1. 2021-10-28. PMID:33530839. |
levels of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) and liver glutathione (gsh) were analyzed. |
2021-10-28 |
2023-08-13 |
mouse |
| Jun Komukai, Kenji Matsumoto, Shinzoh Kudoh, Akihiro Okado, Takashi Yoshiyama, Hideki Yoshida, Akira Shimouch. [Treatment outcome of latent tuberculosis infection in persons with fibrotic pulmonary lesions]. [Nihon koshu eisei zasshi] Japanese journal of public health. vol 68. issue 6. 2021-10-28. PMID:33790095. |
②cxr shows fibrotic pulmonary lesions.③fibrotic pulmonary lesions with cxr have not changed for more than one year.④quantiferon tb gold-in-tube (qft) shows positive values (≥0.35 iu/ml). before treatment, the blood samples were within the standard values for aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin, and serum creatinine. |
2021-10-28 |
2023-08-13 |
human |
| Lanman Xu, Xiaofang Wang, Yan Chen, Lynn Soong, Yongping Chen, Jiyang Cai, Yuejin Liang, Jiaren Su. Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis. Frontiers in immunology. vol 12. 2021-10-28. PMID:33968030. |
using an adenovirus (ad)-induced viral hepatitis mouse model, we found that metformin treatment significantly attenuated liver injury, with reduced serum aspartate transaminase (ast) and alanine transaminase (alt) levels and liver histological changes, presumably |
2021-10-28 |
2023-08-13 |
mouse |
| Ayodeji Adegoke, Michael A Gbadegesin, Oyeronke A Odunol. Hepato-Genoprotective Activities of Methanol Extract of The Stem Bark of Adansonia Digitata LINN. In Wistar Rats Challenged with Sodium Arsenite. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 35. issue 2. 2021-10-28. PMID:34009194. |
the sa significantly (p<0.05) increased the activities of aspartate aminotransferace (ast) and the number of micronucleated polychromatic erythrocytes (nmpces) induced in the bone marrow as compared with the negative control. |
2021-10-28 |
2023-08-13 |
rat |
| Ann-Yae Na, Jung Jae Jo, Oh Kwang Kwon, Piljoung Cho, Yan Gao, Ju-Hyun Kim, Kyu Min Kim, Sung Hwan Ki, Sangkyu Le. Characterization of hyperglycemia due to sub-chronic administration of red ginseng extract via comparative global proteomic analysis. Scientific reports. vol 11. issue 1. 2021-10-28. PMID:34117292. |
the 1.0 and 2.0 g/kg krg groups exhibited signs of liver injury, including increased levels of aspartate transaminase (ast) and alanine aminotransferase (alt) in the serum. |
2021-10-28 |
2023-08-13 |
mouse |
| b' Alice Elena Ghenea, Anca Marilena Ungureanu, Adriana Turculeanu, Mihaela Popescu, Mara Carsote, Maria Loredana \\xc5\\xa2ieranu, Eugen Nicolae \\xc5\\xa2ieranu, Corina Maria Vasile, Ramona Cioboat\\xc4\\x83, Anca Loredana Udri\\xc5\\x9ftoiu, Drago\\xc5\\x9f Ovidiu Alexandru, Alex Ioan S\\xc4\\x83lan, Andrei Ioan Droca\\xc5\\x9. Predictors of early and sustained virological response of viral hepatitis C. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 61. issue 4. 2021-10-28. PMID:34171067.' |
patients' recovery progress has been evaluated by determining: age, gender; biochemical tests: alanine aminotransferase (alt), aspartate aminotransferase (ast); serological assays - detect anti-hcv antibody and molecular assays - detect, quantify and/or characterize hepatitis c viral load (ribonucleic acid) (hcv-rna); liver histopathological (hp) examination. |
2021-10-28 |
2023-08-13 |
Not clear |
| Sohini Das, Sowmya Sathyendra, Julie Hephzibah, Reka Karuppusami, Karthik Gunasekaran, Nylla Shanthly, Angel Miraclin, Ramya Iyadura. Utility of positron emission tomography-computed tomography in the evaluation of fever of unknown origin in a resource-limited tropical nation. World journal of nuclear medicine. vol 20. issue 3. 2021-10-28. PMID:34703391. |
high c-reactive protein (crp) and aspartate aminotransferase (ast) levels were associated with contributory pet-ct scans ( |
2021-10-28 |
2023-08-13 |
Not clear |
| Jingnan Xu, Shurou Li, Liqiang Jiang, Xinxin Gao, Wei Liu, Xingyi Zhu, Wenlong Huang, Haiguang Zhao, Zhengkai Wei, Kai Wang, Zhengtao Yan. Baicalin protects against zearalenone-induced chicks liver and kidney injury by inhibiting expression of oxidative stress, inflammatory cytokines and caspase signaling pathway. International immunopharmacology. vol 100. 2021-10-27. PMID:34521024. |
the results exhibit that baicalin could not only significantly decrease aspartate aminotransferase (ast) , alanine aminotransferase (alt) and creatinine (cre) levels in serum, but also ameliorate zea-induced pathologic changes of liver and kidney. |
2021-10-27 |
2023-08-13 |
human |
| Jeong Namkung, Jung Hyun Park, Ji Hae Byun, Mee-Ran Ki. Elevated aspartate aminotransferase and alanine aminotransferase in the torsion of ovarian mature cystic teratoma: normalised after operation for torsion. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. vol 41. issue 4. 2021-10-26. PMID:32811218. |
of the 11 torsion of mct cases, 6 of those showed abnormal elevated levels of aspartate transaminase (ast)/alanine aminotransferase (alt). |
2021-10-26 |
2023-08-13 |
Not clear |
| Zhaofang Chen, Kexin Shi, Wenjie Kuang, Lei Huan. Exploration of the optimal strategy for dietary calcium intervention against the toxicity of liver and kidney induced by cadmium in mice: An in vivo diet intervention study. PloS one. vol 16. issue 5. 2021-10-26. PMID:33974642. |
results showed that serum aspartate aminotransferase (ast) level in cah+cd-group was significantly lower than that in cd-group, while close to that in control-group. |
2021-10-26 |
2023-08-13 |
mouse |
| Seyed Mohammad Mousavi, Ahmad Jayedi, Amir Bagheri, Nikan Zargarzadeh, Alexei Wong, Emma Persad, Camellia Akhgarjand, Fariba Koohdan. What is the influence of cinnamon supplementation on liver enzymes? A systematic review and meta-analysis of randomized controlled trials. Phytotherapy research : PTR. vol 35. issue 10. 2021-10-26. PMID:34212447. |
all trials assessing the effect of oral cinnamon supplementation on serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) in adults were included. |
2021-10-26 |
2023-08-13 |
human |
| Pascal Kintz, Laurie Gheddar, Camille Paradis, Mickael Chinellato, Alice Ameline, Jean-Sébastien Raul, Magali Oliva-Labadi. Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- δ) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine). Toxics. vol 9. issue 10. 2021-10-26. PMID:34678947. |
cytolysis with marked increase of alanine aminotransferase or alt (up to 922 ui/l) and aspartate aminotransferase or ast (up to 2558 ui/l) and massive rhabdomyolysis with elevated creatine phosphokinase or cpk (up to 86435 ui/l) were the main unusual biochemistry parameters. |
2021-10-26 |
2023-08-13 |
human |
| Huan Huang, Jianrong Zhang, Fuxing Gui, Sheng Liu, Chonghua Zhong, Tingting Wang, Hongxu Du, Xianlin He, Liting Ca. Development of a Simple Single-Acupoint Electroacupuncture Frame and Evaluation of the Acupuncture Effect in Rabbits. Veterinary sciences. vol 8. issue 10. 2021-10-26. PMID:34679047. |
blood samples aseptically collected from the ear vein 3 h before acupuncture and 0, 3, 6, 9, 12 and 24 h after acupuncture were used for the detection of aspartate aminotransferase (ast), alanine aminotransferase (alt), creatine kinase mb (ck-mb) and motilin (mtl) in serum. |
2021-10-26 |
2023-08-13 |
Not clear |
| James H Lewis, Michel Jadoul, Geoffrey A Block, Melanie P Chin, Deborah A Ferguson, Angie Goldsberry, Colin J Meyer, Megan O'Grady, Pablo E Pergola, Scott A Reisman, W Christian Wigley, Glenn M Cherto. Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD. Clinical and translational science. vol 14. issue 1. 2021-10-25. PMID:32860734. |
in a multinational placebo-controlled phase iii clinical trial in 2,185 patients with type 2 diabetes mellitus and stage 4 chronic kidney disease, treatment with the nrf2 activator bardoxolone methyl increased estimated glomerular filtration rate, a measure of kidney function, but also resulted in increases in serum alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma glutamyl transferase. |
2021-10-25 |
2023-08-13 |
mouse |
| Mehdi Goudarzi, Mojtaba Kalantar, Elahe Sadeghi, Mojtaba Haghi Karamallah, Hadi Kalanta. Protective effects of apigenin on altered lipid peroxidation, inflammation, and antioxidant factors in methotrexate-induced hepatotoxicity. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 3. 2021-10-25. PMID:33057777. |
alanine aminotransferase (alt), alkaline phosphatase (alp), and aspartate aminotransferase (ast) were used as biochemical factors of mtx-induced hepatic injury. |
2021-10-25 |
2023-08-13 |
rat |
| Mary Zosangzuali, Marina Lalremruati, C Lalmuansangi, F Nghakliana, Lalrinthara Pachuau, Priyanka Bandara, Zothan Siam. Effects of radiofrequency electromagnetic radiation emitted from a mobile phone base station on the redox homeostasis in different organs of Swiss albino mice. Electromagnetic biology and medicine. vol 40. issue 3. 2021-10-25. PMID:33687298. |
our findings showed no significant variations in the activities of aspartate amino-transferase (ast), alanine amino-transferase (alt), and on the level of creatinine (cre) in the exposed mice. |
2021-10-25 |
2023-08-13 |
mouse |
| E A Ahmed, A M Abd-Eldayem, E Ahme. Can granulocyte colony stimulating factor (G-CSF) ameliorate acetaminophen-induced hepatotoxicity? Human & experimental toxicology. vol 40. issue 10. 2021-10-25. PMID:33882750. |
elevated levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp) and lactate dehydrogenase (ldh) were evaluated for liver toxicity. |
2021-10-25 |
2023-08-13 |
rat |
| Chuan Gao, Anthony Marcketta, Joshua D Backman, Colm O'Dushlaine, Jeffrey Staples, Manuel Allen Revez Ferreira, Luca A Lotta, John D Overton, Jeffrey G Reid, Tooraj Mirshahi, Regeneron Genetics Center, Geisinger Regeneron Discovehr Collaboration, Aris Baras, Gonçalo Abecasis, Alan R Shuldiner, Cristopher V Van Hout, Shane McCarth. Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals. Genetic epidemiology. vol 45. issue 6. 2021-10-25. PMID:34184762. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) are biomarkers for liver health. |
2021-10-25 |
2023-08-13 |
Not clear |
| Taklo Simeneh Yazi. Derangement of Liver Enzymes, Hyperglycemia, Anemia, and Associated Factors among HIV-Infected Patients Treated with Tenofovir Disoproxil Fumarate-Based Regimen in Ethiopia: A Prospective Cohort Study. BioMed research international. vol 2021. 2021-10-25. PMID:34222476. |
from this, elevated alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) comprise 3 (4.8%), 3 (4.8%), and 20 (31.8%), respectively. |
2021-10-25 |
2023-08-13 |
human |
| Sakir Pekgöz, Halil Asci, Yalcin Erzurumlu, Mehtap Savran, Ilter Ilhan, Nursel Hasseyid, Metin Ciri. Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling. Drug and chemical toxicology. 2021-10-25. PMID:34693844. |
at the end of the experiment, bloods were taken for aspartate transaminase (ast), alanine aminotransferase (alt), and total bilirubin (t-bil) analyses. |
2021-10-25 |
2023-08-13 |
rat |