| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Catalina M Mascaró, Cristina Bouzas, Sofia Montemayor, Miguel Casares, Cristina Gómez, Lucía Ugarriza, Pere-Antoni Borràs, José Alfredo Martínez, Josep A Tu. Association between Physical Activity and Non-Alcoholic Fatty Liver Disease in Adults with Metabolic Syndrome: The FLIPAN Study. Nutrients. vol 14. issue 5. 2022-03-14. PMID:35268038. |
pa was a risk factor for ast (aspartate aminotransferase) (adjusted or: 7.26; 95% ci: 1.79−29.40) and a protective factor for alt (alanine aminotransferase) (adjusted or: 0.24; 95% ci: 0.12−0.48), ggt (gamma-glutamyl transferase) (adjusted or: 0.52; 95% ci: 0.29−0.94) and ifc-nmr (intrahepatic fat content by nuclear magnetic resonance) (adjusted or: 0.26; 95% ci: 0.12−0.56) when sociodemographic confounders were considered. |
2022-03-14 |
2023-08-16 |
human |
| Zhi-Mei Ma, Shang-Lei Lai, Jin-Yan Zhu, Qin-Chao Ding, Xiao-Bing Dou, Song-Tao L. [Atractylenolide Ⅰ improves acetaminophen-induced acute liver injury in mice by inhibiting MAPK/NF-κB signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 4. 2022-03-14. PMID:35285202. |
the protective effect of ao-Ⅰ against apap-induced ali was evaluated by detecting alanine aminotransferase(alt) and aspartate aminotransferase(ast) levels in the plasma and h&e staining in liver tissues of mice. |
2022-03-14 |
2023-08-13 |
mouse |
| Rehab F Abdel-Rahman, Hany M Fayed, Hanan A Ogaly, Rehab A Hussein, Mona Rasla. Phytoconstituents of Sansevieria suffruticosa N.E.Br. Leaves and its Hepatoprotective Effect via Activation of the NRF2/ARE Signaling Pathway in an Experimentally Induced Liver Fibrosis Rat Model. Chemistry & biodiversity. 2022-03-10. PMID:35266608. |
ssle treated groups exhibited a marked reduction in serum alanine transaminase (alt), aspartate transaminase (ast) and malondialdehyde (mda) levels compared with the taa group. |
2022-03-10 |
2023-08-13 |
rat |
| Angel Enrique Díaz Martínez, María José Alcaide Martín, Marcela González-Gros. Basal Values of Biochemical and Hematological Parameters in Elite Athletes. International journal of environmental research and public health. vol 19. issue 5. 2022-03-10. PMID:35270750. |
there were differences seen in the basal values of creatine kinase (ck), urea, creatinine, aspartate transaminase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), potassium, total bilirubin, and eosinophil percentage compared to reference population data. |
2022-03-10 |
2023-08-13 |
Not clear |
| Xin Liu, Haolu Wang, Xinyao Liu, Kim Bridle, Darrell Crawford, Xiaowen Lian. Efficacy and safety of immune-modulating therapy for primary sclerosing cholangitis: A systematic review and meta-analysis. Pharmacology & therapeutics. 2022-03-10. PMID:35271884. |
we performed a systematic review and meta-analysis to assess the efficacy and adverse effects of immunomodulators in adult patients with psc based on prognostic markers (alkaline phosphatase (alp) and total bilirubin), liver function marker (aspartate aminotransferase (ast)) and adverse event (ae) rates. |
2022-03-10 |
2023-08-13 |
Not clear |
| Yi-Liang Wang, Ying Zhang, Da-Sheng Ca. Hepatoprotective effects of sevoflurane against hepatic ischemia-reperfusion injury by regulating microRNA-124-3p-mediated TRAF3/CREB axis. Cell death discovery. vol 8. issue 1. 2022-03-09. PMID:35260558. |
in addition, mir-124-3p, traf3 and creb expression in hepatocytes was altered to identify their roles in modulating the levels of glutathione transferase (gst), aspartate aminotransferase (ast) and alanine aminotransferase (alt), and inflammation-related factors and hepatocyte apoptosis by elisa and flow cytometry respectively. |
2022-03-09 |
2023-08-13 |
mouse |
| Yu Ma, Siwen Li, Sixuan Tang, Shuzi Ye, Ningjuan Liang, Yuehui Liang, Fang Xia. Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway. Environmental science and pollution research international. 2022-03-08. PMID:35257348. |
in this study, our data clearly indicates that cr(vi) is capable of causing hepatocytes damage through the production of large amounts of reactive oxygen species (ros), causing an increase in aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2022-03-08 |
2023-08-13 |
human |
| Huan Wang, Yinzhu Jin, Yao Wang, Xuewei Wang, Wenhui Yu, Xiaowen Jian. Rotenone Induces Hepatotoxicity in Rats by Activating the Mitochondrial Pathway of Apoptosis. Toxicology mechanisms and methods. 2022-03-07. PMID:35253580. |
the results showed that rotenone significantly increased the hepatic index of rats and the activity of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in serum. |
2022-03-07 |
2023-08-13 |
rat |
| Leman Acun Delen, Zeliha Korkmaz Dişli, Hakan G Taş, Ufuk Kuyrukluyildiz, Gulce N Yazici, Bahadir Süleyman, Mehmet Kuzucu, Cebrail Gürsu, Halis Suleyma. The effects of thiamine pyrophosphate on propofol-induced oxidative liver injury and effect on dysfunction. General physiology and biophysics. vol 41. issue 1. 2022-03-07. PMID:35253651. |
total glutathione (tgsh), total oxidant (tos), and total antioxidant (tas) levels were tested together with aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh) and malondialdehyde (mda). |
2022-03-07 |
2023-08-13 |
rat |
| Juan Carlos Hernandez, Da-Wei Yeh, Joel Marh, Hye Yeon Choi, Julia Kim, Shefali Chopra, Li Ding, Matthew Thornton, Brendan Grubbs, Leonard Makowka, Linda Sher, Keigo Machid. Activated and nonactivated MSCs increase survival in humanized mice after acute liver injury through alcohol binging. Hepatology communications. 2022-03-05. PMID:35246968. |
blood samples were obtained at the end of the binge drinking and at the time of death to measure alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels. |
2022-03-05 |
2023-08-13 |
mouse |
| Shuai Wang, Xuemei Fan, Yang Gao, Lijuan Zuo, Mingqi Hong, Yan X. The Relationship Between Zinc Deficiency and Hepatocellular Carcinoma Associated with Hepatitis B Liver Cirrhosis: A 10-year Follow-up Study. Biological trace element research. 2022-03-05. PMID:35247138. |
compared with the non-zinc deficiency group, the zinc deficiency group is older, has a higher proportion of hepatic encephalopathy, higher levels of aspartate aminotransferase(ast), international normalized ratio(inr) and tb, and lower levels of cholinesterase (che), creatinine, and platelet counts (p< 0.05). |
2022-03-05 |
2023-08-13 |
Not clear |
| Pan Ke, Lirong Zhong, Wei Peng, Minzhi Xu, Jie Feng, Qingfeng Tian, Yan He, Rowan Dowling, Wenning Fu, Heng Jiang, Zhiguang Zhao, Kai Lu, Zuxun L. Association of the Serum transaminase with mortality among the United States elderly population. Journal of gastroenterology and hepatology. 2022-03-02. PMID:35233823. |
considering the inconsistent findings of research into the associations between serum levels of liver enzymes (aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyltransferase (ggt)) and mortality among elderly people, we aimed to investigate the associations of alt, ast, ggt and de-ritis ratio (drr, defined as ast/alt) and all-cause or cause-specific mortality among the us elderly people using national health and nutrition examination surveys (nhanes) data. |
2022-03-02 |
2023-08-13 |
Not clear |
| Wenbo Ding, Xiuwei Chen, Licheng Yang, Yaping Chen, Jie Song, Weiquan Bu, Bin Feng, Meng Zhang, Yi Luo, Xiaobin Jia, Liang Fen. Combination of ShuangDan Capsule and Sorafenib Inhibits Tumor Growth and Angiogenesis in Hepatocellular Carcinoma Via PI3K/Akt/mTORC1 Pathway. Integrative cancer therapies. vol 21. 2022-03-02. PMID:35234063. |
sorafenib monotherapy elicited hepatotoxicity for specific expression in the up-regulated level of aspartate transaminase (ast) and ast/glutamic-pyruvic transaminase (alt) ratio, but the co-administration could remedy this adverse effect. |
2022-03-02 |
2023-08-13 |
Not clear |
| Ikponmwosa Ojo, Augustine Apiamu, Egoamaka O Egbune, Nyerhovwo J Tonukar. Biochemical Characterization of Solid-State Fermented Cassava Stem (Manihot esculenta Crantz-MEC) and Its Application in Poultry Feed Formulation. Applied biochemistry and biotechnology. 2022-03-01. PMID:35230606. |
also, examination of alkaline phosphatase (alp) and alanine and aspartate aminotransferases (alt and ast) showed no marked difference in their activities for fermented feed at increasing inoculum sizes when compared with typical poultry feed, respectively (p > 0.05). |
2022-03-01 |
2023-08-13 |
Not clear |
| Ubaid Khan, Rana Uzair Ahmad, Zabeeh Ullah, Tooba Fida, Muhammad Shehrya. Parvovirus b19-Induced Acute Hepatitis With Hepatosplenomegaly and Polyarthropathy. Cureus. vol 14. issue 1. 2022-02-28. PMID:35223271. |
laboratory investigations showed highly elevated aspartate transaminase (ast), alanine transaminase (alt), and bilirubin. |
2022-02-28 |
2023-08-13 |
Not clear |
| Ali Khalifa, Laura Andreias, Sugirdhana Velpar. Adenovirus Hepatitis in Immunocompetent Adults. Journal of investigative medicine high impact case reports. vol 10. 2022-02-28. PMID:35225036. |
laboratory work was normal except for elevated liver function test (lft): alkaline phosphatase (ap) (296), aspartate transaminase (ast) (343), alanine transaminase (alt) (378), and international normalized ratio (inr) (1.23). |
2022-02-28 |
2023-08-13 |
Not clear |
| Sabit Cakmak, Anna Lukina, Subramanian Karthikeyan, Ella Atlas, Robert Dale. The association between blood PFAS concentrations and clinical biochemical measures of organ function and metabolism in participants of the Canadian Health Measures Survey (CHMS). The Science of the total environment. 2022-02-26. PMID:35218824. |
an increase in perfluorooctanoic acid (pfoa) equivalent to the magnitude of its geometric mean (gm) of 2.0 μg/l was associated with percentage (95% ci) increases in serum enzymes reflecting liver function: aspartate aminotransferase (ast) 3.7 (1.1, 6.4), gamma-glutamyl transferase (ggt) 11.8 (2.5, 21.8), alanine aminotransferase (alt) 3.2 (0.5, 5.9), and bilirubin 3.6 (2.7, 4.5). |
2022-02-26 |
2023-08-13 |
human |
| Petr Kelbich, Petr Vachata, Vilem Maly, Tomas Novotny, Jan Spicka, Inka Matuchova, Tomas Radovnicky, Ivan Stanek, Jan Kubalik, Ondrej Karpjuk, Frantisek Smisko, Eva Hanuljakova, Jan Krejse. Neutrophils in Extravascular Body Fluids: Cytological-Energy Analysis Enables Rapid, Reliable and Inexpensive Detection of Purulent Inflammation and Tissue Damage. Life (Basel, Switzerland). vol 12. issue 2. 2022-02-25. PMID:35207447. |
we assessed the relationships between percentages of neutrophils, aerobic and anaerobic metabolism, and tissue damage via the determination of aspartate aminotransferase catalytic activities (ast) in cerebrospinal fluid (csf), pleural effusions (pe), abdominal effusions (ae), and synovial fluids (sf). |
2022-02-25 |
2023-08-13 |
Not clear |
| Han Gyung Kim, Chaeyoung Lee, Ji Hye Yoon, Ji Hye Kim, Jae Youl Ch. BN82002 alleviated tissue damage of septic mice by reducing inflammatory response through inhibiting AKT2/NF-κB signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 148. 2022-02-24. PMID:35202908. |
lung edema and serum alanine transaminase (alt), aspartate transaminase (ast), tnf-α, il-1β, and nitric oxide (no) levels also were decreased by bn82002 (20 mg/kg). |
2022-02-24 |
2023-08-13 |
mouse |
| Kai Kang, Yunpeng Luo, Yang Gao, Jiannan Zhang, Changsong Wang, Dongsheng Fei, Wei Yang, Xianglin Meng, Ming Ye, Yan Gao, Haitao Liu, Xue Du, Yuanyuan Ji, Jieling Wei, Wanqiu Xie, Jun Wang, Mingyan Zhao, Kaijiang Y. Continuous Renal Replacement Therapy With oXiris Filter May Not be an Effective Resolution to Alleviate Cytokine Release Syndrome in Non-AKI Patients With Severe and Critical COVID-19. Frontiers in pharmacology. vol 13. 2022-02-21. PMID:35185571. |
clinical data, including the severity of covid-19 white blood cell count (wbc), neutrophil proportion (neut%), lymphocyte count (lymph), lymphocyte percentage (lym%), platelet (plt), c-reaction protein (crp), high sensitivity c-reactive protein (hs-crp), alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tb), albumin (alb), serum creatinine (scr), d-dimer, fibrinogen (fib), il-2, il-4, il-6, il-10, tnf-α, ifn-γ, number of hospital days and sequential organ failure assessment (sofa) score were obtained and collated from medical records, and then compared between the two groups. |
2022-02-21 |
2023-08-13 |
Not clear |