| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessia Dattilo, Giovanni Ceccarini, Gaia Scabia, Silvia Magno, Lara Quintino, Caterina Pelosini, Guido Salvetti, Roberto Cusano, Matteo Massidda, Lucia Montanelli, Donatella Gilio, Gianluca Gatti, Alessandro Giacomina, Mario Costa, Ferruccio Santini, Margherita Maffe. Circulating Levels of MiRNAs From 320 Family in Subjects With Lipodystrophy: Disclosing Novel Signatures of the Disease. Frontiers in endocrinology. vol 13. 2022-06-23. PMID:35733784. |
the hepatic enzymes gamma-glutamyl transferase (ggt), aspartate aminotransferase (ast), alanine aminotransferase (alt) and the marker of inflammation c-reactive protein (crp) were inversely related to cmir 320d (p < 0.05, for crp and ggt; p < 0.01, for ast and alt). |
2022-06-23 |
2023-08-14 |
human |
| Marta Moreno-Torres, Guillermo Quintás, José V Castel. The Potential Role of Metabolomics in Drug-Induced Liver Injury (DILI) Assessment. Metabolites. vol 12. issue 6. 2022-06-23. PMID:35736496. |
the current biochemical parameters for the detection of dili are based on enzymes (alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transpeptidase (ggt), alkaline phosphatase (alp)) and bilirubin serum levels that are not specific of dili and therefore there is an increasing interest on novel, specific, dili biomarkers discovery. |
2022-06-23 |
2023-08-14 |
Not clear |
| Min Li, Xueqin Wu, Jixing Zou, Yingqian Lai, Xiaotian Niu, Xiumei Chen, Yidi Kong, Guiqin Wan. Dietary α-lipoic acid alleviates deltamethrin-induced immunosuppression and oxidative stress in northern snakehead (Channa argus) via Nrf2/NF-κB signaling pathway. Fish & shellfish immunology. 2022-06-23. PMID:35738487. |
after the 28-day exposure test, we obtained the following results: i) α-la alleviates del-induced liver injury by reversing the increase of the serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels and liver cytochrome p450 enzymes (cytochrome p450 (cyp)1a and cyp1b) expression levels. |
2022-06-23 |
2023-08-14 |
cat |
| Shuang Wei, Ji Li, Dong-Wei Han, Qiang Fu, Feng Ha. [Mechanism of Astragali Radix-Puerariae Lobatae Radix combination in regulating type 2 diabetes mellitus through AMPK signaling pathway: based on network pharmacology and experimental verification]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 10. 2022-06-19. PMID:35718494. |
after 4 weeks of intragastric administration, serum fasting blood glucose(fbg), fasting insulin(fins), aspartate aminotransferase(ast), alanine aminotransferase(alt), triglyceride(tg), total cholesterol(tc), low-density lipoprotein cholesterol(ldl-c), high-density lipoprotein cholesterol(hdl-c), interleukin(il)-6, and tumor necrosis factor(tnf)-α of rats in each group were measured. |
2022-06-19 |
2023-08-14 |
rat |
| Wenwen Yang, Rui Guo, Aiwen Pi, Qinchao Ding, Liuyi Hao, Qing Song, Lin Chen, Xiaobing Dou, Lixin Na, Songtao L. Long noncoding RNA-EN_181 potentially contributes to the protective effects of N-acetylcysteine against non-alcoholic fatty liver disease in mice. The British journal of nutrition. 2022-06-16. PMID:35710106. |
after 14-week of intervention, nac obviously rescued the deleterious alterations induced by hfd, including the changes in body and liver weights, hepatic triglycerides (tgs), plasma alanine aminotransferase (alt), plasma aspartate transaminase (ast), and liver histomorphology (h&e and oil red o staining). |
2022-06-16 |
2023-08-14 |
mouse |
| I Tehseen, T U Haq, I Ilahi, A A Khan, M Attaullah, G Y Zamani, S Zaman, I Ismai. Antidiabetic and hepato-renal protective effects of medicinal plants in STZ induced diabetic rats. Brazilian journal of biology = Revista brasleira de biologia. vol 84. 2022-06-15. PMID:35703627. |
significant increase (< 0.05) was observed in the serum bilirubin, alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), urea and creatinine levels of diabetic control rat group. |
2022-06-15 |
2023-08-14 |
rat |
| Hua Wang, Chuan Jiang, Yakun Yang, Jinghan Li, Yihan Wang, Chaonan Wang, Yonggang Ga. Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis. PeerJ. vol 10. 2022-06-14. PMID:35698613. |
after seven weeks of res administration, serum alanine aminotransferase (alt), aspartate aminotransferase (ast) activities and liver hydroxyproline (hyp) levels were reduced; the malondialdehyde (mda) activities decreased and the levels of superoxide dismutase (sod) and glutathione (gsh) were raised. |
2022-06-14 |
2023-08-14 |
mouse |
| Nabil Mohamed Selim, Mina Michael Melk, Farouk Rasmy Melek, Dalia Osama Saleh, Mansour Sobeh, Seham S El-Hawar. Phytochemical profiling and anti-fibrotic activities of Plumbago indica L. and Plumbago auriculata Lam. in thioacetamide-induced liver fibrosis in rats. Scientific reports. vol 12. issue 1. 2022-06-14. PMID:35701526. |
alanine transaminase (alt), aspartate transaminase (ast), gamma glutamyl transferase and total bilirubin. |
2022-06-14 |
2023-08-14 |
rat |
| Yi-Hsieng Samuel Wu, Yi-Ling Lin, Wen-Yuan Yang, Sheng-Yao Wang, Yi-Chen Che. Pepsin-digested chicken-liver hydrolysate attenuates hepatosteatosis by relieving hepatic and peripheral insulin resistance in long-term high-fat dietary habit. Journal of food and drug analysis. vol 29. issue 2. 2022-06-13. PMID:35696203. |
elevated ( p < 0.05) serum aspartate aminotransferase (ast), alanine transaminase (alt), alkaline phosphatase (alp), free fatty acids (ffas), triglyceride (tg), total cholesterol (tc), and fasted glucose values in hfd-fed mice decreased ( p < 0.05) by supplementing clhs. |
2022-06-13 |
2023-08-14 |
mouse |
| Hongkang Zhu, Wenhao Jiang, Chang Liu, Cheng Wang, Bin Hu, Yahui Guo, Yuliang Cheng, He Qia. Ameliorative effects of chlorogenic acid on alcoholic liver injury in mice via gut microbiota informatics. European journal of pharmacology. 2022-06-13. PMID:35697148. |
experimental results showed the increased (p < 0.05) serum alanine aminotransferase (alt), aspartate aminotransferase (ast), low density lipoprotein (ldl), total cholesterol (tc) and triglyceride (tg) levels of mice fed with ethanol were ameliorated by supplementing with cga. |
2022-06-13 |
2023-08-14 |
mouse |
| Haitao Liu, Panpan Zhang, Xiaoxiao Ge, Qiong Wu, Chuchu Han, Linyang Zhang, Yuxin Hua, Yuxuan Zhang, Jiping Liu, Yongheng Shi, Bin Wang, Xiaoping Wang, Wei Wang, Yi Jiang, Huawei Zhang, Chong Deng, Yundong Xie, Ying Liu, Shipeng H. Optimization of clofibrate with O-desmethyl anetholtrithione lead to a novel hypolipidemia compound with hepatoprotective effect. Bioorganic & medicinal chemistry letters. 2022-06-13. PMID:35697180. |
the hepatic function indexes were also decreased, such as aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2022-06-13 |
2023-08-14 |
mouse |
| Jill M Larson-Peine, Meera C Heller, Abigail R Rathert-Williams, Kimberly A Pearl, Natalie B Duncan, Brian L Vander Ley, Allison M Meye. Blood chemistry and rectal temperature changes in a population of healthy, fall-born, suckling beef calves from birth to 72 h of age. Theriogenology. vol 188. 2022-06-11. PMID:35689944. |
serum magnesium, aspartate aminotransferase (ast), and total and direct bilirubin increased (p < 0.001) during the first 12 h, then decreased (p < 0.001) from 24 to 72 h. |
2022-06-11 |
2023-08-14 |
cattle |
| Yichun Tong, Caiyun Yu, Zechen Xie, Xianglei Zhang, Zaibin Yang, Tian Wan. Trans-anethole ameliorates lipopolysaccharide-induced acute liver inflammation in broilers via inhibiting NF-κB signaling pathway. Poultry science. vol 101. issue 8. 2022-06-11. PMID:35690001. |
however, compared with the control group, the lps group significantly increased (p < 0.01) the serum levels of interleukin-6 (il-6), interleukin-1beta (il-1β), tumor necrosis factor-alpha (tnf-α), alanine aminotransferase (alt) and aspartate aminotransferase (ast), and decreased (p < 0.01) the interleukin-10 (il-10) level. |
2022-06-11 |
2023-08-14 |
Not clear |
| Praveen Sharm. Value of Liver Function Tests in Cirrhosis. Journal of clinical and experimental hepatology. vol 12. issue 3. 2022-06-09. PMID:35677506. |
commonly available tests like serum bilirubin, liver enzymes (alanine [alt] and aspartate aminotransferase [ast], serum alkaline phosphatase [alp], gamma glutamyl transpeptidase [ggt]), serum albumin and prothrombin time for assessment of liver functions partly assess liver functions. |
2022-06-09 |
2023-08-14 |
Not clear |
| Vali Musazadeh, Neda Roshanravan, Parvin Dehghan, Sana Sedgh Ahrab. Effect of Probiotics on Liver Enzymes in Patients With Non-alcoholic Fatty Liver Disease: An Umbrella of Systematic Review and Meta-Analysis. Frontiers in nutrition. vol 9. 2022-06-09. PMID:35677540. |
all meta-analysis studies assessing the effect of probiotics on liver function tests [alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt)] were included. |
2022-06-09 |
2023-08-14 |
Not clear |
| S Malika, A Ullah, A A Anjum, M M K Sattar, T Ali, R Manzoo. Bio-efficacy of iron and zinc fortified wheat flour along with bio-assessment of its hepatic and renal toxic potential. Brazilian journal of biology = Revista brasleira de biologia. vol 82. 2022-06-08. PMID:35674594. |
liver biomarkers including alkaline phosphatase (alp), alanine transaminase (alt), aspartate aminotransferase (ast) and bilirubin were recorded from serum samples. |
2022-06-08 |
2023-08-14 |
rat |
| Sukrit Kanchanasurakit, Chayanis Kositamongkol, Kamonnat Lanoi, Monnaree Nunta, Thaksaporn Saetuan, Nathorn Chaiyakunapruk, Surasak Saokaew, Pochamana Phisalprap. Effects of Synbiotics, Probiotics, and Prebiotics on Liver Enzymes of Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Network Meta-Analysis. Frontiers in nutrition. vol 9. 2022-06-07. PMID:35669067. |
a systematic review and network meta-analysis was primarily conducted to compare the effects of synbiotics, probiotics, and prebiotics on aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2022-06-07 |
2023-08-14 |
Not clear |
| Omid Mehrpour, Christopher Hoyte, Foster Goss, Farshad M Shirazi, Samaneh Nakhae. Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases. Drug and chemical toxicology. 2022-06-07. PMID:35670081. |
our results showed that serum liver enzymes being present at elevated levels (alanine aminotransferase (alt), aspartate aminotransferase (ast) greater than 1000 u/l followed by alt, ast between 100 and 1000 u/l) , prothrombin time (pt) prolongation, bilirubin increase, renal failure, confusion, age, hypotension, other coagulopathy (such as partial thromboplastin time (ptt) prolongation), acidosis, and electrolyte abnormality were the effective factors in determining the outcomes in these patients. |
2022-06-07 |
2023-08-14 |
Not clear |
| Sanaa A Ahmed, Mahmoud H Abd El Reheem, Dalia A Elbah. l-Carnitine ameliorates the osteoporotic changes and protects against simvastatin induced myotoxicity and hepatotoxicity in glucocorticoid-induced osteoporosis in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-07. PMID:35671582. |
at the end of the experiment, serum calcium (ca), phosphorous (p), alkaline phosphatase (alp), osteoprotegerin (opg), total antioxidant (tao), creatine kinase (ck), alanine aminotransferase (alt), and aspartate aminotransferase (ast) levels were measured. |
2022-06-07 |
2023-08-14 |
rat |
| Jin-Ke Zhang, Xiu-Li Zhou, Xiao-Qian Wang, Jia-Xiong Zhang, Mei-Lian Yang, Ya-Ping Liu, Jian-Xin Cao, Gui-Guang Chen. Que Zui tea ameliorates hepatic lipid accumulation and oxidative stress in high fat diet induced nonalcoholic fatty liver disease. Food research international (Ottawa, Ont.). vol 156. 2022-06-02. PMID:35651050. |
furthermore, the contents of tc, tg, nefa, alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the liver tissues were inhibited after qw and qa administration. |
2022-06-02 |
2023-08-13 |
rat |