| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Özden Kutlay, Arzu Keskin Aktan, Esra Asla. The protective effect of apelin-13 on cardiorenal toxicity induced by cyclophosphamide. Canadian journal of physiology and pharmacology. 2022-02-16. PMID:34665971. |
lactate dehydrogenase, cardiac troponin i (ctni), creatine kinase mb (ck-mb), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), malondialdehyde, creatinine, and blood urea nitrogen were found to be high in the cyclophosphamide group; however, these values were reduced with apelin-13 administration. |
2022-02-16 |
2023-08-16 |
rat |
| Manal Abdul-Hamid, Eman Salah Abdel-Reheim, Walaa Hegazy, Ahmed Allam, Sarah I Othman, Maha Abdulla Alwaele, Samraa Hussein Abdel-Kaw. Effect of gervital in attenuating hepatotoxicity caused by methotrexate or azathioprine in adult albino rats. Environmental science and pollution research international. 2022-02-16. PMID:35169948. |
mtx and aza treatment decreased hb levels, increased relative liver weight, increased the activity of glutamate pyruvate transaminase (alt) and glutamate oxaloacetate transaminase (ast) aminotransferase (alt) and aspartate aminotransferase (ast) values, and displayed histopathological and ultrastructural alterations. |
2022-02-16 |
2023-08-13 |
rat |
| Bandana Kumari, Sadhana Sharma, Ramesh Kumar, Satish Dipankar, Bijaya N Naik, Ayan Banerjee, Sushil Kuma. Efficacy of Lipid Ratios and Platelet Distribution Width for Assessment of Liver Fibrosis in Patients With Non-alcoholic Fatty Liver Disease. Cureus. vol 14. issue 1. 2022-02-15. PMID:35165568. |
mean values of alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), triglyceride (tg), triglyceride/high-density lipoprotein (tg/hdl) ratio, total cholesterol/high-density lipoprotein (tc/hdl) ratio, and platelet distribution width (pdw) were significantly higher in patients with af (group ii), while platelet count (pc) was significantly lower in group ii. |
2022-02-15 |
2023-08-13 |
Not clear |
| Sarfraz Ahmed, Najeeb Ullah, Sadia Parveen, Ifra Javed, Nur Asyilla Che Jalil, Mogana Das Murtey, Irfan Shahzad Sheikh, Shahroz Khan, Suvash Chandra Ojha, Ke Che. Effect of Silymarin as an Adjunct Therapy in Combination with Sofosbuvir and Ribavirin in Hepatitis C Patients: A Miniature Clinical Trial. Oxidative medicine and cellular longevity. vol 2022. 2022-02-14. PMID:35154575. |
the effect of daas along with silymarin was also examined on variable sex hormone level and liver function markers such as alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), and bilirubin. |
2022-02-14 |
2023-08-13 |
Not clear |
| Asghar Ghahri, Mohammad Hossien Dehghan, Pouria Seydi, Sara Mashayekhi, Yasaman Naderi, Enayatollah Seyd. The perchloroethylene-induced toxicity in dry cleaning workers lymphocytes through induction of oxidative stress. Journal of biochemical and molecular toxicology. 2022-02-14. PMID:35156261. |
blood samples were evaluated for liver (alanine transaminase [alt] and aspartate transaminase [ast]) and kidney (bun and creatinine) markers. |
2022-02-14 |
2023-08-13 |
Not clear |
| Sumit Rungta, Shweta Kumari, Amar Deep, Kamlendra Verma, Suchit Swaroo. APRI and FIB-4 performance to assess liver fibrosis against predefined Fibroscan values in chronic hepatitis C virus infection. Journal of family medicine and primary care. vol 10. issue 11. 2022-02-09. PMID:35136771. |
there are some noninvasive methods such as fibroscan that are now the investigation of choice; fib-4 and aminotransferase to platelet ratio index (apri) are other noninvasive tools to assess liver fibrosis by using aspartate aminotransferase (ast), alanine aminotransferase (alt), platelet count, and age. |
2022-02-09 |
2023-08-13 |
Not clear |
| M A Buabeid, E-S A Arafa, T Rani, F U D Ahmad, H Ahmed, W Hassan, G Murtaz. Effects of Solanum lycopersicum L. (tomato) against isoniazid and rifampicin induced hepatotoxicity in wistar albino rats. Brazilian journal of biology = Revista brasleira de biologia. vol 84. 2022-02-09. PMID:35137848. |
hepatotoxicity induced by inh+rif resulted in significant elevation of serum hepatic enzymes including aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and total bilirubin while decreased the albumin level. |
2022-02-09 |
2023-08-13 |
rat |
| Rana Toghan, Yahia A Amin, Rana A Ali, Samer S Fouad, Maha Abd-El Baky Ahmed, Shaimaa M M Sale. Protective effects of Folic acid against reproductive, hematological, hepatic, and renal toxicity induced by Acetamiprid in male Albino rats. Toxicology. 2022-02-06. PMID:35124148. |
significant increases in the levels of hepatic markers enzymes (aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp) in acetamiprid treated group, as well as severe toxic effect was found on the liver and kidney after acetamiprid delivery according to the histopathological examinations which were confirmed after applying histological, histochemical, and immunohistochemistry tests. |
2022-02-06 |
2023-08-13 |
rat |
| Yvonne Huber, Andreas Schulz, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Thomas Münzel, Peter R Galle, Philipp S Wild, Karl J Lackner, Jörn M Schattenber. Prevalence and Risk Factors of Advanced Liver Fibrosis in a Population-Based Study in Germany. Hepatology communications. 2022-02-05. PMID:35122404. |
the distribution of alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyltransferase (ggt), fatty liver index (fli), and fibrosis-4 (fib-4) score, as well as the underlying risk factors, were assessed by regression models. |
2022-02-05 |
2023-08-13 |
human |
| Hanaa Mohamed Khalaf, Sara Mohamed Naguib Abdel Hafez, Ahlam Mohamed Abdalla, Nermeen N Welson, Walaa Yehia Abdelzaher, Fatma Alzhraa Fouad Abdelbak. Role of Platelet-activating factor and HO-1 in mediating the protective effect of rupatadine against 5-fluorouracil-induced hepatotoxicity in rats. Environmental science and pollution research international. 2022-02-04. PMID:35119631. |
hepatic toxicity was assessed by measuring both liver and body weights, serum alanine aminotransferase and aspartate aminotransferase (alt and ast), hepatic oxidative stress parameters (malondialdehyde (mda), nitric oxide levels (nox), reduced glutathione (gsh), superoxide dismutase (sod)), and heme oxygenase-1 (ho-1). |
2022-02-04 |
2023-08-13 |
rat |
| Zining Xu, Zhenkun Weng, Jingjia Liang, Qian Liu, Xin Zhang, Jin Xu, Cheng Xu, Aihua G. Association between urinary cadmium concentrations and liver function in adolescents. Environmental science and pollution research international. 2022-02-03. PMID:35113370. |
liver function was indicated by the levels of alanine aminotransferase (alt) and aspartate amino transferase (ast). |
2022-02-03 |
2023-08-13 |
Not clear |
| Chike Chiejina, Lucy Anih, Charles Okoye, Ifeanyi Oscar Aguzie, Daoud Ali, Gokhlesh Kumar, Christopher Didigwu Nwan. Haloperidol alters the behavioral, hematological and biochemical parameters of freshwater African catfish, Clarias gariepinus (Burchell 1822). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2022-02-03. PMID:35114394. |
the activities of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and acid phosphatase (acp); and serum creatinine, bile acid and bilirubin were increased on 15-day exposure to the drug. |
2022-02-03 |
2023-08-13 |
Not clear |
| Mehnoosh Samadi, Mehdi Moradinazar, Tina Khosravy, Davood Soleimani, Parvin Jahangiri, Negin Kamar. A systematic review and meta-analysis of preclinical and clinical studies on the efficacy of ginger for the treatment of fatty liver disease. Phytotherapy research : PTR. 2022-02-02. PMID:35106852. |
the present study provides comprehensive evidence of the efficacy of ginger to improve the liver levels of cholesterol (-5.60 mg/g), triglycerides (tg, -4.28 mg/g), malondialdehyde (-3.16 nmol/mg), catalase (cat) (3.35 nmol/mg), superoxide dismutase (sod, 3.01 u/mg), serum levels of alanine aminotransferase (alt, -2.85 u/l), aspartate aminotransferase (ast, -0.98 u/l), tg (-4.98 mg/dl), low-density lipoprotein (ldl, -3.94 mg/dl), total cholesterol (tc, -3.45 mg/dl), high-density lipoprotein (hdl, 1.27 mg/dl), and fasting blood sugar (fbs, -2.54 mg/dl). |
2022-02-02 |
2023-08-13 |
cat |
| Jiafeng Xia, Longxian Lv, Boqiang Liu, Shuting Wang, Sitong Zhang, Zhengjie Wu, Liya Yang, Xiaoyuan Bian, Qiangqiang Wang, Kaicen Wang, Aoxiang Zhuge, Shengjie Li, Ren Yan, Huiyong Jiang, Kaijin Xu, Lanjuan L. Akkermansia muciniphila Ameliorates Acetaminophen-Induced Liver Injury by Regulating Gut Microbial Composition and Metabolism. Microbiology spectrum. 2022-02-02. PMID:35107323. |
administration of a. muciniphila efficiently alleviated apap-induced hepatotoxicity and reduced the levels of serum alanine aminotransferase (alt) and aspartate transaminase (ast). |
2022-02-02 |
2023-08-13 |
Not clear |
| Faezeh Darabi, Majid Keshavarzi, Media N Abdullah, Fatemeh Dehghani, Narges Khanjani, Saeed Yousefinejad, Farahnaz Khajehnasiri, Zahra Zamania. Evaluation of oxidative stress and biochemical biomarkers, and psychological parameters in cement plant workers. Toxicology and industrial health. vol 38. issue 1. 2022-02-01. PMID:35100896. |
the levels of alkaline phosphatase (alp), aspartate transaminase (ast), and the scores of depression and stress were also significantly higher in the exposed group. |
2022-02-01 |
2023-08-13 |
human |
| Fenglian Yan, Dalei Cheng, Haiyan Wang, Min Gao, Junfeng Zhang, Hongyan Cheng, Changying Wang, Hui Zhang, Huabao Xion. Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization. Frontiers in immunology. vol 12. 2022-01-31. PMID:35095894. |
herein, mice were administered corilagin (25 mg/kg) intraperitoneally twice at 12 h intervals, and 1 h later, the mice were challenged with con a (20 mg/kg body weight); serum and liver samples were collected after 12 h. the results showed that corilagin significantly increased the survival of mice and reduced serum alanine transaminase (alt) and aspartate aminotransferase (ast) levels. |
2022-01-31 |
2023-08-13 |
mouse |
| Bin Wang, Jihua Xu, Shenhui Jiang, Yanbo Wang, Jun Zhu, Yugang Zhan. Combined Analysis of Gut Microbiota and Plasma Metabolites Reveals the Effect of Red-Fleshed Apple Anthocyanin Extract on Dysfunction of Mice Reproductive System Induced by Busulfan. Frontiers in nutrition. vol 8. 2022-01-31. PMID:35096946. |
compared with ba0 (busulfan without raae) group, total antioxidant capacity(t-aoc) and the activity of superoxide dismutase (sod) and glutathione catalase (gsh-px) in raae treatment groups were obviously increased, while the activity of alanine aminotransferase (alt) and aspartate aminotransferase (ast) were significantly decreased. |
2022-01-31 |
2023-08-13 |
mouse |
| Amin Gheshlaghi-Ghadim, Vahid Mohammadi, Elham Zadeh-Hashe. Protective Effects of Quercetin on Clothianidin-Induced Liver Damage in the Rat Model. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-01-28. PMID:35087597. |
enzyme activity, including alanine aminotransferase (alt) and aspartate aminotransferase (ast), was measured by spectrophotometry in serum samples by an automatic biochemical analyzer using commercial kits. |
2022-01-28 |
2023-08-13 |
rat |
| Songming Ding, Weilin Wu, Jianfang Lu, Hengkai Zhu, Shusen Zheng, Qiyong L. Migration of fully covered self-expandable metallic stents used to treat anastomotic strictures after orthotopic liver transplantation: A single-center, retrospective analysis. Medicine. vol 101. issue 4. 2022-01-28. PMID:35089220. |
the effects of age, gender, albumin, alanine aminotransferase, aspartate aminotransferase (ast), γ-glutamyl transpeptidase, alkaline phosphatase, total bilirubin, direct bilirubin, abo (blood group system consists of four antigens) incompatibility, stricture length, fcem brand, fcem length, donor liver and recipient bile duct diameters, size mismatches between the donor and recipient bile ducts >2 mm, diabetes and/or hypertension status, endoscopic sphincterotomy status, the use of plastic stents or nasobiliary drainage prior to fcem implantation, duration from olt to fcem placement, and olt etiology on fcem migration were retrospectively analyzed.the fcem migration rate was 48.8% (21/43) at 6 months. |
2022-01-28 |
2023-08-13 |
Not clear |
| b' Aynur Atilla, Mehmet H Ta\\xc5\\x9fk\\xc4\\xb1n, Z\\xc3\\xbclay Kazak, Saliha Ayd\\xc4\\xb1n, S S\\xc4\\xb1rr\\xc4\\xb1 K\\xc4\\xb1l\\xc4\\xb1\\xc3\\xa. GP73 level in patients with chronic hepatitis B: Relationship with liver biopsy, levels of ALT, AST and HBV DNA. Indian journal of pathology & microbiology. vol 65. issue 1. 2022-01-25. PMID:35074966.' |
in this study, we investigated the golgi protein 73 (gp73) level in hepatitis b and determined the correlation between hepatitis b virus (hbv) dna, alanine aminotransferase (alt), aspartate aminotransferase (ast) levels, and liver histopathology. |
2022-01-25 |
2023-08-13 |
Not clear |