| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Bianchi, T Sharp, J P Bolam, L Della Cort. The effect of kainic acid on the release of GABA in rat neostriatum and substantia nigra. Neuroreport. vol 5. issue 10. 1994-11-10. PMID:7919172. |
it is concluded that excitatory amino acid receptor stimulation of the neostriatum releases gaba from striatonigral neurones and that stimulation of the substantia nigra causes the release from striatonigral terminals and/or the collaterals of nigrofugal neurones. |
1994-11-10 |
2023-08-12 |
rat |
| S Goto, K Yamada, N Inoue, S Nagahiro, Y Ushi. Increased expression of growth-associated protein GAP-43/B-50 following cerebral hemitransection or striatal ischemic injury in the substantia nigra of adult rats. Brain research. vol 647. issue 2. 1994-11-10. PMID:7922508. |
the substantia nigra receives massive inhibitory gamma-aminobutyric acid (gaba)-ergic inputs, deafferentation of which is supposed to lead to anterograde transsynaptic regression of the nigral neurons. |
1994-11-10 |
2023-08-12 |
rat |
| M Sieklucka, W Löscher, C Heim, K H Sonta. Influence of short-lasting bilateral clamping of carotid arteries (BCCA) on GABA turnover in rat brain structures. Neurochemical research. vol 19. issue 3. 1994-06-06. PMID:8177378. |
fourteen days after bcca, gaba turnover was significantly increased in hippocampus, substantia nigra and cortex, but not different from sham-operated controls in several other brain regions, including striatum, hypothalamus and cerebellum. |
1994-06-06 |
2023-08-12 |
rat |
| N Garcia-Cairasco, V C Terra, M C Dorett. Midbrain substrates of audiogenic seizures in rats. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136050. |
based upon selective lesion and microinjection (gaba, clobazam, nmda) studies of substantia nigra (sn), inferior colliculus (ic), superior colliculus (sc), and on specific knife cuts at midcollicular levels, we have suggested differential roles for these substrates in the origin and spreading of as. |
1994-04-25 |
2023-08-12 |
rat |
| Q Y L. [Effects of GABA and substance P on metabolism of striatal dopamine following experimental cerebral ischemia]. Zhonghua yi xue za zhi. vol 73. issue 11. 1994-04-12. PMID:7510213. |
the above effects of intrastriatal bic on da and its metabolites were completely reversed with an intranigral injection of 5 nmol of substance p. it is suggested that the effect of intrastriatal bic on da metabolites in the striatum is mediated by substance p in the substantia nigra and that the regulatory effect of gaba and sp on striatal da is working in middle cerebral artery occlusion. |
1994-04-12 |
2023-08-12 |
rat |
| M Pérez de la Mora, A M Hernandez-Gómez, J Méndez-Franco, K Fux. Cholecystokinin-8 increases K(+)-evoked [3H] gamma-aminobutyric acid release in slices from various brain areas. European journal of pharmacology. vol 250. issue 3. 1994-03-31. PMID:8112402. |
while the basal release of [3h]gaba was not affected by cck-8, the k(+)-stimulated release of [3h]gaba was significantly enhanced by 300 nm of cck-8 in the caudate putamen, the substantia nigra, the hippocampal formation and the parietofrontal cortex. |
1994-03-31 |
2023-08-12 |
rat |
| R Wolf, U Tschern. Valproate effect on gamma-aminobutyric acid release in pars reticulata of substantia nigra: combination of push-pull perfusion and fluorescence histochemistry. Epilepsia. vol 35. issue 1. 1994-03-25. PMID:8112252. |
valproate effect on gamma-aminobutyric acid release in pars reticulata of substantia nigra: combination of push-pull perfusion and fluorescence histochemistry. |
1994-03-25 |
2023-08-12 |
rat |
| R Wolf, U Tschern. Valproate effect on gamma-aminobutyric acid release in pars reticulata of substantia nigra: combination of push-pull perfusion and fluorescence histochemistry. Epilepsia. vol 35. issue 1. 1994-03-25. PMID:8112252. |
to study further the previously demonstrated suppressive in vivo effect of sodium valproate (vpa) on gamma-aminobutyric acid (gaba) release in the preoptic area, we examined gaba neurotransmission in substantia nigra (sn), using the push-pull cannula technique in freely moving ovariectomized rats. |
1994-03-25 |
2023-08-12 |
rat |
| V Steffen, M L Vizuete, A Machado, J Can. The effect of a vitamin E-deficient diet on amino acid levels in the substantia nigra, striatum and hippocampus of rats. Life sciences. vol 54. issue 5. 1994-02-18. PMID:8289599. |
the substantia nigra showed an increase in glutamate and gaba and a decrease of tryptophan concentration compared with controls. |
1994-02-18 |
2023-08-12 |
rat |
| H Zhang, X Weng, H C Rosenber. Characterization of substantia nigra pars reticulata neurons based on response to iontophoretically applied GABA and flurazepam. Life sciences. vol 53. issue 25. 1994-01-10. PMID:8255152. |
previous work had suggested that neurons in the pars reticulata of the substantia nigra (snpr) might be differentiated based on responsiveness to gaba and benzodiazepines (bzs). |
1994-01-10 |
2023-08-12 |
rat |
| b' D S Garant, S G Xu, E F Sperber, S L Mosh\\xc3\\xa. The influence of thalamic GABA transmission on the susceptibility of adult rats to flurothyl induced seizures. Epilepsy research. vol 15. issue 3. 1993-12-06. PMID:8223414.' |
we hypothesize that gaba synapses in po may be part of a seizure propagation or control circuit including striatum, substantia nigra, and superior colliculus. |
1993-12-06 |
2023-08-12 |
rat |
| S O Ogren, B Pak. Effects of dopamine D1 and D2 receptor agonists and antagonists on seizures induced by chemoconvulsants in mice. Pharmacology & toxicology. vol 72. issue 4-5. 1993-10-12. PMID:8103921. |
stimulation of dopamine d1 receptors can reduce seizure activity caused by gaba receptor blockade possibly by facilitation of gaba transmission in the striatum and substantia nigra. |
1993-10-12 |
2023-08-12 |
mouse |
| B Glenthøj, R Hemmingsen, D I Barry, P Allerup, T Bruhn, T G Bolwi. Electrical kindling of rats treated discontinuously or continuously with haloperidol. European journal of pharmacology. vol 236. issue 3. 1993-09-30. PMID:8359198. |
we suggest that depressed gamma-aminobutyric acid activity in substantia nigra could be a common mechanism. |
1993-09-30 |
2023-08-12 |
rat |
| E Molina-Holgado, K M Dewar, L Grondin, N M van Gelder, T A Reade. Changes of amino acid and monoamine levels after neonatal 6-hydroxydopamine denervation in rat basal ganglia, substantia nigra, and Raphe nuclei. Journal of neuroscience research. vol 35. issue 4. 1993-09-30. PMID:8360949. |
in the substantia nigra only increases in taurine, gaba, glutamic acid, and glutamine could be documented. |
1993-09-30 |
2023-08-12 |
rat |
| W Lösche. Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8097295. |
as shown in this review, there is substantial evidence that valproate increases gaba turnover and thereby potentiates gabaergic functions in some specific brain regions, such as substantia nigra, thought to be involved in the control of seizure generation and propagation. |
1993-05-19 |
2023-08-12 |
Not clear |
| C G Wasterlain, C F Baxter, R A Baldwi. GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8474571. |
gaba metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. |
1993-05-19 |
2023-08-12 |
rat |
| C G Wasterlain, C F Baxter, R A Baldwi. GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8474571. |
the metabolism of gaba and other amino acids was studied in the substantia nigra, the hippocampus and the parietal cortex of rats following microinjections of gamma-vinyl-gaba during status epilepticus induced by lithium and pilocarpine. |
1993-05-19 |
2023-08-12 |
rat |
| C G Wasterlain, C F Baxter, R A Baldwi. GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8474571. |
in controls, both gaba concentration and rate of gaba synthesis were highest in the substantia nigra and lowest in cortex, as expected. |
1993-05-19 |
2023-08-12 |
rat |
| C G Wasterlain, C F Baxter, R A Baldwi. GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8474571. |
in substantia nigra, status epilepticus resulted in a 2 1/2 fold decline in the rate of gaba synthesis and in a 307% increase in the turnover time of the gaba pool. |
1993-05-19 |
2023-08-12 |
rat |
| C G Wasterlain, C F Baxter, R A Baldwi. GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8474571. |
these data suggest that the observed reduction of the rate of gaba synthesis in substantia nigra could play a key role in seizure spread in this model of status epilepticus. |
1993-05-19 |
2023-08-12 |
rat |