| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Morari, W T O'Connor, M Darvelid, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--I. Effects of perfusion with tetrodotoxin and low-calcium medium. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730707. |
perfusion with a low-ca2+ (0.1 mm) medium and with the voltage-dependent na(+)-channel blocker tetrodotoxin (10 microm) was alternatively performed in both brain regions and the dialysate dopamine, glutamate and gaba levels were simultaneously measured in the dorsolateral striatum, whereas gaba levels alone were monitored in the substantia nigra. |
1996-10-24 |
2023-08-12 |
rat |
| M Morari, W T O'Connor, M Darvelid, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--I. Effects of perfusion with tetrodotoxin and low-calcium medium. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730707. |
neither of these intrastriatal treatments significantly affected gaba levels in the substantia nigra. |
1996-10-24 |
2023-08-12 |
rat |
| b' G G Cobos-Zapiain, R Salado-Castillo, M S\\xc3\\xa1nchez-Alavez, G L Quirarte, G Rold\\xc3\\xa1n-Rold\\xc3\\xa1n, M A D\\xc3\\xadaz del Guante, R A Prado-Alcal\\xc3\\xa. High level of footshock during inhibitory avoidance training prevents amnesia induced by intranigral injection of GABA antagonists. Neurobiology of learning and memory. vol 65. issue 3. 1996-06-12. PMID:8616583.' |
since there is a close anatomical and functional relationship between the neostriatum and the substantia nigra, it was of interest to determine whether enhanced training with a high level of footshock would prevent the reported amnesic state induced by injections of gaba antagonists into the latter structure. |
1996-06-12 |
2023-08-12 |
rat |
| J Aceves, B Floran, A Sierra, S Marisca. D-1 receptor mediated modulation of the release of gamma-aminobutyric acid by endogenous dopamine in the basal ganglia of the rat. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 5. 1996-02-07. PMID:8539416. |
the results indicate that endogenous dopamine enhances gaba release from striatal terminals in the pars reticulata of the substantia nigra, entopeduncular nucleus and caudate-putamen. |
1996-02-07 |
2023-08-12 |
rat |
| C S Biggs, L J Fowler, P S Whitton, M S Star. Impulse-dependent and tetrodotoxin-sensitive release of GABA in the rat's substantia nigra measured by microdialysis. Brain research. vol 684. issue 2. 1995-11-24. PMID:7583219. |
impulse-dependent and tetrodotoxin-sensitive release of gaba in the rat's substantia nigra measured by microdialysis. |
1995-11-24 |
2023-08-12 |
rat |
| M A Hossain, N Weine. Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562556. |
we have evaluated (a) the effects of dopamine (da) denervation on gamma-aminobutyric acid (gaba) turnover in terms of in vivo rate of gaba synthesis; (b) effects of da d1 and d2 receptor agonists and antagonists on the in vivo gaba synthesis rate; and (c) the effects of gabaa and gabab receptor agonists and antagonists on the intracellular accumulation of camp in the ipsi- and contralateral striatum and substantia nigra of rats after unilateral 6-hydroxydopamine-induced lesions of the nigrostriatal da system (da depletion > 90%). |
1995-11-21 |
2023-08-12 |
rat |
| M A Hossain, N Weine. Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562556. |
we observed that the in vivo rate of gaba synthesis remained unaffected when the da levels were depleted by 95% and 50% in the ipsilateral striatum and substantia nigra, respectively, compared with the contralateral intact side. |
1995-11-21 |
2023-08-12 |
rat |
| M A Hossain, N Weine. Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562556. |
the da d2 agonist quinpirole (1.0 mg/kg) significantly decreased the rate of gaba formation in the ipsi- and contralateral striatum and substantia nigra. |
1995-11-21 |
2023-08-12 |
rat |
| M A Hossain, N Weine. Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562556. |
in contrast, the d2 antagonist (+/-)-sulpiride (25.0 mg/kg) augmented the rate of gaba formation in the da-denervated and intact striatum and substantia nigra. |
1995-11-21 |
2023-08-12 |
rat |
| b' M E Ch\\xc3\\xa1vez, R Salado-Castillo, M S\\xc3\\xa1nchez-Alavez, G L Quirarte, R A Prado-Alcal\\xc3\\xa. Post-training injection of GABAergic antagonists into the striatum produces retrograde amnesia. Neurobiology of learning and memory. vol 63. issue 3. 1995-10-19. PMID:7670844.' |
we now report that in the wistar rat, intrastriatal post-training injection of microgram quantities of bicuculine or picrotoxin, two gaba antagonists with different modes of action, induced retrograde amnesia of inhibitory avoidance, in concordance with the effects of injections of picrotoxin into the substantia nigra. |
1995-10-19 |
2023-08-12 |
rat |
| L F Nicholson, R L Faull, H J Waldvogel, M Draguno. GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644016. |
gaba and gabaa receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble huntington's disease. |
1995-09-21 |
2023-08-12 |
rat |
| L F Nicholson, R L Faull, H J Waldvogel, M Draguno. GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644016. |
gaba and gabaa receptors have been studied in the substantia nigra of the rat following quinolinic acid lesions in the striatum. |
1995-09-21 |
2023-08-12 |
rat |
| L F Nicholson, R L Faull, H J Waldvogel, M Draguno. GABA and GABAA receptor changes in the substantia nigra of the rat following quinolinic acid lesions in the striatum closely resemble Huntington's disease. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644016. |
the results showed that in the normal substantia nigra gaba and gabaa receptors were mainly localized within the pars reticulata. |
1995-09-21 |
2023-08-12 |
rat |
| B K Yamamoto, J F Nash, G A Gudelsk. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791076. |
modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. |
1995-07-21 |
2023-08-12 |
rat |
| B K Yamamoto, J F Nash, G A Gudelsk. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791076. |
the effects of the amphetamine analog, 3,4-methylenedioxymethamphetamine (mdma) were compared to the effects of d-amphetamine on the in vivo release of dopamine and gamma-aminobutyric acid (gaba) in the striatum and substantia nigra. |
1995-07-21 |
2023-08-12 |
rat |
| B K Yamamoto, J F Nash, G A Gudelsk. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791076. |
the brain region-dependent role of the 5-ht2 receptors in the striatum and substantia nigra in regulating mdma-induced dopamine and gaba release also was studied. |
1995-07-21 |
2023-08-12 |
rat |
| B K Yamamoto, J F Nash, G A Gudelsk. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791076. |
at the doses used in this study, mdma but not d-amphetamine increased the extracellular concentrations of 5-ht and decreased gaba efflux in the substantia nigra. |
1995-07-21 |
2023-08-12 |
rat |
| B K Yamamoto, J F Nash, G A Gudelsk. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791076. |
the ability of mdma to decrease nigral gaba efflux also was blocked by the local infusion of ritanserin into either the substantia nigra or the striatum. |
1995-07-21 |
2023-08-12 |
rat |
| M J During, P Leone, K E Davis, D Kerr, R S Sherwi. Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels. The Journal of clinical investigation. vol 95. issue 5. 1995-06-05. PMID:7738204. |
glucose modulates rat substantia nigra gaba release in vivo via atp-sensitive potassium channels. |
1995-06-05 |
2023-08-12 |
rat |
| U Sayin, W Timmerman, B H Westerin. The significance of extracellular GABA in the substantia nigra of the rat during seizures and anticonvulsant treatments. Brain research. vol 669. issue 1. 1995-05-12. PMID:7712166. |
the significance of extracellular gaba in the substantia nigra of the rat during seizures and anticonvulsant treatments. |
1995-05-12 |
2023-08-12 |
rat |