| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Moukhles, O Bosler, J P Bolam, A Vallée, D Umbriaco, M Geffard, G Douce. Quantitative and morphometric data indicate precise cellular interactions between serotonin terminals and postsynaptic targets in rat substantia nigra. Neuroscience. vol 76. issue 4. 1997-04-29. PMID:9027876. |
they indicate that this dense serotonin input to the substantia nigra is very precisely organized, acting through both "non-junctional" and "junctional" modes of neurotransmission in the pars compacta, which projects to the neostriatum and the limbic system, whereas the predominant mode of serotonin transmission appears to be of the "junctional" type in the pars reticulata, where serotonin can finely control the motor output of the basal ganglia by acting on the gaba projection neurons either directly or through the local release of dopamine by dopaminergic dendrites. |
1997-04-29 |
2023-08-12 |
rat |
| A A Dunn-Meynell, V H Routh, J J McArdle, B E Levi. Low-affinity sulfonylurea binding sites reside on neuronal cell bodies in the brain. Brain research. vol 745. issue 1-2. 1997-04-29. PMID:9037388. |
high-affinity sulfonylurea binding sites are concentrated in areas such as the substantia nigra (sn) where glucose and sulfonylureas increase transmitter release from gaba neurons. |
1997-04-29 |
2023-08-12 |
Not clear |
| Z B You, A Saria, R Fischer-Colbrie, L Terenius, M Goiny, M Herrera-Marschit. Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971731. |
in vivo microdialysis was used to study the effect of secretogranin ii-derived peptides on dynorphin b (dyn b), dopamine, gamma-aminobutyric acid (gaba), glutamate and aspartate release in the substantia nigra and neostriatum of halothane-anaesthesized rats. |
1997-04-02 |
2023-08-12 |
rat |
| Z B You, A Saria, R Fischer-Colbrie, L Terenius, M Goiny, M Herrera-Marschit. Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971731. |
in the substantia nigra, local infusion of secretoneurin (secretogranin ii 154-186) (1-50 microm) increased, in a concentration-dependent manner, extracellular aspartate, glutamate, dyn b, dopamine and gaba levels. |
1997-04-02 |
2023-08-12 |
rat |
| Z B You, A Saria, R Fischer-Colbrie, L Terenius, M Goiny, M Herrera-Marschit. Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971731. |
in the neostriatum, dyn b, glutamate, aspartate and gaba levels were also increased by local secretoneurin infusion, but the effect was less prominent than in the substantia nigra. |
1997-04-02 |
2023-08-12 |
rat |
| Z B You, A Saria, R Fischer-Colbrie, L Terenius, M Goiny, M Herrera-Marschit. Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971731. |
in the substantia nigra, only dyn b levels were significantly increased following infusion of 10 microm of the secretoneurin-c terminal (secretoneurin-15c), whereas dyn b and gaba levels were increased by the same concentration of the secretogranin ii c terminus (ym). |
1997-04-02 |
2023-08-12 |
rat |
| G L Holme. Epilepsy in the developing brain: lessons from the laboratory and clinic. Epilepsia. vol 38. issue 1. 1997-02-27. PMID:9024181. |
there are also age-related differences in response to gaba agonists and antagonists in the substantia nigra, a structure important in the propagation of seizures. |
1997-02-27 |
2023-08-12 |
rat |
| T J Tersigni, H C Rosenber. Local pressure application of cannabinoid agonists increases spontaneous activity of rat substantia nigra pars reticulata neurons without affecting response to iontophoretically-applied GABA. Brain research. vol 733. issue 2. 1997-02-06. PMID:8891301. |
this study tested the hypothesis that cannabinoid agonists, applied locally into the pars reticulata of substantia nigra (snpr), could modulate striatonigral transmission, without affecting the response of snpr neurons to iontophoretically-applied gaba. |
1997-02-06 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, E Pettersson, I Nylander, M Goiny, H Z Shou, J Kehr, O Godukhin, T Hökfelt, L Terenius, U Ungersted. Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884775. |
the effect of cholecystokinin peptides on the release of dynorphin b, aspartate, glutamate, dopamine and gaba in the neostriatum and substantia nigra of the rat was investigated using in vivo microdialysis. |
1997-01-30 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, E Pettersson, I Nylander, M Goiny, H Z Shou, J Kehr, O Godukhin, T Hökfelt, L Terenius, U Ungersted. Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884775. |
basal extracellular gaba levels were increased significantly in both the neostriatum and substantia nigra ipsilateral to the lesion. |
1997-01-30 |
2023-08-12 |
rat |
| W Sommer, R Rimondini, W O'Connor, A C Hansson, U Ungerstedt, K Fux. Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 24. 1997-01-16. PMID:8943073. |
dual probe in vivo microdialysis was used to investigate gamma-aminobutyric acid (gaba) release in the substantia nigra and the globus pallidus, which represent the terminal sites of the dopamine d1 receptor regulated striatonigral and the dopamine d2 receptor regulated striatopallidal gaba pathways, respectively. |
1997-01-16 |
2023-08-12 |
rat |
| W Sommer, R Rimondini, W O'Connor, A C Hansson, U Ungerstedt, K Fux. Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 24. 1997-01-16. PMID:8943073. |
intrastriatal infusion of the c-fos antisense oligonucleotide profoundly decreased dialysate gaba levels in the ipsilateral substantia nigra within 60 min but did not influence the dialysate gaba levels in the globus pallidus compared with the sham and control oligonucleotide treated groups. |
1997-01-16 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, I Nylander, M Goiny, J Kehr, U Ungerstedt, L Tereniu. Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963665. |
systemic injection of morphine (1 mg/kg s.c.) induced long-lasting increases in extracellular dynorphin b and gaba levels in the substantia nigra, whereas da, glu and asp levels, measured in the same region, were not significantly affected. |
1996-12-05 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, I Nylander, M Goiny, J Kehr, U Ungerstedt, L Tereniu. Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963665. |
local perfusion of the substantia nigra with morphine (100 microm) through the microdialysis probe also increased nigral dynorphin b and gaba levels. |
1996-12-05 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, I Nylander, M Goiny, J Kehr, U Ungerstedt, L Tereniu. Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963665. |
perfusion of the neostriatum with morphine (100 microm) significantly increased gaba and dynorphin b levels in the ipsilateral substantia nigra, but no effect was observed locally. |
1996-12-05 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, I Nylander, M Goiny, J Kehr, U Ungerstedt, L Tereniu. Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963665. |
naloxone blocked the effect of systemic morphine administration on nigral dynorphin b and gaba release, already at a dose of 0.2 mg/kg s.c. naloxone alone, given either systemically (0.2-4 mg/kg s.c.) or intracerebrally (1-100 microm), did not affect dynorphin b or amino acid levels, either in neostriatum or in substantia nigra. |
1996-12-05 |
2023-08-12 |
rat |
| Z B You, M Herrera-Marschitz, I Nylander, M Goiny, J Kehr, U Ungerstedt, L Tereniu. Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats. Brain research. vol 710. issue 1-2. 1996-12-05. PMID:8963665. |
the present results indicate that systemic morphine administration stimulates the release of dynorphin b in the substantia nigra, probably by activating the mu-subtype of opioid receptor, since the effect of morphine on nigral dynorphin b and gaba was antagonized by a low dose of naloxone. |
1996-12-05 |
2023-08-12 |
rat |
| G Battaglioli, D L Marti. Glutamine stimulates gamma-aminobutyric acid synthesis in synaptosomes but other putative astrocyte-to-neuron shuttle substrates do not. Neuroscience letters. vol 209. issue 2. 1996-12-04. PMID:8761999. |
to test the effect of putative astrocytic shuttle metabolites on gaba synthesis, we used synaptosomes prepared from substantia nigra, an area rich in gabaergic terminals. |
1996-12-04 |
2023-08-12 |
Not clear |
| H Hamano, J Nabekura, M Nishikawa, T Ogaw. Docosahexaenoic acid reduces GABA response in substantia nigra neuron of rat. Journal of neurophysiology. vol 75. issue 3. 1996-12-03. PMID:8867135. |
docosahexaenoic acid reduces gaba response in substantia nigra neuron of rat. |
1996-12-03 |
2023-08-12 |
rat |
| H Hamano, J Nabekura, M Nishikawa, T Ogaw. Docosahexaenoic acid reduces GABA response in substantia nigra neuron of rat. Journal of neurophysiology. vol 75. issue 3. 1996-12-03. PMID:8867135. |
the effects of docosahexaenoic acid (dha) on gamma-aminobutyric acid (gaba) response (igaba) were investigated on the neuron acutely dissociated from rat substantia nigra (sn), with the use of patch recordings in a whole cell mode. |
1996-12-03 |
2023-08-12 |
rat |