| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aimilia Lydia Kalafateli, Tugce Munise Satir, Daniel Vallöf, Henrik Zetterberg, Elisabet Jerlha. An amylin and calcitonin receptor agonist modulates alcohol behaviors by acting on reward-related areas in the brain. Progress in neurobiology. vol 200. 2021-09-23. PMID:33278524. |
alcohol causes stimulatory behavioral responses by activating reward-processing brain areas including the laterodorsal (ldtg) and ventral tegmental areas (vta) and the nucleus accumbens (nac). |
2021-09-23 |
2023-08-13 |
mouse |
| William C Griffin, Harold L Haun, Vorani S Ramachandra, Lori A Knackstedt, Patrick J Mulholland, Howard C Becke. Effects of ceftriaxone on ethanol drinking and GLT-1 expression in ethanol dependence and relapse drinking. Alcohol (Fayetteville, N.Y.). vol 92. 2021-09-23. PMID:33465464. |
previous reports from our laboratory show that cie increases extracellular glutamate in the nucleus accumbens (nac) and that manipulating accumbal glutamate concentrations will alter ethanol drinking, indicating that glutamate homeostasis plays a crucial role in ethanol drinking in this model. |
2021-09-23 |
2023-08-13 |
mouse |
| Qing Shang, Min Liang, Jing Xiao, Baoyao Gao, Hongyan Qian, Jing Wang, Gang Chen, Jie Fang, Tao Li, Xinshe Li. LB100 attenuates methamphetamine-induced behavioral sensitization by inhibiting the Raf1-ERK 1/2 cascade in the caudate putamen. Neuroreport. vol 32. issue 12. 2021-09-20. PMID:34102646. |
in addition, western blot was used to examine the levels of p-raf1 (ser 259) and p-erk 1/2 (thr 202/tyr 204) in the cpu, hippocampus (hip) and nucleus accumbens (nac). |
2021-09-20 |
2023-08-13 |
mouse |
| Jessica J Walsh, Pierre Llorach, Daniel F Cardozo Pinto, Wendy Wenderski, Daniel J Christoffel, Juliana S Salgado, Boris D Heifets, Gerald R Crabtree, Robert C Malenk. Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 11. 2021-09-16. PMID:34239048. |
we recently demonstrated that enhanced serotonin (5-ht) activity in the nucleus accumbens (nac), via optogenetic activation of 5-htergic inputs or direct infusion of a specific 5-ht1b receptor agonist, reverses social deficits in a genetic mouse model for asd based on 16p11.2 copy number variation. |
2021-09-16 |
2023-08-13 |
mouse |
| James Lederman, Sylvie Lardeux, Saleem M Nicol. Vigor Encoding in the Ventral Pallidum. eNeuro. vol 8. issue 4. 2021-09-16. PMID:34326066. |
the ventral pallidum (vp) is the major downstream nucleus of the nucleus accumbens (nac). |
2021-09-16 |
2023-08-13 |
rat |
| Kayla G Townsley, Marissa B Borrego, Angela R Ozbur. Effects of chemogenetic manipulation of the nucleus accumbens core in male C57BL/6J mice. Alcohol (Fayetteville, N.Y.). vol 91. 2021-09-15. PMID:33160072. |
our previous experiments in c57bl/6j female mice found that increasing activity in the nucleus accumbens (nac) core using excitatory designer receptors exclusively activated by designer drugs (dreadds) reduced binge-like drinking. |
2021-09-15 |
2023-08-13 |
mouse |
| Mary B Spodnick, Raymond T Amirault, Trevor T Towner, Elena I Varlinskaya, Linda P Spear, Anushree N Karkhani. Adolescent Intermittent Ethanol Exposure Effects on Kappa Opioid Receptor Mediated Dopamine Transmission: Sex and Age of Exposure Matter. Brain sciences. vol 10. issue 8. 2021-09-14. PMID:32717830. |
the dopamine and kappa opioid receptor (kor) systems in the nucleus accumbens (nac) are implicated in affective disorders, including aud, with studies showing augmented kor function and reduced dopamine transmission in ethanol-dependent adult animals. |
2021-09-14 |
2023-08-13 |
rat |
| Saeedeh Nasrollahi, Sara Karimi, Gholamali Hamidi, Monireh Naderitehrani, Alireza Abe. Blockade of the orexin 1 receptors in the nucleus accumbens' shell reversed the reduction effect of olanzapine on motivation for positive reinforcers. Neuroscience letters. vol 762. 2021-09-14. PMID:34311049. |
the nucleus accumbens (nac) is a region of the neural system that serves effort-related high reward choices andthe orexin 1 receptor (ox1r) is distributed extensively throughout the nucleus accumbens shell (acbs). |
2021-09-14 |
2023-08-13 |
rat |
| Amanda K Fakira, Lindsay M Lueptow, Nikita A Trimbake, Lakshmi A Dev. PEN Receptor GPR83 in Anxiety-Like Behaviors: Differential Regulation in Global vs Amygdalar Knockdown. Frontiers in neuroscience. vol 15. 2021-09-14. PMID:34512237. |
local gpr83 knockdown in the central amygdala or nucleus accumbens (nac) showed no significant effect on anxiety-related behaviors. |
2021-09-14 |
2023-08-13 |
mouse |
| Valeska Cid-Jofré, Macarena Gárate-Pérez, Philip J Clark, Viviana Valero-Jara, Rodrigo A España, Ramón Sotomayor-Zárate, Gonzalo Cruz, Georgina M Renar. Chronic modafinil administration to preadolescent rats impairs social play behavior and dopaminergic system. Neuropharmacology. vol 183. 2021-09-13. PMID:33197467. |
the aim of this work was to evaluate the effects of chronic mod treatment during preadolescence on social play behavior, locomotor activity, and da in nucleus accumbens (nac). |
2021-09-13 |
2023-08-13 |
rat |
| Yasaman Razavi, Mina Rashvand, Asrin Sharifi, Amir Haghparast, Fariborz Keyhanfar, Abbas Haghparas. Cannabidiol microinjection into the nucleus accumbens attenuated nociceptive behaviors in an animal model of tonic pain. Neuroscience letters. vol 762. 2021-09-13. PMID:34324957. |
nucleus accumbens (nac) as a major site of action of cannabinoids is one of the main mediators of several analgesic agents especially in the persistent pain condition. |
2021-09-13 |
2023-08-13 |
rat |
| Tzofnat Bareli, Hadas Levi Ahdoot, Hila Ben-Moshe, Royi Barnea, Gal Warhaftig, Rachel Maayan, Paola Roska, Abraham Weizman, Gal Yadi. Chronic opipramol treatment extinguishes cocaine craving through Rac1 in responders: A rat model study. Addiction biology. vol 26. issue 5. 2021-09-10. PMID:33508873. |
all opipramol-treated rats showed a decrease in σ-1r mrna expression levels in the nucleus accumbens (nac) versus controls. |
2021-09-10 |
2023-08-13 |
rat |
| Dan P Covey, Alyssa G Yock. Endocannabinoid Modulation of Nucleus Accumbens Microcircuitry and Terminal Dopamine Release. Frontiers in synaptic neuroscience. vol 13. 2021-09-10. PMID:34497503. |
the nucleus accumbens (nac) is located in the ventromedial portion of the striatum and is vital to valence-based predictions and motivated action. |
2021-09-10 |
2023-08-13 |
Not clear |
| Mi Seon Kim, Yu Fan, Soo Min Lee, Su Chan Chang, Hyung Kyu Kim, Yeonhee Ryu, Scott C Steffensen, Chae Ha Yang, Hee Young Ki. Role of the central amygdala in acupuncture inhibition of methamphetamine-induced behaviors in rats. Addiction biology. vol 26. issue 1. 2021-09-09. PMID:31997525. |
our previous studies have shown that acupuncture attenuates drug-seeking behaviors by modulating gabaergic transmission in the ventral tegmental area and da release in the nucleus accumbens (nac) of the striatum. |
2021-09-09 |
2023-08-13 |
rat |
| Conner W Wallace, Nari S Beatty, Sarah A Hutcherson, Heather A Emmons, Madison C Loudermilt, Steve C Fordah. Replacing a Palatable High-Fat Diet with a Low-Fat Alternative Heightens κ-Opioid Receptor Control over Nucleus Accumbens Dopamine. Nutrients. vol 13. issue 7. 2021-09-08. PMID:34371851. |
diet-induced obesity reduces dopaminergic neurotransmission in the nucleus accumbens (nac), and stressful weight loss interventions could promote cravings for palatable foods high in fat and sugar that stimulate dopamine. |
2021-09-08 |
2023-08-13 |
mouse |
| Chrysostomos Charalambous, Marek Lapka, Tereza Havlickova, Kamila Syslova, Magdalena Sustkova-Fiserov. Alterations in Rat Accumbens Dopamine, Endocannabinoids and GABA Content During WIN55,212-2 Treatment: The Role of Ghrelin. International journal of molecular sciences. vol 22. issue 1. 2021-09-07. PMID:33379212. |
the endocannabinoid/cb1r system as well as the central ghrelin signalling with its growth hormone secretagogoue receptors (ghs-r1a) are importantly involved in food intake and reward/reinforcement processing and show distinct overlaps in distribution within the relevant brain regions including the hypothalamus (food intake), the ventral tegmental area (vta) and the nucleus accumbens (nac) (reward/reinforcement). |
2021-09-07 |
2023-08-13 |
rat |
| Elham Charmchi, Golnaz Faramarzi, Mina Rashvand, Morteza Zendehdel, Abbas Haghparas. Restraint Stress Potentiated Morphine Sensitization: Involvement of Dopamine Receptors within the Nucleus Accumbens. Neurochemical research. vol 46. issue 3. 2021-09-07. PMID:33389471. |
the development of morphine sensitization is associated with enhancements in dopamine overflow in the nucleus accumbens (nac). |
2021-09-07 |
2023-08-13 |
rat |
| Giuseppe Giannotti, Sheng Gong, Nicholas Fayette, Jasper A Heinsbroek, James E Orfila, Paco S Herson, Christopher P Ford, Jamie Peter. Extinction blunts paraventricular thalamic contributions to heroin relapse. Cell reports. vol 36. issue 8. 2021-09-07. PMID:34433067. |
here, we use optogenetics and chemogenetics to investigate the contribution of the paraventricular thalamus (pvt) to nucleus accumbens (nac) pathway in aversion and heroin relapse in two different heroin self-administration models in rats. |
2021-09-07 |
2023-08-13 |
rat |
| Dan Liu, Min Liang, Li Zhu, Ting-Ting Zhou, Yu Wang, Rui Wang, Fei-Fei Wu, Eyleen L K Goh, Teng Che. Potential Ago2/miR-3068-5p Cascades in the Nucleus Accumbens Contribute to Methamphetamine-Induced Locomotor Sensitization of Mice. Frontiers in pharmacology. vol 12. 2021-09-07. PMID:34483916. |
argonaute2 (ago2), a specific splicing protein involved in the generation of mirna, was found to be dysregulated in the nucleus accumbens (nac) of methamphetamine (meth)-sensitized mice in our previous study. |
2021-09-07 |
2023-08-13 |
mouse |
| Joyce T Da Silva, Christina Tricou, Youping Zhang, Amir Tofighbakhsh, David A Seminowicz, Jin Y R. Pain modulatory network is influenced by sex and age in a healthy state and during osteoarthritis progression in rats. Aging cell. vol 20. issue 2. 2021-09-06. PMID:33400367. |
young females exhibited widespread pag fc in the early phase, which includes connections to insula, caudal acc, and nucleus accumbens (nac). |
2021-09-06 |
2023-08-13 |
rat |