| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Conner W Wallace, Steve C Fordah. Obesity and dietary fat influence dopamine neurotransmission: exploring the convergence of metabolic state, physiological stress, and inflammation on dopaminergic control of food intake. Nutrition research reviews. 2021-08-16. PMID:34184629. |
the aim of this review is to explore how metabolic changes induced by diets high in saturated fat (hfd) affect nucleus accumbens (nac) dopamine neurotransmission and food intake, and to explore how stress and inflammation influence this process. |
2021-08-16 |
2023-08-13 |
Not clear |
| Jie Li, Chen Lu, Zilong Gao, Yifan Feng, Huoqing Luo, Tangsheng Lu, Xia Sun, Ji Hu, Yanli Lu. SNRIs achieve faster antidepressant effects than SSRIs by elevating the concentrations of dopamine in the forebrain. Neuropharmacology. vol 177. 2021-08-12. PMID:32710978. |
in our study, a genetically encoded dopamine sensor and in vivo fiber photometry recordings were used to measure the dopamine concentrations in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) after acute intraperitoneal injection of ssris or snris. |
2021-08-12 |
2023-08-13 |
Not clear |
| Shannon L Cole, Ramesh Chandra, Maya Harris, Ishan Patel, Torrance Wang, Hyunjae Kim, Leah Jensen, Scott J Russo, Gustavo Turecki, Amy M Gancarz-Kausch, David M Dietz, Mary Kay Lob. Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34187517. |
recent studies demonstrate that cocaine affects mitochondrial dynamics and morphological characteristics within the nucleus accumbens (nac). |
2021-08-12 |
2023-08-13 |
human |
| Bo Söderpalm, Klara Danielsson, Andrea de Bejczy, Louise Adermark, Mia Ericso. Combined administration of varenicline and bupropion produces additive effects on accumbal dopamine and abolishes the alcohol deprivation effect in rats. Addiction biology. vol 25. issue 5. 2021-08-11. PMID:31293045. |
smoking and aud share heritability and are pharmacologically associated, since drug-induced dopamine (da) output in nucleus accumbens (nac) involves nicotinic acetylcholine receptors (nachrs) in both cases. |
2021-08-11 |
2023-08-13 |
rat |
| Cristina Cadoni, Marta De Felice, Silvia Corongiu, Christian Dessì, Elena Espa, Miriam Melis, Sandro Fen. Role of genetic background in the effects of adolescent nicotine exposure on mesolimbic dopamine transmission. Addiction biology. vol 25. issue 5. 2021-08-11. PMID:31342609. |
a potentiation of dopamine response to nicotine was observed in nucleus accumbens (nac) core of both strains and age groups, whereas dopamine response in nac shell was enhanced exclusively in lewis rats exposed to nicotine during adolescence. |
2021-08-11 |
2023-08-13 |
rat |
| Wei Guo, Hailei Long, Qian Bu, Yinglan Zhao, Hongbo Wang, Jingwei Tian, Xiaobo Ce. Role of BRD4 phosphorylation in the nucleus accumbens in relapse to cocaine-seeking behavior in mice. Addiction biology. vol 25. issue 5. 2021-08-11. PMID:31364211. |
in this study, we found that brd4 phosphorylation in the nucleus accumbens (nac) was closely related to the maintenance of cocaine reinforcement and relapse in different cocaine exposure paradigms. |
2021-08-11 |
2023-08-13 |
mouse |
| Grace J Lee, Shin Ae Kim, Yea Jin Kim, Seog Bae O. Naloxone-induced analgesia mediated by central kappa opioid system in chronic inflammatory pain. Brain research. vol 1762. 2021-08-11. PMID:33766518. |
immunohistochemistry analysis in the cfa model revealed both a significant decrease in mor expression and an increase in prodynorphin density in the central nucleus of theamygdala (cea) and nucleus accumbens (nac) but not in other brain areas. |
2021-08-11 |
2023-08-13 |
Not clear |
| Jennaya Christensen, Glenn R Yamakawa, Sabrina Salberg, Melinda Wang, Bryan Kolb, Richelle Mychasiu. Caffeine consumption during development alters spine density and recovery from repetitive mild traumatic brain injury in young adult rats. Synapse (New York, N.Y.). vol 74. issue 4. 2021-08-10. PMID:31705690. |
both caffeine and rmtbi increased spine density in the cg3 (medial prefrontal cortex [mpfc]), aid (orbitofrontal cortex [ofc]), and nucleus accumbens (nac), which is proposed to reflect an impairment in the normal pruning processes. |
2021-08-10 |
2023-08-13 |
rat |
| H Z Rosa, R C S Barcelos, H J Segat, Kr Roversi, V T Dias, L H Milanesi, M E Burge. Physical exercise modifies behavioral and molecular parameters related to opioid addiction regardless of training time. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 32. 2021-08-10. PMID:31899030. |
on the last exercising week, one-half of the animals from sed and all animals from s-, m- and l-exe were concomitantly exposed to morphine-conditioned place preference (cpp) paradigm and y-maze task for behavioral assessments followed by molecular assays in both nucleus accumbens (nac) and hippocampus. |
2021-08-10 |
2023-08-13 |
rat |
| Hui Shen, Kai Chen, Rosa Anna M Marino, Ross A McDevitt, Zheng-Xiong X. Deletion of VGLUT2 in midbrain dopamine neurons attenuates dopamine and glutamate responses to methamphetamine in mice. Pharmacology, biochemistry, and behavior. vol 202. 2021-08-10. PMID:33444596. |
to test this hypothesis, we used cre-loxp techniques to selectively delete vglut2 from midbrain da neurons, and then examined nucleus accumbens (nac) da and glutamate responses to meth using in vivo brain microdialysis between da-vglut2-ko mice and their vglut2-het littermates. |
2021-08-10 |
2023-08-13 |
mouse |
| Hassan Jorjani, Marzieh Joneidi, Abbas Ali Vafaei, Ali Rashidy-Pour, Hamidreza Sameni, Ahmad Reza Bandegi, Behpour Yousefi, Hossein Miladi-Gorj. Microinjection of the BDNF receptor antagonist ANA-12 into the nucleus accumbens and medial-prefrontal cortex attenuates morphine-induced reward memory, and alterations of BDNF levels and apoptotic cells in rats. Pharmacology, biochemistry, and behavior. vol 201. 2021-08-10. PMID:33444602. |
this study was designed to examine the effects of intra- nucleus accumbens (nac) of bdnf receptor antagonist ana-12 on the acquisition and expression and intra- medial-prefrontal cortex (mpfc) of ana-12 on the extinction and reinstatement of morphine-induced conditioned place preference (cpp) and also bdnf levels and apoptotic neurons in the nac and mpfc of rats. |
2021-08-10 |
2023-08-13 |
rat |
| b' Thibault P Bittar, Mari Carmen Pelaez, Jose Cesar Hernandez Silva, Francis Quessy, Andr\\xc3\\xa9e-Anne Lavigne, Daphn\\xc3\\xa9e Morency, L\\xc3\\xa9a-Jeanne Blanchette, Eric Arsenault, Yoan Cherasse, Jos\\xc3\\xa9e Seigneur, Igor Timofeev, Chantelle F Sephton, Christophe D Proulx, Benoit Labont\\xc3\\xa. Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways. Biological psychiatry. vol 90. issue 3. 2021-08-10. PMID:33867113.' |
the medial prefrontal cortex (mpfc) is part of a complex circuit controlling stress responses by sending projections to different limbic structures including the nucleus accumbens (nac) and ventral tegmental area (vta). |
2021-08-10 |
2023-08-13 |
Not clear |
| Yinghao Yu, Alan Bohan He, Michelle Liou, Chenyin Ou, Anna Kozłowska, Pingwen Chen, Andrew Chihwei Huan. The Paradoxical Effect Hypothesis of Abused Drugs in a Rat Model of Chronic Morphine Administration. Journal of clinical medicine. vol 10. issue 15. 2021-08-09. PMID:34361981. |
for assessments of c-fos and p-erk expression, the cingulate cortex 1 (cg1), prelimbic cortex (prl), infralimbic cortex (il), basolateral amygdala (bla), nucleus accumbens (nac), and dentate gyrus (dg) were involved in the morphine-induced cta, and resulted from the aversive effect of morphine on conditioning and reinstatement. |
2021-08-09 |
2023-08-13 |
rat |
| Steven J Nieto, Colin N Haile, Cana B Quave, Mark J Harding, David A Nielsen, Richard A Meisch, Therese A Koste. Paternal alcohol exposure reduces acquisition of operant alcohol self-administration and affects Bdnf DNA methylation in male and female offspring. Addiction biology. 2021-08-07. PMID:34363290. |
dna methylation levels of the brain derived neurotrophic factor (bdnf) gene were measured in sperm, nucleus accumbens (nac) and medial prefrontal cortex (mpfc) in sires and in offspring. |
2021-08-07 |
2023-08-13 |
mouse |
| Rajas P Kale, Thanh Thanh L Nguyen, J Blair Price, Nathanael J Yates, Ken Walder, Michael Berk, Roy V Sillitoe, Abbas Z Kouzani, Susannah J Ty. Mood Regulatory Actions of Active and Sham Nucleus Accumbens Deep Brain Stimulation in Antidepressant Resistant Rats. Frontiers in human neuroscience. vol 15. 2021-08-06. PMID:34349629. |
we investigated the antidepressant-like effects of chronic nucleus accumbens (nac) dbs and its association with change in glycogen synthase kinase 3 (gsk3) and mammalian target of rapamycin (mtor) expression in the infralimbic cortex (il), and the dorsal (dhip) and ventral (vhip) subregions of the hippocampus of antidepressant resistant rats. |
2021-08-06 |
2023-08-13 |
rat |
| Travis M Moschak, Regina M Carell. A sex-dependent role for the prelimbic cortex in impulsive action both before and following early cocaine abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 9. 2021-08-04. PMID:33972695. |
neural activity in the prelimbic cortex (prl) and nucleus accumbens (nac) core was assessed at each time point. |
2021-08-04 |
2023-08-13 |
rat |
| Bérangère Detraux, Antonietta Vilella, Aurélie De Groote, Serge N Schiffmann, Michele Zoli, Alban de Kerchove d'Exaerd. Dorsal and ventral striatal neuronal subpopulations differentially disrupt male mouse copulatory behavior. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 49. 2021-08-03. PMID:33780705. |
in order to clarify their contribution to male sexual behavior, we specifically ablated the major striatal neuronal subpopulations, direct and indirect medium spiny neurons (dmsns and imsns) in dms or dls, and dmsns, imsns and cholinergic interneurons in nucleus accumbens (nac), the main results of this study can be summarized as follows: in dms, dmsn ablation causes a reduction in the percent of mice that mount a receptive female, and a complex alteration in the parameters of the copulatory performance, that is largely opposite to the alterations induced by imsn ablation. |
2021-08-03 |
2023-08-13 |
mouse |
| Masaki Tanaka, Shunji Yamada, Yoshihisa Watanab. The Role of Neuropeptide Y in the Nucleus Accumbens. International journal of molecular sciences. vol 22. issue 14. 2021-08-03. PMID:34298907. |
in particular, the nucleus accumbens (nac) has one of the highest npy concentrations in the brain. |
2021-08-03 |
2023-08-13 |
Not clear |
| Yujie Wu, Donghang Zhang, Jin Liu, Yaoxin Yang, Mengchan Ou, Bin Liu, Cheng Zho. Sodium Leak Channel in the Nucleus Accumbens Modulates Ethanol-Induced Acute Stimulant Responses and Locomotor Sensitization in Mice: A Brief Research Report. Frontiers in neuroscience. vol 15. 2021-08-03. PMID:34335164. |
accordingly, the expression levels of nalcn mrna and protein in the nucleus accumbens (nac) were markedly increased in the sensitization mice compared to the control mice. |
2021-08-03 |
2023-08-13 |
mouse |
| Angela M Lee, Mohammad Shahid Mansuri, Rashaun S Wilson, TuKiet T Lam, Angus C Nairn, Marina R Picciott. Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. Frontiers in molecular neuroscience. vol 14. 2021-08-03. PMID:34335180. |
in this study we evaluated the proteome in the ventral tegmental area (vta) and nucleus accumbens (nac) shell in male and female mice. |
2021-08-03 |
2023-08-13 |
mouse |