| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karen K Szumlinski, Daria L Thompson, Rachel M Renton, Alexis W Ary, Kevin D Lomina. Enduring dysregulation of nucleus accumbens catecholamine and glutamate transmission by developmental exposure to phenylpropanolamine. Brain research. vol 1748. 2021-10-25. PMID:32896521. |
previously, we reported that juvenile ppa exposure alters the developmental trajectory of catecholamine and amino acid neurotransmitter systems in the nucleus accumbens (nac), impacting the motivational valence of cocaine in later life. |
2021-10-25 |
2023-08-13 |
mouse |
| Molly Estill, Efrain Ribeiro, Nancy J Francoeur, Melissa L Smith, Robert Sebra, Szu-Ying Yeh, Ashley M Cunningham, Eric J Nestler, Li She. Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. Scientific reports. vol 11. issue 1. 2021-10-25. PMID:33762610. |
to better understand the full-length transcriptome of the nucleus accumbens (nac)-a key brain reward region-in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the iso-seq method to detect 42,114 unique transcripts from mouse nac polyadenylated rna. |
2021-10-25 |
2023-08-13 |
mouse |
| Steven R Laviolett. Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders. Neuropharmacology. vol 184. 2021-10-22. PMID:33245960. |
nicotine can potently regulate the transmission of various neurochemicals, including dopamine (da), γ-amino-butyric acid (gaba) and glutamate, within various mesocorticolimbic structures, such as the ventral tegmental area (vta), nucleus accumbens (nac) and prefrontal cortex (pfc), all of which show pathologies in these disorders. |
2021-10-22 |
2023-08-13 |
Not clear |
| Sanjeev K Bhardwaj, Qiming Cui, Luc Moquin, Alain Gratton, Bruno Giros, Lalit K Srivastav. Mice with dopaminergic neuron-specific deletion of DTNBP-1 gene show blunted nucleus accumbens dopamine release and associated behaviors. Neuropharmacology. vol 184. 2021-10-22. PMID:33340529. |
in- vivo microdialysis in the nucleus accumbens (nac) showed a decrease in d-amph-induced extracellular da release in the cko mice. |
2021-10-22 |
2023-08-13 |
mouse |
| Jonathan J Chow, Rebecca S Hofford, Joshua S Beckman. Neuronal activity associated with cocaine preference: Effects of differential cocaine intake. Neuropharmacology. vol 184. 2021-10-22. PMID:33340530. |
herein, a choice procedure that controls for cocaine intake was utilized to explore if neuronal activity, measured as cfos expression in the orbitofrontal cortex (ofc) and nucleus accumbens (nac), was reflective of preference. |
2021-10-22 |
2023-08-13 |
human |
| Martyna Bayassi-Jakowicka, Grazyna Lietzau, Ewelina Czuba, Aleksandra Steliga, Monika Waśkow, Przemysław Kowiańsk. Neuroplasticity and Multilevel System of Connections Determine the Integrative Role of Nucleus Accumbens in the Brain Reward System. International journal of molecular sciences. vol 22. issue 18. 2021-10-22. PMID:34575969. |
a growing body of evidence suggests that nucleus accumbens (nac) plays a significant role not only in the physiological processes associated with reward and satisfaction but also in many diseases of the central nervous system. |
2021-10-22 |
2023-08-13 |
Not clear |
| Martin O Job, Michael J Kuha. Intraperitoneal Administration of CART 55-102 Inhibits Psychostimulant-Induced Locomotion. Journal of drug and alcohol research. vol 1. 2021-10-21. PMID:23705073. |
cart peptide in the nucleus accumbens (nac) has been implicated in the regulation of cocaine-dopamine-mediated locomotion and self-administration, and amphetamine-mediated locomotion and behavior. |
2021-10-21 |
2023-08-12 |
rat |
| Steven Kushner, David Han, Marlene Oscar-Berman, B William Downs, Margaret A Madigan, John Giordano, Thomas Beley, Scott Jones, Debmayla Barh, Thomas Simpatico, Kristina Dushaj, Raquel Lohmann, Eric R Braverman, Stephen Schoenthaler, David Ellison, Kenneth Blu. Declinol, a Complex Containing Kudzu, Bitter Herbs (Gentian, Tangerine Peel) and Bupleurum, Significantly Reduced Alcohol Use Disorders Identification Test (AUDIT) Scores in Moderate to Heavy Drinkers: A Pilot Study. Journal of addiction research & therapy. vol 4. issue 3. 2021-10-21. PMID:24273684. |
moreover, it has been suggested that selective aldh 2 inhibitors reduce craving for alcohol by increasing dopamine in the nucleus accumbens (nac). |
2021-10-21 |
2023-08-12 |
human |
| María E Vélez-Hernández, Rafael Vázquez-Torres, Maria C Velasquez-Martinez, Lincoln Jiménez, Frankie Báez, Todd C Sacktor, Carlos A Jiménez-River. Inhibition of Protein kinase Mzeta (PKMζ) in the mesolimbic system alters cocaine sensitization in rats. Journal of drug and alcohol research. vol 2. 2021-10-21. PMID:24729912. |
on the other hand, zip microinfusions into the nucleus accumbens (nac) core after a seven days withdrawal period disrupt the expression of locomotor sensitization. |
2021-10-21 |
2023-08-13 |
rat |
| Olga Skiteva, Ning Yao, Karima Chergu. Ketamine induces opposite changes in AMPA receptor calcium permeability in the ventral tegmental area and nucleus accumbens. Translational psychiatry. vol 11. issue 1. 2021-10-21. PMID:34650029. |
the mechanisms might involve the induction of metaplasticity in brain regions associated with reward-related behaviors, mood, and hedonic drive, particularly the ventral tegmental area (vta) and the nucleus accumbens (nac). |
2021-10-21 |
2023-08-13 |
mouse |
| Alyse N Maksimoski, Brandon J Polzin, Sharon A Stevenson, Changjiu Zhao, Lauren V Riter. μ-Opioid Receptor Stimulation in the Nucleus Accumbens Increases Vocal-Social Interactions in Flocking European Starlings, eNeuro. vol 8. issue 5. 2021-10-20. PMID:34475266. |
the μ-opioid receptors (mors) in the nucleus accumbens (nac) are well known for their role in both reward and the reduction of negative affective states, suggesting that mor stimulation in nac may play a critical role in flock cohesion. |
2021-10-20 |
2023-08-13 |
Not clear |
| Conor H Murray, Andrew D Gaulden, Alex B Kawa, Mike Milovanovic, Aaron J Caccamise, Jonathan R Funke, Sachin Patel, Marina E Wol. CaMKII Modulates Diacylglycerol Lipase-α Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving. eNeuro. vol 8. issue 5. 2021-10-20. PMID:34544759. |
incubation of cocaine craving involves the strengthening of excitatory synapses onto nucleus accumbens (nac) medium spiny neurons via postsynaptic accumulation of high-conductance ca |
2021-10-20 |
2023-08-13 |
rat |
| Catherine S Thomas, Aida Mohammadkhani, Madiha Rana, Min Qiao, Corey Baimel, Stephanie L Borglan. Optogenetic stimulation of lateral hypothalamic orexin/dynorphin inputs in the ventral tegmental area potentiates mesolimbic dopamine neurotransmission and promotes reward-seeking behaviours. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-10-19. PMID:34663867. |
we found that optical stimulation of lh orexin/dynorphin inputs in the vta potentiates mesolimbic dopamine neurotransmission in the nucleus accumbens (nac) core, produces real time and conditioned place preference, and increases the food cue-directed orientation in a pavlovian conditioning procedure. |
2021-10-19 |
2023-08-13 |
Not clear |
| Sara E Keefer, Utsav Gyawali, Donna J Cal. Choose your path: Divergent basolateral amygdala efferents differentially mediate incentive motivation, flexibility and decision-making. Behavioural brain research. vol 409. 2021-10-18. PMID:33887310. |
specifically, we compare and contrast divergent projections from the bla to the orbitofrontal (ofc) and to the nucleus accumbens (nac) and examine the roles of these pathways in associative learning, value-guided decision-making, choice behaviors, as well as cue and context-driven drug seeking. |
2021-10-18 |
2023-08-13 |
Not clear |
| Hailei Yu, Bing Xie, Jingjing Zhang, Yixiao Luo, Ewa Galaj, Xiuning Zhang, Qianchao Shen, Yi Liu, Bin Cong, Di Wen, Chunling M. The role of circTmeff-1 in incubation of context-induced morphine craving. Pharmacological research. vol 170. 2021-10-18. PMID:34116208. |
in the present study, we trained mice to morphine conditioned place preference (cpp) and collected the nucleus accumbens (nac) sections on abstinence day 1 (ad1) and day 14 (ad14) for rna-sequencing. |
2021-10-18 |
2023-08-13 |
mouse |
| Kevin M Manz, Benjamin C Coleman, Alexis N Jameson, Dipanwita G Ghose, Sachin Patel, Brad A Gruete. Cocaine restricts nucleus accumbens feedforward drive through a monoamine-independent mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-10-16. PMID:34545194. |
parvalbumin-expressing fast-spiking interneurons (pv-ins) within feedforward microcircuits in the nucleus accumbens (nac) coordinate goal-directed motivational behavior. |
2021-10-16 |
2023-08-13 |
mouse |
| Omron Hassan, Sheshanna Phan, Nicole Wiecks, Christian Joaquin, Vladimir Bondarenk. Outcomes of deep brain stimulation surgery for substance use disorder: a systematic review. Neurosurgical review. vol 44. issue 4. 2021-10-15. PMID:33037538. |
all studies targeted the nucleus accumbens (nac) and remission rates at 6 months, 1 year, 2 years, and more than 6 years were 61% (20/33), 53% (17/32), 43% (14/30), and 50% (3/6), respectively. |
2021-10-15 |
2023-08-13 |
Not clear |
| Yasmin Olsson, Helga Höifödt Lidö, Klara Danielsson, Mia Ericson, Bo Söderpal. Effects of systemic glycine on accumbal glycine and dopamine levels and ethanol intake in male Wistar rats. Journal of neural transmission (Vienna, Austria : 1996). vol 128. issue 1. 2021-10-15. PMID:33351169. |
basal and ethanol-induced accumbal dopamine release in the rat involve glycine receptors (glyr) in the nucleus accumbens (nac). |
2021-10-15 |
2023-08-13 |
rat |
| Fernando Lopez-Sosa, Blanca Reneses, Florencia Sanmartino, Ana Galarza-Vallejo, Julia Garcia-Albea, Alvaro J Cruz-Gomez, Mar Yebra, Antonio Oliviero, Juan A Barcia, Bryan A Strange, Javier J Gonzalez-Ros. Nucleus Accumbens Stimulation Modulates Inhibitory Control by Right Prefrontal Cortex Activation in Obsessive-Compulsive Disorder. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 5. 2021-10-15. PMID:33406245. |
here, 9 refractory ocd patients treated with deep brain stimulation (dbs) were evaluated to address the dynamic modulations of large-scale cortical network activity involved in inhibitory control after nucleus accumbens (nac) stimulation and their relationship with cortical thickness. |
2021-10-15 |
2023-08-13 |
Not clear |
| L M Molina-Martínez, J Juáre. Deficit of β-endorphin neurons in the hypothalamus and high expression of MOR in mesolimbic structures are related to high alcohol consumption in outbred rats. Alcohol (Fayetteville, N.Y.). vol 95. 2021-10-15. PMID:34022405. |
we analyzed the number of β-endorphin-positive neurons in the arcuate nucleus (arn) and the expression of μ-opioid receptors (mor) in regions of the reward system, such as the nucleus accumbens (nac), amygdala (amy), and ventral tegmental area (vta) in outbred rats with low (lc) or high (hc) voluntary alcohol consumption. |
2021-10-15 |
2023-08-13 |
rat |