| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haleh Amirteymori, Saeideh Karimi-Haghighi, Mahboobeh Mirmohammadi, Maryam Majidinezhad, Elahe Khosrowabadi, Abbas Haghparas. Hypocretin/orexin system in the nucleus accumbens as a promising player in the extinction and reinstatement of methamphetamine-induced CPP. Progress in neuro-psychopharmacology & biological psychiatry. 2022-08-21. PMID:35988849. |
the nucleus accumbens (nac) is located in the basal forebrain, responsible for regulating several behaviors, specifically reward-related effect of psychostimulants. |
2022-08-21 |
2023-08-14 |
rat |
| D Iezzi, L Curti, G Ranieri, E Gerace, A Costa, A Ilari, A La Rocca, C Luceri, M D'Ambrosio, L Silvestri, M Scardigli, G Mannaioni, A Mas. Acute rapamycin rescues the hyperexcitable phenotype of accumbal medium spiny neurons in the valproic acid rat model of autism spectrum disorder. Pharmacological research. 2022-08-20. PMID:35987482. |
we previously demonstrated that prenatal exposure to valproic acid (vpa), an environmental model of autism spectrum disorder (asd), leads to a hyperexcitable phenotype associated with downregulation of inward-rectifying potassium currents in nucleus accumbens (nac) medium spiny neurons (msns) of adolescent rats. |
2022-08-20 |
2023-08-14 |
rat |
| Ana Verónica Domingues, Bárbara Coimbra, Raquel Correia, Catarina Deseyve, Natacha Vieitas-Gaspar, Stan B Floresco, Nuno Sousa, Carina Soares-Cunha, Ana João Rodrigue. Prenatal dexamethasone exposure alters effort decision making and triggers nucleus accumbens and anterior cingulate cortex functional changes in male rats. Translational psychiatry. vol 12. issue 1. 2022-08-19. PMID:35986000. |
different brain regions coordinate this complex decision, including the nucleus accumbens (nac), anterior cingulate cortex (acc), and ventral tegmental area (vta). |
2022-08-19 |
2023-08-14 |
rat |
| Benfu Wang, Xiaowei Yang, Wenhua Zhou, Huaqiang Zhu, Qingquan Lian, Jianping Yan. Involvement of the ERK signaling pathways in the NAc in propofol-seeking behavior induced by cues in rats. Pharmacology, biochemistry, and behavior. 2022-08-15. PMID:35970339. |
in the previous study, we demonstrated that the erk signaling pathways in the nucleus accumbens (nac) were involved in propofol reward. |
2022-08-15 |
2023-08-14 |
rat |
| Yang Chen, Libo Zhang, Zengbo Ding, Xianwen Wu, Guibin Wang, Jie Sh. Effects of 3-methylmethcathinone on conditioned place preference and anxiety-like behavior: Comparison with methamphetamine. Frontiers in molecular neuroscience. vol 15. 2022-08-08. PMID:35935336. |
then, we performed a whole-brain c-fos mapping to identify the specific brain regions in response to 3-mmc exposure and explored the changes of synaptic transmission in nucleus accumbens (nac) using patch-clamp recording after chronic 3-mmc and meth exposure. |
2022-08-08 |
2023-08-14 |
rat |
| Nan Dong, Jie Zhu, Rui Wang, Shuai Wang, Yanjiong Chen, Changhe Wang, Eyleen L K Goh, Teng Che. Maternal Methamphetamine Exposure Influences Behavioral Sensitization and Nucleus Accumbens DNA Methylation in Subsequent Generation. Frontiers in pharmacology. vol 13. 2022-08-05. PMID:35928279. |
we then utilized whole genome-bisulfite sequencing (wgbs) to investigate the methylation signature of nucleus accumbens (nac) in male meth-sensitized mice. |
2022-08-05 |
2023-08-14 |
mouse |
| Katherine J Robinson, Nicholas A Everett, Sarah J Baracz, Jennifer L Cornis. The effect of self-administered methamphetamine on GABAergic interneuron populations and functional connectivity of the nucleus accumbens and prefrontal cortex. Psychopharmacology. 2022-08-03. PMID:35920922. |
here we investigate meth-induced changes to neuronal nitric oxide synthase (nnos), parvalbumin and calretinin-expressing gabaergic interneuron populations within the nucleus accumbens (nac), prefrontal cortex (pfc) and orbitofrontal cortex (ofc). |
2022-08-03 |
2023-08-14 |
Not clear |
| Nicholas K Smith, Veronika Kondev, Thomas R Hunt, Brad A Gruete. Neuropeptide Y modulates excitatory synaptic transmission and promotes social behavior in the mouse nucleus accumbens. Neuropharmacology. 2022-08-02. PMID:35917875. |
these receptors are present in brain regions that control social behavior, including the nucleus accumbens (nac). |
2022-08-02 |
2023-08-14 |
mouse |
| David Lindenbach, Giada Vacca, Soyon Ahn, Jeremy K Seamans, Anthony G Phillip. Optogenetic modulation of glutamatergic afferents from the ventral subiculum to the nucleus accumbens: Effects on dopamine function, response vigor and locomotor activity. Behavioural brain research. 2022-08-01. PMID:35914634. |
dopamine (da) signalling in the nucleus accumbens (nac) motivates behavior in part by adjusting the exerted effort according to the anticipated value of the outcome. |
2022-08-01 |
2023-08-14 |
Not clear |
| J Daniel Obray, Christina A Small, Emily K Baldwin, Eun Young Jang, Jin Gyeom Lee, Chae Ha Yang, Jordan T Yorgason, Scott C Steffense. Dopamine D2-Subtype Receptors Outside the Blood-Brain Barrier Mediate Enhancement of Mesolimbic Dopamine Release and Conditioned Place Preference by Intravenous Dopamine. Frontiers in cellular neuroscience. vol 16. 2022-07-29. PMID:35903367. |
this study was designed to investigate whether da subtype-2 receptors are involved in the enhancement of nucleus accumbens (nac) da levels elicited by intravenous da administration. |
2022-07-29 |
2023-08-14 |
Not clear |
| Yuka Kusui, Naotaka Izuo, Kyosuke Uno, Bin Ge, Shin-Ichi Muramatsu, Atsumi Nitt. Knockdown of Piccolo in the Nucleus Accumbens Suppresses Methamphetamine-Induced Hyperlocomotion and Conditioned Place Preference in Mice. Neurochemical research. 2022-07-29. PMID:35906352. |
the presynaptic protein "piccolo", encoded by pclo, was identified as a meth-responsive protein with enhanced expression in the nucleus accumbens (nac) in mice. |
2022-07-29 |
2023-08-14 |
mouse |
| Brianna E George, Monica H Dawes, Emily G Peck, Sara R Jone. Altered Accumbal Dopamine Terminal Dynamics Following Chronic Heroin Self-Administration. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897682. |
withdrawal from chronic heroin exposure is likely to drive a state of low dopamine in the nucleus accumbens (nac), as previously observed during withdrawal from other drug classes. |
2022-07-28 |
2023-08-14 |
rat |
| H A Emmons, C W Wallace, S C Fordah. Interleukin-6 and tumor necrosis factor-α attenuate dopamine release in mice fed a high-fat diet, but not medium or low-fat diets. Nutritional neuroscience. 2022-07-28. PMID:35900193. |
the purpose of this study was to examine how dopamine terminals are affected by pro-inflammatory cytokines, and to determine if dietary fat consumption potentiates cytokine effects on dopamine release and reuptake rate in the nucleus accumbens (nac). |
2022-07-28 |
2023-08-14 |
mouse |
| Zhuo Liu, Jianjun Zhang, Linqing Miao, Qingyao Kong, Xiaodong Liu, Longchuan Y. A Novel CaMKII Inhibitory Peptide Blocks Relapse to Morphine Seeking by Influencing Synaptic Plasticity in the Nucleus Accumbens Shell. Brain sciences. vol 12. issue 8. 2022-07-27. PMID:35892425. |
in this research, by using an animal model of morphine self-administration in rats and a whole-cell patch-clamp in brain slices, we found changes in synaptic plasticity in the nucleus accumbens (nac) shell were involved in the relapse to morphine-seeking behavior. |
2022-07-27 |
2023-08-14 |
rat |
| Tomer Mizrachi Zer-Aviv, Larglinda Islami, Peter J Hamilton, Eric M Parise, Eric J Nestler, Brenda Sbarski, Irit Akira. Enhancing Endocannabinoid Signaling via β-Catenin in the Nucleus Accumbens Attenuates PTSD- and Depression-like Behavior of Male Rats. Biomedicines. vol 10. issue 8. 2022-07-27. PMID:35892688. |
we examined whether the stress-preventing effects of the faah inhibitor urb597 on behavior are mediated via β-catenin in the nucleus accumbens (nac). |
2022-07-27 |
2023-08-14 |
rat |
| Qing Shang, Jing Wang, Zhijia Xi, Baoyao Gao, Hongyan Qian, Ran An, Gaojie Shao, Hua Liu, Tao Li, Xinshe Li. Mechanisms underlying microRNA-222-3p modulation of methamphetamine-induced conditioned place preference in the nucleus accumbens in mice. Psychopharmacology. 2022-07-26. PMID:35881147. |
microrna (mirna) control of post-transcription gene expression in the nucleus accumbens (nac) has been implicated in methamphetamine (meth) dependence. |
2022-07-26 |
2023-08-14 |
mouse |
| L Stan Leung, Jingyi M. Medial Septum Modulates Consciousness and Psychosis-Related Behaviors Through Hippocampal Gamma Activity. Frontiers in neural circuits. vol 16. 2022-07-25. PMID:35874429. |
glutamatergic projection of the hippocampus to the nucleus accumbens (nac) and dopaminergic transmission in nac is necessary for abnormal behaviors. |
2022-07-25 |
2023-08-14 |
rat |
| Alex B Kawa, Eun-Kyung Hwang, Jonathan R Funke, Hongyi Zhou, Mauro Costa-Mattioli, Marina E Wol. Positive Allosteric Modulation of mGlu Biological psychiatry. 2022-07-23. PMID:35871097. |
expression of incubated cocaine craving depends on elevated calcium-permeable ampa receptors (cp-ampars) on medium spiny neurons in the nucleus accumbens (nac) core. |
2022-07-23 |
2023-08-14 |
Not clear |
| Benjamin Davidson, Peter Giacobbe, Tony P George, Sean M Nestor, Jennifer S Rabin, Maged Goubran, Alexander J Nyman, Anusha Baskaran, Ying Meng, Christopher B Pople, Simon J Graham, Fred Tam, Clement Hamani, Nir Lipsma. Deep brain stimulation of the nucleus accumbens in the treatment of severe alcohol use disorder: a phase I pilot trial. Molecular psychiatry. 2022-07-20. PMID:35858989. |
the symptoms of aud are driven by dysfunction in several neurocircuits centered on the nucleus accumbens (nac). |
2022-07-20 |
2023-08-14 |
Not clear |
| Durairaj Ragu Varman, Padmanabhan Mannangatti, Mark A Subler, Jolene J Windle, Sammanda Ramamoorthy, Lankupalle D Jayanth. Blunted Amphetamine-induced Reinforcing Behaviors and Transporter Downregulation in Knock-in Mice Carrying Alanine Mutations at Threonine-258 and Serine-259 of Norepinephrine Transporter. Journal of molecular neuroscience : MN. 2022-07-19. PMID:35852782. |
net-t258a/s259a mice showed reduced net function in the prefrontal cortex (pfc) compared to wt mice while net function in the nucleus accumbens (nac) remained unchanged. |
2022-07-19 |
2023-08-14 |
mouse |