| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Li, Zhi Chen, Jianting Zhao, Heming Yu, Xiangyu Chen, Yong He, Yu Tian, Yue Wang, Chong Chen, Ke Cheng, Peng Xi. Neurotransmitter and Related Metabolic Profiling in the Nucleus Accumbens of Chronic Unpredictable Mild Stress-Induced Anhedonia-Like Rats. Frontiers in behavioral neuroscience. vol 16. 2022-05-16. PMID:35571281. |
anhedonia, as a core symptom, was closely associated with altered levels of 5-hydroxytryptamine (5-ht), dopamine (da), and diverse types of glutamate (glu) receptors in the nucleus accumbens (nac). |
2022-05-16 |
2023-08-13 |
rat |
| Darius D Becker-Krail, William H Walker, Randy J Nelso. The Ventral Tegmental Area and Nucleus Accumbens as Circadian Oscillators: Implications for Drug Abuse and Substance Use Disorders. Frontiers in physiology. vol 13. 2022-05-16. PMID:35574492. |
in this review, we present the most recent evidence for the ventral tegmental area (vta) and nucleus accumbens (nac) to serve as extra-scn oscillators and highlight studies that illustrate the functional significance of the vta's and nac's inherent circadian properties as they relate to reward-processing, drug abuse, and vulnerability to develop substance use disorders (suds). |
2022-05-16 |
2023-08-13 |
Not clear |
| Tomasz Gos, Johann Steiner, Kurt Trübner, Marta Krzyżanowska, Michał Kalisza. Ribosomal DNA transcription is increased in the left nucleus accumbens of heroin-dependent males. European archives of psychiatry and clinical neuroscience. 2022-05-14. PMID:35567616. |
the nucleus accumbens (nac) plays an outstanding neurobiological role in opioid addiction as a part of the striatum and key component of brain reward system. |
2022-05-14 |
2023-08-13 |
human |
| Maxine K Loh, J Amiel Rosenkran. The medial orbitofrontal cortex governs reward-related circuits in an age-dependent manner. Cerebral cortex (New York, N.Y. : 1991). 2022-05-13. PMID:35551358. |
nucleus accumbens (nac) neurons integrate excitatory inputs from cortical and limbic structures, contributing to critical cognitive functions, including decision-making. |
2022-05-13 |
2023-08-13 |
rat |
| Kerri D Pryce, Aarthi Ramakrishnan, Hope Kronnman, Andrew Nicolais, Claire Polizu, Anne Ruiz, Randal Serafini, Sevasti Gaspari, Catherine J Pena, Angelica Torres-Berrio, Vassiliki Mitsi, Matthew Darpe, L I Shen, Eric J Nestler, Venetia Zachario. A novel HDAC1/2 inhibitor alleviates physical and emotional symptoms associated with spontaneous oxycodone withdrawal in neuropathic pain mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552957. |
rna-sequencing (rna-seq) and bioinformatic analyses revealed that oxycodone withdrawal alone triggers robust gene expression adaptations in the nucleus accumbens (nac), medial prefrontal cortex (mpfc), and ventral tegmental area (vta), with numerous genes and pathways selectively affected by oxycodone withdrawal under peripheral nerve injury states. |
2022-05-13 |
2023-08-13 |
mouse |
| Cristina M Rivera-Quiles, Milagros Alday, Michelle Mazei-Robiso. Role of Neuromedin S-expressing Ventral Tegmental Area Neurons in Morphine Behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35553972. |
neuromedin u receptor 2 (nmur2), the receptor with which nms interacts, is expressed within target regions of vta da neurons, like the nucleus accumbens (nac). |
2022-05-13 |
2023-08-13 |
Not clear |
| Melody C-L Iacino, Taylor A Stowe, Elizabeth G Pitts, Mark J Ferri. Diurnal Variation in Motivation, Cocaine Value, and In Vivo Dopamine Release. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35553974. |
we hypothesize that the degree to which the magnitude of mesolimbic da release in the nucleus accumbens (nac) varies across time will correspond diurnal variations found in motivation to take cocaine. |
2022-05-13 |
2023-08-13 |
rat |
| Alexander D Maitland, Carrie R Ferrari. Effect of rate of intravenous cocaine infusion on psychomotor sensitization and striatal AMPAR expression in female rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554015. |
furthermore, increases in cell-surface expression of ampa-type glutamate receptors within the nucleus accumbens (nac) are associated with psychomotor sensitization and enhanced cocaine-seeking, but potential effects of roi on nac glutamate plasticity had not been examined. |
2022-05-13 |
2023-08-13 |
rat |
| Chelsea Brown, Jackie Beltran, Elissa Fultz, Tori Tran, Brooke Barger, Nyssa Williams, Waylon Yen, Asher Park, Tod Kippin, Karen Szumlinsk. Investigating the Role of Corticostriatal Glutamate Signaling in Methamphetamine Reward and Reinforcement. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554032. |
while the majority of addiction research has implicated the dopamine system, the long-term neuroplasticity that maintains ma use disorder also involves drug-induced changes in glutamate signaling in reward regions of the brain like the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2022-05-13 |
2023-08-13 |
Not clear |
| Kimberly Thibeault, Alberto Lopez, Joseph Dryer, Veronika Kondev, Sachin Patel, Cody Siciliano, Erin Calipar. Characterizing the transcriptionally-activated ensembles recruited by cocaine in the nucleus accumbens. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554570. |
here we aimed to determine if ensembles transcriptionally activated by cocaine in the nucleus accumbens (nac) - a brain region central to reward encoding - were capable of driving motivated behaviors in isolation. |
2022-05-13 |
2023-08-13 |
mouse |
| Jacqueline Silva, Stephanea Stocheff, Christina Merritt, Andrew Routh, Noelle Anastasio, Kathryn Cunningha. Transcriptomic Profiling Reveals Mesolimbic Gene Targets Associated with Oxycodone-Seeking During Abstinence. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555943. |
cellular adaptations within the mesolimbic dopaminergic pathway from the ventral tegmental area (vta) to the nucleus accumbens (nac) are important in driving sensitivity to drug-associated cues and relapse to drug consumption. |
2022-05-13 |
2023-08-13 |
Not clear |
| Yibin Xu, Stacia Lewandowski, Christina Besad. Allosteric Dopamine transporter modulator inhibits cocaine-induced behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555950. |
to test if km822 has similar effects in mammals, we administered km822 and cocaine through intracranial infusions into long evans rats' nucleus accumbens (nac) and measured locomotion. |
2022-05-13 |
2023-08-13 |
rat |
| Suzannah De Almeida, Gregory Sarto. BET proteins as novel epigenetic targets for the treatment of Opioid Use Disorder. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555955. |
to assess a potential role for bet proteins in oud, we measured time-dependent changes in bet mrna expression in the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds), following oral oxycodone self-administration. |
2022-05-13 |
2023-08-13 |
mouse |
| Lillian J Brady, Kimberly C Thibeault, Alberto J Lopez, Jennifer J Tat, Suzanne O Nolan, Cody A Siciliano, Erin S Calipar. Sex-specific cholinergic regulation of dopamine release mechanisms through nicotinic receptors in the nucleus accumbens. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556654. |
at the hub of female vulnerability to sud is significant dysfunction in the mesolimbic dopamine system connecting the ventral tegmental area (vta) to the nucleus accumbens (nac). |
2022-05-13 |
2023-08-13 |
mouse |
| Amy Leach, Mark Ferri. Selective Optogenetic Dopamine Terminal Stimulation Reveals Role of GABAergic Signaling in Individual Differences in Dopamine Release. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556748. |
dopamine release dynamics are tightly controlled by local modulation within the nucleus accumbens (nac), including by nicotinic acetylcholine receptors (nachrs), but the mechanisms by which this local modulation may contribute to differential da release is not fully understood. |
2022-05-13 |
2023-08-13 |
rat |
| Michael Z Leonard, Klaus A Micze. Cues Associated with Social Defeat Stress Recruit CRF in the Nucleus Accumbens and Invigorate Drug-Seeking following Abstinence from Cocaine. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556987. |
in rats, crf enhances instrumental behavior directed towards gaining access to cocaine, in part through local control of da transmission in the nucleus accumbens (nac). |
2022-05-13 |
2023-08-13 |
rat |
| Stefany D Primeau. Intake of High Fat Diet leads to Over-expression of CD36, QRFP and QRFPr in the Gustatory Neural Circuit. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560813. |
therefore, the goal of the current study was to conduct a time course analysis of continuous access to hfd on neural markers of food intake, including qrfp in the mbh and its receptor, qrfpr, in the nucleus accumbens (nac). |
2022-05-13 |
2023-08-13 |
rat |
| Ming Lin, Jiamin Xu, Xi Liu, Zhenfeng Dai, Zhimin Liu, Xin Zhao, Yi Sun, Xiaoping P. Metabolomics profiling of methamphetamine addicted human serum and three rat brain areas. RSC advances. vol 9. issue 70. 2022-05-11. PMID:35540062. |
by using maldi-msi, the relative quantification and distribution of 14 metabolites were investigated in the nucleus accumbens (nac), dorsal hippocampus (dhpc) and ventral hippocampus (vhpc) of cpp rat brain. |
2022-05-11 |
2023-08-13 |
human |
| Dennis A Burke, Veronica A Alvare. Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports. vol 39. issue 6. 2022-05-11. PMID:35545050. |
dopamine modulation of nucleus accumbens (nac) circuitry is central to theories of reward seeking and reinforcement learning. |
2022-05-11 |
2023-08-13 |
mouse |
| Joshua P Aronson, Husam A Katnani, Anna Huguenard, Graham Mulvaney, Edward R Bader, Jimmy C Yang, Emad N Eskanda. Phasic stimulation in the nucleus accumbens enhances learning after traumatic brain injury. Cerebral cortex communications. vol 3. issue 2. 2022-05-09. PMID:35529519. |
here, we investigated task-matched deep-brain stimulation of the nucleus accumbens (nac) to augment reinforcement learning in a rodent model of tbi. |
2022-05-09 |
2023-08-13 |
Not clear |