| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Fiserová, S Consolo, M Krsia. Chronic morphine induces long-lasting changes in acetylcholine release in rat nucleus accumbens core and shell: an in vivo microdialysis study. Psychopharmacology. vol 142. issue 1. 1999-05-26. PMID:10102787. |
acute administration of morphine dose-dependently decreased acetylcholine (ach) release in the nucleus accumbens (nac), with 10 mg/kg s.c. being most effective, 5 mg/kg ineffective. |
1999-05-26 |
2023-08-12 |
rat |
| F I Tarazi, A Campbell, R J Baldessarin. Effects of hippocampal lesions on striatolimbic ionotropic glutamatergic receptors. Neuroscience letters. vol 250. issue 1. 1999-05-19. PMID:9696054. |
changes in ionotropic n-methyl-d-aspartate (nmda), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) and kainate glutamatergic (glu) receptor binding in rat caudate putamen (cpu) and nucleus accumbens (nac) and hippocampal ca1 and ca3 regions were examined after unilateral injections of kainic acid (ka) into hippocampus to degenerate local intrinsic neurons and remove the glutamatergic afferents projecting to cpu and nac. |
1999-05-19 |
2023-08-12 |
rat |
| G M Potter, A Moshirfar, T W Castongua. Insulin affects dopamine overflow in the nucleus accumbens and the striatum. Physiology & behavior. vol 65. issue 4-5. 1999-05-17. PMID:10073485. |
to better characterize the central nervous system response to peripheral insulin administration, male sprague-dawley rats were fitted with microdialysis probes in the nucleus accumbens (nac; n = 23) and striatum (str; n = 22). |
1999-05-17 |
2023-08-12 |
rat |
| S L Dewey, J D Brodie, M Gerasimov, B Horan, E L Gardner, C R Ashb. A pharmacologic strategy for the treatment of nicotine addiction. Synapse (New York, N.Y.). vol 31. issue 1. 1999-05-04. PMID:10025686. |
like many psychostimulant drugs, nicotine elevates extracellular and synaptic dopamine (da) concentrations in the nucleus accumbens (nac). |
1999-05-04 |
2023-08-12 |
Not clear |
| B K Tolliver, A H Newman, J L Katz, L B Ho, L M Fox, K Hsu, S P Berge. Behavioral and neurochemical effects of the dopamine transporter ligand 4-chlorobenztropine alone and in combination with cocaine in vivo. The Journal of pharmacology and experimental therapeutics. vol 289. issue 1. 1999-04-21. PMID:10086994. |
the current studies evaluated the novel diphenylmethoxytropane analog 4-chlorobenztropine (4-cl-bzt), cocaine, and combinations of the two drugs for their abilities to stimulate locomotor activity, produce cocaine-like discriminative stimulus effects, and elevate extracellular dopamine (da) in the nucleus accumbens (nac) as measured by in vivo microdialysis. |
1999-04-21 |
2023-08-12 |
rat |
| E V Gurevich, J W Himes, J N Joyc. Developmental regulation of expression of the D3 dopamine receptor in rat nucleus accumbens and islands of Calleja. The Journal of pharmacology and experimental therapeutics. vol 289. issue 1. 1999-04-21. PMID:10087054. |
we studied developmental expression of d3r in the rat nucleus accumbens (nac) and islands of calleja (isc). |
1999-04-21 |
2023-08-12 |
rat |
| P H Janak, J Y Chang, D J Woodwar. Neuronal spike activity in the nucleus accumbens of behaving rats during ethanol self-administration. Brain research. vol 817. issue 1-2. 1999-03-12. PMID:9889360. |
many lines of evidence support the importance of the nucleus accumbens (nac) for ethanol-reinforced behavior. |
1999-03-12 |
2023-08-12 |
rat |
| D J Henry, X T Hu, F J Whit. Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860115. |
among the adaptations implicated in cocaine sensitization are transient subsensitivity of impulse-regulating da d2 autoreceptors on ventral tegmental area (vta) da neurons leading to hyperactivity of the mesoaccumbens da pathway, and persistently enhanced da d1 receptor responses of nucleus accumbens (nac) neurons. |
1999-02-25 |
2023-08-12 |
rat |
| T Kuroki, H Y Meltzer, J Ichikaw. Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 288. issue 2. 1999-02-22. PMID:9918588. |
the present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (da) levels in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), using in vivo microdialysis with dual probe implantation in awake, freely moving rats. |
1999-02-22 |
2023-08-12 |
rat |
| N Thiriet, N Humblot, C Burgun, D Aunis, J Zwille. Cocaine and fluoxetine induce the expression of the hVH-5 gene encoding a MAP kinase phosphatase. Brain research. Molecular brain research. vol 62. issue 2. 1999-02-18. PMID:9813294. |
injection of cocaine, amphetamine and caffeine induced hvh-5 mrna expression within 40 min in the nucleus accumbens (nac), caudate putamen, frontal cortex and hippocampus, with a maximal effect in the nac. |
1999-02-18 |
2023-08-12 |
rat |
| I Weiner, J Feldon, R Tarrasch, I Hairston, D Joe. Fimbria-fornix cut affects spontaneous activity, two-way avoidance and delayed non matching to sample, but not latent inhibition. Behavioural brain research. vol 96. issue 1-2. 1999-02-05. PMID:9821543. |
based on evidence pointing to the involvement of the hippocampus and the nucleus accumbens (nac) in li disruption, it has been proposed that li depends on the integrity of the subicular input to the nac. |
1999-02-05 |
2023-08-12 |
Not clear |
| S E Hemby, C Co, S I Dworkin, J E Smit. Synergistic elevations in nucleus accumbens extracellular dopamine concentrations during self-administration of cocaine/heroin combinations (Speedball) in rats. The Journal of pharmacology and experimental therapeutics. vol 288. issue 1. 1999-02-05. PMID:9862781. |
several studies suggest dopaminergic innervations of the nucleus accumbens (nac) have a central role in the brain processes underlying drug reinforcement. |
1999-02-05 |
2023-08-12 |
rat |
| D F Fiorino, A G Phillip. Facilitation of sexual behavior and enhanced dopamine efflux in the nucleus accumbens of male rats after D-amphetamine-induced behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 1. 1999-02-05. PMID:9870973. |
the present microdialysis study investigated the effect of d-amphetamine-induced sensitization on dopamine (da) efflux in the nucleus accumbens (nac) of male rats during sexual behavior. |
1999-02-05 |
2023-08-12 |
rat |
| R Nadal, A M Chappell, H H Samso. Effects of nicotine and mecamylamine microinjections into the nucleus accumbens on ethanol and sucrose self-administration. Alcoholism, clinical and experimental research. vol 22. issue 6. 1999-01-04. PMID:9756032. |
although the mesolimbic dopamine systems are known to be involved in the reinforcing effects of etoh, the role of nicotinic receptors within the nucleus accumbens (nac) in etoh reinforcement has not been studied. |
1999-01-04 |
2023-08-12 |
rat |
| C A Heidbreder, S Schenk, B Partridge, T S Shippenber. Increased responsiveness of mesolimbic and mesostriatal dopamine neurons to cocaine following repeated administration of a selective kappa-opioid receptor agonist. Synapse (New York, N.Y.). vol 30. issue 3. 1998-12-28. PMID:9776129. |
accordingly, the present microdialysis study characterized the effects of prior, repeated administration of the selective kappa-opioid receptor agonist u69593 on basal and cocaine-evoked da levels within the nucleus accumbens (nac) and caudate putamen (cpu). |
1998-12-28 |
2023-08-12 |
rat |
| G Panagis, A Kastellakis, C Spyrak. Involvement of the ventral tegmental area opiate receptors in self-stimulation elicited from the ventral pallidum. Psychopharmacology. vol 139. issue 3. 1998-12-28. PMID:9784077. |
three additional groups were implanted with guide cannulae in the nucleus accumbens (nac), the ventral tegmental area (vta) or dorsally to the vta and received microinjections of morphine (vehicle: 1.25; 2.50; 5.0; 10.0 microg/0.5 microl per side). |
1998-12-28 |
2023-08-12 |
rat |
| R C Huang, J Y Li. Voltage- and use-dependent inhibition by amphetamine of field potentials and Na+ current in rat nucleus accumbens neurons. Neuroscience letters. vol 252. issue 1. 1998-11-25. PMID:9756360. |
here we demonstrate direct amph inhibition of field potentials and na+ currents in rat nucleus accumbens (nac) neurons. |
1998-11-25 |
2023-08-12 |
rat |
| F I Tarazi, E C Tomasini, R J Baldessarin. Postnatal development of dopamine D4-like receptors in rat forebrain regions: comparison with D2-like receptors. Brain research. Developmental brain research. vol 110. issue 2. 1998-11-17. PMID:9748595. |
development of dopamine d4-like receptors in rat caudate-putamen (cpu), nucleus accumbens (nac), frontal cortex, hippocampus, and entorhinal cortex was assessed at seven points between postnatal days 7 and 60 by computed in vitro receptor autoradiography, and compared with dopamine (da) d2-like receptors. |
1998-11-17 |
2023-08-12 |
rat |
| D A Baker, R A Fuchs, S E Specio, T V Khroyan, J L Neisewande. Effects of intraaccumbens administration of SCH-23390 on cocaine-induced locomotion and conditioned place preference. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723788. |
after behavioral testing was completed, animals were injected with their respective dose of sch-23390 into the nucleus accumbens (nac), followed by a systemic injection of the irreversible antagonist n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (eedq). |
1998-11-16 |
2023-08-12 |
rat |
| J L Neisewander, R A Fuchs, L E O'Dell, T V Khroya. Effects of SCH-23390 on dopamine D1 receptor occupancy and locomotion produced by intraaccumbens cocaine infusion. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723789. |
in experiment 2, rats received coinfusion of sch-23390 (0-1 microg/side) and cocaine (0 or 100 microg/side) into the nucleus accumbens (nac). |
1998-11-16 |
2023-08-12 |
rat |