| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Tomie, A S Aguado, L A Pohorecky, D Benjami. Individual differences in pavlovian autoshaping of lever pressing in rats predict stress-induced corticosterone release and mesolimbic levels of monoamines. Pharmacology, biochemistry, and behavior. vol 65. issue 3. 2000-03-27. PMID:10683492. |
tail-blood samples were obtained before and after the 20th autoshaping session, then 24 h later the rats were sacrificed and dissection yielded tissue samples of nucleus accumbens (nac), prefrontal cortex (pfc), caudate putamen (cp), and ventral tegmental area (vta). |
2000-03-27 |
2023-08-12 |
rat |
| L F Callado, S E Hopwood, P J Hancock, J A Stamfor. Effects of dizocilpine (MK 801) on noradrenaline, serotonin and dopamine release and uptake. Neuroreport. vol 11. issue 1. 2000-03-16. PMID:10683852. |
in the present study, we examined the actions of the nmda antagonist dizocilpine (mk801) on electrically evoked release and uptake of noradrenaline (na) in the locus coeruleus (lc), serotonin (5-ht) in the dorsal raphe nucleus (drn) and dopamine (da) in the nucleus accumbens (nac), measured by fast cyclic voltammetry (fcv) in rat brain slices. |
2000-03-16 |
2023-08-12 |
rat |
| P Brown, M E Mollive. Dual serotonin (5-HT) projections to the nucleus accumbens core and shell: relation of the 5-HT transporter to amphetamine-induced neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 5. 2000-03-09. PMID:10684896. |
dopamine release in the nucleus accumbens (nac) has been implicated as mediating the rewarding effects of stimulant drugs; however, recent studies suggest that 5-ht release may also contribute. |
2000-03-09 |
2023-08-12 |
rat |
| Q S Ya. Activation of 5-HT2A/2C receptors within the nucleus accumbens increases local dopaminergic transmission. Brain research bulletin. vol 51. issue 1. 2000-02-18. PMID:10654584. |
this study was designed to assess the involvement of the 5-hydroxytryptamine (5-ht)2a/2c receptor subtypes in the regulation of in vivo dopamine release in the rat nucleus accumbens (nac). |
2000-02-18 |
2023-08-12 |
rat |
| S F Ali, N Thiriet, J Zwille. Acute ibogaine injection induces expression of the immediate early genes, egr-1 and c-fos, in mouse brain. Brain research. Molecular brain research. vol 74. issue 1-2. 2000-02-15. PMID:10640697. |
a single injection of ibo produced a significant increase of egr-1 messenger rna induction in nucleus accumbens (nac), caudate-putamen (cpu), frontal cortex (fcx), septum, dentate gyrus (dg) and ca3 region of hippocampus, whereas c-fos gene was induced in cpu, fcx, dg, septum and ca1 region of hippocampus. |
2000-02-15 |
2023-08-12 |
mouse |
| G Di Chiara, P Loddo, G Tand. Reciprocal changes in prefrontal and limbic dopamine responsiveness to aversive and rewarding stimuli after chronic mild stress: implications for the psychobiology of depression. Biological psychiatry. vol 46. issue 12. 2000-02-08. PMID:10624543. |
to investigate the role in depression of phasic dopamine transmission in cortical and limbic areas, we studied the effect of cms on the responsiveness of dopamine (da) transmission to aversive and rewarding stimuli in rats by microdialysis of the nucleus accumbens (nac) shell and of the medial prefrontal cortex (pfcx). |
2000-02-08 |
2023-08-12 |
human |
| D Paredes, P Rada, E Bonilla, L E Gonzalez, M Parada, L Hernande. Melatonin acts on the nucleus accumbens to increase acetylcholine release and modify the motor activity pattern of rats. Brain research. vol 850. issue 1-2. 2000-02-03. PMID:10629744. |
brain microdialysis coupled to high performance liquid chromatography with electrochemical detection (hplc-ed) was used to evaluate the influence of melatonin on extracellular concentration of acetylcholine (ach) in the nucleus accumbens (nac) of rats. |
2000-02-03 |
2023-08-12 |
rat |
| D Feifel, T L Rez. Effects of neurotensin administered into the ventral tegmental area on prepulse inhibition of startle. Behavioural brain research. vol 106. issue 1-2. 2000-01-11. PMID:10595435. |
neurotensin receptors have been identified in the nucleus accumbens (nac) and ventral tegmental area (vta). |
2000-01-11 |
2023-08-12 |
Not clear |
| J J Rodríguez, D R Garcia, V M Picke. Subcellular distribution of 5-hydroxytryptamine2A and N-methyl-D-aspartate receptors within single neurons in rat motor and limbic striatum. The Journal of comparative neurology. vol 413. issue 2. 1999-12-21. PMID:10524335. |
the dorsolateral caudate-putamen nucleus (cpn) and the nucleus accumbens (nac) shell, respectively, are involved in many motor and limbic functions that are affected by activation of the 5-hydroxytryptamine2a receptor (5ht2ar) and the n-methyl-d-aspartate subtype of glutamate receptor (nmdar). |
1999-12-21 |
2023-08-12 |
rat |
| J Ichikawa, H Y Meltze. The effect of ipsapirone and S(-)-pindolol on dopamine release in rat striatum and nucleus accumbens. Brain research. vol 842. issue 2. 1999-12-21. PMID:10526141. |
however, studies of the role of 5-ht(1a) receptor agonism in the ability of these drugs to modulate dopamine (da) release in the nucleus accumbens (nac), which may be relevant to antipsychotic action, are lacking. |
1999-12-21 |
2023-08-12 |
rat |
| J Ichikawa, H Y Meltze. R(+)-8-OH-DPAT, a serotonin(1A) receptor agonist, potentiated S(-)-sulpiride-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens but not striatum. The Journal of pharmacology and experimental therapeutics. vol 291. issue 3. 1999-12-20. PMID:10565846. |
the serotonin (5-ht)(2a/2c) receptor antagonist ritanserin has been reported to potentiate the dopamine (da) d(2/3) receptor antagonist raclopride-induced da release in medial prefrontal cortex (mpfc) and nucleus accumbens (nac) but not striatum (str). |
1999-12-20 |
2023-08-12 |
rat |
| V Bashkatova, M Kraus, H Prast, A Vanin, K Rayevsky, A Philipp. Influence of NOS inhibitors on changes in ACH release and NO level in the brain elicited by amphetamine neurotoxicity. Neuroreport. vol 10. issue 15. 1999-12-15. PMID:10574552. |
we studied the possible role of neurotoxicity in the d,l-amphetamine (amph)-induced release of acetylcholine (ach) in the nucleus accumbens (nac) and the involvement of endogenous no in this process. |
1999-12-15 |
2023-08-12 |
Not clear |
| Y Li, X T Hu, T G Berney, A J Vartanian, C D Stine, M E Wolf, F J Whit. Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations. Synapse (New York, N.Y.). vol 34. issue 3. 1999-12-10. PMID:10523754. |
behavioral sensitization to psychomotor stimulants is accompanied by a number of alterations in the mesoaccumbens dopamine (da) system, including da autoreceptor subsensitivity in the ventral tegmental area (vta) and da d1 receptor supersensitivity in the nucleus accumbens (nac). |
1999-12-10 |
2023-08-12 |
rat |
| A Rosin, S Lindholm, J Franck, J Georgiev. Downregulation of kappa opioid receptor mRNA levels by chronic ethanol and repetitive cocaine in rat ventral tegmentum and nucleus accumbens. Neuroscience letters. vol 275. issue 1. 1999-11-15. PMID:10554970. |
here, the effects of separately and concurrently administered ethanol and 'binge' cocaine on kappa opioid receptor (kor) mrna in the ventral tegmental area (vta) and nucleus accumbens (nac) of rats were studied. |
1999-11-15 |
2023-08-12 |
human |
| Q S Ya. Extracellular dopamine and serotonin after ethanol monitored with 5-minute microdialysis. Alcohol (Fayetteville, N.Y.). vol 19. issue 1. 1999-11-02. PMID:10487381. |
ethanol at the doses of 0.5, 1, and 2 g/kg was administered ip and extracellular da and 5-ht in 5-min dialysates from the nucleus accumbens (nac) of freely moving rats were determined. |
1999-11-02 |
2023-08-12 |
rat |
| M R Gerasimov, C R Ashby, E L Gardner, M J Mills, J D Brodie, S L Dewe. Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. Synapse (New York, N.Y.). vol 34. issue 1. 1999-10-20. PMID:10459167. |
we examined the acute effect of the irreversible gaba-transaminase inhibitor, gamma-vinyl gaba (gvg, sabril((r)), vigabatrin((r))) on increases in nucleus accumbens (nac) dopamine (da) following acute administration of methamphetamine, heroin, or ethanol. |
1999-10-20 |
2023-08-12 |
Not clear |
| L R McMahon, K A Cunningha. Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell. The Journal of pharmacology and experimental therapeutics. vol 291. issue 1. 1999-10-12. PMID:10490917. |
to test the hypothesis that cocaine-elicited behaviors were modulated by 5-ht(4) receptors in the nucleus accumbens (nac) shell, two separate groups of male rats were implanted with bilateral cannulas aimed at the nac shell. |
1999-10-12 |
2023-08-12 |
rat |
| B E Hildebrand, G Panagis, T H Svensson, G G Nomiko. Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 4. 1999-10-08. PMID:10481840. |
the nachr antagonist mecamylamine administered systemically in chronically nicotine-treated rats elicits a behavioral withdrawal syndrome concomitant with a reduced da output in the nucleus accumbens (nac). |
1999-10-08 |
2023-08-12 |
rat |
| R D Myers, D E Robinso. Mmu and D2 receptor antisense oligonucleotides injected in nucleus accumbens suppress high alcohol intake in genetic drinking HEP rats. Alcohol (Fayetteville, N.Y.). vol 18. issue 2-3. 1999-10-07. PMID:10456575. |
a guide cannula for a microinjection needle was first implanted bilaterally above the nucleus accumbens (nac) of each rat. |
1999-10-07 |
2023-08-12 |
rat |
| J B Atkins, J Chlan-Fourney, H E Nye, N Hiroi, W A Carlezon, E J Nestle. Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs. Synapse (New York, N.Y.). vol 33. issue 2. 1999-09-27. PMID:10400890. |
a smaller induction was seen in the nucleus accumbens (nac) and prefrontal cortex (pfc), brain regions associated with the antipsychotic effects of the drug. |
1999-09-27 |
2023-08-12 |
Not clear |