| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E F Schmidt, M A Sutton, C A Schad, D A Karanian, E S Brodkin, D W Sel. Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 7. 2001-06-28. PMID:11264329. |
in this study, 12 d of cocaine self-administration in rats (4 hr/d) reduced th immunoreactivity by 29% in the nucleus accumbens (nac) shell, but not core, after a 1 week withdrawal period. |
2001-06-28 |
2023-08-12 |
rat |
| Z T Zhu, W R Wu, Y Fu, G Z Ji. I-stepholidine facilitates inhibition of mPFC DA receptors on subcortical NAc DA release. Acta pharmacologica Sinica. vol 21. issue 7. 2001-06-28. PMID:11360679. |
to determine whether the d1 agonistic action of (-)-stepholidine (spd) on the medial prefrontal cortex (mpfc) neuron is involved in the modulation of evoked subcortical dopamine (da) release from nucleus accumbens (nac) of rats. |
2001-06-28 |
2023-08-12 |
rat |
| P Devoto, G Flore, A Ibba, W Fratta, L Pan. Lead intoxication during intrauterine life and lactation but not during adulthood reduces nucleus accumbens dopamine release as studied by brain microdialysis. Toxicology letters. vol 121. issue 3. 2001-06-21. PMID:11369474. |
at the 13th week of age, the functional activity of the nucleus accumbens (nac) dopaminergic system was studied by means of transversal microdialysis. |
2001-06-21 |
2023-08-12 |
rat |
| S B Floresco, C D Blaha, C R Yang, A G Phillip. Modulation of hippocampal and amygdalar-evoked activity of nucleus accumbens neurons by dopamine: cellular mechanisms of input selection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 8. 2001-06-07. PMID:11306637. |
inputs from multiple sites in the telencephalon, including the hippocampus and basolateral amygdala (bla), converge on neurons in the nucleus accumbens (nac), and dopamine (da) is believed to play an essential role in the amplification and gating of these different limbic inputs. |
2001-06-07 |
2023-08-12 |
Not clear |
| F I Tarazi, K Zhang, R J Baldessarin. Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drug treatment. The Journal of pharmacology and experimental therapeutics. vol 297. issue 2. 2001-05-21. PMID:11303062. |
olanzapine and risperidone, but not quetiapine, significantly increased d(2) binding in medial prefrontal cortex (mpc; 67% and 34%), caudate-putamen (cpu; average 42%, 25%), nucleus accumbens (nac; 37%, 28%), and hippocampus (hip; 53%, 30%). |
2001-05-21 |
2023-08-12 |
rat |
| U Krügel, H Kittner, P Ille. Mechanisms of adenosine 5'-triphosphate-induced dopamine release in the rat nucleus accumbens in vivo. Synapse (New York, N.Y.). vol 39. issue 3. 2001-05-10. PMID:11169771. |
the endogenous mechanisms modulating atp-induced dopamine release in the nucleus accumbens (nac) were studied by microdialysis in freely moving rats. |
2001-05-10 |
2023-08-12 |
rat |
| M M Marcus, J M Mathé, G G Nomikos, T H Svensso. Effects of competitive and non-competitive NMDA receptor antagonists on dopamine output in the shell and core subdivisions of the nucleus accumbens. Neuropharmacology. vol 40. issue 4. 2001-05-10. PMID:11249957. |
the effects of acute intravenous administration of the non-competitive nmda receptor antagonists, phencyclidine (pcp), dizocilpine (mk-801; (+)-5-methyl-10,11-dihydroxy-5h-dibenzo(a,b)cyclohepten-5,10-imine), and the competitive nmda receptor antagonist cgp 39551 (dl-(e)-2-amino-4-methyl-5-phosphono-3-pentanoic acid) on extracellular dopamine concentrations were analyzed in the shell and core subdivisions of the nucleus accumbens (nac), associated with limbic and motor functions, respectively. |
2001-05-10 |
2023-08-12 |
rat |
| C D Stine, W Lu, M E Wol. Expression of AMPA receptor flip and flop mRNAs in the nucleus accumbens and prefrontal cortex after neonatal ventral hippocampal lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 3. 2001-04-19. PMID:11166516. |
the present study examined alpha-amino-3-hydroxy-5-methylisoxazole- 4-priopionate (ampa) receptor expression in the prefrontal cortex (pfc) and nucleus accumbens (nac) using a rat model of schizophrenia in which excitotoxic lesions of ventral hippocampus (vh) on postnatal day (pd) 7 lead to the postpubertal emergence of behavioral abnormalities that resemble schizophrenic symptoms. |
2001-04-19 |
2023-08-12 |
rat |
| V David, L H Gold, G F Koob, P Cazal. Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 3. 2001-04-19. PMID:11166520. |
to test the hypothesis that injections directly into a reward-relevant brain region might support consistent cocaine-seeking behavior, balb/cbyj mice implanted in the nucleus accumbens (nac) or the caudate-putamen nucleus (cpu) were trained to discriminate between the arm enabling a microinjection of cocaine (30 pmol/50 nl or 150 pmol/50 nl) and the neutral arm of a y-maze. |
2001-04-19 |
2023-08-12 |
mouse |
| J J Rodríguez, D R Garcia, Y Nakabeppu, V M Picke. FosB in rat striatum: normal regional distribution and enhanced expression after 6-month haloperidol administration. Synapse (New York, N.Y.). vol 39. issue 2. 2001-04-19. PMID:11180499. |
the nucleus accumbens (nac) core also serving motor functions had a higher basal expression than the limbic shell region in control animals. |
2001-04-19 |
2023-08-12 |
rat |
| M E Jackson, B Moghadda. Amygdala regulation of nucleus accumbens dopamine output is governed by the prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 2. 2001-04-05. PMID:11160446. |
a dynamic interaction between the prefrontal cortex (pfc), amygdala, and nucleus accumbens (nac) may be fundamental to regulation of goal-directed behavior by affective and cognitive processes. |
2001-04-05 |
2023-08-12 |
rat |
| Z D You, J H Li, C Y Song, C H Wang, C L L. Chronic morphine treatment inhibits oxytocin synthesis in rats. Neuroreport. vol 11. issue 14. 2001-02-22. PMID:11043533. |
after chronic administration of morphine, the oxytocin content in supraoptic nucleus (son) and nucleus accumbens (nac) decreased, and increased in the ventral tegment area (vta) and locus coeruleus (lc), but did not change in other nuclei including the paraventricular nucleus (pvn), lateral septum (septum), raphe magnus nucleus (nrm) and periaquaductal gray (pag). |
2001-02-22 |
2023-08-12 |
rat |
| A M van Erp, K A Micze. Aggressive behavior, increased accumbal dopamine, and decreased cortical serotonin in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11125011. |
male long-evans rats were implanted with a microdialysis probe aimed at the nucleus accumbens (nac) or medial prefrontal cortex (pfc); next, 10 min samples were collected before, during, and after a 10 min confrontation. |
2001-02-22 |
2023-08-12 |
rat |
| B E Hildebrand, T H Svensso. Intraaccumbal mecamylamine infusion does not affect dopamine output in the nucleus accumbens of chronically nicotine-treated rats. Journal of neural transmission (Vienna, Austria : 1996). vol 107. issue 8-9. 2001-02-15. PMID:11041268. |
recently we have shown that the nicotinic receptor (nachr) antagonist mecamylamine both when administered systemically and locally into the ventral tegmental area (vta) to chronically nicotine-treated rats reduces dopamine (da) output in the nucleus accumbens (nac) and elicits behavioral withdrawal signs. |
2001-02-15 |
2023-08-12 |
rat |
| S Tucci, Q Contreras, X Paez, L Gonzalez, P Rada, L Hernande. Medial prefrontal transection enhances social interaction. II: neurochemical studies. Brain research. vol 887. issue 2. 2001-02-15. PMID:11134614. |
social interaction enhances dopaminergic activity in the nucleus accumbens (nac). |
2001-02-15 |
2023-08-12 |
rat |
| A F Hoffman, C R Lupic. Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids. Journal of neurophysiology. vol 85. issue 1. 2001-02-15. PMID:11152707. |
the nucleus accumbens (nac) represents a critical site for the rewarding and addictive properties of several classes of abused drugs. |
2001-02-15 |
2023-08-12 |
rat |
| K D Carr, G Y Kim, S Cabeza de Vac. Chronic food restriction in rats augments the central rewarding effect of cocaine and the delta1 opioid agonist, DPDPE, but not the delta2 agonist, deltorphin-II. Psychopharmacology. vol 152. issue 2. 2001-02-08. PMID:11057524. |
the increased expression of c-fos in nucleus accumbens (nac) shell, in particular, suggests that food restriction may augment drug reward by modulating dopamine (da) synaptic function in this area. |
2001-02-08 |
2023-08-12 |
rat |
| D Robbe, G Alonso, F Duchamp, J Bockaert, O J Manzon. Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150326. |
despite the role of excitatory transmission to the nucleus accumbens (nac) in the actions of most drugs of abuse, the presence and functions of cannabinoid receptors (cb1) on the glutamatergic cortical afferents to the nac have never been explored. |
2001-02-08 |
2023-08-12 |
mouse |
| A M Himmelheber, J P Bruno, M Sarte. Effects of intra-accumbens infusions of amphetamine or cis-flupenthixol on sustained attention performance in rats. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080543. |
as nucleus accumbens (nac) efferent projections have been hypothesized to modulate the excitability of basal forebrain corticopetal projections, the effects of drug-induced modulation of nac dopaminergic transmission on sustained attention performance in rats were assessed. |
2001-02-02 |
2023-08-12 |
rat |
| Y L Hurd, M Ponté. Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis. Behavioural brain research. vol 116. issue 2. 2001-02-02. PMID:11080549. |
in the present study, the in vivo microdialysis technique was used to directly manipulate extracellular dopamine concentrations in the nucleus accumbens (nac) shell and the amygdala (amy) in rats maintaining stable patterns of cocaine (1.5 mg/kg/infusion) intake under a fixed ratio 1 schedule of reinforcement. |
2001-02-02 |
2023-08-12 |
rat |