| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Thomas, C Beurrier, A Bonci, R C Malenk. Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine. Nature neuroscience. vol 4. issue 12. 2002-01-11. PMID:11694884. |
adaptations in the nucleus accumbens (nac), a component of the mesolimbic dopamine system, are thought to contribute to this behavioral change. |
2002-01-11 |
2023-08-12 |
Not clear |
| T Hikida, S Kaneko, T Isobe, Y Kitabatake, D Watanabe, I Pastan, S Nakanish. Increased sensitivity to cocaine by cholinergic cell ablation in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 23. 2001-12-07. PMID:11606786. |
an important neural substrate for cocaine addiction is the nucleus accumbens (nac), which receives dopaminergic input from the ventral tegmental area. |
2001-12-07 |
2023-08-12 |
mouse |
| M M Kraus, H Pras. The nitric oxide system modulates the in vivo release of acetylcholine in the nucleus accumbens induced by stimulation of the hippocampal fornix/fimbria-projection. The European journal of neuroscience. vol 14. issue 7. 2001-12-07. PMID:11683902. |
nerve signals from the hippocampus to the nucleus accumbens (nac) are transmitted through a glutamatergic pathway via the fornix/fimbria fibres. |
2001-12-07 |
2023-08-12 |
rat |
| P Rada, K Jensen, B G Hoebe. Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens. Psychopharmacology. vol 157. issue 1. 2001-10-25. PMID:11512050. |
prior research suggests that high levels of acetylcholine (ach) in the nucleus accumbens (nac) are associated with aversive states such as morphine withdrawal, but this has not been tested for nicotine withdrawal. |
2001-10-25 |
2023-08-12 |
rat |
| S Papadeas, A C Grobin, A L Morro. Chronic ethanol consumption differentially alters GABA(A) receptor alpha1 and alpha4 subunit peptide expression and GABA(A) receptor-mediated 36 Cl(-) uptake in mesocorticolimbic regions of rat brain. Alcoholism, clinical and experimental research. vol 25. issue 9. 2001-10-25. PMID:11584145. |
recent studies show that chronic ethanol exposure alters subsequent ethanol self-administration, effects that are believed to be mediated by subcortical regions of the rat brain including the amygdala (amg), the nucleus accumbens (nac), and the ventral tegmental area (vta). |
2001-10-25 |
2023-08-12 |
rat |
| L R McMahon, M Filip, K A Cunningha. Differential regulation of the mesoaccumbens circuit by serotonin 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 19. 2001-10-11. PMID:11567068. |
to test this hypothesis, the present study measured cocaine-evoked locomotor activity after bilateral microinjection of selective 5-ht(2a)r and 5-ht(2c)r antagonists into the ventral tegmental area (vta) or the nucleus accumbens (nac) shell. |
2001-10-11 |
2023-08-12 |
Not clear |
| A M Pliakas, R R Carlson, R L Neve, C Konradi, E J Nestler, W A Carlezo. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 18. 2001-10-04. PMID:11549750. |
drugs of abuse regulate the transcription factor camp response element-binding protein (creb) in striatal regions, including the nucleus accumbens (nac). |
2001-10-04 |
2023-08-12 |
rat |
| S Shichinohe, H Ozawa, E Hashimoto, T Tatschner, P Riederer, T Sait. Changes in the cAMP-related signal transduction mechanism in postmortem human brains of heroin addicts. Journal of neural transmission (Vienna, Austria : 1996). vol 108. issue 3. 2001-09-27. PMID:11341485. |
immunoreactivities of adenylyl cyclase (ac) type i (ac-i), and basal, forskolin- and mn2+-stimulated ac activities with or without calcium and calmodulin (ca2+/cam) were estimated in temporal cortex (tc)-and nucleus accumbens (nac) membranes from brains of heroin addicts and controls. |
2001-09-27 |
2023-08-12 |
human |
| M E Alburges, K A Keefe, G R Hanso. Unique responses of limbic met-enkephalin systems to low and high doses of methamphetamine. Brain research. vol 905. issue 1-2. 2001-09-20. PMID:11423086. |
the levels of m-enk were not changed at any of the time points examined in the core of the nucleus accumbens (nac). |
2001-09-20 |
2023-08-12 |
Not clear |
| S Fenu, V Bassareo, G Di Chiar. A role for dopamine D1 receptors of the nucleus accumbens shell in conditioned taste aversion learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 17. 2001-09-20. PMID:11517277. |
sch 39166 impaired cta also when infused in the nucleus accumbens (nac) shell 5 min after the cs. |
2001-09-20 |
2023-08-12 |
Not clear |
| C N Haile, N Hiroi, E J Nestler, T A Koste. Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. Synapse (New York, N.Y.). vol 41. issue 3. 2001-09-13. PMID:11391778. |
we investigated locomotor activity, stereotypy signs, and levels of specific proteins in the nucleus accumbens (nac) and ventral tegmental area (vta) in these strains at baseline and following chronic administration of cocaine (30 mg/kg/day for 14 days). |
2001-09-13 |
2023-08-12 |
rat |
| A Mayerhofer, K A Kovar, W J Schmid. Changes in serotonin, dopamine and noradrenaline levels in striatum and nucleus accumbens after repeated administration of the abused drug MDMA in rats. Neuroscience letters. vol 308. issue 2. 2001-09-13. PMID:11457569. |
in nucleus accumbens (nac), the noradrenaline levels were also decreased, whereas dopamine levels were increased 4 weeks after treatment. |
2001-09-13 |
2023-08-12 |
rat |
| U Krügel, H Kittner, H Franke, P Ille. Stimulation of P2 receptors in the ventral tegmental area enhances dopaminergic mechanisms in vivo. Neuropharmacology. vol 40. issue 8. 2001-09-06. PMID:11406200. |
it has been shown that endogenous adenosine 5'-triphosphate (atp) as well as its exogenously applied structural analogue, 2-methylthio atp (2-mesatp), facilitate the release of dopamine from axon terminals in the rat nucleus accumbens (nac) by activating atp-sensitive p2 receptors. |
2001-09-06 |
2023-08-12 |
rat |
| B Chieng, J M Bekker. Inhibition of calcium channels by opioid- and adenosine-receptor agonists in neurons of the nucleus accumbens. British journal of pharmacology. vol 133. issue 3. 2001-08-30. PMID:11375249. |
the pharmacological effects of opioid- and adenosine-receptor agonists on neural signalling were investigated by measuring drug actions on barium current flowing through calcium channels in acutely-dissociated neurons of the rat nucleus accumbens (nac). |
2001-08-30 |
2023-08-12 |
rat |
| M Giorgetti, G Hotsenpiller, P Ward, T Teppen, M E Wol. Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487659. |
to test this, we used in vivo microdialysis to examine the effects of intra-vta administration of ampa (10 microm) and nmda (100 microm) on dopamine (da) and glutamate efflux in the vta and the nucleus accumbens (nac), an important target of vta da neurons. |
2001-08-30 |
2023-08-12 |
rat |
| S B Floresco, C D Blaha, C R Yang, A G Phillip. Dopamine D1 and NMDA receptors mediate potentiation of basolateral amygdala-evoked firing of nucleus accumbens neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487660. |
interactions between the basolateral amygdala (bla) and the nucleus accumbens (nac) mediate reward-related processes that are modulated by mesoaccumbens dopamine (da) transmission. |
2001-08-30 |
2023-08-12 |
Not clear |
| H C Kim, G Bing, E J Shin, H S Jhoo, M A Cheon, S H Lee, K H Choi, J I Kim, W K Jho. Dextromethorphan affects cocaine-mediated behavioral pattern in parallel with a long-lasting Fos-related antigen-immunoreactivity. Life sciences. vol 69. issue 6. 2001-08-09. PMID:11476183. |
repeated administration with cocaine or dm increased fra-ir in the nucleus accumbens (nac) and striatum which lasted for at least 7 days. |
2001-08-09 |
2023-08-12 |
mouse |
| M Tattoli, R Cagiano, S Gaetani, V Ghiglieri, A Giustino, G Mereu, L Trabace, V Cuom. Neurofunctional effects of developmental alcohol exposure in alcohol-preferring and alcohol-nonpreferring rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 6. 2001-07-19. PMID:11331149. |
neurochemical experiments have shown that basal levels of dopamine (da) and homovanillic acid (hva) were significantly higher in the nucleus accumbens (nac) of sp rats with respect to snp animals. |
2001-07-19 |
2023-08-12 |
rat |
| V M Pickel, J Chan, K T Delle Donne, H Boudin, D Pélaprat, W Rostén. High-affinity neurotensin receptors in the rat nucleus accumbens: subcellular targeting and relation to endogenous ligand. The Journal of comparative neurology. vol 435. issue 2. 2001-07-12. PMID:11391637. |
neurotensin is present in selective mesolimbic dopaminergic projections to the nucleus accumbens (nac) shell but also is synthesized locally in this region and in the motor-associated nac core. |
2001-07-12 |
2023-08-12 |
rat |
| B Roozendaal, D J de Quervain, B Ferry, B Setlow, J L McGaug. Basolateral amygdala-nucleus accumbens interactions in mediating glucocorticoid enhancement of memory consolidation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 7. 2001-06-28. PMID:11264325. |
the bla projects directly to the nucleus accumbens (nac) via this st pathway. |
2001-06-28 |
2023-08-12 |
rat |