| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V M Pickel, J Cha. Ultrastructural localization of the serotonin transporter in limbic and motor compartments of the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 17. 1999-09-23. PMID:10460242. |
extracellular levels of serotonin [5-hydroxytryptamine (5-ht)] in the nucleus accumbens (nac) can influence both cognitive and motor functions involving extensive connections with the frontal cortex. |
1999-09-23 |
2023-08-12 |
rat |
| P J Hancock, J A Stamfor. Stereospecific effects of ketamine on dopamine efflux and uptake in the rat nucleus accumbens. British journal of anaesthesia. vol 82. issue 4. 1999-09-17. PMID:10472231. |
many, if not all, drugs of abuse have been shown to increase dopamine efflux in the nucleus accumbens (nac). |
1999-09-17 |
2023-08-12 |
rat |
| P De Deurwaerdère, U Spampinat. Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation. Journal of neurochemistry. vol 73. issue 3. 1999-09-14. PMID:10461892. |
this study investigates, using in vivo microdialysis, the role of serotonin2a (5-ht2a) and 5-ht(2b/2c) receptors in the effect of dorsal raphe nucleus (drn) electrical stimulation on dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), and 5-hydroxyindoleacetic acid (5-hiaa) extracellular levels monitored in the nucleus accumbens (nac) and the striatum of halothane-anesthetized rats. |
1999-09-14 |
2023-08-12 |
rat |
| D A Cory-Slechta, D J O'Mara, B J Brocke. Learning versus performance impairments following regional administration of MK-801 into nucleus accumbens and dorsomedial striatum. Behavioural brain research. vol 102. issue 1-2. 1999-09-10. PMID:10403026. |
to further ascertain the relative contributions of nucleus accumbens (nac) and dorsomedial striatum (ds) to cognitive behaviors, the comparative effects in rats of mk-801 microinjections into these regions on a multiple schedule of repeated learning (rl) and performance (p) were examined. |
1999-09-10 |
2023-08-12 |
rat |
| W J McBride, J M Murphy, S Ikemot. Localization of brain reinforcement mechanisms: intracranial self-administration and intracranial place-conditioning studies. Behavioural brain research. vol 101. issue 2. 1999-08-23. PMID:10372570. |
activation of the vta dopamine (da) system may produce reinforcing effects in general because (a) neurotensin is self-administered into the vta, and injection of neurotensin into the vta produces cpp and enhances da release in the nucleus accumbens (nac), and (b) gaba(a) antagonists are self-administered into the anterior vta and injections of gaba(a) antagonists into the anterior vta enhance da release in the nac. |
1999-08-23 |
2023-08-12 |
rat |
| R D Myers, D E Robinso. Tetrahydropapaveroline injected in the ventral tegmental area shifts dopamine efflux differentially in the shell and core of nucleus accumbens in high-ethanol-preferring (HEP) rats. Alcohol (Fayetteville, N.Y.). vol 18. issue 1. 1999-08-17. PMID:10386670. |
further, thp evokes the extracellular efflux of dopamine in the nucleus accumbens (nac), which comprises, in part, the postulated alcohol drinking "circuit" of neurons. |
1999-08-17 |
2023-08-12 |
rat |
| C E Beyer, J D Stekete. Dopamine depletion in the medial prefrontal cortex induces sensitized-like behavioral and neurochemical responses to cocaine. Brain research. vol 833. issue 2. 1999-08-13. PMID:10375688. |
likewise, 6-ohda lesions of the mpfc produced a significant enhancement of cocaine-induced da transmission in the nucleus accumbens (nac) as estimated by in vivo microdialysis. |
1999-08-13 |
2023-08-12 |
Not clear |
| M Sarter, J P Bruno, J Turch. Basal forebrain afferent projections modulating cortical acetylcholine, attention, and implications for neuropsychiatric disorders. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415659. |
studies on the regulation of cortical ach efflux by nucleus accumbens (nac) dopamine (da) demonstrate that increases in cortical ach efflux are attenuated by intra-accumbens administration of d1 and, more potently, d2 receptor antagonists. |
1999-08-10 |
2023-08-12 |
rat |
| C H West, K A Boss-Williams, J M Weis. Motor activation by amphetamine infusion into nucleus accumbens core and shell subregions of rats differentially sensitive to dopaminergic drugs. Behavioural brain research. vol 98. issue 1. 1999-07-28. PMID:10210531. |
in light of the importance of the nucleus accumbens (nac) in amphetamine-induced activity, the present study investigated whether da function in nac differs in swhi and swlo rats. |
1999-07-28 |
2023-08-12 |
rat |
| Y Itzhak, J L Martin, M D Black, S F Al. Effect of the dopaminergic neurotoxin MPTP on cocaine-induced locomotor sensitization. Pharmacology, biochemistry, and behavior. vol 63. issue 1. 1999-07-28. PMID:10340529. |
the blockade of dopamine (da) uptake via the dopamine transporter (dat) in the nucleus accumbens (nac) and striatum by cocaine has a major role in the reinforcing and psychomotor stimulating effects of the drug. |
1999-07-28 |
2023-08-12 |
mouse |
| S ThyagaRajan, S Y Stevens, D L Felte. Region-specific alterations in the concentrations of catecholamines and indoleamines in the brains of young and old F344 rats after L-deprenyl treatment. Brain research bulletin. vol 48. issue 5. 1999-07-28. PMID:10372512. |
the effects of l-deprenyl, a monoamine oxidase-b (mao-b) inhibitor, on the concentrations of norepinephrine (ne), dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), serotonin (5-hydroxytryptamine), and 5-hydroxyindoleacetic acid (5-hiaa) in medial basal hypothalamus (mbh), substantia nigra (sn), striatum (str), and nucleus accumbens (nac) of young (3 month) and old (21 month) male f344 rats were examined after a 7-day wash-out period following 1, 15, or 30 days of deprenyl treatment in young rats and a 9-day wash-out period after a 10-week deprenyl treatment in old rats. |
1999-07-28 |
2023-08-12 |
rat |
| F I Tarazi, E C Tomasini, R J Baldessarin. Postnatal development of dopamine D1-like receptors in rat cortical and striatolimbic brain regions: An autoradiographic study. Developmental neuroscience. vol 21. issue 1. 1999-07-14. PMID:10077701. |
postnatal development of dopamine d1-like (d1/d5) receptors in rat caudate-putamen (cpu), nucleus accumbens (nac), hippocampus, frontal and entorhinal cerebral cortex was assessed between postnatal days (pd) 7-60 by in vitro receptor autoradiography. |
1999-07-14 |
2023-08-12 |
rat |
| U Krügel, H Kittner, P Ille. Adenosine 5'-triphosphate-induced dopamine release in the rat nucleus accumbens in vivo. Neuroscience letters. vol 265. issue 1. 1999-07-14. PMID:10327203. |
microdialysis experiments were used to investigate the influence of locally applied 2-methylthioadenosine 5'-triphosphate (2-mesatp) on extracellular dopamine concentrations in the rat nucleus accumbens (nac). |
1999-07-14 |
2023-08-12 |
rat |
| A Vecchiola, P Collyer, R Figueroa, R Labarca, G Bustos, K Magendz. Differential regulation of mu-opioid receptor mRNA in the nucleus accumbens shell and core accompanying amphetamine behavioral sensitization. Brain research. Molecular brain research. vol 69. issue 1. 1999-07-12. PMID:10350632. |
to investigate the participation of the opioid system in this phenomenon, we examined the effects of acute and repeated amph administration on mu-opioid receptor (mor) mrna levels in the nucleus accumbens (nac) and striatum (str) of rats, by quantitative non-radioactive in situ hybridization. |
1999-07-12 |
2023-08-12 |
rat |
| W Lu, M E Wol. Repeated amphetamine administration alters AMPA receptor subunit expression in rat nucleus accumbens and medial prefrontal cortex. Synapse (New York, N.Y.). vol 32. issue 2. 1999-06-22. PMID:10231131. |
(1997) synapse 26:269-280] that repeated amphetamine administration alters ampa receptor subunit mrna levels in rat nucleus accumbens (nac) and medial prefrontal cortex (pfc). |
1999-06-22 |
2023-08-12 |
rat |
| F I Tarazi, E C Tomasini, R J Baldessarin. Postnatal development of dopamine and serotonin transporters in rat caudate-putamen and nucleus accumbens septi. Neuroscience letters. vol 254. issue 1. 1999-06-07. PMID:9780082. |
density of dopamine transporter (dat) and serotonin transporter (5-htt) membrane proteins in the caudate-putamen (cpu) and nucleus accumbens (nac) of rat brain was assessed at seven ages at postnatal days (pd) 7-60, by in vitro quantitative autoradiography. |
1999-06-07 |
2023-08-12 |
rat |
| M F Roitman, T A Patterson, R R Sakai, I L Bernstein, D P Figlewic. Sodium depletion and aldosterone decrease dopamine transporter activity in nucleus accumbens but not striatum. The American journal of physiology. vol 276. issue 5. 1999-06-03. PMID:10233025. |
motivated behaviors, including sodium (na) appetite, are correlated with increased dopamine (da) transmission in the nucleus accumbens (nac). |
1999-06-03 |
2023-08-12 |
rat |
| F S Hall, L S Wilkinson, T Humby, T W Robbin. Maternal deprivation of neonatal rats produces enduring changes in dopamine function. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188636. |
however, in the present study it is reported that in vivo microdialysis of the nucleus accumbens (nac) revealed enhanced release of dopamine (da) in response to both d-amphetamine and high k+ perfusate in maternally deprived subjects. |
1999-06-01 |
2023-08-12 |
human |
| B A Horger, C A Iyasere, M T Berhow, C J Messer, E J Nestler, J R Taylo. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 10. 1999-06-01. PMID:10234039. |
in experiment 1, bdnf was infused into the nucleus accumbens (nac) or ventral tegmental area over 2 weeks via chronically implanted minipumps (1-2.5 microgram/d), and the psychomotor stimulant effects of cocaine (5-15 mg/kg, i.p.) |
1999-06-01 |
2023-08-12 |
mouse |
| J R Taylor, B A Horge. Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitization. Psychopharmacology. vol 142. issue 1. 1999-05-26. PMID:10102780. |
on 2 test days, 8-10 days later, subjects were given amphetamine (6 microg/0.5 microl) or saline infusions into the nucleus accumbens (nac) and responding for cr was measured using the "acquisition of a new response" paradigm. |
1999-05-26 |
2023-08-12 |
human |