| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P V Rada, G P Mark, B G Hoebe. Dopamine release in the nucleus accumbens by hypothalamic stimulation-escape behavior. Brain research. vol 782. issue 1-2. 1998-05-14. PMID:9519267. |
it is known that lateral hypothalamic stimulation or self-stimulation can release dopamine in the nucleus accumbens (nac). |
1998-05-14 |
2023-08-12 |
rat |
| P J Wellman, D K Miller, C L Livermore, T A Green, L R McMahon, J R Natio. Effects of (-)-ephedrine on locomotion, feeding, and nucleus accumbens dopamine in rats. Psychopharmacology. vol 135. issue 2. 1998-05-08. PMID:9497018. |
the intent of the present study was to determine the effects of systemic injections of the sympathomimetic agent ephedrine (eph) on extracellular dopamine (da) levels within the rat nucleus accumbens (nac) and to compare these effects with those of eph on locomotion and on feeding. |
1998-05-08 |
2023-08-12 |
rat |
| D L Willins, H Y Meltze. Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens. Brain research. vol 781. issue 1-2. 1998-04-29. PMID:9507167. |
in vivo microdialysis was used to compare the effects of serotonergic drugs on morphine- and cocaine-induced increases in extracellular dopamine (da) concentrations in the rat nucleus accumbens (nac). |
1998-04-29 |
2023-08-12 |
rat |
| J M Mathé, G G Nomikos, B Schilström, T H Svensso. Non-NMDA excitatory amino acid receptors in the ventral tegmental area mediate systemic dizocilpine (MK-801) induced hyperlocomotion and dopamine release in the nucleus accumbens. Journal of neuroscience research. vol 51. issue 5. 1998-04-24. PMID:9512002. |
this study investigated the putative role of non-nmda excitatory amino acid (eaa) receptors in the ventral tegmental area (vta) for the increase in dopamine (da) release in the nucleus accumbens (nac) and behavioral stimulation induced by systemically administered dizocilpine (mk-801). |
1998-04-24 |
2023-08-12 |
rat |
| G Zernig, H C Fibige. Acute and prolonged effects of clocinnamox and methoclocinnamox on nucleus accumbens dopamine overflow. Psychopharmacology. vol 135. issue 1. 1998-04-22. PMID:9489929. |
in vivo microdialysis was employed to determine if these effects are paralleled in basal and opioid-stimulated dopamine (da) overflow in the rat nucleus accumbens (nac). |
1998-04-22 |
2023-08-12 |
rat |
| J Y Chang, P H Janak, D J Woodwar. Comparison of mesocorticolimbic neuronal responses during cocaine and heroin self-administration in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 8. 1998-04-20. PMID:9526026. |
to compare neuronal activity within the mesocorticolimbic circuit during the self-administration of cocaine and heroin, multiple-channel single-unit recordings of spike activity within the rat medial prefrontal cortex (mpfc) and nucleus accumbens (nac) were obtained during the consecutive self-administration of cocaine and heroin within the same session. |
1998-04-20 |
2023-08-12 |
rat |
| M A Parada, M Puig de Parada, L Hernandez, E Murzi, F Garci. A practical method for simultaneous multiple intracerebral implantations for microdialysis in rats. Brain research. Brain research protocols. vol 2. issue 2. 1998-04-03. PMID:9473636. |
the design may vary according to the type of elements to be implanted and the coordinates required for each particular experiment, but here it is illustrated describing the assembly of a particular jig for the simultaneous implantation of guide shafts for ulterior microdialysis in the prefrontal cortex (pfc), nucleus accumbens (nac) and striatum (str). |
1998-04-03 |
2023-08-12 |
rat |
| B E Hildebrand, G G Nomikos, P Hertel, B Schilström, T H Svensso. Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Brain research. vol 779. issue 1-2. 1998-04-02. PMID:9473676. |
withdrawal from chronic treatment with various types of addictive drugs, including amphetamine, cocaine, ethanol and morphine is associated with a decrease in dopaminergic output in the nucleus accumbens (nac), whereas the effects of withdrawal from these drugs on dopaminergic output in the medial prefrontal cortex (pfc), as yet, remain largely unknown. |
1998-04-02 |
2023-08-12 |
rat |
| D W Self, L M Genova, B T Hope, W J Barnhart, J J Spencer, E J Nestle. Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 5. 1998-03-04. PMID:9465009. |
camp-dependent protein kinase (pka) in the nucleus accumbens (nac) has been implicated in cocaine addiction because (1) cocaine reinforcement is mediated by dopamine receptors that modulate camp formation, and (2) repeated exposure to cocaine upregulates the camp system in nac neurons. |
1998-03-04 |
2023-08-12 |
human |
| H C Hung, E H Le. MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways. Free radical biology & medicine. vol 24. issue 1. 1998-03-02. PMID:9436616. |
results revealed that mptp increased lipid peroxidation in the striatum (st) and decreased glutathione concentration in the substantia nigra (sn) without markedly affecting these measures in the nucleus accumbens (nac) and ventral tegmental area (vta). |
1998-03-02 |
2023-08-12 |
mouse |
| H Takahashi, Y Takada, N Nagai, T Urano, A Takad. Effects of nicotine and footshock stress on dopamine release in the striatum and nucleus accumbens. Brain research bulletin. vol 45. issue 2. 1998-02-26. PMID:9443833. |
we have used a microdialysis technique to analyze the effects of nicotine administration on the release of dopamine in the striatum and the nucleus accumbens (nac) in rats under footshock stress. |
1998-02-26 |
2023-08-12 |
rat |
| H Ozer, A C Ekinci, M S Star. Dopamine D1- and D2-dependent catalepsy in the rat requires functional NMDA receptors in the corpus striatum, nucleus accumbens and substantia nigra pars reticulata. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449412. |
mk-801, 0.2 mg/kg i.p., strongly opposed the cataleptogenic actions of sch 23390 and raclopride administered systemically (1 and 3 mg/kg i.p., respectively), or directly into the corpus striatum (cs) or nucleus accumbens (nac; 1 and 10 microg, respectively). |
1998-02-24 |
2023-08-12 |
rat |
| I Weiner, J Feldo. The switching model of latent inhibition: an update of neural substrates. Behavioural brain research. vol 88. issue 1. 1998-02-04. PMID:9401704. |
on the basis of these findings, the switching model of li proposed that li depends on the subicular input to the nucleus accumbens (nac). |
1998-02-04 |
2023-08-12 |
Not clear |
| G Tanda, F E Pontieri, R Frau, G Di Chiar. Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine. The European journal of neuroscience. vol 9. issue 10. 1998-02-04. PMID:9421168. |
to this end, changes of extracellular da and na in the pfcx and of extracellular da in the nucleus accumbens (nac) were measured following the administration of amphetamine and cocaine, which are known to bind to both da and na carriers, or gbr 12909, a selective da carrier blocker. |
1998-02-04 |
2023-08-12 |
rat |
| R J Moore, S L Vinsant, M A Nader, L J Porrino, D P Friedma. Effect of cocaine self-administration on striatal dopamine D1 receptors in rhesus monkeys. Synapse (New York, N.Y.). vol 28. issue 1. 1998-01-20. PMID:9414012. |
because the release of dopamine in the nucleus accumbens (nac) has been implicated in mediating the reinforcing effects of cocaine, changes in dopamine function can have profound effects on drug-seeking and drug-taking behavior. |
1998-01-20 |
2023-08-12 |
monkey |
| M Yoshida, H Yokoo, K Nakahara, M Tomita, N Hamada, M Ishikawa, J Hatakeyama, M Tanaka, I Nagats. Local muscimol disinhibits mesolimbic dopaminergic activity as examined by brain microdialysis and Fos immunohistochemistry. Brain research. vol 767. issue 2. 1998-01-15. PMID:9367268. |
infusion of muscimol (5 x 10[-5] m, 60 min) into the nucleus accumbens (nac) through a dialysis membrane caused a significant increase in extracellular dopamine (da) and its metabolite, 3,4-dihydroxyphenylacetic acid (dopac). |
1998-01-15 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, K Chergui, P Grillner, T H Svensso. Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 3. 1998-01-08. PMID:9272482. |
in the present study, expression of the immediate early gene protein products fos and jun-b within the dorsolateral striatum, the core and shell of the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the ventrolateral orbital cortex was examined. |
1998-01-08 |
2023-08-12 |
rat |
| H Mann, B Ladenheim, H Hirata, T H Moran, J L Cade. Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice. Brain research. vol 769. issue 2. 1997-12-23. PMID:9374204. |
meth caused significant dose-dependent decreases of dopamine (da) and da transporters (dat) in the striatum and the nucleus accumbens (nac) of both wild-type and knockout mice. |
1997-12-23 |
2023-08-12 |
mouse |
| B H Guevara, I S Hoffmann, L X Cubedd. Ventral and dorsal striatal cholinergic neurons have different sensitivities to kainic acid. Neurochemistry international. vol 31. issue 5. 1997-12-22. PMID:9364458. |
direct stereotaxic injections of high-dose ka (4 micrograms/2 microliters) into specific brain regions, reduced cat in caudate putamen (cp) by 91 +/- 1%, in nucleus accumbens (nac) by 71 +/- 6%, but cat in the olfactory tubercle (ot) was not affected by ka. |
1997-12-22 |
2023-08-12 |
rat |
| B Bontempi, F R Shar. Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334431. |
to characterize how systemic morphine induces fos protein in dorsomedial striatum and nucleus accumbens (nac), we examined the role of receptors in striatum, substantia nigra (sn), and ventral tegmental area (vta). |
1997-11-20 |
2023-08-12 |
rat |