| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher W Tschumi, Michael J Beckstea. Neurotensin speeds inhibition of dopamine neurons through temporal modulation of GABA Neuropharmacology. vol 131. 2018-11-19. PMID:29307543. |
neurotensin (nt) is a neuropeptide which acutely modulates midbrain dopamine neuron excitability through multiple mechanisms, one of which is a decrease of gaba-mediated inhibition. |
2018-11-19 |
2023-08-13 |
mouse |
| Qiaofeng Liu, Yanxia Li, Yang Liu, Yanshuang Zhao, Xuemei Li, Yiping Zhang, Chenyi Wang, Wenli Huang, Xin Wan. A dopamine D1 receptor agonist improved learning and memory in morphine-treated rats. Neurological research. vol 40. issue 12. 2018-11-16. PMID:30222083. |
the objective of this article is to study the role of the dopamine (da) d1 receptor in the midbrain periaqueductal grey (pag) on learning and memory in morphine-addicted rats. |
2018-11-16 |
2023-08-13 |
rat |
| Sarah Fischbach-Weiss, Rebecca M Reese, Patricia H Jana. Inhibiting Mesolimbic Dopamine Neurons Reduces the Initiation and Maintenance of Instrumental Responding. Neuroscience. vol 372. 2018-11-13. PMID:29248527. |
here we used optogenetic inhibition of midbrain th+ neurons to probe the role of dopamine neuron activity during instrumental responding for reward by varying the time epoch of neural inhibition relative to the time of response initiation. |
2018-11-13 |
2023-08-13 |
mouse |
| Sarah Fischbach-Weiss, Rebecca M Reese, Patricia H Jana. Inhibiting Mesolimbic Dopamine Neurons Reduces the Initiation and Maintenance of Instrumental Responding. Neuroscience. vol 372. 2018-11-13. PMID:29248527. |
we conclude that midbrain dopamine signaling promotes initiation of instrumental responding and maintains motivation to continue ongoing bouts of effortful responses. |
2018-11-13 |
2023-08-13 |
mouse |
| Xinglong Gu, Wei L. Genetic deletion of NMDA receptors suppresses GABAergic synaptic transmission in two distinct types of central neurons. Neuroscience letters. vol 668. 2018-11-09. PMID:29355693. |
here we report that in both cortical pyramidal neurons and midbrain dopamine neurons in ventral tegmental area (vta), genetic deletion of the glun1 subunit, which is required for assembly of functional nmdars, leads to a strong reduction of gabaergic synaptic transmission. |
2018-11-09 |
2023-08-13 |
Not clear |
| Parisa Farzanehfa. Comparative review of adult midbrain and striatum neurogenesis with classical neurogenesis. Neuroscience research. vol 134. 2018-11-01. PMID:29339103. |
parkinson's disease (pd) motor symptoms are caused by loss of dopamine (da) neurons in the substantia nigra pars compacta (snc) of the midbrain. |
2018-11-01 |
2023-08-13 |
Not clear |
| Zsolt Turi, Matthias Mittner, Walter Paulus, Andrea Anta. Placebo Intervention Enhances Reward Learning in Healthy Individuals. Scientific reports. vol 7. 2018-10-29. PMID:28112207. |
according to the placebo-reward hypothesis, placebo is a reward-anticipation process that increases midbrain dopamine (da) levels. |
2018-10-29 |
2023-08-13 |
human |
| Giorgio Rizzi, Kelly R Ta. Dopamine and Acetylcholine, a Circuit Point of View in Parkinson's Disease. Frontiers in neural circuits. vol 11. 2018-09-27. PMID:29311846. |
this review covers some of the recent developments in the field of basal ganglia (bg) function in physiology and pathology, with a particular focus on the two main neuromodulatory systems known to be severely affected in pd, highlighting some of the remaining open question from three main stand points: - heterogeneity of midbrain dopamine neurons. |
2018-09-27 |
2023-08-13 |
Not clear |
| Mohammad Reza Sarukhani, Hashem Haghdoost-Yazdi, Gilda Khandan-Chelarc. Changes in the Serum Urate Level Can Predict the Development of Parkinsonism in the 6-Hydroxydopamine Animal Model. Neurochemical research. vol 43. issue 5. 2018-09-27. PMID:29616443. |
the immunohistofluorescence and biochemical analyses showed that the serum ua level was also correlated with the death of tyrosine hydroxylase (th)-positive neurons in the substantia nigra pars compacta (snc), reduced level of striatal dopamine, and severity of oxidative stress in the midbrain. |
2018-09-27 |
2023-08-13 |
rat |
| Jia Li, Tian Yu, Fu Shi, Yu Zhang, Zikun Duan, Bao Fu, Yi Zhan. Involvement of Ventral Periaqueductal Gray Dopaminergic Neurons in Propofol Anesthesia. Neurochemical research. vol 43. issue 4. 2018-09-24. PMID:29417470. |
whether dopamine (da) neurons in midbrain ventral periaqueductal gray (vpag) are involved in general anesthesia and how general anesthetics affect these neurons remain sparsely documented. |
2018-09-24 |
2023-08-13 |
rat |
| Chun Huang, Fengqin Lin, Guoqing Wang, Disheng Lu, Qin Wu, Jie Liu, Jingshan Shi, Feng Zhan. Tetrahydroxystilbene Glucoside Produces Neuroprotection against 6-OHDA-Induced Dopamine Neurotoxicity. Oxidative medicine and cellular longevity. vol 2018. 2018-09-18. PMID:29576855. |
parkinson's disease (pd) was one of the most common neurodegenerative diseases with a slow and progressive loss of dopamine (da) neurons in the midbrain substantia nigra (sn). |
2018-09-18 |
2023-08-13 |
Not clear |
| Ana C Dutra-Tavares, Juliana O Silva, André L Nunes-Freitas, Vinícius M S Guimarães, Ulisses C Araújo, Ellen P S Conceição, Egberto G Moura, Patrícia C Lisboa, Cláudio C Filgueiras, Alex C Manhães, Yael Abreu-Villaça, Anderson Ribeiro-Carvalh. Maternal undernutrition during lactation alters nicotine reward and DOPAC/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nAChRs upregulation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 65. 2018-09-05. PMID:29054611. |
the goal of this study was to investigate the effects of undernutrition during lactation on the nicotine susceptibility indexed via conditioned place preference (cpp), on dopamine content and turnover and on nicotine-induced nicotinic cholinergic receptor (nachr) upregulation in the cerebral cortex, midbrain and hippocampus of adolescent mice. |
2018-09-05 |
2023-08-13 |
mouse |
| Susanne Nichterwitz, Geng Chen, Julio Aguila Benitez, Marlene Yilmaz, Helena Storvall, Ming Cao, Rickard Sandberg, Qiaolin Deng, Eva Hedlun. Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling. Nature communications. vol 7. 2018-08-29. PMID:27387371. |
importantly, we demonstrate that lcm-seq can provide biological insight on highly similar neuronal populations, including motor neurons isolated from different levels of the mouse spinal cord, as well as human midbrain dopamine neurons of the substantia nigra compacta and the ventral tegmental area. |
2018-08-29 |
2023-08-13 |
mouse |
| Chun Yun Chang, Matthew Gardner, Maria Gonzalez Di Tillio, Geoffrey Schoenbau. Optogenetic Blockade of Dopamine Transients Prevents Learning Induced by Changes in Reward Features. Current biology : CB. vol 27. issue 22. 2018-08-06. PMID:29103933. |
here, we used optogenetic and transgenic approaches to prevent transient changes in midbrain dopamine neuron activity during the critical error-signaling period of two unblocking tasks. |
2018-08-06 |
2023-08-13 |
Not clear |
| Armin Lak, Kensaku Nomoto, Mehdi Keramati, Masamichi Sakagami, Adam Kepec. Midbrain Dopamine Neurons Signal Belief in Choice Accuracy during a Perceptual Decision. Current biology : CB. vol 27. issue 6. 2018-08-01. PMID:28285994. |
midbrain dopamine neurons signal belief in choice accuracy during a perceptual decision. |
2018-08-01 |
2023-08-13 |
monkey |
| Armin Lak, Kensaku Nomoto, Mehdi Keramati, Masamichi Sakagami, Adam Kepec. Midbrain Dopamine Neurons Signal Belief in Choice Accuracy during a Perceptual Decision. Current biology : CB. vol 27. issue 6. 2018-08-01. PMID:28285994. |
in several reinforcement learning contexts, such as pavlovian conditioning and decisions guided by reward history, this rpe signal is provided by midbrain dopamine neurons. |
2018-08-01 |
2023-08-13 |
monkey |
| Ryan M Grippo, Aarti M Purohit, Qi Zhang, Larry S Zweifel, Ali D Güle. Direct Midbrain Dopamine Input to the Suprachiasmatic Nucleus Accelerates Circadian Entrainment. Current biology : CB. vol 27. issue 16. 2018-07-20. PMID:28781050. |
direct midbrain dopamine input to the suprachiasmatic nucleus accelerates circadian entrainment. |
2018-07-20 |
2023-08-13 |
Not clear |
| Jing Ma, Cui Huang, Kun Ma, Yan-Ping Wu, Bai-Xiang Li, Yan Su. Effect of Wnt1 and Wnt5a on the development of dopaminergic neurons, and toxicity induced by combined exposure to paraquat and maneb during gestation and lactation. Molecular medicine reports. vol 16. issue 6. 2018-07-20. PMID:29152652. |
dopamine content in the striatum was examined by high performance liquid chromatography with a fluorescence detector and mrna and protein expression of wnt1, wnt5a, nuclear receptor related factor 1 (nurr1) and tyrosine hydroxylase (th) in the midbrain was examined by reverse transcription‑quantitative polymerase chain reaction and western blotting. |
2018-07-20 |
2023-08-13 |
rat |
| Young-Cho Kim, Sang-Woo Han, Stephanie L Alberico, Rafael N Ruggiero, Benjamin De Corte, Kuan-Hua Chen, Nandakumar S Narayana. Optogenetic Stimulation of Frontal D1 Neurons Compensates for Impaired Temporal Control of Action in Dopamine-Depleted Mice. Current biology : CB. vol 27. issue 1. 2018-07-16. PMID:27989675. |
here, we investigated whether these neurons can compensate for behavioral deficits resulting from midbrain dopamine dysfunction. |
2018-07-16 |
2023-08-13 |
mouse |
| Jaakko Kopra, Marian Villarta-Aguilera, Mari Savolainen, Samo Weingerl, Timo T Myöhänen, Saara Rannanpää, Michael F Salvatore, Jaan-Olle Andressoo, T Petteri Pieppone. Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine. Neuropharmacology. vol 128. 2018-07-13. PMID:29031851. |
glial cell line-derived neurotrophic factor (gdnf) is an important regulator of midbrain dopamine neurons, and may play a mechanistic role in addiction-related behaviors. |
2018-07-13 |
2023-08-13 |
mouse |