| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Torben Ott, Andreas Niede. Dopamine D2 Receptors Enhance Population Dynamics in Primate Prefrontal Working Memory Circuits. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 9. 2018-06-19. PMID:27591146. |
the neuromodulator dopamine, which is released by midbrain neurons projecting into the frontal lobe, influences pfc neurons and networks via the dopamine d1 (d1r) and the d2 receptor (d2r) families. |
2018-06-19 |
2023-08-13 |
monkey |
| Meghan Flanigan, Hossein Aleyasin, Aki Takahashi, Sam A Golden, Scott J Russ. An emerging role for the lateral habenula in aggressive behavior. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28499809. |
the lateral habenula (lhb) has recently been identified as a major node of the classical reward circuitry and inhibits the release of dopamine from the midbrain to signal negative valence. |
2018-06-18 |
2023-08-13 |
Not clear |
| Martin Metzger, Debora Bueno, Leandro B Lim. The lateral habenula and the serotonergic system. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28528079. |
so far, the vast majority of research involving the lhb has focused on its role in regulating midbrain dopamine release. |
2018-06-18 |
2023-08-13 |
Not clear |
| Adam L Orr, Florentine U Rutaganira, Daniel de Roulet, Eric J Huang, Nicholas T Hertz, Kevan M Shokat, Ken Nakamur. Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochemistry international. vol 109. 2018-06-13. PMID:28434973. |
however, there was no degeneration of midbrain dopamine neurons lacking pink1, which precluded an assessment of neuroprotection and raised questions about the robustness of the pink1 ko rat model of pd. |
2018-06-13 |
2023-08-13 |
rat |
| Brian Lau, Tiago Monteiro, Joseph J Pato. The many worlds hypothesis of dopamine prediction error: implications of a parallel circuit architecture in the basal ganglia. Current opinion in neurobiology. vol 46. 2018-06-11. PMID:28985550. |
we focus on one important component of basal ganglia circuitry, midbrain dopamine neurons, drawing attention to data that has been cast as supporting or departing from the rl framework that has inspired experiments in basal ganglia research over the past two decades. |
2018-06-11 |
2023-08-13 |
Not clear |
| Xiantong Yu, XiaoXiao He, Taiqun Yang, Litao Zhao, Qichen Chen, Sanjun Zhang, Jinquan Chen, Jianhua X. Sensitive determination of dopamine levels via surface-enhanced Raman scattering of Ag nanoparticle dimers. International journal of nanomedicine. vol 13. 2018-06-11. PMID:29713165. |
dopamine (da) is an important neurotransmitter in the hypothalamus and pituitary gland, which can produce a direct influence on mammals' emotions in midbrain. |
2018-06-11 |
2023-08-13 |
Not clear |
| Hiroshi Ito, Hiroshi Kawaguchi, Fumitoshi Kodaka, Hiroyuki Takuwa, Yoko Ikoma, Hitoshi Shimada, Yasuyuki Kimura, Chie Seki, Hitoshi Kubo, Shiro Ishii, Harumasa Takano, Tetsuya Suhar. Normative data of dopaminergic neurotransmission functions in substantia nigra measured with MRI and PET: Neuromelanin, dopamine synthesis, dopamine transporters, and dopamine D NeuroImage. vol 158. 2018-06-01. PMID:28655632. |
in the present study, the normative data of dopaminergic neurotransmission functions in the midbrain, consisting of neuromelanin, dopamine synthesis, dopamine transporters and dopamine d |
2018-06-01 |
2023-08-13 |
Not clear |
| Anupama Dey, Parisa Farzanehfar, Elena V Gazina, Tim D Auman. Electrophysiological and gene expression characterization of the ontogeny of nestin-expressing cells in the adult mouse midbrain. Stem cell research. vol 23. 2018-05-30. PMID:28743044. |
the birth of new neurons, or neurogenesis, in the adult midbrain is important for progressing dopamine cell-replacement therapies for parkinson's disease. |
2018-05-30 |
2023-08-13 |
mouse |
| Noviana Wulansari, Eun-Hee Kim, Yanuar Alan Sulistio, Yong-Hee Rhee, Jae-Jin Song, Sang-Hun Le. Vitamin C-Induced Epigenetic Modifications in Donor NSCs Establish Midbrain Marker Expressions Critical for Cell-Based Therapy in Parkinson's Disease. Stem cell reports. vol 9. issue 4. 2018-05-24. PMID:28943252. |
here, we show that treatment of vitamin c (vc) enhances generation of authentic midbrain-type dopamine (mda) neurons with improved survival and functions from ventral midbrain (vm)-derived nscs. |
2018-05-24 |
2023-08-13 |
rat |
| Melissa J Sharpe, Hannah M Batchelor, Geoffrey Schoenbau. Preconditioned cues have no value. eLife. vol 6. 2018-05-22. PMID:28925358. |
sensory preconditioning has been used to implicate midbrain dopamine in model-based learning, contradicting the view that dopamine transients reflect model-free value. |
2018-05-22 |
2023-08-13 |
rat |
| Yizhou Ye, Surjeet Mastwal, Vania Yu Cao, Ming Ren, Qing Liu, Wenyu Zhang, Abdel G Elkahloun, Kuan Hong Wan. Dopamine is Required for Activity-Dependent Amplification of Arc mRNA in Developing Postnatal Frontal Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 7. 2018-05-21. PMID:27365296. |
furthermore, visual stimuli-driven amplification of arc mrna is also dependent on d1r activation and dopamine neurons located in the ventral midbrain. |
2018-05-21 |
2023-08-13 |
mouse |
| Nicole Gennet, Claudia Tamburini, Xinsheng Nan, Meng L. FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons. Scientific reports. vol 6. 2018-05-16. PMID:27580818. |
folr1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons. |
2018-05-16 |
2023-08-13 |
mouse |
| Jonathan C Niclis, Carlos W Gantner, Cameron P J Hunt, Jessica A Kauhausen, Jennifer C Durnall, John M Haynes, Colin W Pouton, Clare L Parish, Lachlan H Thompso. A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells. Stem cell reports. vol 9. issue 3. 2018-05-14. PMID:28867345. |
here, we have used a human pitx3-egfp embryonic stem cell line to characterize the connectivity of stem cell-derived midbrain dopamine neurons in the dopamine-depleted host brain with an unprecedented level of specificity. |
2018-05-14 |
2023-08-13 |
human |
| Haidy E Michel, Mariane G Tadros, Ahmed Esmat, Amani E Khalifa, Ahmed M Abdel-Tawa. Tetramethylpyrazine Ameliorates Rotenone-Induced Parkinson's Disease in Rats: Involvement of Its Anti-Inflammatory and Anti-Apoptotic Actions. Molecular neurobiology. vol 54. issue 7. 2018-05-10. PMID:27514753. |
results showed that tmp (20 mg/kg) significantly improved midbrain and striatal th expression and striatal dopamine content as well as the motor deficits, compared to rotenone-treated group. |
2018-05-10 |
2023-08-13 |
rat |
| Panojot Bifsha, Aurelio Balsalobre, Jacques Droui. Specificity of Pitx3-Dependent Gene Regulatory Networks in Subsets of Midbrain Dopamine Neurons. Molecular neurobiology. vol 54. issue 7. 2018-05-10. PMID:27514757. |
specificity of pitx3-dependent gene regulatory networks in subsets of midbrain dopamine neurons. |
2018-05-10 |
2023-08-13 |
human |
| Gael Le Douaron, Laurent Ferrié, Julia E Sepulveda-Diaz, Blandine Séon-Méniel, Rita Raisman-Vozari, Patrick P Michel, Bruno Figadèr. Identification of a Novel 1,4,8-Triazaphenanthrene Derivative as a Neuroprotectant for Dopamine Neurons Vulnerable in Parkinson's Disease. ACS chemical neuroscience. vol 8. issue 6. 2018-05-01. PMID:28140556. |
parkinson's disease (pd) is a chronic degenerative disorder characterized by typical motor symptoms caused by the death of dopamine (da) neurons in the midbrain and ensuing shortage of da in the striatum, at the level of nerve terminals. |
2018-05-01 |
2023-08-13 |
mouse |
| Lorenz Stude. Strategies for bringing stem cell-derived dopamine neurons to the clinic-The NYSTEM trial. Progress in brain research. vol 230. 2018-05-01. PMID:28552229. |
over the last 10 years, there has been significant progress in defining culture conditions to derive bona fide human midbrain dopamine (mda) neurons from human embryonic stem cells or from human-induced pluripotent stem cells, two cell sources referred to as human pluripotent stem cells (hpscs). |
2018-05-01 |
2023-08-13 |
human |
| L Boekhoudt, T J M Roelofs, J W de Jong, A E de Leeuw, M C M Luijendijk, I G Wolterink-Donselaar, G van der Plasse, R A H Ada. Does activation of midbrain dopamine neurons promote or reduce feeding? International journal of obesity (2005). vol 41. issue 7. 2018-04-30. PMID:28321131. |
does activation of midbrain dopamine neurons promote or reduce feeding? |
2018-04-30 |
2023-08-13 |
Not clear |
| Dustin R Wakeman, Benjamin M Hiller, David J Marmion, Christopher W McMahon, Grant T Corbett, Kile P Mangan, Junyi Ma, Lauren E Little, Zhong Xie, Tamara Perez-Rosello, Jaime N Guzman, D James Surmeier, Jeffrey H Kordowe. Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo. Stem cell reports. vol 9. issue 1. 2018-04-30. PMID:28579395. |
to address this obstacle, midbrain dopamine neurons were derived from human induced pluripotent stem cells (ipsc-mda) and cryopreserved in large production lots for biochemical and transplantation studies. |
2018-04-30 |
2023-08-13 |
human |
| Xiaojie Liu, Peng Zhong, Casey Vickstrom, Yan Li, Qing-Song Li. PDE4 Inhibition Restores the Balance Between Excitation and Inhibition in VTA Dopamine Neurons Disrupted by Repeated In Vivo Cocaine Exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 10. 2018-04-24. PMID:28497801. |
repeated cocaine exposure in vivo caused a decrease in inhibitory postsynaptic currents (ipscs) and an increase in the ampar/nmdar ratio in ventral tegmental area (vta) dopamine neurons in midbrain slices ex vivo. |
2018-04-24 |
2023-08-13 |
mouse |