| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Omar Soler-Cedeño, Hannah Alton, Guo-Hua Bi, Emily Linz, Lipin Ji, Alexandros Makriyannis, Zheng-Xiong X. AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-04-10. PMID:38600154. |
however, in optical intracranial self-stimulation (oicss) maintained by optogenetic stimulation of midbrain dopamine neurons in dat-cre mice, both am6527 and rimonabant dose-dependently inhibited dopamine-dependent oicss behavior. |
2024-04-10 |
2024-04-13 |
mouse |
| Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlman. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model. eLife. vol 12. 2024-04-08. PMID:38587883. |
transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a parkinsonism lesion model. |
2024-04-08 |
2024-04-10 |
mouse |
| Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlman. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model. eLife. vol 12. 2024-04-08. PMID:38587883. |
midbrain dopamine (mda) neurons comprise diverse cells with unique innervation targets and functions. |
2024-04-08 |
2024-04-10 |
mouse |
| Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J Young, Gabriella E Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J Magill, Paul D Dodso. Distributional coding of associative learning in discrete populations of midbrain dopamine neurons. Cell reports. vol 43. issue 4. 2024-04-06. PMID:38581677. |
distributional coding of associative learning in discrete populations of midbrain dopamine neurons. |
2024-04-06 |
2024-04-10 |
Not clear |
| Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J Young, Gabriella E Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J Magill, Paul D Dodso. Distributional coding of associative learning in discrete populations of midbrain dopamine neurons. Cell reports. vol 43. issue 4. 2024-04-06. PMID:38581677. |
midbrain dopamine neurons are thought to play key roles in learning by conveying the difference between expected and actual outcomes. |
2024-04-06 |
2024-04-10 |
Not clear |
| Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J Young, Gabriella E Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J Magill, Paul D Dodso. Distributional coding of associative learning in discrete populations of midbrain dopamine neurons. Cell reports. vol 43. issue 4. 2024-04-06. PMID:38581677. |
here, we investigated the organizational logic of dopaminergic signaling by recording and labeling individual midbrain dopamine neurons during associative behavior. |
2024-04-06 |
2024-04-10 |
Not clear |
| Harysh Winster Suresh Babu, Sindduja Muthu Kumar, Harsimrat Kaur, Mahalaxmi Iyer, Balachandar Vellingir. Midbrain organoids for Parkinson's disease (PD) - A powerful tool to understand the disease pathogenesis. Life sciences. 2024-04-05. PMID:38580194. |
in the context of parkinson's disease (pd), recent advancements have been made in the development of midbrain organoids (mbos) models that consider key pathophysiological mechanisms such as alpha-synuclein (α-syn), lewy bodies, dopamine loss, and microglia activation. |
2024-04-05 |
2024-04-10 |
human |
| Alice Petty, Anna Garcia-Hidalgo, Els F Halff, Sridhar Natesan, Dominic J Withers, Elaine E Irvine, Michelle Kokkinou, Lisa A Wells, David R Bonsall, Sac-Pham Tang, Mattia Veronese, Oliver D Howe. Correction: Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study. Molecular imaging and biology. 2024-04-03. PMID:38570447. |
correction: sub-chronic ketamine administration increases dopamine synthesis capacity in the mouse midbrain: a preclinical in vivo pet study. |
2024-04-03 |
2024-04-06 |
mouse |
| Jessica M Phillips, Mohsen Afrasiabi, Niranjan A Kambi, Michelle J Redinbaugh, Summer Steely, Emily R Johnson, Xi Cheng, Maath Fayyad, Sounak Mohanta, Asia Carís, Charles B Mikell, Sima Mofakham, Yuri B Saalman. Primate thalamic nuclei select abstract rules and shape prefrontal dynamics. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559142. |
md, a major recipient of midbrain dopamine input, was first to represent information about behavioral outcomes. |
2024-04-01 |
2024-04-04 |
monkey |
| Zahra Z Farahbakhsh, Katherine M Holleran, Jonathon P Sens, Steve C Fordahl, Madelyn I Mauterer, Alberto J López, Verginia C Cuzon Carlson, Drew D Kiraly, Kathleen A Grant, Sara R Jones, Cody A Sicilian. Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559169. |
synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking. |
2024-04-01 |
2024-04-04 |
Not clear |
| Vasileios Glykos, Shigeyoshi Fujisaw. Memory-specific encoding activities of the ventral tegmental area dopamine and GABA neurons. eLife. vol 12. 2024-03-21. PMID:38512339. |
although the midbrain dopamine (da) system plays a crucial role in higher cognitive functions, including updating and maintaining short-term memory, the encoding properties of the somatic spiking activity of ventral tegmental area (vta) da neurons for short-term memory computations have not yet been identified. |
2024-03-21 |
2024-03-23 |
mouse |
| Patrick R Melugin, Suzanne O Nolan, Evelyn Kandov, Carson F Ferrara, Zahra Z Farahbakhsh, Cody A Sicilian. Medial prefrontal dopamine dynamics reflect allocation of selective attention. bioRxiv : the preprint server for biology. 2024-03-18. PMID:38496533. |
the mesocortical dopamine system is comprised of midbrain dopamine neurons that predominantly innervate the medial prefrontal cortex (mpfc) and exert a powerful neuromodulatory influence over this region |
2024-03-18 |
2024-03-20 |
Not clear |
| Yixin Fu, Wenfu Li, Yunlin Mai, Junhao Guan, Ruxuan Ding, Jiawei Hou, Bingqing Chen, Guoxin Cao, Shizhu Sun, Ying Tang, Rao F. Association between RMTg Neuropeptide Genes and Negative Effect during Alcohol Withdrawal in Mice. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38474180. |
the rostromedial tegmental nucleus (rmtg), which inhibits midbrain dopamine neurons and signals aversion, has been shown to increase ethanol consumption and negative emotional states during abstinence. |
2024-03-13 |
2024-03-15 |
mouse |
| Kelley E Gunther, Xiaoxue Fu, Leigha A MacNeill, Morgan Jones, Briana Ermanni, Koraly Pérez-Edga. Now it's your turn!: Eye blink rate in a Jenga task modulated by interaction of task wait times, effortful control, and internalizing behaviors. PloS one. vol 19. issue 3. 2024-03-08. PMID:38457390. |
eye blink rate is a non-invasive proxy metric of midbrain dopamine activity. |
2024-03-08 |
2024-03-11 |
Not clear |
| Kelley E Gunther, Xiaoxue Fu, Leigha A MacNeill, Morgan Jones, Briana Ermanni, Koraly Pérez-Edga. Now it's your turn!: Eye blink rate in a Jenga task modulated by interaction of task wait times, effortful control, and internalizing behaviors. PloS one. vol 19. issue 3. 2024-03-08. PMID:38457390. |
these findings index task-related changes in midbrain dopamine activity in relation to naturalistic task demands, and that these changes may vary as a function of individual differences in effortful control and internalizing behaviors. |
2024-03-08 |
2024-03-11 |
Not clear |
| Domenic H Cerri, Daniel L Albaugh, Lindsay R Walton, Brittany Katz, Tzu-Wen Wang, Tzu-Hao Harry Chao, Weiting Zhang, Randal J Nonneman, Jing Jiang, Sung-Ho Lee, Amit Etkin, Catherine N Hall, Garret D Stuber, Yen-Yu Ian Shi. Distinct neurochemical influences on fMRI response polarity in the striatum. Nature communications. vol 15. issue 1. 2024-03-01. PMID:38429266. |
in parallel, midbrain dopaminergic neuron optogenetic modulation, coupled with electrochemical measurements, establishes a link between striatal vasodilation and dopamine release. |
2024-03-01 |
2024-03-04 |
rat |
| Mohamed A Eldeeb, Andrew N Bayne, Armaan Fallahi, Thomas Goiran, Emma J MacDougall, Andrea Soumbasis, Cornelia E Zorca, Jace-Jones Tabah, Rhalena A Thomas, Nathan Karpilovsky, Meghna Mathur, Thomas M Durcan, Jean-François Trempe, Edward A Fo. Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 10. 2024-02-28. PMID:38416681. |
herein, we demonstrate that mitochondrial stress induces the formation of a pink1-tom-tim23 supercomplex in human cultured cell lines, dopamine neurons, and midbrain organoids. |
2024-02-28 |
2024-03-02 |
human |
| Nan Huang, Jian Cui, Guangyuan Fan, Tao Pan, Kunxiu Han, Kailiang Xu, Changyou Jiang, Xing Liu, Feifei Wang, Lan Ma, Qiumin L. Transcriptomic effects of paternal cocaine-seeking on the reward circuitry of male offspring. Translational psychiatry. vol 14. issue 1. 2024-02-28. PMID:38409093. |
consistently, these nuclei showed decreased dopamine levels, elevated neuronal activation, and elevated between-nuclei correlations, indicating dopamine-centered rewiring of the midbrain circuit in the csa offspring. |
2024-02-28 |
2024-03-01 |
rat |
| Jinyoung Jang, Shin Hye Kim, Ki Bum Um, Hyun Jin Kim, Myoung Kyu Par. Somatodendritic organization of pacemaker activity in midbrain dopamine neurons. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 28. issue 2. 2024-02-28. PMID:38414399. |
somatodendritic organization of pacemaker activity in midbrain dopamine neurons. |
2024-02-28 |
2024-03-01 |
Not clear |
| Jinyoung Jang, Shin Hye Kim, Ki Bum Um, Hyun Jin Kim, Myoung Kyu Par. Somatodendritic organization of pacemaker activity in midbrain dopamine neurons. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 28. issue 2. 2024-02-28. PMID:38414399. |
the slow and regular pacemaking activity of midbrain dopamine (da) neurons requires proper spatial organization of the excitable elements between the soma and dendritic compartments, but the somatodendritic organization is not clear. |
2024-02-28 |
2024-03-01 |
Not clear |