| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fares J P Sayegh, Lionel Mouledous, Catherine Macri, Juliana Pi Macedo, Camille Lejards, Claire Rampon, Laure Verret, Lionel Daha. Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning. Nature communications. vol 15. issue 1. 2024-05-21. PMID:38773091. |
thus, activation of midbrain dopamine can operate as a teaching signal that triggers neohebbian ltp and promotes supervised learning. |
2024-05-21 |
2024-05-27 |
mouse |
| Megan Caldwell, Josue Criollo Mendoza, Xin Yan Zhu Jiang, Colin Alarcon, Vanessa Ayo-Jibunoh, Shelby Louis, Daniel Maronna, Rania Darwish, Jaquelyn Tomaio, Susana Mingote, Leora Yetnikof. Reorganization of dopamine circuitry in the anterior corpus callosum between early adolescence and adulthood in the mouse. The European journal of neuroscience. vol 59. issue 10. 2024-05-21. PMID:38720367. |
we recently demonstrated in the adult mouse brain that axon terminals arising from midbrain dopamine neurons innervate the anterior corpus callosum and that oligodendrocyte lineage cells in this white matter tract express dopamine receptor transcripts. |
2024-05-21 |
2024-05-27 |
mouse |
| Dominik Szabó, Vedran Franke, Simona Bianco, Mykhailo Y Batiuk, Eleanor J Paul, Alexander Kukalev, Ulrich G Pfisterer, Ibai Irastorza-Azcarate, Andrea M Chiariello, Samuel Demharter, Luna Zea-Redondo, Jose P Lopez-Atalaya, Mario Nicodemi, Altuna Akalin, Konstantin Khodosevich, Mark A Ungless, Warren Winick-Ng, Ana Pomb. A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766140. |
midbrain dopamine neurons (dns) respond to a first exposure to addictive drugs and play key roles in chronic drug usage |
2024-05-20 |
2024-05-27 |
Not clear |
| Dominik Szabó, Vedran Franke, Simona Bianco, Mykhailo Y Batiuk, Eleanor J Paul, Alexander Kukalev, Ulrich G Pfisterer, Ibai Irastorza-Azcarate, Andrea M Chiariello, Samuel Demharter, Luna Zea-Redondo, Jose P Lopez-Atalaya, Mario Nicodemi, Altuna Akalin, Konstantin Khodosevich, Mark A Ungless, Warren Winick-Ng, Ana Pomb. A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766140. |
a single dose of cocaine rewires the 3d genome structure of midbrain dopamine neurons. |
2024-05-20 |
2024-05-27 |
Not clear |
| Kenta Abe, Yuki Kambe, Kei Majima, Zijing Hu, Makoto Ohtake, Ali Momennezhad, Hideki Izumi, Takuma Tanaka, Ashley Matunis, Emma Stacy, Takahide Itokazu, Takashi R Sato, Tatsuo Sat. Functional diversity of dopamine axons in prefrontal cortex during classical conditioning. eLife. vol 12. 2024-05-15. PMID:38747563. |
midbrain dopamine neurons impact neural processing in the prefrontal cortex (pfc) through mesocortical projections. |
2024-05-15 |
2024-05-27 |
mouse |
| Sofia Ines Garcia Moreno, Fabian Limani, Iina Ludwig, Catherine Gilbert, Christian Pifl, Thomas S Hnasko, Thomas Steinkellne. Viral overexpression of human alpha-synuclein in mouse substantia nigra dopamine neurons results in hyperdopaminergia but no neurodegeneration. bioRxiv : the preprint server for biology. 2024-05-15. PMID:38746104. |
loss of select neuronal populations such as midbrain dopamine (da) neurons is a pathological hallmark of parkinson's disease (pd). |
2024-05-15 |
2024-05-27 |
mouse |
| Hee Jae Jang, Royall McMahon Ward, Carla E M Golden, Christine M Constantinopl. Acetylcholine demixes heterogeneous dopamine signals for learning and moving. bioRxiv : the preprint server for biology. 2024-05-15. PMID:38746300. |
midbrain dopamine neurons promote reinforcement learning and movement vigor. |
2024-05-15 |
2024-05-27 |
rat |
| Samuel J Millard, Ivy B Hoang, Savannah Sherwood, Masakazu Taira, Vanessa Reyes, Zara Greer, Shayna L O'Connor, Kate M Wassum, Morgan H James, David J Barker, Melissa J Sharp. Cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency. Nature neuroscience. 2024-05-13. PMID:38741021. |
cognitive representations of intracranial self-stimulation of midbrain dopamine neurons depend on stimulation frequency. |
2024-05-13 |
2024-05-27 |
Not clear |
| Wolfram Schult. A dopamine mechanism for reward maximization. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 20. 2024-05-08. PMID:38717856. |
midbrain dopamine neurons code reward prediction errors (rpe) of subjective reward value suitable for rl. |
2024-05-08 |
2024-05-27 |
monkey |
| Yilin Tang, Yuting Li, Peiyu Cao, Yingbo Dong, Guoxin Xu, Qi Si, Runda Li, Yuxiu Su. Striatum and globus pallidus structural abnormalities in schizophrenia: A retrospective study of the different stages of the disease. Progress in neuro-psychopharmacology & biological psychiatry. 2024-05-01. PMID:38692473. |
the basal ganglia are important structures for the release of dopamine in the limbic circuits of the midbrain, and the striatum and globus pallidus are the major nuclei of the basal ganglia, and the dysfunction of these regions has been the basis of many models that have attempted to explain the underlying mechanisms of schizophrenia symptoms. |
2024-05-01 |
2024-05-04 |
Not clear |
| Suraj Cherian, Gabriel Simms, Liqiang Chen, Hong-Yuan Ch. Loss of Midbrain Dopamine Neurons Does Not Alter GABAergic Inhibition Mediated by Parvalbumin-Expressing Interneurons in Mouse Primary Motor Cortex. eNeuro. 2024-04-24. PMID:38658137. |
loss of midbrain dopamine neurons does not alter gabaergic inhibition mediated by parvalbumin-expressing interneurons in mouse primary motor cortex. |
2024-04-24 |
2024-04-28 |
mouse |
| Katerina Rademacher, Zak Doric, Dominik Haddad, Aphroditi Mamaligas, Szu-Chi Liao, Rose B Creed, Kohei Kano, Zac Chatterton, Yuhong Fu, Joseph H Garcia, Victoria Vance, Yoshitaka Sei, Anatol Kreitzer, Glenda M Halliday, Alexandra B Nelson, Elyssa B Margolis, Ken Nakamur. Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration. bioRxiv : the preprint server for biology. 2024-04-22. PMID:38645054. |
chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration. |
2024-04-22 |
2024-04-24 |
mouse |
| Ewa Galaj, Guo-Hua Bi, Zheng-Xiong X. β-caryophyllene inhibits heroin self-administration, but does not alter opioid-induced antinociception in rodents. Neuropharmacology. 2024-04-17. PMID:38631564. |
in this study, we found that systemic administration of bcp dose-dependently reduced heroin self-administration in rats under an fr2 schedule of reinforcement and partially blocked heroin-enhanced brain stimulation reward in dat-cre mice, maintained by optical stimulation of midbrain dopamine neurons at high frequencies. |
2024-04-17 |
2024-04-20 |
mouse |
| Cian-Fen Jhuo, Chun-Jung Chen, Jason T C Tzen, Wen-Ying Che. Teaghrelin protected dopaminergic neurons in MPTP-induced Parkinson's disease animal model by promoting PINK1/Parkin-mediated mitophagy and AMPK/SIRT1/PGC1-α-mediated mitochondrial biogenesis. Environmental toxicology. 2024-04-16. PMID:38622810. |
tyrosine hydroxylase and dopamine transporter protein were found reduced in the striatum and midbrain of mptp-treated mice, and significantly mitigated by teaghrelin supplementation. |
2024-04-16 |
2024-04-18 |
mouse |
| Cian-Fen Jhuo, Chun-Jung Chen, Jason T C Tzen, Wen-Ying Che. Teaghrelin protected dopaminergic neurons in MPTP-induced Parkinson's disease animal model by promoting PINK1/Parkin-mediated mitophagy and AMPK/SIRT1/PGC1-α-mediated mitochondrial biogenesis. Environmental toxicology. 2024-04-16. PMID:38622810. |
tyrosine hydroxylase and dopamine transporter protein were found reduced in the striatum and midbrain of mptp-treated mice, and significantly mitigated by teaghrelin supplementation. |
2024-04-16 |
2024-04-18 |
mouse |
| Xin Yi Ng, Mian Ca. Dysfunction of synaptic endocytic trafficking in Parkinson's disease. Neural regeneration research. vol 19. issue 12. 2024-04-10. PMID:38595283. |
this suggests that impaired synaptic vesicle recycling might represent an early feature of parkinson's disease, followed by axonal degeneration and the eventual loss of dopamine cell bodies in the midbrain via a "dying back" mechanism. |
2024-04-10 |
2024-04-12 |
mouse |
| Omar Soler-Cedeño, Hannah Alton, Guo-Hua Bi, Emily Linz, Lipin Ji, Alexandros Makriyannis, Zheng-Xiong X. AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-04-10. PMID:38600154. |
however, in optical intracranial self-stimulation (oicss) maintained by optogenetic stimulation of midbrain dopamine neurons in dat-cre mice, both am6527 and rimonabant dose-dependently inhibited dopamine-dependent oicss behavior. |
2024-04-10 |
2024-04-13 |
mouse |
| Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlman. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model. eLife. vol 12. 2024-04-08. PMID:38587883. |
transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a parkinsonism lesion model. |
2024-04-08 |
2024-04-10 |
mouse |
| Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlman. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model. eLife. vol 12. 2024-04-08. PMID:38587883. |
midbrain dopamine (mda) neurons comprise diverse cells with unique innervation targets and functions. |
2024-04-08 |
2024-04-10 |
mouse |
| Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J Young, Gabriella E Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J Magill, Paul D Dodso. Distributional coding of associative learning in discrete populations of midbrain dopamine neurons. Cell reports. vol 43. issue 4. 2024-04-06. PMID:38581677. |
distributional coding of associative learning in discrete populations of midbrain dopamine neurons. |
2024-04-06 |
2024-04-10 |
Not clear |