| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Matsubara, T Gonda, H Sawada, T Uezono, Y Kobayashi, T Kawamura, K Ohtaki, K Kimura, A Akaik. Endogenously occurring beta-carboline induces parkinsonism in nonprimate animals: a possible causative protoxin in idiopathic Parkinson's disease. Journal of neurochemistry. vol 70. issue 2. 1998-02-24. PMID:9453568. |
nh or 2-menh+ decreased dopamine (da) contents to 50-70% of values in controls in the striatum and midbrain. |
1998-02-24 |
2023-08-12 |
mouse |
| W Lu, M E Wol. Expression of dopamine transporter and vesicular monoamine transporter 2 mRNAs in rat midbrain after repeated amphetamine administration. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387873. |
expression of dopamine transporter and vesicular monoamine transporter 2 mrnas in rat midbrain after repeated amphetamine administration. |
1998-02-11 |
2023-08-12 |
rat |
| W Lu, M E Wol. Expression of dopamine transporter and vesicular monoamine transporter 2 mRNAs in rat midbrain after repeated amphetamine administration. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387873. |
thus, repeated amphetamine administration exerts modest and regionally selective effects on dat and vmat2 mrna expression in subpopulations of midbrain dopamine neurons. |
1998-02-11 |
2023-08-12 |
rat |
| J N Joyce, G Smutzer, C J Whitty, A Myers, M J Banno. Differential modification of dopamine transporter and tyrosine hydroxylase mRNAs in midbrain of subjects with Parkinson's, Alzheimer's with parkinsonism, and Alzheimer's disease. Movement disorders : official journal of the Movement Disorder Society. vol 12. issue 6. 1998-02-10. PMID:9399211. |
differential modification of dopamine transporter and tyrosine hydroxylase mrnas in midbrain of subjects with parkinson's, alzheimer's with parkinsonism, and alzheimer's disease. |
1998-02-10 |
2023-08-12 |
human |
| J N Joyce, G Smutzer, C J Whitty, A Myers, M J Banno. Differential modification of dopamine transporter and tyrosine hydroxylase mRNAs in midbrain of subjects with Parkinson's, Alzheimer's with parkinsonism, and Alzheimer's disease. Movement disorders : official journal of the Movement Disorder Society. vol 12. issue 6. 1998-02-10. PMID:9399211. |
the molecular characteristics of midbrain dopamine (da) neurons have been extensively studied in parkinson's disease (pd). |
1998-02-10 |
2023-08-12 |
human |
| J N Joyce, G Smutzer, C J Whitty, A Myers, M J Banno. Differential modification of dopamine transporter and tyrosine hydroxylase mRNAs in midbrain of subjects with Parkinson's, Alzheimer's with parkinsonism, and Alzheimer's disease. Movement disorders : official journal of the Movement Disorder Society. vol 12. issue 6. 1998-02-10. PMID:9399211. |
we examined the levels of tyrosine hydroxylase (th) protein, and the expression of th and dopamine transporter (dat) mrnas, in midbrain neurons of pd, ad, and ad/park cases. |
1998-02-10 |
2023-08-12 |
human |
| A M Sullivan, J Opacka-Juffry, G Hötten, J Pohl, S B Blun. Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson's disease. Neuroscience letters. vol 233. issue 2-3. 1998-01-29. PMID:9350835. |
post-mortem studies showed that gdf5 spared dopamine levels in the striatum and tyrosine hydroxylase positive neurones in the midbrain. |
1998-01-29 |
2023-08-12 |
rat |
| E A Fon, E N Pothos, B C Sun, N Killeen, D Sulzer, R H Edward. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron. vol 19. issue 6. 1998-01-29. PMID:9427250. |
using midbrain cultures from the mutant animals, amphetamine but not depolarization induces dopamine release. |
1998-01-29 |
2023-08-12 |
mouse |
| M K Sanghera, K Manaye, A McMahon, P K Sonsalla, D C Germa. Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. Neuroreport. vol 8. issue 15. 1997-12-22. PMID:9351666. |
dopamine transporter mrna levels are high in midbrain neurons vulnerable to mptp. |
1997-12-22 |
2023-08-12 |
mouse |
| V I Pidoplichko, M DeBiasi, J T Williams, J A Dan. Nicotine activates and desensitizes midbrain dopamine neurons. Nature. vol 390. issue 6658. 1997-12-19. PMID:9389479. |
nicotine activates and desensitizes midbrain dopamine neurons. |
1997-12-19 |
2023-08-12 |
Not clear |
| V I Pidoplichko, M DeBiasi, J T Williams, J A Dan. Nicotine activates and desensitizes midbrain dopamine neurons. Nature. vol 390. issue 6658. 1997-12-19. PMID:9389479. |
midbrain dopamine neurons normally help to shape behaviour by reinforcing biologically rewarding events, but addictive drugs such as cocaine can inappropriately exert a reinforcing influence by acting upon the mesolimbic dopamine system. |
1997-12-19 |
2023-08-12 |
Not clear |
| K Muneoka, M Mikuni, T Ogawa, K Kitera, K Kamei, M Takigawa, K Takahash. Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring. The American journal of physiology. vol 273. issue 5. 1997-12-16. PMID:9374808. |
in this study, it has been clearly demonstrated that prenatal dexamethasone treatment (dex; 0.05 mg/kg on gestational days 17, 18, and 19) resulted in the significant reductions of 5-hydroxytryptamine (5-ht) turnover in four brain regions, including the neocortex, hippocampus, hypothalamus, and midbrain + pons-medulla (m + p-m) but not in the striatum in the offspring at 3 and 14 wk of life, as well as dopamine turnover in the hypothalamus. |
1997-12-16 |
2023-08-12 |
rat |
| B Pardo, C L Paíno, M J Casarejos, M A Men. Neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons. Brain research. Brain research protocols. vol 1. issue 2. 1997-12-16. PMID:9385075. |
neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons. |
1997-12-16 |
2023-08-12 |
rat |
| S W Johnso. Afferent control of midbrain dopamine neurons: an intracellular perspective. Advances in pharmacology (San Diego, Calif.). vol 42. 1997-11-25. PMID:9327993. |
afferent control of midbrain dopamine neurons: an intracellular perspective. |
1997-11-25 |
2023-08-12 |
Not clear |
| M A Mena, M J Casarejos, A Carazo, C L Paíno, J García de Yébene. Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 4-5. 1997-11-21. PMID:9295168. |
glia protect fetal midbrain dopamine neurons in culture from l-dopa toxicity through multiple mechanisms. |
1997-11-21 |
2023-08-12 |
Not clear |
| M A Mena, M J Casarejos, A Carazo, C L Paíno, J García de Yébene. Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 4-5. 1997-11-21. PMID:9295168. |
we investigated the protective effect against l-dopa neurotoxicity in midbrain dopamine neurons of fractions of different molecular size of glia conditioned medium and candidate neuroprotective agents produced by glia including neurotrophic factors and antioxidants. |
1997-11-21 |
2023-08-12 |
Not clear |
| M A Mena, M J Casarejos, A Carazo, C L Paíno, J García de Yébene. Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 4-5. 1997-11-21. PMID:9295168. |
glutathione, had neurotrophic effects on untreated midbrain dopamine neurons and prevented the effect of l-dopa. |
1997-11-21 |
2023-08-12 |
Not clear |
| Y Otsubo, H Ito, T Shibuy. Intracerebral monoamine concentration after ventriculoperitoneal shunting in the congenital hydrocephalus rat. Neurologia medico-chirurgica. vol 37. issue 9. 1997-11-21. PMID:9330530. |
high performance liquid chromatography (hplc) was used to measure the concentrations of dopamine (da), norepinephrine (ne), serotonin, homovanillic acid (hva), 3-methoxyl-4-hydroxyphenylenglycol, 5-hydroxy-indolacetic acid (5-hiaa), and 3,4-dihydroxyphenylacetic acid in the whole cerebral cortex, the thalamus and hypothalamus, the midbrain, the lower brainstem, the cerebellum, and the striatum. |
1997-11-21 |
2023-08-12 |
rat |
| M A Mena, V Davila, D Sulze. Neurotrophic effects of L-DOPA in postnatal midbrain dopamine neuron/cortical astrocyte cocultures. Journal of neurochemistry. vol 69. issue 4. 1997-10-27. PMID:9326268. |
neurotrophic effects of l-dopa in postnatal midbrain dopamine neuron/cortical astrocyte cocultures. |
1997-10-27 |
2023-08-12 |
Not clear |
| M A Mena, V Davila, D Sulze. Neurotrophic effects of L-DOPA in postnatal midbrain dopamine neuron/cortical astrocyte cocultures. Journal of neurochemistry. vol 69. issue 4. 1997-10-27. PMID:9326268. |
we tested the effect of l-dopa on dopamine neurons using postnatal ventral midbrain neuron/cortical astrocyte cocultures in serum-free, glia-conditioned medium. |
1997-10-27 |
2023-08-12 |
Not clear |