| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M T Antonio, I Corpas, M L Lere. Neurochemical changes in newborn rat's brain after gestational cadmium and lead exposure. Toxicology letters. vol 104. issue 1-2. 1999-03-09. PMID:10048743. |
on the other hand, we found a significant increase of indoleamine content in all brain areas studied in the cadmium-lead group and so the dopamine and its metabolite in mesencephalon, whereas dopamine levels in metencephalon decreased significantly. |
1999-03-09 |
2023-08-12 |
rat |
| N B Mercuri, M Scarponi, A Bonci, A Siniscalchi, G Bernard. Monoamine oxidase inhibition causes a long-term prolongation of the dopamine-induced responses in rat midbrain dopaminergic cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 7. 1999-02-25. PMID:9065488. |
the way monoamine oxidase (mao) modulates the depression of the firing rate and the hyperpolarization of the membrane caused by dopamine (da) on rat midbrain dopaminergic cells was investigated by means of intracellular recordings in vitro. |
1999-02-25 |
2023-08-12 |
rat |
| G Kapatos, K Hirayama, M Shimoji, S Milstie. GTP cyclohydrolase I feedback regulatory protein is expressed in serotonin neurons and regulates tetrahydrobiopterin biosynthesis. Journal of neurochemistry. vol 72. issue 2. 1999-02-11. PMID:9930739. |
gfrp mrna expression was abundant in serotonin neurons of the dorsal raphe nucleus but was undetectable in dopamine neurons of the midbrain or norepinephrine neurons of the locus coeruleus. |
1999-02-11 |
2023-08-12 |
rat |
| G Kapatos, K Hirayama, M Shimoji, S Milstie. GTP cyclohydrolase I feedback regulatory protein is expressed in serotonin neurons and regulates tetrahydrobiopterin biosynthesis. Journal of neurochemistry. vol 72. issue 2. 1999-02-11. PMID:9930739. |
primary neuronal cultures were used to examine the role of gfrp-mediated regulation of gtpch on tetrahydrobiopterin synthesis within brainstem serotonin neurons and midbrain dopamine neurons. |
1999-02-11 |
2023-08-12 |
rat |
| H Ehara, Y Maegaki, K Takeshit. Neuroleptic malignant syndrome and methylphenidate. Pediatric neurology. vol 19. issue 4. 1999-02-10. PMID:9831002. |
however, methylphenidate is a dopamine agonist via the inhibition of uptake of dopamine, and therefore dopaminergic systems in the brainstem (mainly the midbrain) and the spinal cord were unlikely to participate in the onset of this syndrome. |
1999-02-10 |
2023-08-12 |
Not clear |
| B A Cox, S W Johnso. Nitric oxide facilitates N-methyl-D-aspartate-induced burst firing in dopamine neurons from rat midbrain slices. Neuroscience letters. vol 255. issue 3. 1999-02-10. PMID:9832190. |
nitric oxide facilitates n-methyl-d-aspartate-induced burst firing in dopamine neurons from rat midbrain slices. |
1999-02-10 |
2023-08-12 |
rat |
| J Kume-Kick, M E Ric. Dependence of dopamine calibration factors on media Ca2+ and Mg2+ at carbon-fiber microelectrodes used with fast-scan cyclic voltammetry. Journal of neuroscience methods. vol 84. issue 1-2. 1999-01-26. PMID:9821634. |
because extracellular ca2+ concentration ([ca2+]o) can fall under stimulation conditions used to elicit dopamine release, we also evaluated the size of stimulated [ca2+]o shifts in guinea pig midbrain slices using ion-selective microelectrodes. |
1999-01-26 |
2023-08-12 |
Not clear |
| R Grondin, D M Gas. Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson's disease. Journal of neurology. vol 245. issue 11 Suppl 3. 1999-01-22. PMID:9808338. |
considerable effort has been devoted to the search for molecules that might exert trophic influences on midbrain dopamine neurons, and potentially be of therapeutic value in the treatment of parkinson's disease. |
1999-01-22 |
2023-08-12 |
monkey |
| R Grondin, D M Gas. Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson's disease. Journal of neurology. vol 245. issue 11 Suppl 3. 1999-01-22. PMID:9808338. |
in addition to its effects on cultured fetal midbrain dopamine neurons, gdnf promotes recovery of the injured nigrostriatal dopamine system and improves motor functions in rodent and nonhuman primate models of parkinson's disease. |
1999-01-22 |
2023-08-12 |
monkey |
| R Grondin, D M Gas. Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson's disease. Journal of neurology. vol 245. issue 11 Suppl 3. 1999-01-22. PMID:9808338. |
in this model, adult midbrain dopamine neurons stimulated by gdnf show increased cell size, neuritic extent, and expression of phenotypic markers. |
1999-01-22 |
2023-08-12 |
monkey |
| C Broberger, D Blacker, L Giménez-Llort, M Herrera-Marschitz, S O Ogren, T Hökfel. Modulation of motor behaviour by NMDA- and cholecystokinin-antagonism. Amino acids. vol 14. issue 1-3. 1999-01-13. PMID:9871437. |
antagonistic influences in this region are exerted by afferent projections from, on the one hand, the ventral mesencephalon, utilizing dopamine as a transmitter, and, on the other hand, from the cerebral cortex, signalling by the excitatory amino acid glutamate. |
1999-01-13 |
2023-08-12 |
Not clear |
| G U Höglinger, J Sautter, M Meyer, C Spenger, R W Seiler, W H Oertel, H R Widme. Rat fetal ventral mesencephalon grown as solid tissue cultures: influence of culture time and BDNF treatment on dopamine neuron survival and function. Brain research. vol 813. issue 2. 1999-01-05. PMID:9838177. |
rat fetal ventral mesencephalon grown as solid tissue cultures: influence of culture time and bdnf treatment on dopamine neuron survival and function. |
1999-01-05 |
2023-08-12 |
human |
| K Z Shen, S W Johnso. Sodium pump evokes high density pump currents in rat midbrain dopamine neurons. The Journal of physiology. vol 512 ( Pt 2). 1998-12-29. PMID:9763634. |
sodium pump evokes high density pump currents in rat midbrain dopamine neurons. |
1998-12-29 |
2023-08-12 |
rat |
| K Z Shen, S W Johnso. Sodium pump evokes high density pump currents in rat midbrain dopamine neurons. The Journal of physiology. vol 512 ( Pt 2). 1998-12-29. PMID:9763634. |
our results are consistent with the physiological role of the sodium pump in burst firing in midbrain dopamine neurons |
1998-12-29 |
2023-08-12 |
rat |
| R H Belmaker, N Grisar. Magnetic stimulation of the brain in animal depression models responsive to ECS. The journal of ECT. vol 14. issue 3. 1998-12-23. PMID:9773358. |
in the striatum and hippocampus, dopamine levels were increased by 25 +/- 1.5% and 18 +/- 0.8%, respectively, but were reduced in frontal cortex and decreased in the striatum and hippocampus in the tms-treated rats with no change to the midbrain. |
1998-12-23 |
2023-08-12 |
rat |
| L García-Gil, J A Ramos, T Rubino, D Parolaro, J J Fernández-Rui. Perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mRNA levels in midbrain dopaminergic neurons of adult male and female rats. Neurotoxicology and teratology. vol 20. issue 5. 1998-12-17. PMID:9761594. |
perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mrna levels in midbrain dopaminergic neurons of adult male and female rats. |
1998-12-17 |
2023-08-12 |
rat |
| C Cosi, M Marie. Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP): prevention by the poly(ADP-ribose) polymerase inhibitor, benzamide. Brain research. vol 809. issue 1. 1998-12-16. PMID:9795136. |
]; (2) show that mptp causes a regionally-dependent (striatal and midbrain) loss of nad+; (3) indicate that the parp inhibitor benzamide can prevent these losses without interfering with mptp-induced striatal dopamine release; and (4) provide further evidence to suggest an involvement of parp in mptp-induced neurotoxicity in vivo. |
1998-12-16 |
2023-08-12 |
mouse |
| E Guatteo, N B Mercuri, G Bernardi, T Knöpfe. Intracellular sodium and calcium homeostasis during hypoxia in dopamine neurons of rat substantia nigra pars compacta. Journal of neurophysiology. vol 80. issue 5. 1998-12-08. PMID:9819239. |
we investigated the hypoxia-induced disturbance of cytosolic sodium concentration ([na+]i) and of cytosolic calcium concentration ([ca2+]i) in dopamine neurons of the substantia nigra pars compacta in rat midbrain slices, by combining whole cell patch-clamp recordings and microfluorometry. |
1998-12-08 |
2023-08-12 |
rat |
| P J Fletcher, K M Korth, M S Sabijan, N J DeSous. Injections of D-amphetamine into the ventral pallidum increase locomotor activity and responding for conditioned reward: a comparison with injections into the nucleus accumbens. Brain research. vol 805. issue 1-2. 1998-11-25. PMID:9733910. |
the nucleus accumbens and ventral pallidum receive dopamine (da) projections from the mesencephalon. |
1998-11-25 |
2023-08-12 |
Not clear |
| K Ikemoto, I Nagatsu, A Nishimura, K Nishi, R Ara. Do all of human midbrain tyrosine hydroxylase neurons synthesize dopamine? Brain research. vol 805. issue 1-2. 1998-11-25. PMID:9733977. |
do all of human midbrain tyrosine hydroxylase neurons synthesize dopamine? |
1998-11-25 |
2023-08-12 |
human |