| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fang Zheng, Steven W Johnso. Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro. Brain research. vol 948. issue 1-2. 2002-10-30. PMID:12383971. |
our results point out a selective involvement of group i mglurs in facilitating burst firing of midbrain dopamine cells. |
2002-10-30 |
2023-08-12 |
rat |
| Richard Grondin, Zhiming Zhang, Ai Yi, Wayne A Cass, Navin Maswood, Anders H Andersen, Dennis D Elsberry, Michael C Klein, Greg A Gerhardt, Don M Gas. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain : a journal of neurology. vol 125. issue Pt 10. 2002-10-29. PMID:12244077. |
the powerful trophic effects that glial cell line-derived neurotrophic factor (gdnf) exerts on midbrain dopamine neurones suggest its use in treating parkinson's disease. |
2002-10-29 |
2023-08-12 |
monkey |
| Susan L Ingram, Balakrishna M Prasad, Susan G Amar. Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons. Nature neuroscience. vol 5. issue 10. 2002-10-22. PMID:12352983. |
dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons. |
2002-10-22 |
2023-08-12 |
rat |
| Virginia M Pickel, Miguel Garzón, Elisa Mengua. Electron microscopic immunolabeling of transporters and receptors identifies transmitter-specific functional sites envisioned in Cajal's neuron. Progress in brain research. vol 136. 2002-09-19. PMID:12143378. |
dopamine terminals in the striatum and ventral pallidum, as well as dendrites of midbrain dopaminergic neurons in the ventral tegmental area and substantia nigra express the plasmalemmal dopamine transporter (dat) and the vesicular monoamine transporter (vmat2). |
2002-09-19 |
2023-08-12 |
Not clear |
| Guy Arnold, Klaus Tatsch, Eduardo Kraft, Wolfgang H Oertel, Johannes Schwar. Steele-Richardson-Olszewski-syndrome: reduction of dopamine D2 receptor binding relates to the severity of midbrain atrophy in vivo: (123)IBZM SPECT and MRI study. Movement disorders : official journal of the Movement Disorder Society. vol 17. issue 3. 2002-09-16. PMID:12112207. |
steele-richardson-olszewski-syndrome: reduction of dopamine d2 receptor binding relates to the severity of midbrain atrophy in vivo: (123)ibzm spect and mri study. |
2002-09-16 |
2023-08-12 |
Not clear |
| Nigel T Maidment, Yiling Chen, Aiko M Tan, Niall P Murphy, Frances M Lesli. Rat ventral midbrain dopamine neurons express the orphanin FQ/nociceptin receptor ORL-1. Neuroreport. vol 13. issue 9. 2002-09-10. PMID:12151756. |
rat ventral midbrain dopamine neurons express the orphanin fq/nociceptin receptor orl-1. |
2002-09-10 |
2023-08-12 |
rat |
| David N Ruskin, Debra A Bergstrom, Judith R Walter. Nigrostriatal lesion and dopamine agonists affect firing patterns of rodent entopeduncular nucleus neurons. Journal of neurophysiology. vol 88. issue 1. 2002-09-06. PMID:12091570. |
altered activity of the entopeduncular nucleus, the rodent homologue of the globus pallidus internal segment in primates, is thought to mediate behavioral consequences of midbrain dopamine depletion in rodents. |
2002-09-06 |
2023-08-12 |
rat |
| David N Ruskin, Debra A Bergstrom, Judith R Walter. Nigrostriatal lesion and dopamine agonists affect firing patterns of rodent entopeduncular nucleus neurons. Journal of neurophysiology. vol 88. issue 1. 2002-09-06. PMID:12091570. |
the results support the view that dysfunction in the basal ganglia after midbrain dopamine neuron loss relates more consistently to abnormal activity patterns than to net changes in firing rate in the basal ganglia output nuclei, while overall decreases in firing rate in these structures may play a more important role in adverse motor reactions to dopamine agonist treatments. |
2002-09-06 |
2023-08-12 |
rat |
| D M Yurek, A Fletcher-Turner, J Moore, L Chai, N Mahanthapp. Co-grafts of fetal ventral mesencephalon and fibroblasts expressing sonic hedgehog: effect on survival and function of dopamine grafts. Cell transplantation. vol 10. issue 8. 2002-09-05. PMID:11814108. |
co-grafts of fetal ventral mesencephalon and fibroblasts expressing sonic hedgehog: effect on survival and function of dopamine grafts. |
2002-09-05 |
2023-08-12 |
rat |
| John G Temple, Diane B Miller, George T Barthalmu. Differential vulnerability of snake species to MPTP: a behavioral and biochemical comparison in ratsnakes (Elaphe) and watersnakes (Nerodia). Neurotoxicology and teratology. vol 24. issue 2. 2002-08-27. PMID:11943510. |
we report that mptp induces depletion of norepinephrine and serotonin in fore, mid and hindbrain regions and depletion of dopamine in fore and midbrain regions in e.o. |
2002-08-27 |
2023-08-12 |
Not clear |
| A D Miller, G L Forster, K M Metcalf, C D Blah. Excitotoxic lesions of the pedunculopontine differentially mediate morphine- and d-amphetamine-evoked striatal dopamine efflux and behaviors. Neuroscience. vol 111. issue 2. 2002-08-13. PMID:11983320. |
cholinergic and glutamatergic cells in the pedunculopontine tegmental nucleus are a principal source of excitatory input to midbrain dopamine neurons projecting to the striatum. |
2002-08-13 |
2023-08-12 |
rat |
| J Fadel, A Y Deutc. Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience. vol 111. issue 2. 2002-08-13. PMID:11983323. |
we examined the anatomical relationships between orexin and dopamine neurons in rats, with particular attention to characterizing the lateral hypothalamic projection to midbrain dopamine neurons. |
2002-08-13 |
2023-08-12 |
rat |
| Stephanie Dallvechia-Adams, Michael J Kuhar, Yoland Smit. Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons. The Journal of comparative neurology. vol 448. issue 4. 2002-08-06. PMID:12115699. |
cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons. |
2002-08-06 |
2023-08-12 |
rat |
| Natsuki Matsushita, Hideki Okada, Yasunobu Yasoshima, Kazuaki Takahashi, Kazutoshi Kiuchi, Kazuto Kobayash. Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development. Journal of neurochemistry. vol 82. issue 2. 2002-08-06. PMID:12124430. |
dopamine (da)-producing neurons in the ventral midbrain are generated from a specified neuronal lineage and form selective axonal pathways that mediate multiple cns functions. |
2002-08-06 |
2023-08-12 |
mouse |
| Arthur C Riegel, Edward D Frenc. Abused inhalants and central reward pathways: electrophysiological and behavioral studies in the rat. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105104. |
exposure of rats to 11,000 ppm of inhaled toluene produced time-dependent activation of dopamine neurons within the midbrain ventral tegmental area (vta). |
2002-08-02 |
2023-08-12 |
rat |
| Jong-Hoon Kim, Jonathan M Auerbach, José A Rodríguez-Gómez, Iván Velasco, Denise Gavin, Nadya Lumelsky, Sang-Hun Lee, John Nguyen, Rosario Sánchez-Pernaute, Krys Bankiewicz, Ron McKa. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature. vol 418. issue 6893. 2002-07-30. PMID:12077607. |
parkinson's disease is a widespread condition caused by the loss of midbrain neurons that synthesize the neurotransmitter dopamine. |
2002-07-30 |
2023-08-12 |
mouse |
| Jong-Hoon Kim, Jonathan M Auerbach, José A Rodríguez-Gómez, Iván Velasco, Denise Gavin, Nadya Lumelsky, Sang-Hun Lee, John Nguyen, Rosario Sánchez-Pernaute, Krys Bankiewicz, Ron McKa. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature. vol 418. issue 6893. 2002-07-30. PMID:12077607. |
the dopamine neurons generated by these stem cells show electrophysiological and behavioural properties expected of neurons from the midbrain. |
2002-07-30 |
2023-08-12 |
mouse |
| Pekka Rauhala, Tsugunobu Andoh, Kevin Yeh, Chuang C Chiue. Contradictory effects of sodium nitroprusside and S-nitroso-N-acetylpenicillamine on oxidative stress in brain dopamine neurons in vivo. Annals of the New York Academy of Sciences. vol 962. 2002-07-26. PMID:12076963. |
intranigral infusion of ferrous citrate (4.2 nmol) into the rat midbrain substantia nigra compacta area caused acute lipid peroxidation in the substantia nigra and chronic dopamine depletion in the caudate nucleus. |
2002-07-26 |
2023-08-12 |
rat |
| Sophie Erhardt, Jan M Mathé, Karima Chergui, Göran Engberg, Torgny H Svensso. GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 3. 2002-07-22. PMID:11882912. |
previous work demonstrates the fundamental role of the firing pattern, specifically the burst firing mode of midbrain dopamine (da) neurons in the regulation of da release. |
2002-07-22 |
2023-08-12 |
rat |
| C Nocjar, B L Roth, E A Pehe. Localization of 5-HT(2A) receptors on dopamine cells in subnuclei of the midbrain A10 cell group. Neuroscience. vol 111. issue 1. 2002-07-18. PMID:11955720. |
localization of 5-ht(2a) receptors on dopamine cells in subnuclei of the midbrain a10 cell group. |
2002-07-18 |
2023-08-12 |
rat |