| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marc Turiault, Sébastien Parnaudeau, Aude Milet, Rosanna Parlato, Jean-Denis Rouzeau, Monique Lazar, François Tronch. Analysis of dopamine transporter gene expression pattern -- generation of DAT-iCre transgenic mice. The FEBS journal. vol 274. issue 14. 2007-08-30. PMID:17565601. |
in situ studies showed that beta-galactosidase (5-bromo-4-chloroindol-3-yl beta-d-galactoside staining) and the dopamine transporter (immunofluorescence) had identical distributions in the ventral midbrain. |
2007-08-30 |
2023-08-12 |
mouse |
| Päivi Lindholm, Merja H Voutilainen, Juha Laurén, Johan Peränen, Veli-Matti Leppänen, Jaan-Olle Andressoo, Maria Lindahl, Sanna Janhunen, Nisse Kalkkinen, Tõnis Timmusk, Raimo K Tuominen, Mart Saarm. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature. vol 448. issue 7149. 2007-08-27. PMID:17611540. |
novel neurotrophic factor cdnf protects and rescues midbrain dopamine neurons in vivo. |
2007-08-27 |
2023-08-12 |
mouse |
| Yoshinori Masuo, Masami Ishido, Masatoshi Morita, Hirofumi Sawa, Kazuo Nagashima, Etsuo Nik. Behavioural characteristics and gene expression in the hyperactive wiggling (Wig) rat. The European journal of neuroscience. vol 25. issue 12. 2007-08-24. PMID:17610585. |
dopamine transporter gene expression was increased in the dorsal midbrain but decreased in the ventral midbrain, a pattern distinct from that induced by 6-hydroxydopamine. |
2007-08-24 |
2023-08-12 |
rat |
| Philippe Huot, André Paren. Dopaminergic neurons intrinsic to the striatum. Journal of neurochemistry. vol 101. issue 6. 2007-08-16. PMID:17286588. |
the dopaminergic nature of these neurons is further supported by the fact that they express the dopamine (da) transporter (dat) and the nuclear orphan receptor nurr1, a transcription factor essential for the expression of the da phenotype by midbrain neurons. |
2007-08-16 |
2023-08-12 |
Not clear |
| Masayuki Matsumoto, Okihide Hikosak. Lateral habenula as a source of negative reward signals in dopamine neurons. Nature. vol 447. issue 7148. 2007-08-08. PMID:17522629. |
midbrain dopamine neurons are key components of the brain's reward system, which is thought to guide reward-seeking behaviours. |
2007-08-08 |
2023-08-12 |
monkey |
| Huifang Ji, Paul D Shepar. Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 26. 2007-08-01. PMID:17596440. |
lateral habenula stimulation inhibits rat midbrain dopamine neurons through a gaba(a) receptor-mediated mechanism. |
2007-08-01 |
2023-08-12 |
rat |
| Huifang Ji, Paul D Shepar. Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 26. 2007-08-01. PMID:17596440. |
transient changes in the activity of midbrain dopamine neurons encode an error signal that contributes to associative learning. |
2007-08-01 |
2023-08-12 |
rat |
| Huifang Ji, Paul D Shepar. Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 26. 2007-08-01. PMID:17596440. |
these data suggest that lhb-induced suppression of dopamine cell activity is mediated indirectly by orthodromic activation of putative gabaergic neurons in the ventral midbrain. |
2007-08-01 |
2023-08-12 |
rat |
| Yasushi Kobayashi, Ken-Ichi Okad. Reward prediction error computation in the pedunculopontine tegmental nucleus neurons. Annals of the New York Academy of Sciences. vol 1104. 2007-07-25. PMID:17344541. |
several lines of evidence support the reward-based learning theory proposing that midbrain dopamine (da) neurons send a teaching signal (the reward prediction error signal) to control synaptic plasticity of the projection area. |
2007-07-25 |
2023-08-12 |
monkey |
| Gan-Lan Bian, Li-Chun Wei, Mei Shi, Yan-Qin Wang, Rong Cao, Liang-Wei Che. Fluoro-Jade C can specifically stain the degenerative neurons in the substantia nigra of the 1-methyl-4-phenyl-1,2,3,6-tetrahydro pyridine-treated C57BL/6 mice. Brain research. vol 1150. 2007-07-24. PMID:17397812. |
in the midbrain of mptp-treated mice, fluoro-jade c-positive neuronal cells were exclusively distributed in the substantia nigra pars compacta, but rarely seen in the ventral tegemental area where dopamine neurons were numerously distributed. |
2007-07-24 |
2023-08-12 |
mouse |
| Yonjung Kim, Myoung Kyu Park, Dae-Yong Uhm, Sungkwon Chun. Modulation of T-type Ca2+ channels by corticotropin-releasing factor through protein kinase C pathway in MN9D dopaminergic cells. Biochemical and biophysical research communications. vol 358. issue 3. 2007-07-20. PMID:17506983. |
even though crf receptors are present in the midbrain dopamine neurons, the cellular mechanism of crf action is not clear yet. |
2007-07-20 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. Attention-deficit hyperactivity disorder may be associated with decreased central brain-derived neurotrophic factor activity: clinical and therapeutic implications. Medical hypotheses. vol 68. issue 4. 2007-07-18. PMID:16919891. |
drawing on findings from studies into the drugs for adhd relating to central bdnf expression, hyperactivity in bdnf knockout mice, bdnf effects in midbrain dopaminergic function and the close association between bdnf and the dopamine transporter (an important molecule for adhd pathogenesis), it is proposed here that decreased central bdnf, particularly in the midbrain region, may play an important role in the pathogenesis adhd. |
2007-07-18 |
2023-08-12 |
mouse |
| Nicholas M Kanaan, Jeffrey H Kordower, Timothy J Collie. Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability. The Journal of comparative neurology. vol 502. issue 5. 2007-07-18. PMID:17436290. |
age-related accumulation of marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability. |
2007-07-18 |
2023-08-12 |
monkey |
| Asa Abeliovich, Rachel Hammon. Midbrain dopamine neuron differentiation: factors and fates. Developmental biology. vol 304. issue 2. 2007-07-12. PMID:17331494. |
midbrain dopamine neuron differentiation: factors and fates. |
2007-07-12 |
2023-08-12 |
Not clear |
| Kiyoshi Egami, Silaja Yitta, Suhail Kasim, J Chris Lewers, Rosalinda C Roberts, Mohamed Lehar, H A Jinna. Basal ganglia dopamine loss due to defect in purine recycling. Neurobiology of disease. vol 26. issue 2. 2007-06-28. PMID:17374562. |
several rare inherited disorders have provided valuable experiments of nature highlighting specific biological processes of particular importance to the survival or function of midbrain dopamine neurons. |
2007-06-28 |
2023-08-12 |
mouse |
| Kiyoshi Egami, Silaja Yitta, Suhail Kasim, J Chris Lewers, Rosalinda C Roberts, Mohamed Lehar, H A Jinna. Basal ganglia dopamine loss due to defect in purine recycling. Neurobiology of disease. vol 26. issue 2. 2007-06-28. PMID:17374562. |
in the current studies of knockout mice, no morphological signs of abnormal development or degeneration were found in an exhaustive battery that included stereological and morphometric measures of midbrain dopamine neurons, electron microscopic studies of striatal axons and terminals, and stains for degeneration or gliosis. |
2007-06-28 |
2023-08-12 |
mouse |
| Bret A Morrow, Robert H Roth, D Eugene Redmond, John R Sladek, John D Elswort. Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation. Experimental neurology. vol 204. issue 2. 2007-06-26. PMID:17313945. |
apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation. |
2007-06-26 |
2023-08-12 |
rat |
| Bret A Morrow, Robert H Roth, D Eugene Redmond, John R Sladek, John D Elswort. Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation. Experimental neurology. vol 204. issue 2. 2007-06-26. PMID:17313945. |
we decided to examine the timing and extent of ncd of the midbrain dopamine system in a primate species, as dopamine deficiency or excess has been implicated in several disorders. |
2007-06-26 |
2023-08-12 |
rat |
| Bret A Morrow, Robert H Roth, D Eugene Redmond, John R Sladek, John D Elswort. Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation. Experimental neurology. vol 204. issue 2. 2007-06-26. PMID:17313945. |
thus, marked apoptotic ncd occurs in the primate midbrain dopamine system half-way through gestation, and appears to be associated with the rapid developmental increase in striatal dopamine innervation. |
2007-06-26 |
2023-08-12 |
rat |
| Mona Bains, Joanne C Cousins, James L Robert. Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon. Experimental neurology. vol 204. issue 2. 2007-06-26. PMID:17320868. |
neuroprotection by estrogen against mpp+-induced dopamine neuron death is mediated by eralpha in primary cultures of mouse mesencephalon. |
2007-06-26 |
2023-08-12 |
mouse |