| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minoru Narita, Yasuyuki Nagumo, Mayumi Miyatake, Daigo Ikegami, Kana Kurahashi, Tsutomu Suzuk. Implication of protein kinase C in the orexin-induced elevation of extracellular dopamine levels and its rewarding effect. The European journal of neuroscience. vol 25. issue 5. 2007-06-25. PMID:17425580. |
in the present study, we investigated the role of orexinergic systems in the activation of midbrain dopamine neurons. |
2007-06-25 |
2023-08-12 |
Not clear |
| Jun Wang, Sharon K Michelhaugh, Michael J Banno. Valproate robustly increases Sp transcription factor-mediated expression of the dopamine transporter gene within dopamine cells. The European journal of neuroscience. vol 25. issue 7. 2007-06-21. PMID:17439486. |
utilizing a human dopaminergic cell line and rat midbrain dopamine (da) neurons in organotypic culture, we found that valproate increased endogenous dat gene expression in a concentration- and time-dependent manner. |
2007-06-21 |
2023-08-12 |
human |
| Saleem M Nicol. The nucleus accumbens as part of a basal ganglia action selection circuit. Psychopharmacology. vol 191. issue 3. 2007-06-12. PMID:16983543. |
recent hypotheses propose that the accumbens and its dopamine projection from the midbrain contribute to appetitive behaviors required to obtain reward. |
2007-06-12 |
2023-08-12 |
Not clear |
| Stephen Sammut, Kristina E Bray, Anthony R Wes. Dopamine D2 receptor-dependent modulation of striatal NO synthase activity. Psychopharmacology. vol 191. issue 3. 2007-06-12. PMID:17206493. |
striatal nitric oxide (no)-producing interneurons receive synaptic contacts from midbrain dopamine (da) neurons and are regulated by phasic da transmission. |
2007-06-12 |
2023-08-12 |
rat |
| Marco Leyton, Marije aan het Rot, Linda Booij, Glen B Baker, Simon N Young, Chawki Benkelfa. Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion. Journal of psychiatry & neuroscience : JPN. vol 32. issue 2. 2007-06-08. PMID:17353942. |
midbrain dopamine transmission is thought to regulate responses to rewarding drugs and drug-paired stimuli; however, the exact contribution, particularly in humans, remains unclear. |
2007-06-08 |
2023-08-12 |
Not clear |
| Bernard L Schneider, Corey R Seehus, Elizabeth E Capowski, Patrick Aebischer, Su-Chun Zhang, Clive N Svendse. Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation. Human molecular genetics. vol 16. issue 6. 2007-06-06. PMID:17309880. |
consistent with the selective vulnerability of ventral midbrain dopaminergic neurons, alpha-synuclein cytotoxicity appeared most pronounced following fgf8/shh specification and was decreased by inhibition of dopamine synthesis. |
2007-06-06 |
2023-08-12 |
human |
| Changgeng Peng, Songhua Fan, Xuping Li, Xiaolan Fan, Ming Ming, Zhe Sun, Weidong L. Overexpression of pitx3 upregulates expression of BDNF and GDNF in SH-SY5Y cells and primary ventral mesencephalic cultures. FEBS letters. vol 581. issue 7. 2007-06-06. PMID:17350004. |
the transcription factor pitx3 plays an important role in the development of midbrain to promote the growth and differentiation of dopamine neurons. |
2007-06-06 |
2023-08-12 |
Not clear |
| Minchan Gil, Cushla McKinney, Mi Kyeong Lee, Jeffrey B Eells, Marcia A Phyillaier, Vera M Nikode. Regulation of GTP cyclohydrolase I expression by orphan receptor Nurr1 in cell culture and in vivo. Journal of neurochemistry. vol 101. issue 1. 2007-05-29. PMID:17394463. |
nurr1 is an orphan nuclear transcription factor essential for the terminal differentiation of dopamine (da) neurons in the ventral midbrain (vm). |
2007-05-29 |
2023-08-12 |
mouse |
| Adam J Schwarz, Alessandro Gozzi, Torsten Reese, Angelo Bifon. Functional connectivity in the pharmacologically activated brain: resolving networks of correlated responses to d-amphetamine. Magnetic resonance in medicine. vol 57. issue 4. 2007-05-24. PMID:17390353. |
a cluster analysis resolved three distinct networks of brain regions that exhibited closely coupled responses: one corresponding to primary dopamine projections from the midbrain to the striatum, a second consisting predominantly of forebrain cortical and basal ganglia regions that share a widespread correlation pattern resembling the univariate group response, and a third including structures in the periventricular dopamine system. |
2007-05-24 |
2023-08-12 |
rat |
| L Azam, Y Chen, F M Lesli. Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons. Neuroscience. vol 144. issue 4. 2007-05-21. PMID:17197101. |
developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons. |
2007-05-21 |
2023-08-12 |
rat |
| Jae-Won Shim, Chang-Hwan Park, Yong-Chul Bae, Jin-Young Bae, Seungsoo Chung, Mi-Yoon Chang, Hyun-Chul Koh, Hyun-Seob Lee, Se-Jin Hwang, Ki-Hwan Lee, Yong-Sung Lee, Cha-Yong Choi, Sang-Hun Le. Generation of functional dopamine neurons from neural precursor cells isolated from the subventricular zone and white matter of the adult rat brain using Nurr1 overexpression. Stem cells (Dayton, Ohio). vol 25. issue 5. 2007-05-16. PMID:17234994. |
forced expression of nurr1, a transcriptional factor specific to midbrain dopamine (da) neuron development, caused in the adult cells an acquisition of the da neurotransmitter phenotype and sufficient differentiation toward morphologically, phenotypically, and ultrastructurally mature da neurons. |
2007-05-16 |
2023-08-12 |
rat |
| Thomas Carlsson, Tomas Björklund, Deniz Kiri. Restoration of the striatal dopamine synthesis for Parkinson's disease: viral vector-mediated enzyme replacement strategy. Current gene therapy. vol 7. issue 2. 2007-05-16. PMID:17430130. |
it is charaterized by a progressive loss of dopamine (da) producing neurons in the midbrain, which result in a decline of da innervations present in the forebrain, in particular, the striatum. |
2007-05-16 |
2023-08-12 |
Not clear |
| G M Halliday, H Fedorow, C H Rickert, M Gerlach, P Riederer, K L Doubl. Evidence for specific phases in the development of human neuromelanin. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 6. 2007-05-08. PMID:16604299. |
neuromelanin is a dark-coloured pigment which forms in the dopamine neurons of the human midbrain. |
2007-05-08 |
2023-08-12 |
human |
| Loredana D'Este, Arianna Casini, Stefano Puglisi-Allegra, Simona Cabib, Tindaro G Rend. Comparative immunohistochemical study of the dopaminergic systems in two inbred mouse strains (C57BL/6J and DBA/2J). Journal of chemical neuroanatomy. vol 33. issue 2. 2007-05-08. PMID:17276033. |
the number of dopamine transporter (dat), vesicular monoamine transporter of type 2 (vmt) and tyrosine hydroxylase (th) immunoreactive cell bodies was significantly higher in the midbrain of dba mice than in c57 mice (on average +21.5%, p<0.001 in a10: +9.4% in a9, p<0.05: and +5.9% in a8, p<0.1). |
2007-05-08 |
2023-08-12 |
mouse |
| Li-Ping Liang, Jie Huang, Ruth Fulton, Brian J Day, Manisha Pate. An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 16. 2007-05-07. PMID:17442816. |
aeol11207 administered either by subcutaneous or oral routes protected against mptp-induced dopamine depletion in the striatum as well as dopaminergic neuronal loss, glutathione depletion, lipid peroxidation, and 3-nt formation in the ventral midbrain. |
2007-05-07 |
2023-08-12 |
mouse |
| Kurt Rasmussen, Mei-Ann Hsu, Yili Yan. The orexin-1 receptor antagonist SB-334867 blocks the effects of antipsychotics on the activity of A9 and A10 dopamine neurons: implications for antipsychotic therapy. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 4. 2007-05-01. PMID:17063151. |
recordings from midbrain dopamine neurons showed that acute administration of sb-334867 alone did not alter the number of spontaneously active a9 or a10 cells, but did reverse: (1) the increase in the number of spontaneously active a9 and/or a10 dopamine cells caused by the acute administration of haloperidol (1 mg/kg, subcutaneous) or olanzapine (10 mg/kg, s.c.) and (2) the decrease in the number of spontaneously active a9 and/or a10 dopamine cells caused by the chronic administration of haloperidol (1 mg/kg/day x 21 days, s.c.) or olanzapine (10 mg/kg/day x 21 days, s.c.). |
2007-05-01 |
2023-08-12 |
rat |
| Erica L Unger, Tessy Paul, Laura E Murray-Kolb, Barbara Felt, Byron C Jones, John L Bear. Early iron deficiency alters sensorimotor development and brain monoamines in rats. The Journal of nutrition. vol 137. issue 1. 2007-04-10. PMID:17182811. |
postnatal iron deficiency reduced striatal and ventral midbrain iron as well as cellular dopamine levels in prefrontal cortex and striatum at p21. |
2007-04-10 |
2023-08-12 |
human |
| Sara af Bjerkén, Heather A Boger, Matthew Nelson, Barry J Hoffer, Ann-Charlotte Granholm, Ingrid Strömber. Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures. Brain research. vol 1133. issue 1. 2007-04-05. PMID:17184739. |
glial cell line-derived neurotrophic factor (gdnf) is potent for survival and promotion of nerve fibers from midbrain dopamine neurons. |
2007-04-05 |
2023-08-12 |
mouse |
| Sara af Bjerkén, Heather A Boger, Matthew Nelson, Barry J Hoffer, Ann-Charlotte Granholm, Ingrid Strömber. Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures. Brain research. vol 1133. issue 1. 2007-04-05. PMID:17184739. |
in conclusion, cultured midbrain dopamine neurons survive in the absence of gdnf, and the addition of gdnf improved dopamine nerve fiber formation - possibly as an indirect effect of astrocytic stimulation. |
2007-04-05 |
2023-08-12 |
mouse |
| Gregory D Lyng, Abigail Snyder-Keller, Richard F Seega. Dopaminergic development of prenatal ventral mesencephalon and striatum in organotypic co-cultures. Brain research. vol 1133. issue 1. 2007-04-05. PMID:17196555. |
using organotypic co-cultures of rat embryonic day 14 (e14) ventral mesencephalon (vm) and e21 striatum, we have described the developmental changes in (i) dopamine (da) neurochemistry; (ii) numbers of da neurons; and (iii) protein expression of tyrosine hydroxylase (th), da transporter (dat), and glutamic acid decarboxylase (gad 65/67), over 17 days in vitro (div). |
2007-04-05 |
2023-08-12 |
rat |