| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Krysiak, E Obuchowicz, Z S Herma. Interactions between the neuropeptide Y system and the hypothalamic-pituitary-adrenal axis. European journal of endocrinology. vol 140. issue 2. 1999-03-29. PMID:10069655. |
we also describe the effects of glucocorticosteroids on the npy system in the hypothalamus, including interactions between glucocorticosteroids and insulin. |
1999-03-29 |
2023-08-12 |
Not clear |
| B Jeanrenaud, I Cusin, F Rohner-Jeanrenau. [From Claude Bernard to the regulatory system between the hypothalamus and the periphery: implications for homeostasis of body weight and obesity]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 192. issue 5. 1999-01-28. PMID:9871796. |
released leptin, acting within the hypothalamus, decreases hypothalamic npy levels (probably those of other hypothalamic neuropeptides as well), food intake, insulinemia, insulin sensitivity of white adipose tissue, while increasing that of muscles. |
1999-01-28 |
2023-08-12 |
rat |
| H Yoshitomi, K Yamazaki, S Abe, I Tanak. Differential regulation of mouse uncoupling proteins among brown adipose tissue, white adipose tissue, and skeletal muscle in chronic beta 3 adrenergic receptor agonist treatment. Biochemical and biophysical research communications. vol 253. issue 1. 1999-01-13. PMID:9875224. |
it has been thought that the ucp1 and ucp3 mrna expressions in the bat and wat are mainly controlled by the hypothalamus via the sympathetic nervous system, while the levels of insulin, ffa or both may play important roles in the control of the ucp2 and ucp3 mrna expressions in the skeletal muscle an heart. |
1999-01-13 |
2023-08-12 |
mouse |
| T KUZUY. [Regulation of insulin secretion by the central nervous system. II. The role of the hypothalamus and the pituitary gland upon insulin secretion]. Japanese journal of medical science & biology. vol 51. 1998-11-01. PMID:13927726. |
the role of the hypothalamus and the pituitary gland upon insulin secretion]. |
1998-11-01 |
2023-08-12 |
Not clear |
| W A Banks, A J Kasti. Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin. Peptides. vol 19. issue 5. 1998-09-28. PMID:9663454. |
for insulin, the areas of highest uptake were the pons-medulla and the hypothalamus, whereas three regions (midbrain, thalamus, and occipital cortex) did not have a measurable ki. |
1998-09-28 |
2023-08-12 |
mouse |
| R Serino, Y Ueta, M Tokunaga, Y Hara, M Nomura, N Kabashima, I Shibuya, Y Hattori, H Yamashit. Upregulation of hypothalamic nitric oxide synthase gene expression in streptozotocin-induced diabetic rats. Diabetologia. vol 41. issue 6. 1998-09-11. PMID:9662044. |
although osmotic stimuli cause an increase in nitric oxide synthase (nos) activity as well as synthesis of avp and oxytocin in the paraventricular (pvn) and supraoptic nuclei (son), it is not known whether nos activity in the hypothalamus changes in the diabetic patients who have plasma hyperosmolality with hyperglycaemia caused by insulin deficiency. |
1998-09-11 |
2023-08-12 |
rat |
| A K Panicker, G N Wad. Insulin-induced repartitioning of metabolic fuels inhibits hamster estrous behavior: role of area postrema. The American journal of physiology. vol 274. issue 4. 1998-06-02. PMID:9575974. |
insulin treatments also caused changes in the number of detectable estrogen receptor immunoreactive cells in the hypothalamus and preoptic area. |
1998-06-02 |
2023-08-12 |
Not clear |
| H Isotani, K Kameoka, K Furukaw. Daily profile of serum leptin in Prader-Willi syndrome complicated by diabetes mellitus--a case report. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 29. issue 12. 1998-03-17. PMID:9497896. |
in order to study whether there is a defective action of leptin on the hypothalamus in p-w syndrome, we have measured leptin and insulin twice during the daily profile of blood glucose, comparing the results with the recent reports. |
1998-03-17 |
2023-08-12 |
Not clear |
| D F Hopkins, G William. Insulin receptors are widely distributed in human brain and bind human and porcine insulin with equal affinity. Diabetic medicine : a journal of the British Diabetic Association. vol 14. issue 12. 1998-02-26. PMID:9455932. |
we have studied the binding of 125i labelled human insulin, and its displacement by unlabelled human and porcine insulin, in homogenates prepared from human hypothalamus, cerebral cortex and cerebellum obtained post-mortem from eight non-diabetic subjects. |
1998-02-26 |
2023-08-12 |
human |
| G van Dijk, C de Groote, M Chavez, Y van der Werf, A B Steffens, J H Strubb. Insulin in the arcuate nucleus of the hypothalamus reduces fat consumption in rats. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449423. |
insulin in the arcuate nucleus of the hypothalamus reduces fat consumption in rats. |
1998-02-24 |
2023-08-12 |
rat |
| G van Dijk, C de Groote, M Chavez, Y van der Werf, A B Steffens, J H Strubb. Insulin in the arcuate nucleus of the hypothalamus reduces fat consumption in rats. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449423. |
data are accumulating that insulin acting in the central nervous system is a physiological regulator of food intake and body weight, presumably via its effect in the hypothalamus. |
1998-02-24 |
2023-08-12 |
rat |
| G van Dijk, C de Groote, M Chavez, Y van der Werf, A B Steffens, J H Strubb. Insulin in the arcuate nucleus of the hypothalamus reduces fat consumption in rats. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449423. |
at the beginning of the dark period, rats received local bilateral infusions of 4 microu of insulin or vehicle during 34 min into the arcuate (arc) or paraventricular (pvn) nucleus of the hypothalamus. |
1998-02-24 |
2023-08-12 |
rat |
| B G Hoebe. Neuroscience and appetitive behavior research: 25 years. Appetite. vol 29. issue 2. 1998-01-22. PMID:9344422. |
highlights in six areas are summarized to illustrate progress during the 25 years of the columbia appetitive behavior seminar: (1) discovery of angiotensin and aldosterone in the control of thirst and salt appetite; (2) electrophysiological decoding of chemoreceptive information in the brain; (3) a new foundation in the hypothalamus built on peptides, such as neuropeptide y and galanin, interacting with monoamines and steroids in the control of appetite for macronutrients; (4) discovery of numerous peptides that mediate and integrate satiety, such as cholecystokinin, insulin, leptin and enterostatin, and other systems that suppress eating during illness; (5) better understanding of appetite suppressant drugs, and (6) exploration of a circuit that translates hypothalamic signals into behavioral action through connections to brainstem reflex arcs and forebrain instrumental response systems. |
1998-01-22 |
2023-08-12 |
Not clear |
| R Parikh, J L Mark. Metabolic and orexigenic effects of intracerebroventricular neuropeptide Y are attenuated by food deprivation. Journal of neuroendocrinology. vol 9. issue 10. 1997-12-23. PMID:9355048. |
administration of neuropeptide y (npy) into the hypothalamus or cerebral ventricles has been shown to increase food intake, the secretion of hormones such as insulin, glucagon and corticosterone and to alter the metabolism of carbohydrate and lipids. |
1997-12-23 |
2023-08-12 |
rat |
| J Agata, A Masuda, M Takada, K Higashiura, H Murakami, Y Miyazaki, K Shimamot. High plasma immunoreactive leptin level in essential hypertension. American journal of hypertension. vol 10. issue 10 Pt 1. 1997-12-12. PMID:9370390. |
recently it was reported that insulin resistance was related to an elevated plasma level of leptin, which is an adipocyte-specific ob gene product and which plays a role in food intake suppression, thermogenesis, and energy expenditure through the activation of the hypothalamus. |
1997-12-12 |
2023-08-12 |
human |
| K Gerozissis, M Orosco, C Rouch, S Nicolaidi. Insulin responses to a fat meal in hypothalamic microdialysates and plasma. Physiology & behavior. vol 62. issue 4. 1997-10-28. PMID:9284495. |
in the present study, we have attempted to assess the profile of medial hypothalamus (vmph-pvn) extracellular insulin and peripheral insulin before and after a fat meal (lard). |
1997-10-28 |
2023-08-12 |
rat |
| J W Unger, W Lang. Insulin receptors in the pituitary gland: morphological evidence for influence on opioid peptide-synthesizing cells. Cell and tissue research. vol 288. issue 3. 1997-08-15. PMID:9134860. |
the relationship between beta-endorphin and insulin receptors provides further evidence for the hypothesis that peripheral insulin acts as a regulatory hormone in the control of body energy homeostasis via various steps of the neuroendocrine axis, including opioid peptides in the hypothalamus and pituitary known to play an important role in the regulation of feeding behaviour. |
1997-08-15 |
2023-08-12 |
rat |
| M W Schwart. Regulation of appetite and body weight. Hospital practice (1995). vol 32. issue 7. 1997-08-11. PMID:9227661. |
hormones such as leptin and insulin participate in this system, which links changes in body fat content to appropriate compensatory responses in the hypothalamus. |
1997-08-11 |
2023-08-12 |
Not clear |
| C Tang, A Akabayashi, A Manitiu, S F Leibowit. Hypothalamic galanin gene expression and peptide levels in relation to circulating insulin: possible role in energy balance. Neuroendocrinology. vol 65. issue 4. 1997-07-18. PMID:9142998. |
this investigation examined whether circulating insulin, in turn, has impact on hypothalamic gal production, gal mrna and peptide concentrations in the hypothalamus. |
1997-07-18 |
2023-08-12 |
human |
| J L Marks, K Wait. Intracerebroventricular neuropeptide Y acutely influences glucose metabolism and insulin sensitivity in the rat. Journal of neuroendocrinology. vol 9. issue 2. 1997-05-09. PMID:9041362. |
acute administration of neuropeptide y(npy) into the hypothalamus and third cerebral ventricle (icv) increases respiratory quotient, reduces energy expenditure and increases circulating, insulin, glucagon and corticosterone. |
1997-05-09 |
2023-08-12 |
rat |