| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M F McCart. Longevity effect of chromium picolinate--'rejuvenation' of hypothalamic function? Medical hypotheses. vol 43. issue 4. 1995-03-02. PMID:7838011. |
conversely, promoting brain insulin activity with chromium picolinate may help to maintain the hypothalamus in a more functionally youthful state; increased hypothalamic catecholamine activity, sensitization of insulin-responsive central mechanisms regulating appetite and thermogenesis, and perhaps trophic effects on brain neurons may play a role in this regard. |
1995-03-02 |
2023-08-12 |
Not clear |
| G van Dijk, A E Bottone, J H Strubbe, A B Steffen. Hormonal and metabolic effects of paraventricular hypothalamic administration of neuropeptide Y during rest and feeding. Brain research. vol 660. issue 1. 1995-02-21. PMID:7828007. |
to investigate the role of neuropeptide y (npy) in the paraventricular nucleus of the hypothalamus (pvn) in the regulation of autonomic outflow, hormonal (plasma insulin and catecholamines), metabolic (blood glucose and plasma free fatty acids) and cardiovascular (heart rate and main arterial pressure) indices were measured before, during, and after bilateral infusion of npy (1.0, 0.2, 0.04 micrograms in 1 microliter synthetic csf) into the pvn of conscious resting rats. |
1995-02-21 |
2023-08-12 |
rat |
| J F Bruno, Y Xu, J Song, M Berelowit. Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat. Endocrinology. vol 135. issue 5. 1994-12-16. PMID:7956902. |
in contrast to the effect of fd, sstr5 mrna levels were reduced 70% in the pituitary and 30% in the hypothalamus of stz diabetic rats, with complete restoration by insulin. |
1994-12-16 |
2023-08-12 |
rat |
| M Jhanwar-Uniyal, B Moorjani, A H Kah. Indications of pre- and post-synaptic 5-HT1A receptor interactions in feeding behavior and neuroendocrine regulation. Brain research. vol 646. issue 2. 1994-09-23. PMID:8069671. |
in the biochemical study, radioligand binding techniques were used to assess 5-ht1a receptor density in the hypothalamus, as well as the relationship between 5-ht1a receptors and circulating levels of insulin and glucose. |
1994-09-23 |
2023-08-12 |
rat |
| A Oohara, H Yoshimatsu, M Kurokawa, R Oishi, K Saeki, T Sakat. Neuronal glucoprivation enhances hypothalamic histamine turnover in rats. Journal of neurochemistry. vol 63. issue 2. 1994-08-12. PMID:8035192. |
histamine (ha) turnover in the rat hypothalamus following insufficient energy supply due to glucoprivation was examined after administration of insulin or 2-deoxy-d-glucose (2-dg). |
1994-08-12 |
2023-08-12 |
rat |
| J P Porte. Effect of intrahypothalamic insulin on sympathetic nervous function in rats drinking a high-sucrose solution. The American journal of physiology. vol 266. issue 5 Pt 2. 1994-07-05. PMID:8203621. |
however, direct injection of insulin into the hypothalamus of anesthetized rats produces sympatho-inhibition. |
1994-07-05 |
2023-08-12 |
rat |
| P L Selvais, D M Maite. [Neuroendocrine regulation of eating behavior]. Acta gastro-enterologica Belgica. vol 56. issue 5-6. 1994-04-28. PMID:8140849. |
digestive or metabolic inputs are conveyed to the hypothalamus by endocrine and neuroendocrine pathways (insulin, cholecystokinin). |
1994-04-28 |
2023-08-12 |
Not clear |
| Iu M Kolesnyk, A V Abramo. [Hypothalamic mechanisms of neurohormone regulation of the endocrine part of the pancreas]. Ukrainskii biokhimicheskii zhurnal (1978). vol 65. issue 3. 1994-02-18. PMID:7904782. |
adaptation to hypoxia corrected impaired hormone balance and state of langerhans islets (beta-cells destruction process inhibition, insulin biosynthesis stimulation, glucagon and somatostatin secretion decrease) under diabetes mellitus, hypothalamus neurohormones participating in this process. |
1994-02-18 |
2023-08-12 |
Not clear |
| J P Wilding, S G Gilbey, P D Lambert, M A Ghatei, S R Bloo. Increases in neuropeptide Y content and gene expression in the hypothalamus of rats treated with dexamethasone are prevented by insulin. Neuroendocrinology. vol 57. issue 4. 1993-10-04. PMID:8367026. |
increases in neuropeptide y content and gene expression in the hypothalamus of rats treated with dexamethasone are prevented by insulin. |
1993-10-04 |
2023-08-12 |
rat |
| J P Wilding, S G Gilbey, P D Lambert, M A Ghatei, S R Bloo. Increases in neuropeptide Y content and gene expression in the hypothalamus of rats treated with dexamethasone are prevented by insulin. Neuroendocrinology. vol 57. issue 4. 1993-10-04. PMID:8367026. |
we measured npy content in individual hypothalamic nuclei, and hypothalamic npy mrna by northern blotting in whole hypothalamus in rats treated with dexamethasone (0.4 mg/kg/day) and dexamethasone plus insulin (60 u/kg/day), compared to controls. |
1993-10-04 |
2023-08-12 |
rat |
| J L Marks, K Waite, M L. Effects of streptozotocin-induced diabetes mellitus and insulin treatment on neuropeptide Y mRNA in the rat hypothalamus. Diabetologia. vol 36. issue 6. 1993-08-26. PMID:8335171. |
effects of streptozotocin-induced diabetes mellitus and insulin treatment on neuropeptide y mrna in the rat hypothalamus. |
1993-08-26 |
2023-08-12 |
rat |
| b' B Jamnicky, D M\\xc3\\xbcck-Seler, M Slijepcevi\\xc4\\x8. Favourable effect of tryptophan/insulin treatment on serotoninergic imbalance in alloxan diabetic rats. Comparative biochemistry and physiology. Comparative physiology. vol 105. issue 2. 1993-08-19. PMID:7687210.' |
the effects of insulin and/or tryptophan (try) administration on try, serotonin (5-ht), 5-hydroxyindolacetic acid (5-hiaa) in raphe nuclei and hypothalamus and serum levels of large neutral amino acids [try, valine, isoleucine, leucine, tyrosine and phenylalanine, (lnaa)] was investigated in diabetic rats. |
1993-08-19 |
2023-08-12 |
rat |
| D G Baskin, E P Gierke, B J Wilcox, A M Matsumoto, M W Schwart. Food intake and estradiol effects on insulin binding in brain and liver. Physiology & behavior. vol 53. issue 4. 1993-07-12. PMID:8511182. |
specific binding of insulin to liver and hypothalamus slices was measured by quantitative film autoradiography. |
1993-07-12 |
2023-08-12 |
rat |
| D G Baskin, E P Gierke, B J Wilcox, A M Matsumoto, M W Schwart. Food intake and estradiol effects on insulin binding in brain and liver. Physiology & behavior. vol 53. issue 4. 1993-07-12. PMID:8511182. |
insulin binding in the dorsomedial, ventromedial, and arcuate nuclei of the hypothalamus was unchanged by food intake or estradiol, however. |
1993-07-12 |
2023-08-12 |
rat |
| D G Baskin, E P Gierke, B J Wilcox, A M Matsumoto, M W Schwart. Food intake and estradiol effects on insulin binding in brain and liver. Physiology & behavior. vol 53. issue 4. 1993-07-12. PMID:8511182. |
thus, altered insulin binding in the arcuate, ventromedial, or dorsomedial nuclei of the hypothalamus is probably not involved in the effects of insulin or estradiol on food intake. |
1993-07-12 |
2023-08-12 |
rat |
| L A Miller, L Z Cheng, R W. Inhibition of epidermal growth factor-like growth factor secretion in tracheobronchial epithelial cells by vitamin A. Cancer research. vol 53. issue 11. 1993-06-21. PMID:8495415. |
retinol and its derivatives have little growth-stimulatory effect on tbe cells that are maintained in primary culture in a serum-free medium supplemented with 6 hormonal supplements: insulin, transferrin, epidermal growth factor (egf), hydrocortisone, cholera toxin, and bovine hypothalamus extract. |
1993-06-21 |
2023-08-12 |
human |
| I Ahmed, T J Lauteri. Intracerebroventricular injection of insulin or glucose alters insulin-like growth factor II (IGF-II) concentrations in specific hypothalamic nuclei. Brain research. vol 595. issue 2. 1993-01-26. PMID:1467969. |
results show that insulin which reaches the brain can alter igf-ii levels in specific regions of the hypothalamus and suggests a possible role for igf-ii in insulin mediated changes in metabolism or hypothalamic hormone secretion. |
1993-01-26 |
2023-08-11 |
rat |
| M C Gelato, D Alexander, K Mars. Differential tissue regulation of insulin-like growth factor binding proteins in experimental diabetes mellitus in the rat. Diabetes. vol 41. issue 12. 1992-12-28. PMID:1280236. |
in hypothalamus and cerebral cortex tissue, bands at 30,000 and 25,000 m(r) were noted, and neither was altered by diabetes or insulin treatment. |
1992-12-28 |
2023-08-11 |
rat |
| M W Schwartz, A J Sipols, J L Marks, G Sanacora, J D White, A Scheurink, S E Kahn, D G Baskin, S C Woods, D P Figlewic. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology. vol 130. issue 6. 1992-07-06. PMID:1597158. |
fasting, therefore, increases npy biosynthesis along an arcuate nucleus-pvn pathway in the hypothalamus via a mechanism dependent on low insulin levels. |
1992-07-06 |
2023-08-11 |
rat |
| H Lach, Z Srebro, J Surowia. Changes in RNA content of the hypothalamus of mice following insulin administration. Folia biologica. vol 39. issue 1-4. 1992-06-16. PMID:1725978. |
changes in rna content of the hypothalamus of mice following insulin administration. |
1992-06-16 |
2023-08-11 |
mouse |