| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Marks, J Maddison, C J Eastma. Subcellular localization of rat brain insulin binding sites. Journal of neurochemistry. vol 50. issue 3. 1988-03-23. PMID:2828547. |
insulin binding to the p2 was compared with plasma membrane fractions in seven brain regions, and the results demonstrated the same close relationship between insulin binding and plasma membrane content in all regions except hypothalamus. |
1988-03-23 |
2023-08-11 |
rat |
| J L Marks, J Maddison, C J Eastma. Subcellular localization of rat brain insulin binding sites. Journal of neurochemistry. vol 50. issue 3. 1988-03-23. PMID:2828547. |
plasma membrane insulin binding was well represented by the binding on p2 membranes in all regions except hypothalamus and brainstem. |
1988-03-23 |
2023-08-11 |
rat |
| F Rohner-Jeanrenaud, B Jeanrenau. [Interactions between the central nervous system, the endocrine pancreas and metabolism]. Annales d'endocrinologie. vol 48. issue 5. 1988-03-15. PMID:3324925. |
a peptide of around 1'000 daltons extracted from the rat hypothalamus and having insulin secretion promoting activity could possibly be an insulin-releasing factor since it is present not only in the hypothalamus but also in the plasma. |
1988-03-15 |
2023-08-11 |
rat |
| M Manin, M Mizrahi, P Vye, M Balage, J Grizar. The influence of acute hyperinsulinemia on the insulin-related material in brain, testis, liver, and kidney. Metabolism: clinical and experimental. vol 36. issue 11. 1987-12-09. PMID:3312936. |
insulin injection had no effect on the insulin-related material in most areas of brain (cerebral cortex, olfactory bulbs, and medial hypothalamus) and the cerebrospinal fluid; lateral hypothalamus was an exception and paradoxically exhibited a decrease of this material. |
1987-12-09 |
2023-08-11 |
rat |
| R J Ross, A Grossman, P S Davies, M O Savage, G M Besse. Stilboestrol pretreatment of children with short stature does not affect the growth hormone response to growth hormone-releasing hormone. Clinical endocrinology. vol 27. issue 2. 1987-11-30. PMID:3117450. |
to examine whether this effect is mediated through the hypothalamus or the pituitary we performed insulin tolerance and gh-releasing hormone (ghrh) tests with and without oestrogen priming in a group of 14 short children. |
1987-11-30 |
2023-08-11 |
Not clear |
| R J Ross, A Grossman, P S Davies, M O Savage, G M Besse. Stilboestrol pretreatment of children with short stature does not affect the growth hormone response to growth hormone-releasing hormone. Clinical endocrinology. vol 27. issue 2. 1987-11-30. PMID:3117450. |
we conclude stilboestrol priming acts through the hypothalamus presumably by increasing endogenous ghrh release, and that short children with a subnormal gh response to insulin hypoglycaemia show a greater response to ghrh; this suggests the presence of a hypothalamic cause for their decreased gh secretion. |
1987-11-30 |
2023-08-11 |
Not clear |
| J M Peinado, R D Myer. Norepinephrine release from PVN and lateral hypothalamus during perfusion with 2-DG or insulin in the sated and fasted rat. Pharmacology, biochemistry, and behavior. vol 27. issue 4. 1987-10-29. PMID:3310022. |
both insulin and 2-deoxy-d-glucose (2-dg) when given systemically to the rat modify the activity of noradrenergic systems in different regions of the animal's hypothalamus. |
1987-10-29 |
2023-08-11 |
rat |
| J M Peinado, R D Myer. Norepinephrine release from PVN and lateral hypothalamus during perfusion with 2-DG or insulin in the sated and fasted rat. Pharmacology, biochemistry, and behavior. vol 27. issue 4. 1987-10-29. PMID:3310022. |
the purpose of the present investigation was to ascertain whether the nutritional status of the animal would serve to influence the pattern of efflux of norepinephrine (ne) from sites in the hypothalamus perfused with either 2-dg or insulin. |
1987-10-29 |
2023-08-11 |
rat |
| T L Riss, D A Sirbask. Growth and continuous passage of COMMA-D mouse mammary epithelial cells in hormonally defined serum-free medium. Cancer research. vol 47. issue 14. 1987-08-20. PMID:3297308. |
comma-d cells seeded in basal medium supplemented with insulin, transferrin, and selenous acid have been used to detect mitogenic activity present in extracts of hypothalamus, uterus, and pituitary. |
1987-08-20 |
2023-08-11 |
mouse |
| T Karashima, K Kato, H Nawata, S Ikuyama, H Ibayashi, H Nakagaki, K Kitamur. Postoperative plasma GH levels and restoration of GH dynamics in acromegalic patients surgically treated by the transsphenoidal approach. Clinical endocrinology. vol 25. issue 2. 1987-02-05. PMID:3791660. |
trh, lhrh and bromocriptine tests, which act directly on the pituitary somatotroph, and the oral glucose tolerance test (ogtt) and insulin tolerance test (itt), which act via hypothalamus, were carried out pre- and post-operatively. |
1987-02-05 |
2023-08-11 |
Not clear |
| K J Anan. The stress response to surgical trauma: from physiological basis to therapeutic implications. Progress in food & nutrition science. vol 10. issue 1-2. 1987-01-21. PMID:3097757. |
the response to surgical injury is mediated through the hypothalamus and is characterised by the release of catecholamines, glucocorticoids, growth hormone and glucagon; the suppression of insulin secretion and changes in other endocrine systems. |
1987-01-21 |
2023-08-11 |
Not clear |
| D Jezová, R Kvetnanský, K Kovács, Z Oprsalová, M Vigas, G B Makar. Insulin-induced hypoglycemia activates the release of adrenocorticotropin predominantly via central and propranolol insensitive mechanisms. Endocrinology. vol 120. issue 1. 1987-01-20. PMID:3023036. |
in rats 6-7 days after lesions of the medial basal hypothalamus (mbh), the rise of acth during insulin hypoglycemia was markedly inhibited and corticosterone levels were significantly reduced. |
1987-01-20 |
2023-08-11 |
rat |
| J Knudtzo. Effects of pro-opiomelanocortin-derived peptides on plasma levels of glucagon, insulin and glucose. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 9. 1987-01-08. PMID:3023222. |
pomc-derived peptides have been demonstrated in many tissues, including the hypothalamus and the endocrine pancreas, which play important roles in the control of plasma levels of glucagon, insulin and glucose. |
1987-01-08 |
2023-08-11 |
Not clear |
| J Knudtzo. Effects of pro-opiomelanocortin-derived peptides on plasma levels of glucagon, insulin and glucose. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 18. issue 9. 1987-01-08. PMID:3023222. |
this article reviews the present knowledge concerning in vitro and in vivo effects of pomc-derived peptides on glucagon, insulin and glucose levels involving several possible mechanisms: direct effects on the endocrine pancreas (including endocrine, paracrine and peptidergic regulation) and glucose production, and indirect effects involving the hypothalamus, the autonomic nervous system and the adrenal gland. |
1987-01-08 |
2023-08-11 |
Not clear |
| E S Corp, S C Woods, D Porte, D M Dorsa, D P Figlewicz, D G Baski. Localization of 125I-insulin binding sites in the rat hypothalamus by quantitative autoradiography. Neuroscience letters. vol 70. issue 1. 1986-12-17. PMID:3534636. |
the results are consistent with the hypothesis that insulin modulates the neural regulation of feeding by acting at sites in the hypothalamus. |
1986-12-17 |
2023-08-11 |
rat |
| D P Figlewicz, H Ikeda, T R Hunt, L J Stein, D M Dorsa, S C Woods, D Port. Brain insulin binding is decreased in Wistar Kyoto rats carrying the 'fa' gene. Peptides. vol 7. issue 1. 1986-07-14. PMID:3714533. |
in the present study, we measured insulin binding in membranes prepared from the olfactory bulb, cerebral cortex, and hypothalamus of control (fa/fa) wistar kyoto rats; "fatty" (fa/fa) wistar kyoto rats; and phenotypically lean (fa/?) |
1986-07-14 |
2023-08-11 |
rat |
| R Wu, M M W. Effects of retinoids on human bronchial epithelial cells: differential regulation of hyaluronate synthesis and keratin protein synthesis. Journal of cellular physiology. vol 127. issue 1. 1986-05-12. PMID:2420810. |
this serum-free medium, which was developed for the long-term cultivation of protease-dissociated hbe cells, consists of ham's f12 nutrient medium supplemented with insulin, transferrin, epidermal growth factor, hydrocortisone, cholera toxin, and bovine hypothalamus extract. |
1986-05-12 |
2023-08-11 |
human |
| P Rampa. [Mechanisms of the control of appetite]. Presse medicale (Paris, France : 1983). vol 15. issue 1. 1986-03-10. PMID:2868455. |
insulin might be the signal informing the hypothalamus on body fat mass. |
1986-03-10 |
2023-08-11 |
human |
| V Locatelli, F Petraglia, N Tirloni, E E Mülle. Beta-endorphin concentrations in the hypothalamus, pituitary and plasma of streptozotocin-diabetic rats with and without insulin substitution therapy. Life sciences. vol 38. issue 4. 1986-02-26. PMID:2935694. |
beta-endorphin concentrations in the hypothalamus, pituitary and plasma of streptozotocin-diabetic rats with and without insulin substitution therapy. |
1986-02-26 |
2023-08-11 |
rat |
| V Locatelli, F Petraglia, N Tirloni, E E Mülle. Beta-endorphin concentrations in the hypothalamus, pituitary and plasma of streptozotocin-diabetic rats with and without insulin substitution therapy. Life sciences. vol 38. issue 4. 1986-02-26. PMID:2935694. |
these results indicate that the lack of insulin may affect beta-end synthesis in the hypothalamus and nil. |
1986-02-26 |
2023-08-11 |
rat |