| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Wu, E Nolan, C Turne. Expression of tracheal differentiated functions in serum-free hormone-supplemented medium. Journal of cellular physiology. vol 125. issue 2. 1985-11-22. PMID:4055904. |
the medium is ham's f-12 supplemented with insulin, epidermal growth factor, transferrin, hydrocortisone, cholera toxin, bovine hypothalamus extract, and vitamin a. |
1985-11-22 |
2023-08-11 |
cattle |
| V D Tenedieva, O G Arestov, L V Mikrikova, E B Sirovskiĭ, B A Kadashe. [Regulation of carbohydrate metabolism in patients with tumors of the sellar-diencephalic area before and after surgery]. Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko. issue 4. 1985-11-15. PMID:2864771. |
dysfunction of the hypothalamus and endocrine cells of the pancreas in tumors of the sellar-diencephalic region gives grounds for applying postoperative corrective therapy including preparations of insulin and glucagon in patients with progressive signs of a brain lesion. |
1985-11-15 |
2023-08-11 |
Not clear |
| R Wu, J Yankaskas, E Cheng, M R Knowles, R Bouche. Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis. The American review of respiratory disease. vol 132. issue 2. 1985-09-12. PMID:3896079. |
ham's f12 medium supplemented with insulin (ins), transferrin (tf), epidermal growth factor (egf), hydrocortisone (hc), t3, cholera toxin (ct), and bovine hypothalamus extract (bhe) was developed for in vitro growth of human nasal epithelial (hne) cells. |
1985-09-12 |
2023-08-11 |
human |
| T Mori, K Nagai, M Hara, H Nakagaw. Time-dependent effect of insulin in suprachiasmatic nucleus on blood glucose. The American journal of physiology. vol 249. issue 1 Pt 2. 1985-08-13. PMID:2990242. |
studies were made on the effects of insulin (30 or 300 microu) injected into the suprachiasmatic nucleus (scn) of the hypothalamus on the plasma glucose and insulin concentrations in pentobarbital-anesthetized rats, which had been kept under 12:12 light-dark conditions. |
1985-08-13 |
2023-08-11 |
rat |
| J W Groelke, J J Coalson, J B Basema. Growth requirements of ferret tracheal epithelial cells in primary culture. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 179. issue 3. 1985-07-24. PMID:3889927. |
the growth factor constituents of the f12 medium included epidermal growth factor (25 ng/ml), insulin (1 microgram/ml), transferrin (10 micrograms/ml), hydrocortisone (18 ng/ml), hypothalamus extract (30-100 micrograms/ml), and conditioned medium from mouse 3t3 fibroblasts. |
1985-07-24 |
2023-08-11 |
mouse |
| D G Baskin, L J Stein, H Ikeda, S C Woods, D P Figlewicz, D Porte, M R Greenwood, D M Dors. Genetically obese Zucker rats have abnormally low brain insulin content. Life sciences. vol 36. issue 7. 1985-03-18. PMID:3881641. |
the concentration of immunoreactive insulin (iri) extracted from the olfactory bulb, hypothalamus, hippocampus, cerebral cortex, amygdala, midbrain, and hindbrain was significantly lower in obese (fa/fa) and heterozygous (fa/fa) zucker rats in comparison to lean (fa/fa) zucker rats. |
1985-03-18 |
2023-08-11 |
rat |
| H S Grunstein, D E James, L H Storlien, G A Smythe, E W Kraege. Hyperinsulinemia suppresses glucose utilization in specific brain regions: in vivo studies using the euglycemic clamp in the rat. Endocrinology. vol 116. issue 2. 1985-02-26. PMID:3967621. |
to determine whether insulin per se alters brain glucose metabolism, we measured glucose utilization rates, using the deoxyglucose method, in the medial basal hypothalamus, locus coeruleus, and motor cortex of conscious, unrestrained rats undergoing 2-h euglycemic clamps (blood glucose, 4.1 +/- 0.1 mmol/liter) at increasing insulin infusion rates. |
1985-02-26 |
2023-08-11 |
rat |
| H R Berthoud, T L Powle. Altered plasma insulin and glucose after obesity-producing bipiperidyl brain lesions. The American journal of physiology. vol 248. issue 1 Pt 2. 1985-02-25. PMID:3881985. |
bpm-treated animals with verified lesions of the medial portion of the solitary tract nucleus (nts) and the medial pole of the dorsal motor nucleus of the vagus (dmnx), as well as small lesions affecting the arcuate nucleus and basomedial portion of the ventromedial nucleus of the hypothalamus, showed the following characteristics: normal basal glycemia and insulinemia, exaggerated plasma insulin responses to oral or intravenous glucose and to oral saccharin, increased plasma glucose levels after oral glucose, unimpaired feeding to 2-deoxy-d-glucose challenge, decreased short-term intake of highly palatable food, and 36% more body fat at the end of the experiment. |
1985-02-25 |
2023-08-11 |
rat |
| A B Steffens, G Damsma, J van der Gugten, P G Luite. Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats. The American journal of physiology. vol 247. issue 6 Pt 1. 1985-01-24. PMID:6391199. |
circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats. |
1985-01-24 |
2023-08-12 |
rat |
| K Seto, H Saito, H Kaba, Y Sasaki, T Tsuda, M Kawakam. Influence of lesions in the limbic-hypothalamic system on insulin responses to daily repeated cold exposures in rabbits. Experimental and clinical endocrinology. vol 84. issue 1. 1984-11-19. PMID:6383848. |
the effects of lesions in the basal medial hypothalamus and limbic structures on the responses in plasma levels of insulin and glucose to daily repeated cold exposure in rabbits have been investigated. |
1984-11-19 |
2023-08-12 |
Not clear |
| T C Lee, R Wu, A R Brody, J C Barrett, P Netteshei. Growth and differentiation of hamster tracheal epithelial cells in culture. Experimental lung research. vol 6. issue 1. 1984-08-02. PMID:6734541. |
insulin, transferrin, hydrocortisone, epidermal growth factor, and an extract from bovine hypothalamus were used as supplements. |
1984-08-02 |
2023-08-12 |
mouse |
| F Rohner-Jeanrenaud, B Jeanrenau. [The central nervous system-endocrine pancreas axis]. Annales d'endocrinologie. vol 44. issue 4. 1984-03-27. PMID:6142677. |
hypothalamic factors present in the ventromedial or the ventrolateral hypothalamus have been shown to have insulin secretion promoting activity when administered in vivo or in vitro to donor rats. |
1984-03-27 |
2023-08-12 |
rat |
| A Dorn, A Rinne, H G Bernstein, H J Hahn, M Ziegle. Insulin and C-peptide in human brain neurons (insulin/C-peptide/brain peptides/immunohistochemistry/radioimmunoassay). Journal fur Hirnforschung. vol 24. issue 5. 1984-03-19. PMID:6363522. |
radioimmunoassay revealed that human brain contains insulin and c-peptide in concentrations much higher than the blood, the highest being in the hypothalamus. |
1984-03-19 |
2023-08-12 |
human |
| A F Kosenko, G P Gushinets, L A Kozhevnikov. [Participation of the hypothalamus and supraoptic-hypophyseal neurosecretory system in regulation of gastric secretion stimulated by insulin]. Fiziologicheskii zhurnal. vol 29. issue 5. 1984-01-07. PMID:6357863. |
[participation of the hypothalamus and supraoptic-hypophyseal neurosecretory system in regulation of gastric secretion stimulated by insulin]. |
1984-01-07 |
2023-08-12 |
Not clear |
| V G Shaliapina, N A Chemyrta. [Analysis of the mechanisms of refractivity of the pituitary-adrenal system in rat ontogeny]. Problemy endokrinologii. vol 29. issue 5. 1984-01-07. PMID:6685869. |
the chemical stimulants of the adrenal cortex (acth), of the pituitary (vasopressin) and of the hypothalamus (insulin) activate the peripheral and central components of the pas at varying age periods and to varying degree. |
1984-01-07 |
2023-08-12 |
rat |
| B A Gilchrest, R L Karassik, L M Wilkins, M A Vrabel, T Macia. Autocrine and paracrine growth stimulation of cells derived from human skin. Journal of cellular physiology. vol 117. issue 2. 1983-12-21. PMID:6630300. |
in m199 supplemented with epidermal growth factor, hydrocortisone, insulin, transferrin, triidothyronine, bovine serum albumin, and an extract of bovine hypothalamus, keratinocytes underwent approximately three to five cumulative population doublings (cpd) over a 7-day period. |
1983-12-21 |
2023-08-12 |
human |
| P Mineur, L Favre, A G Burger, M B Vallotto. [Endocrine function in old age (70 years and over)]. Schweizerische medizinische Wochenschrift. vol 113. issue 37. 1983-12-20. PMID:6635630. |
insulin, adh, catecholamines, lactotrope cells, trh and hypothalamus to steroids) due to either loss of receptors or modifications in post-receptor events. |
1983-12-20 |
2023-08-12 |
Not clear |
| D G Baskin, S C Woods, D B West, M van Houten, B I Posner, D M Dorsa, D Port. Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. Endocrinology. vol 113. issue 5. 1983-12-17. PMID:6354698. |
immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. |
1983-12-17 |
2023-08-12 |
rat |
| D G Baskin, S C Woods, D B West, M van Houten, B I Posner, D M Dorsa, D Port. Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. Endocrinology. vol 113. issue 5. 1983-12-17. PMID:6354698. |
to determine if insulin in cerebrospinal fluid (csf) may be a source of some insulin in brain tissue, [125i]iodoinsulin was stereotaxically injected into a lateral cerebral ventricle, and the uptake of radioactivity into periventricular hypothalamus was localized by both quantitative autoradiography of paraffin-embedded brain sections and by measuring the radioactivity present in microdissected brain regions. |
1983-12-17 |
2023-08-12 |
rat |
| D G Baskin, S C Woods, D B West, M van Houten, B I Posner, D M Dorsa, D Port. Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. Endocrinology. vol 113. issue 5. 1983-12-17. PMID:6354698. |
in brains that received lateral ventricular injections of labeled insulin, the concentration of radioactivity in the periventricular region of the hypothalamus, as revealed by autoradiographic grains, was significantly greater than that in the periventricular region of brains that received lateral ventricular injections of labeled insulin mixed with an equimolar excess of an unlabeled peptide (insulin, ribonuclease, or both together). |
1983-12-17 |
2023-08-12 |
rat |