| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Durand, O Berton, S Aguerre, L Edno, I Combourieu, P Mormède, F Chaoulof. Effects of repeated fluoxetine on anxiety-related behaviours, central serotonergic systems, and the corticotropic axis axis in SHR and WKY rats. Neuropharmacology. vol 38. issue 6. 1999-08-25. PMID:10465693. |
in both strains, the 10 mg/kg dose of fluoxetine decreased hypothalamus 5-ht and 5-hiaa levels, and reduced midbrain and/or hippocampus [3h]citalopram binding at 5-ht transporters, but did not affect [3h]8-hydroxy-2-(di-n-propylamino)tetralin binding at hippocampal 5-ht1a receptors. |
1999-08-25 |
2023-08-12 |
rat |
| M Durand, O Berton, S Aguerre, L Edno, I Combourieu, P Mormède, F Chaoulof. Effects of repeated fluoxetine on anxiety-related behaviours, central serotonergic systems, and the corticotropic axis axis in SHR and WKY rats. Neuropharmacology. vol 38. issue 6. 1999-08-25. PMID:10465693. |
however, the fluoxetine-elicited reduction in hippocampal 5-ht transporter binding was much more important in wky than in shr rats, this strain-dependent effect being associated in wky rats with a reduction in cortical [3h]ketanserin binding at 5-ht2a receptors. |
1999-08-25 |
2023-08-12 |
rat |
| L C Daws, G A Gerhardt, A Fraze. 5-HT1B antagonists modulate clearance of extracellular serotonin in rat hippocampus. Neuroscience letters. vol 266. issue 3. 1999-08-25. PMID:10465699. |
5-ht1b antagonists modulate clearance of extracellular serotonin in rat hippocampus. |
1999-08-25 |
2023-08-12 |
rat |
| L C Daws, G A Gerhardt, A Fraze. 5-HT1B antagonists modulate clearance of extracellular serotonin in rat hippocampus. Neuroscience letters. vol 266. issue 3. 1999-08-25. PMID:10465699. |
in vivo chronoamperometry was used to determine the effects of locally applied antagonists of the serotonin-1b (5-ht1b) receptor (cyanopindolol, 5-ht-moduline and methiothepin) on the clearance of 5-ht in the ca3 region of the dorsal hippocampus and the corpus callosum (a brain region devoid of serotonin transporters and 5-ht1b receptors) of the rat. |
1999-08-25 |
2023-08-12 |
rat |
| G F Molodtsov. [Sexual and interhemispheric differences in the involvement of serotonin from the hippocampus and amygdaloid body in the processing of new and repeatedly presented information in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 49. issue 3. 1999-08-18. PMID:10420552. |
[sexual and interhemispheric differences in the involvement of serotonin from the hippocampus and amygdaloid body in the processing of new and repeatedly presented information in rats]. |
1999-08-18 |
2023-08-12 |
rat |
| G F Molodtsov. [Sexual and interhemispheric differences in the involvement of serotonin from the hippocampus and amygdaloid body in the processing of new and repeatedly presented information in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 49. issue 3. 1999-08-18. PMID:10420552. |
it was found that hemispheric specificity of 5-ht metabolism in hippocampus and amygdala depended on sex and novelty of information. |
1999-08-18 |
2023-08-12 |
rat |
| G F Molodtsov. [Sexual and interhemispheric differences in the involvement of serotonin from the hippocampus and amygdaloid body in the processing of new and repeatedly presented information in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 49. issue 3. 1999-08-18. PMID:10420552. |
in male rats, the hippocampal level of 5-ht in response to the novel stimulus increased in the left hemisphere, and the 5-hiaa hippocampal level increased bilaterally in response to irrelevant stimulus. |
1999-08-18 |
2023-08-12 |
rat |
| G F Molodtsov. [Sexual and interhemispheric differences in the involvement of serotonin from the hippocampus and amygdaloid body in the processing of new and repeatedly presented information in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 49. issue 3. 1999-08-18. PMID:10420552. |
in females, an increase in 5-ht and/or 5-hiaa levels was observed only in the left hippocampus in response both to relevant and irrelevant stimuli. |
1999-08-18 |
2023-08-12 |
rat |
| D J Horrigan, C A Fuller, J M Horowit. Effects of hypergravic fields on serotonergic neuromodulation in the rat hippocampus. Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology. vol 4. issue 3. 1999-08-15. PMID:11541865. |
we conclude that the hippocampus contains surplus 5-ht receptors so that decreases in receptor density reported in receptor binding studies do not result in a decrease in modulatory capability. |
1999-08-15 |
2023-08-12 |
rat |
| A M Magariños, A Deslandes, B S McEwe. Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress. European journal of pharmacology. vol 371. issue 2-3. 1999-08-13. PMID:10357248. |
we used 5-ht-related antidepressants and a benzodiazepine in order to explore indirectly the role of serotonin and gaba(a)-benzodiazepine receptors in the stress-induced structural changes visualized by the golgi impregnation of the rat hippocampus. |
1999-08-13 |
2023-08-12 |
rat |
| A M Magariños, A Deslandes, B S McEwe. Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress. European journal of pharmacology. vol 371. issue 2-3. 1999-08-13. PMID:10357248. |
these findings suggest that the synaptic availability of 5-ht is involved in the mechanism leading to stress-induced dendritic remodeling and supports the idea that the hippocampal inhibitory gabaergic tone may play a regulatory role. |
1999-08-13 |
2023-08-12 |
rat |
| S P Park, F Lopez-Rodriguez, C L Wilson, N Maidment, Y Matsumoto, J Enge. In vivo microdialysis measures of extracellular serotonin in the rat hippocampus during sleep-wakefulness. Brain research. vol 833. issue 2. 1999-08-13. PMID:10375707. |
in vivo microdialysis measures of extracellular serotonin in the rat hippocampus during sleep-wakefulness. |
1999-08-13 |
2023-08-12 |
rat |
| S P Park, F Lopez-Rodriguez, C L Wilson, N Maidment, Y Matsumoto, J Enge. In vivo microdialysis measures of extracellular serotonin in the rat hippocampus during sleep-wakefulness. Brain research. vol 833. issue 2. 1999-08-13. PMID:10375707. |
we investigated extracellular 5-hydroxytryptamine (5-ht) levels in rat hippocampus during different stages of the sleep-waking cycle using in vivo microdialysis. |
1999-08-13 |
2023-08-12 |
rat |
| S P Park, F Lopez-Rodriguez, C L Wilson, N Maidment, Y Matsumoto, J Enge. In vivo microdialysis measures of extracellular serotonin in the rat hippocampus during sleep-wakefulness. Brain research. vol 833. issue 2. 1999-08-13. PMID:10375707. |
functional implications of as related-decreased 5-ht in the hippocampus are discussed. |
1999-08-13 |
2023-08-12 |
rat |
| T L Sills, A J Greenshaw, G B Baker, P J Fletche. The potentiating effect of sertraline and fluoxetine on amphetamine-induced locomotor activity is not mediated by serotonin. Psychopharmacology. vol 143. issue 4. 1999-08-05. PMID:10367561. |
both sertraline (5 mg/kg) and fluoxetine (5 mg/kg) produced an augmentation of amphetamine-induced hyperactivity that was unaltered by a serotonergic lesion of the median and dorsal raphe nuclei that resulted in a greater than 90% depletion of serotonin in hippocampus, striatum, and nucleus accumbens. |
1999-08-05 |
2023-08-12 |
rat |
| C Leranth, R P Verte. Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG. The Journal of comparative neurology. vol 410. issue 4. 1999-08-03. PMID:10398050. |
this could be a direct effect, because serotonin (5-ht) fibers terminate on a specific population of hippocampal interneurons. |
1999-08-03 |
2023-08-12 |
rat |
| C Leranth, R P Verte. Median raphe serotonergic innervation of medial septum/diagonal band of broca (MSDB) parvalbumin-containing neurons: possible involvement of the MSDB in the desynchronization of the hippocampal EEG. The Journal of comparative neurology. vol 410. issue 4. 1999-08-03. PMID:10398050. |
these observations indicate that 5-ht has a dual action on the activity of hippocampal principal cells: 1) an inhibition of the input sector by activation of hippocampal gaba neurons that terminate exclusively on apical dendrites of pyramidal cells, and 2) a disinhibition of the output sector of principal neurons. |
1999-08-03 |
2023-08-12 |
rat |
| K D Beck, V N Luin. Food deprivation modulates chronic stress effects on object recognition in male rats: role of monoamines and amino acids. Brain research. vol 830. issue 1. 1999-07-29. PMID:10350560. |
food deprived subjects had higher basal serotonin activity in prefrontal cortex and hippocampus as well as higher serum cort levels. |
1999-07-29 |
2023-08-12 |
human |
| I Shimizu, N Adachi, K Liu, B Lei, T Nagaro, T Ara. Sepsis facilitates brain serotonin activity and impairs learning ability in rats. Brain research. vol 830. issue 1. 1999-07-29. PMID:10350563. |
the brain concentration of serotonin was increased in the cerebral cortex, striatum, and hippocampus 48 h after the septic operation, but not after 24 h. the concentration of 5-hydroxyindoleacetic acid, a metabolite of serotonin, was increased in the above three regions both 24 and 48 h after the operation, but not in the hypothalamus. |
1999-07-29 |
2023-08-12 |
rat |
| A A Harrison, B J Everitt, T W Robbin. Central serotonin depletion impairs both the acquisition and performance of a symmetrically reinforced go/no-go conditional visual discrimination. Behavioural brain research. vol 100. issue 1-2. 1999-07-28. PMID:10212057. |
selective central 5-ht depletion (generally averaging more than 90% in neocortex, hippocampus and striatum) was induced by intracerebroventricular administration of the neurotoxin 5,7-dihydroxytryptamine (5,7-dht) following pretreatment with both a noradrenergic and dopaminergic re-uptake inhibitor. |
1999-07-28 |
2023-08-12 |
human |