| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Kita, M Takahashi, K Kubo, G C Wagner, T Nakashim. Hydroxyl radical formation following methamphetamine administration to rats. Pharmacology & toxicology. vol 85. issue 3. 1999-11-03. PMID:10522753. |
administration of neurotoxic doses of methamphetamine (8 mg/kg, intraperitoneally x 4 times, at 2 hr intervals) caused a significant decrease in dopamine and 3,4-dihydroxyphenylacetic acid and an increase in 3-methoxytyramine levels in the striatum along with a decrease in serotonin and 5-hydroxyindoleacetic acid levels in the striatum and hippocampus. |
1999-11-03 |
2023-08-12 |
rat |
| X M Li, K W Perry, D T Won. Difference in the in vivo influence of serotonin1A autoreceptors on serotonin release in prefrontal cortex and dorsal hippocampus of the same rat treated with fluoxetine. The Chinese journal of physiology. vol 42. issue 2. 1999-11-02. PMID:10513599. |
difference in the in vivo influence of serotonin1a autoreceptors on serotonin release in prefrontal cortex and dorsal hippocampus of the same rat treated with fluoxetine. |
1999-11-02 |
2023-08-12 |
rat |
| X M Li, K W Perry, D T Won. Difference in the in vivo influence of serotonin1A autoreceptors on serotonin release in prefrontal cortex and dorsal hippocampus of the same rat treated with fluoxetine. The Chinese journal of physiology. vol 42. issue 2. 1999-11-02. PMID:10513599. |
the investigational approach used in the present study was to detect extracellular 5-ht concentrations in two terminal areas, prefrontal cortex (pfc) and dorsal hippocampus (dhp), which are mainly innervated by the 5-ht neurons located in the drn and mrn respectively. |
1999-11-02 |
2023-08-12 |
rat |
| N Okad. [Mechanisms for formation and maintenance of synapses mediated by biogenic amines: pathogenesis and therapy of mental retardation and developmental disabilities by genetic and epigenetic factors]. Kaibogaku zasshi. Journal of anatomy. vol 74. issue 3. 1999-10-29. PMID:10577264. |
removing serotonin and acetylcholine for a week, at the maximum 58% of synapses are decreased in the hippocampus. |
1999-10-29 |
2023-08-12 |
Not clear |
| C Roberts, D F Boyd, D N Middlemiss, C Routledg. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471095. |
the effects of selective serotonin re-uptake inhibitor (ssri), paroxetine, and 5-ht1a, 5-ht1b and 5-ht1b/1d receptor antagonists on in vivo extracellular 5-ht levels in the guinea-pig frontal cortex and dorsal hippocampus were investigated using the technique of microdialysis. |
1999-10-25 |
2023-08-12 |
Not clear |
| C Roberts, D F Boyd, D N Middlemiss, C Routledg. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471095. |
in the dorsal hippocampus, whilst 5-ht1a receptor antagonism elicited by administration of way 100635 had no effect, both 5-ht1b and mixed 5-ht1b/1d receptor blockade significantly increased extracellular 5-ht levels. |
1999-10-25 |
2023-08-12 |
Not clear |
| C Roberts, D F Boyd, D N Middlemiss, C Routledg. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471095. |
these data demonstrate that to simultaneously increase extracellular 5-ht in both frontal cortex and dorsal hippocampus of the guinea-pig brain concurrent 5-hta1a, 5-ht1b and 5-ht1d receptor blockade is required. |
1999-10-25 |
2023-08-12 |
Not clear |
| C Roberts, D F Boyd, D N Middlemiss, C Routledg. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471095. |
whereas in the dorsal hippocampus, 5-ht1b receptor blockade is sufficient to elicit an increase in extracellular 5-ht levels. |
1999-10-25 |
2023-08-12 |
Not clear |
| A Raurich, G Mengod, F Artigas, R Corté. Displacement of the binding of 5-HT(1A) receptor ligands to pre- and postsynaptic receptors by (-)pindolol. A comparative study in rodent, primate and human brain. Synapse (New York, N.Y.). vol 34. issue 1. 1999-10-20. PMID:10459173. |
the affinity of (-)pindolol for presynaptic 5-ht(1a) receptors in the dorsal raphe nucleus was similar to that observed in postsynaptic locations, such as hippocampus (areas ca1, ca3 and dentate gyrus) or entorhinal cortex. |
1999-10-20 |
2023-08-12 |
human |
| G Juckel, A Mendlin, B L Jacob. Electrical stimulation of rat medial prefrontal cortex enhances forebrain serotonin output: implications for electroconvulsive therapy and transcranial magnetic stimulation in depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 3. 1999-10-19. PMID:10457536. |
in the present study, 5-ht efflux in the rat ventral hippocampus and amygdala was analyzed using in vivo microdialysis during low-current electrical stimulation of pfc and other cortical regions. |
1999-10-19 |
2023-08-12 |
rat |
| M N Subhash, K Y Vinod, B N Sriniva. Differential effect of lithium on 5-HT1 receptor-linked system in regions of rat brain. Neurochemistry international. vol 35. issue 4. 1999-10-18. PMID:10482354. |
we observed that chronic treatment of li2co3, significantly decreased the density of [3h]5-ht binding sites in cortex (62%), hippocampus (64%) and striatum (65%), compared to the control levels. |
1999-10-18 |
2023-08-12 |
rat |
| Y Zheng, P F Smith, C L Darlingto. Noradrenaline and serotonin levels in the guinea pig hippocampus following unilateral vestibular deafferentation. Brain research. vol 836. issue 1-2. 1999-10-15. PMID:10415419. |
noradrenaline and serotonin levels in the guinea pig hippocampus following unilateral vestibular deafferentation. |
1999-10-15 |
2023-08-12 |
Not clear |
| K G Harikumar, A Chattopadhya. Differential discrimination of G-protein coupling of serotonin(1A) receptors from bovine hippocampus by an agonist and an antagonist. FEBS letters. vol 457. issue 3. 1999-10-12. PMID:10471814. |
differential discrimination of g-protein coupling of serotonin(1a) receptors from bovine hippocampus by an agonist and an antagonist. |
1999-10-12 |
2023-08-12 |
cattle |
| K G Harikumar, A Chattopadhya. Differential discrimination of G-protein coupling of serotonin(1A) receptors from bovine hippocampus by an agonist and an antagonist. FEBS letters. vol 457. issue 3. 1999-10-12. PMID:10471814. |
we have studied the effect of guanosine-5'-o-(3-thiotriphosphate) (gtp-gamma-s), a non-hydrolyzable analogue of gtp, on agonist and antagonist binding to bovine hippocampal 5-hydroxytryptamine (5-ht)(1a) receptor in native membranes. |
1999-10-12 |
2023-08-12 |
cattle |
| K G Harikumar, A Chattopadhya. Differential discrimination of G-protein coupling of serotonin(1A) receptors from bovine hippocampus by an agonist and an antagonist. FEBS letters. vol 457. issue 3. 1999-10-12. PMID:10471814. |
this shows that the agonist and the antagonist differentially discriminate g-protein coupling of 5-ht(1a) receptors from bovine hippocampus. |
1999-10-12 |
2023-08-12 |
cattle |
| M Zhelyazkova-Savova, M G Giovannini, G Pepe. Systemic chlorophenylpiperazine increases acetylcholine release from rat hippocampus-implication of 5-HT2C receptors. Pharmacological research. vol 40. issue 2. 1999-10-08. PMID:10433876. |
the release of acetylcholine (ach) from the hippocampus of freely moving rats was studied after the systemic and local administration of the 5-ht agonist chlorophenylpiperazine (mcpp), utilising the in vivo microdialysis coupled to hplc. |
1999-10-08 |
2023-08-12 |
rat |
| F Blomstrand, N D Aberg, P S Eriksson, E Hansson, L Rönnbäc. Extent of intercellular calcium wave propagation is related to gap junction permeability and level of connexin-43 expression in astrocytes in primary cultures from four brain regions. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392848. |
incubation with 5-hydroxytryptamine decreased and incubation with glutamate increased the calcium wave propagation area in hippocampal (67% and 170% of the control, respectively) and in cortical astrocytes (82% and 163% of the control, respectively). |
1999-10-06 |
2023-08-12 |
rat |
| F Blomstrand, N D Aberg, P S Eriksson, E Hansson, L Rönnbäc. Extent of intercellular calcium wave propagation is related to gap junction permeability and level of connexin-43 expression in astrocytes in primary cultures from four brain regions. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392848. |
contrary to hippocampal and cortical astrocytes, the calcium wave propagation in brain stem astrocytes was increased by 5-hydroxytryptamine incubation (158% of control), while in hypothalamic astrocytes, no significant effects were seen. |
1999-10-06 |
2023-08-12 |
rat |
| O Berton, M Durand, S Aguerre, P Mormède, F Chaoulof. Behavioral, neuroendocrine and serotonergic consequences of single social defeat and repeated fluoxetine pretreatment in the Lewis rat strain. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392854. |
the density of hippocampal serotonin transporters, but not that of hippocampal serotonin-1a and cortical serotonin-2a receptors, was decreased by a single social defeat; in addition, neither tryptophan availability and serotonin synthesis/metabolism, nor serotonin-1a autoreceptor-mediated functions (inhibition of serotonin synthesis, hyperphagia) were affected. |
1999-10-06 |
2023-08-12 |
human |
| R Markstein, M Matsumoto, C Kohler, H Togashi, M Yoshioka, D Hoye. Pharmacological characterisation of 5-HT receptors positively coupled to adenylyl cyclase in the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 359. issue 6. 1999-10-04. PMID:10431755. |
pharmacological characterisation of 5-ht receptors positively coupled to adenylyl cyclase in the rat hippocampus. |
1999-10-04 |
2023-08-12 |
rat |