| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzon. Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 4. 2003-04-21. PMID:12237750. |
only acute, but not prolonged treatment with corticosterone decreased the level of 5-ht(1a) receptor mrna in the ca1 region and dentate gyrus of the hippocampus. |
2003-04-21 |
2023-08-12 |
rat |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzon. Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 4. 2003-04-21. PMID:12237750. |
5-ht turnover in the hippocampus was not influenced by chronic corticosterone. |
2003-04-21 |
2023-08-12 |
rat |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzon. Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 4. 2003-04-21. PMID:12237750. |
it is concluded that a chronically elevated level of corticosterone can induce functional desensitization of 5-ht(1a) receptors in the ca1 area of the hippocampus, although this effect is not always followed consequently by decreases in 5-ht(1a) receptor synthesis in this or other areas of the hippocampus. |
2003-04-21 |
2023-08-12 |
rat |
| Philip Heiser, Christiane Hausmann, Joachim Frey, Frank Geller, Ralf Becker, Wolfgang Wesemann, Jürgen Christian Krieg, Helmut Remschmidt, Helmut Vedde. Serotonergic effects of clozapine and its metabolites in hippocampal HT22 cells. Psychiatry research. vol 112. issue 3. 2003-04-17. PMID:12450631. |
in the hippocampal neuronal in vitro system of ht22 cells, we studied the effects of clozapine (cloz) and its metabolites clozapine-n-oxide (cloz-n-oxide) and norclozapine (norcloz) on 5-ht transporter affinity (k(m)) and uptake (v(max)), mao-b affinity (k(m)) and maximal velocity (v(max)), as well as on 5-ht(2) receptor affinity and density. |
2003-04-17 |
2023-08-12 |
Not clear |
| Chiara Ghersi, Andrea Bonfanti, Benedetta Manzari, Marco Feligioni, Maurizio Raiteri, Anna Pittalug. Pharmacological heterogeneity of release-regulating presynaptic AMPA/kainate receptors in the rat brain: study with receptor antagonists. Neurochemistry international. vol 42. issue 4. 2003-04-17. PMID:12470701. |
presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa)/kainate receptors mediating hippocampal [(3)h]noradrenaline or [(3)h]serotonin release, striatal [(3)h]dopamine release and cortical [(3)h]acetylcholine release were pharmacologically characterized using several ampa/kainate receptor antagonists. |
2003-04-17 |
2023-08-12 |
rat |
| Silvina L Diaz, Alma K Kemmling, Graciela N Baleri. Baclofen reestablishes striatal and cortical dopamine concentrations during naloxone-precipitated withdrawal. Neurochemistry international. vol 42. issue 4. 2003-04-17. PMID:12470702. |
ten minutes after these treatments, mice were killed by decapitation and the striatum, cortex and hippocampus were dissected to determine endogenous concentrations of dopamine (da), 5-hydroxytryptamine (5-ht) and their metabolites using hplc with electrochemical detection. |
2003-04-17 |
2023-08-12 |
mouse |
| M D S Lapiz, A Fulford, S Muchimapura, R Mason, T Parker, C A Marsde. Influence of postweaning social isolation in the rat on brain development, conditioned behavior, and neurotransmission. Neuroscience and behavioral physiology. vol 33. issue 1. 2003-04-14. PMID:12617300. |
isolation-reared rats have enhanced presynaptic dopamine (da) and 5-ht function in the nucleus accumbens (nac) associated with decreased presynaptic 5-ht function in the frontal cortex and hippocampus. |
2003-04-14 |
2023-08-12 |
human |
| Francesca Fernandez, Sophie Sarre, Jean-Marie Launay, Sylvie Aguerre, Véronique Guyonnet-Dupérat, Marie-Pierre Moisan, Guy Ebinger, Yvette Michotte, Pierre Mormède, Francis Chaoulof. Rat strain differences in peripheral and central serotonin transporter protein expression and function. The European journal of neuroscience. vol 17. issue 3. 2003-04-10. PMID:12581167. |
midbrain and hippocampal [3h]paroxetine binding at the 5-htt and hippocampal [3h]serotonin (5-ht) reuptake were increased in male and female f344 rats, compared to their lew counterparts, these strain differences being observed both in rats of commercial origin and in homebred rats. |
2003-04-10 |
2023-08-12 |
human |
| Francesca Fernandez, Sophie Sarre, Jean-Marie Launay, Sylvie Aguerre, Véronique Guyonnet-Dupérat, Marie-Pierre Moisan, Guy Ebinger, Yvette Michotte, Pierre Mormède, Francis Chaoulof. Rat strain differences in peripheral and central serotonin transporter protein expression and function. The European journal of neuroscience. vol 17. issue 3. 2003-04-10. PMID:12581167. |
saturation studies of midbrain and hippocampal [3h]paroxetine binding at the 5-htt, and hippocampal and blood platelet [3h]5-ht reuptake, also revealed significant strain differences in bmax and vmax values. |
2003-04-10 |
2023-08-12 |
human |
| Francesca Fernandez, Sophie Sarre, Jean-Marie Launay, Sylvie Aguerre, Véronique Guyonnet-Dupérat, Marie-Pierre Moisan, Guy Ebinger, Yvette Michotte, Pierre Mormède, Francis Chaoulof. Rat strain differences in peripheral and central serotonin transporter protein expression and function. The European journal of neuroscience. vol 17. issue 3. 2003-04-10. PMID:12581167. |
although f344 and lew rats differ in the activity of the hypothalamo-pituitary-adrenal (hpa) axis, manipulations of that axis revealed that the strain differences in hippocampal [3h]paroxetine binding at 5-htts and [3h]5-ht reuptake were not accounted for by corticosteroids. |
2003-04-10 |
2023-08-12 |
human |
| Francesca Fernandez, Sophie Sarre, Jean-Marie Launay, Sylvie Aguerre, Véronique Guyonnet-Dupérat, Marie-Pierre Moisan, Guy Ebinger, Yvette Michotte, Pierre Mormède, Francis Chaoulof. Rat strain differences in peripheral and central serotonin transporter protein expression and function. The European journal of neuroscience. vol 17. issue 3. 2003-04-10. PMID:12581167. |
hippocampal extracellular 5-ht levels were reduced in f344 rats, compared to lew rats, with the relative, but not the absolute, increase in extracellular 5-ht elicited by the local administration of citalopram being larger in f344 rats. |
2003-04-10 |
2023-08-12 |
human |
| S Body, S Kheramin, S Mobini, M-Y Ho, D N Velazquez-Martinez, C M Bradshaw, E Szabad. Antagonism by WAY-100635 of the effects of 8-OH-DPAT on performance on a free-operant timing schedule in intact and 5-HT-depleted rats. Behavioural pharmacology. vol 13. issue 8. 2003-04-09. PMID:12478210. |
5-ht levels in the neocortex, hippocampus, amygdala, nucleus accumbens and hypothalamus of the lesioned group were <20% of those in the sham-lesioned group; catecholamine levels were unaffected. |
2003-04-09 |
2023-08-12 |
rat |
| Daisuke Mochizuki, Tadami Hokonohara, Koh Kawasaki, Naomasa Mik. Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors. Journal of psychopharmacology (Oxford, England). vol 16. issue 3. 2003-04-07. PMID:12236634. |
treatment with milnacipran (30 mg/kg, p.o., twice daily) for 14 days did not change the inhibition of the ca1 field potential in rat hippocampal slices by 5-ht. |
2003-04-07 |
2023-08-12 |
rat |
| Lee A Dawson, Huy Q Nguyen, Ping L. Potentiation of amphetamine-induced changes in dopamine and 5-HT by a 5-HT(6) receptor antagonist. Brain research bulletin. vol 59. issue 6. 2003-04-04. PMID:12576149. |
although recent data has shown that 5-ht(6) receptor antagonists' can enhance basal cholinergic and glutamatergic neurotransmission in the cortex and hippocampus, the distribution of this receptor within terminal regions of the dopaminergic system suggests a possible role for this receptor in the modulation of dopamine (da). |
2003-04-04 |
2023-08-12 |
rat |
| Jingyuan Chen, Changpeng Shen, Emanuel Melle. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. European journal of pharmacology. vol 452. issue 2. 2003-04-02. PMID:12354565. |
in contrast to the effect in cells, the 5-ht(1a) receptor agonist 8-hydroxy-n,n-diproylaminotetralin (8-oh-dpat) dose- and time-dependently decreased basal levels of phosphorylated erk1/2 (phospho-erk1/2) in rat hippocampus (ed(50) approximately 0.1 mg/kg, maximum approximately 90%) without altering total erk1/2. |
2003-04-02 |
2023-08-12 |
rat |
| Jingyuan Chen, Changpeng Shen, Emanuel Melle. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. European journal of pharmacology. vol 452. issue 2. 2003-04-02. PMID:12354565. |
other 5-ht(1a) receptor agonists (buspirone, gepirone and ipsapirone) also reduced phospho-erk1/2 levels in hippocampus. |
2003-04-02 |
2023-08-12 |
rat |
| Patricia Laplante, Josie Diorio, Michael J Meane. Serotonin regulates hippocampal glucocorticoid receptor expression via a 5-HT7 receptor. Brain research. Developmental brain research. vol 139. issue 2. 2003-04-02. PMID:12480134. |
serotonin regulates hippocampal glucocorticoid receptor expression via a 5-ht7 receptor. |
2003-04-02 |
2023-08-12 |
Not clear |
| Patricia Laplante, Josie Diorio, Michael J Meane. Serotonin regulates hippocampal glucocorticoid receptor expression via a 5-HT7 receptor. Brain research. Developmental brain research. vol 139. issue 2. 2003-04-02. PMID:12480134. |
glucocorticoid receptor expression in primary hippocampal cell cultures was significantly increased with either 10 mm 8-bromo camp, 50 nm 5-carboxamidotryptamine (5-ct), a potent 5-ht7 receptor agonist, or 100 nm 5-ht. |
2003-04-02 |
2023-08-12 |
Not clear |
| Patricia Laplante, Josie Diorio, Michael J Meane. Serotonin regulates hippocampal glucocorticoid receptor expression via a 5-HT7 receptor. Brain research. Developmental brain research. vol 139. issue 2. 2003-04-02. PMID:12480134. |
these results suggest that the effects of 5-ht on hippocampal gr expression is mediated by a 5-ht7 receptor. |
2003-04-02 |
2023-08-12 |
Not clear |
| Gregers Wegener, Zhale Bandpey, Ida Louise Heiberg, Arne Mørk, Raben Rosenber. Increased extracellular serotonin level in rat hippocampus induced by chronic citalopram is augmented by subchronic lithium: neurochemical and behavioural studies in the rat. Psychopharmacology. vol 166. issue 2. 2003-04-02. PMID:12552361. |
increased extracellular serotonin level in rat hippocampus induced by chronic citalopram is augmented by subchronic lithium: neurochemical and behavioural studies in the rat. |
2003-04-02 |
2023-08-12 |
rat |