| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anelise Lazaris, Fabrice Bertrand, Christine Lazarus, Rodrigue Galani, Jeanne Stemmelin, Raphaël Poirier, Christian Kelche, Jean-Christophe Casse. Baseline and 8-OH-DPAT-induced release of acetylcholine in the hippocampus of aged rats with different levels of cognitive dysfunction. Brain research. vol 967. issue 1-2. 2003-06-05. PMID:12650979. |
subsequently, the efficiency of 5-ht(1a) receptor agonist 8-oh-dpat (0.5 mg/kg, s.c.) in triggering hippocampal acetylcholine release was evaluated by in vivo microdialysis and high performance liquid chromatography analysis. |
2003-06-05 |
2023-08-12 |
rat |
| Anelise Lazaris, Fabrice Bertrand, Christine Lazarus, Rodrigue Galani, Jeanne Stemmelin, Raphaël Poirier, Christian Kelche, Jean-Christophe Casse. Baseline and 8-OH-DPAT-induced release of acetylcholine in the hippocampus of aged rats with different levels of cognitive dysfunction. Brain research. vol 967. issue 1-2. 2003-06-05. PMID:12650979. |
the results suggest that (i) some aspects of cognitive alterations related to aging might be linked to the baseline release of acetylcholine in the hippocampus, and (ii) the cholinergic innervation of the hippocampus of aged rats responds almost normally to systemic activation of 5-ht(1a) receptors, and (iii) differential alterations of cholinergic/serotonergic interactions assessed by determination of the 8-oh-dpat-induced release of acetylcholine in the hippocampus could not be linked with clarity to the cognitive status of aged rats. |
2003-06-05 |
2023-08-12 |
rat |
| Victoria Luin. Sex differences in chronic stress effects on memory in rats. Stress (Amsterdam, Netherlands). vol 5. issue 3. 2003-06-03. PMID:12186683. |
stress decreased dopaminergic activity in the frontal cortex and amygdala of males but not females; whereas, in ca3 of the hippocampus, stress increased levels of 5-ht and norepinephrine in females, but not males, and increased gaba in males, but not females. |
2003-06-03 |
2023-08-12 |
human |
| A Busche, J Neddens, C Dinter, R R Dawirs, G Teuchert-Nood. Differential influence of rearing conditions and methamphetamine on serotonin fibre maturation in the dentate gyrus of gerbils (Meriones unguiculatus). Developmental neuroscience. vol 24. issue 6. 2003-05-30. PMID:12697989. |
the densities of immunostained 5-ht fibres were quantified in septal and temporal regions of the hippocampal dentate gyrus (dg) in young adult gerbils. |
2003-05-30 |
2023-08-12 |
Not clear |
| A Busche, J Neddens, C Dinter, R R Dawirs, G Teuchert-Nood. Differential influence of rearing conditions and methamphetamine on serotonin fibre maturation in the dentate gyrus of gerbils (Meriones unguiculatus). Developmental neuroscience. vol 24. issue 6. 2003-05-30. PMID:12697989. |
according to our previous studies on hippocampal neurogenesis, adaptations of 5-ht fibre densities partly proved to be positively correlated to cell proliferation rates for each of the specific conditions. |
2003-05-30 |
2023-08-12 |
Not clear |
| Johannes A Van Hooft, Wytse J Wadma. Ca2+ ions block and permeate serotonin 5-HT3 receptor channels in rat hippocampal interneurons. Journal of neurophysiology. vol 89. issue 4. 2003-05-29. PMID:12611954. |
ca2+ ions block and permeate serotonin 5-ht3 receptor channels in rat hippocampal interneurons. |
2003-05-29 |
2023-08-12 |
rat |
| M Chennaoui, C Drogou, D Gomez-Merino, C Y Guezenne. The effects of long-term adrenalectomy on 5-HT1B receptors mRNA expression in cerebellum, striatum, frontal cortex and hippocampus of rats. Neuroscience letters. vol 340. issue 2. 2003-05-29. PMID:12668254. |
we evaluated the effects of adrenalectomy (adx) on 5-ht(1b) receptors mrna expression in cerebellum, frontal cortex, striatum and hippocampus in rats, using the rnase protection assay technique. |
2003-05-29 |
2023-08-12 |
rat |
| M Chennaoui, C Drogou, D Gomez-Merino, C Y Guezenne. The effects of long-term adrenalectomy on 5-HT1B receptors mRNA expression in cerebellum, striatum, frontal cortex and hippocampus of rats. Neuroscience letters. vol 340. issue 2. 2003-05-29. PMID:12668254. |
the expression of 5-ht(1b) receptors mrna was unchanged in the hippocampus and in the striatum. |
2003-05-29 |
2023-08-12 |
rat |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. |
2003-05-21 |
2023-08-12 |
rat |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
microdialysis for measurement of serotonin in the paraventricular nucleus of the hypothalamus (pvn) and the dorsal hippocampus was performed under both basal and stimulated conditions, known to elicit differential behavioral and neuroendocrine responses in rats with inborn high (hab) or low (lab) anxiety-related behavior. |
2003-05-21 |
2023-08-12 |
rat |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
we studied the release of hypothalamic and hippocampal serotonin in response to elevated platform exposure and forced swim stress, a mild emotional and a combined emotional and physical stressor, respectively. |
2003-05-21 |
2023-08-12 |
rat |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
under basal conditions, no differences in serotonin release in either the pvn or dorsal hippocampus were observed between hab and lab rats. |
2003-05-21 |
2023-08-12 |
rat |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
in the dorsal hippocampus, only labs, but not habs, responded to the elevated platform exposure by enhancing the release of serotonin (p = 0.01). |
2003-05-21 |
2023-08-12 |
rat |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
also, forced swim stress increased hippocampal serotonin only in lab (p = 0.002), but not hab, rats probably indicating an involvement of hippocampal serotonin in locomotion and active stress coping. |
2003-05-21 |
2023-08-12 |
rat |
| H Takeda, M Tsuji, Y Fujisawa, T Yamada, K Tsuji, T Egashira, T Matsumiy. Intracerebroventricular administration of endothelin-1 impairs the habituation of rats to a novel environment in conjunction with brain serotonergic activation. Neuroscience. vol 117. issue 2. 2003-05-21. PMID:12614685. |
administration of endothelin-1 (1 pmol) significantly increased the serotonin (5-hydroxytryptamine) turnover in some brain regions, i.e., the cerebral cortex, hippocampus and midbrain, and the inhibition of brain 5-hydroxytryptamine synthesis by treatment with p-chlorophenylalanine (200 mg/kg/day, s.c.) for 2 days suppressed the behavioral effects of endothelin-1 (1 pmol, i.c.v.). |
2003-05-21 |
2023-08-12 |
rat |
| Evan L Riddle, Kristi S Rau, Matthew K Topham, Glen R Hanson, Annette E Fleckenstei. Ceramide-induced alterations in dopamine transporter function. European journal of pharmacology. vol 458. issue 1-2. 2003-05-16. PMID:12498904. |
rather, the increase appeared to result from an increase in 5-ht transport through the dopamine transporter, an assertion evidenced by findings that this increase: (1) does not occur in hippocampal synaptosomes (i.e., a preparation largely devoid of dopamine transporters), (2) occurs in striatal synaptosomes prepared from para-chloroamphetamine-treated rats (i.e., a preparation lacking 5-ht transporters), (3) is attenuated by pretreatment with methylphenidate (i.e., a relatively selective dopamine reuptake inhibitor) and (4) is inhibited by exposure to exogenous dopamine (i.e., which presumably competes for uptake with 5-ht). |
2003-05-16 |
2023-08-12 |
rat |
| Arata Watanabe, Yoshihiro Tohyama, Khanh Q Nguyen, Shu Hasegawa, Guy Debonnel, Mirko Diksi. Regional brain serotonin synthesis is increased in the olfactory bulbectomy rat model of depression: an autoradiographic study. Journal of neurochemistry. vol 85. issue 2. 2003-05-14. PMID:12675923. |
there were also increases in 5-hydroxytryptamine (5-ht) synthesis in some limbic areas: the cingulate (32%), the medial forebrain bundle (58%), the hippocampus (13-25%) and the thalamus (22-40%). |
2003-05-14 |
2023-08-12 |
human |
| Tangi R Summers, John M Matter, Jennifer M McKay, Patrick J Ronan, Earl T Larson, Kenneth J Renner, Cliff H Summer. Rapid glucocorticoid stimulation and GABAergic inhibition of hippocampal serotonergic response: in vivo dialysis in the lizard anolis carolinensis. Hormones and behavior. vol 43. issue 1. 2003-05-09. PMID:12614656. |
to test the neuromodulatory effect of stress hormone secretion, serotonin overflow was measured from the hippocampus of the lizard anolis carolinensis. |
2003-05-09 |
2023-08-12 |
Not clear |
| Jason J Radley, Barry L Jacob. Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism. Brain research. vol 966. issue 1. 2003-05-08. PMID:12646302. |
in the present study, it was found that blockade of the 5-ht(1a) receptor before and after pilocarpine treatment prevented seizure-induced hippocampal cell proliferation and survival, and, its prevention by chronic treatment with a 5-ht(1a) receptor antagonist (way-100,635) did not prevent the development of mfs or spontaneously recurring seizures. |
2003-05-08 |
2023-08-12 |
rat |
| K Iwamoto, T Kat. Effects of cocaine and reserpine administration on RNA editing of rat 5-HT2C receptor estimated by primer extension combined with denaturing high-performance liquid chromatography. The pharmacogenomics journal. vol 2. issue 5. 2003-05-06. PMID:12439740. |
by using this, rna editing efficiencies of 5-ht(2c)r in the midbrain and hippocampus as well as the cerebral cortex were examined, and no alterations were found among these regions. |
2003-05-06 |
2023-08-12 |
rat |