| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Yoshitake, Ilkka Reenilä, Sven Ove Ogren, Tomas Hökfelt, Jan Keh. Galanin attenuates basal and antidepressant drug-induced increase of extracellular serotonin and noradrenaline levels in the rat hippocampus. Neuroscience letters. vol 339. issue 3. 2003-05-05. PMID:12633897. |
galanin attenuates basal and antidepressant drug-induced increase of extracellular serotonin and noradrenaline levels in the rat hippocampus. |
2003-05-05 |
2023-08-12 |
rat |
| Takashi Yoshitake, Ilkka Reenilä, Sven Ove Ogren, Tomas Hökfelt, Jan Keh. Galanin attenuates basal and antidepressant drug-induced increase of extracellular serotonin and noradrenaline levels in the rat hippocampus. Neuroscience letters. vol 339. issue 3. 2003-05-05. PMID:12633897. |
in the present study, the effects of galanin on extracellular 5-ht and na levels in the rat hippocampus were measured by in vivo microdialysis under basal conditions and following systemic administration of antidepressant drugs. |
2003-05-05 |
2023-08-12 |
rat |
| S A Tucci, R F Genn, S E Fil. Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors. Neuropharmacology. vol 44. issue 3. 2003-05-02. PMID:12604094. |
methyllycaconitine (mla) blocks the nicotine evoked anxiogenic effect and 5-ht release in the dorsal hippocampus: possible role of alpha7 receptors. |
2003-05-02 |
2023-08-12 |
Not clear |
| S A Tucci, R F Genn, S E Fil. Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors. Neuropharmacology. vol 44. issue 3. 2003-05-02. PMID:12604094. |
the dorsal hippocampus is one of the brain areas that mediate the anxiogenic effect of nicotine through enhanced 5-ht release, but the nachr subtype(s) that mediate these effects are not known. |
2003-05-02 |
2023-08-12 |
Not clear |
| S A Tucci, R F Genn, S E Fil. Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors. Neuropharmacology. vol 44. issue 3. 2003-05-02. PMID:12604094. |
exposure of hippocampal slices to mla (0.25, 05, 1 and 10 micro m) significantly reduced the increase in [(3)h]5-ht release evoked by nicotine (100 micro m). |
2003-05-02 |
2023-08-12 |
Not clear |
| S A Tucci, R F Genn, S E Fil. Methyllycaconitine (MLA) blocks the nicotine evoked anxiogenic effect and 5-HT release in the dorsal hippocampus: possible role of alpha7 receptors. Neuropharmacology. vol 44. issue 3. 2003-05-02. PMID:12604094. |
however, what is most important is that, in the dorsal hippocampus, nicotine's anxiogenic effect and induced release of [(3)h]5-ht are mediated by non alpha4beta2 nachrs, which contrasts with the previously reported anxiolytic effect of a low dose of nicotine which is mediated by alpha4beta2 nachrs within the dorsal raphé nucleus. |
2003-05-02 |
2023-08-12 |
Not clear |
| Sterling N Sudweeks, Johannes A van Hooft, Jerrel L Yake. Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization. The Journal of physiology. vol 544. issue 3. 2003-05-01. PMID:12411518. |
serotonin 5-ht(3) receptors in rat ca1 hippocampal interneurons: functional and molecular characterization. |
2003-05-01 |
2023-08-12 |
rat |
| Sterling N Sudweeks, Johannes A van Hooft, Jerrel L Yake. Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization. The Journal of physiology. vol 544. issue 3. 2003-05-01. PMID:12411518. |
in half of the interneurons examined, mtsea significantly enhanced the amplitude of the 5-ht(3)r-mediated responses, which is consistent with the notion that the alpha4-nachr subunit co-assembles with the 5-ht(3a) subunit to form a native heteromeric 5-ht(3)r channel in rat ca1 hippocampal interneurons in vivo. |
2003-05-01 |
2023-08-12 |
rat |
| A Bhattacharya, A V Muruganandam, Vikas Kumar, S K Bhattachary. Effect of poly herbal formulation, EuMil, on neurochemical perturbations induced by chronic stress. Indian journal of experimental biology. vol 40. issue 10. 2003-05-01. PMID:12693697. |
chronic electroshock stress (14 days) significantly decreased the nor-adrenaline (na) and dopamine (da) levels in frontal cortex, pons-medulla, hypothalamus, hippocampus and striatal, hypothalamal region, respectively, and increased the 5-hydroxytryptamine (5ht) level in frontal cortex, pons medulla, hypothalamus and hippocampus. |
2003-05-01 |
2023-08-12 |
rat |
| M Elena Castro, Alvaro Diaz, Elena del Olmo, Angel Pazo. Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT1A receptors in rat brain. Neuropharmacology. vol 44. issue 1. 2003-04-30. PMID:12559126. |
moreover, a relevant finding is the region-specific hypersensitivity of postsynaptic 5-ht(1a) receptors, in the hippocampus but not in entorhinal cortex, following chronic fluoxetine. |
2003-04-30 |
2023-08-12 |
rat |
| Nahid Majlessi, Mehri Kadkhodaee, Mohsen Parviz, Nasser Naghd. Serotonin depletion in rat hippocampus attenuates L-NAME-induced spatial learning deficits. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560130. |
serotonin depletion in rat hippocampus attenuates l-name-induced spatial learning deficits. |
2003-04-28 |
2023-08-12 |
rat |
| Nahid Majlessi, Mehri Kadkhodaee, Mohsen Parviz, Nasser Naghd. Serotonin depletion in rat hippocampus attenuates L-NAME-induced spatial learning deficits. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560130. |
recent studies also suggest a regulatory effect of endogenous no on hippocampal serotonin (5-ht) release and have shown that no-synthase (nos) inhibitors increased extracellular levels of serotonin (5-ht) in the rat hippocampus. |
2003-04-28 |
2023-08-12 |
rat |
| Nahid Majlessi, Mehri Kadkhodaee, Mohsen Parviz, Nasser Naghd. Serotonin depletion in rat hippocampus attenuates L-NAME-induced spatial learning deficits. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560130. |
to clarify possible interactions between no and 5-ht in the hippocampus on learning processes, the effect of selective hippocampal 5-ht depletion on nos inhibition-induced spatial learning deficits was investigated. |
2003-04-28 |
2023-08-12 |
rat |
| Nahid Majlessi, Mehri Kadkhodaee, Mohsen Parviz, Nasser Naghd. Serotonin depletion in rat hippocampus attenuates L-NAME-induced spatial learning deficits. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560130. |
rats received bilateral injections of 5,7-dihydroxytryptamine (5,7-dht), a 5-ht neurotoxin, or its vehicle in the ca1 region of hippocampus following pretreatment with desipramine. |
2003-04-28 |
2023-08-12 |
rat |
| Nahid Majlessi, Mehri Kadkhodaee, Mohsen Parviz, Nasser Naghd. Serotonin depletion in rat hippocampus attenuates L-NAME-induced spatial learning deficits. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560130. |
the observed effect suggests an interaction between no and 5-ht in the hippocampus on spatial memory formation; however, the mechanism of interaction is still unclear and requires further investigation. |
2003-04-28 |
2023-08-12 |
rat |
| A Schmitt, R Mössner, A Gossmann, I G Fischer, V Gorboulev, D L Murphy, H Koepsell, K P Lesc. Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice. Journal of neuroscience research. vol 71. issue 5. 2003-04-24. PMID:12584728. |
up-regulation of oct3 expression and enhanced low-affinity 5ht uptake may limit the adverse effects of elevated extracellular 5ht and may play a critical role in maintaining 5ht-dependent functions of the hippocampus in the absence of 5htt. |
2003-04-24 |
2023-08-12 |
mouse |
| Jon E Sprague, Matthew L Banks, Valerie J Cook, Edward M Mill. Hypothalamic-pituitary-thyroid axis and sympathetic nervous system involvement in hyperthermia induced by 3,4-methylenedioxymethamphetamine (Ecstasy). The Journal of pharmacology and experimental therapeutics. vol 305. issue 1. 2003-04-22. PMID:12649364. |
the hypo and tx animals were also resistant to the serotonergic neurotoxic effects of mdma assessed by serotonin measurements 4 to 7 days later in the striatum and hippocampus. |
2003-04-22 |
2023-08-12 |
rat |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzon. Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 4. 2003-04-21. PMID:12237750. |
hippocampal 5-ht(1a) receptors have been shown to be suppressed by glucocorticoids in a variety of animal studies, however the molecular mechanism and the functional meaning of this effect are still not well understood. |
2003-04-21 |
2023-08-12 |
rat |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzon. Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 4. 2003-04-21. PMID:12237750. |
the present study was designed to investigate the impact of repeated administration of corticosterone (10 mg/kg s.c. twice daily for 7 days) on the functional consequences of 5-ht(1a) receptor stimulation measured electrophysiologically in hippocampal slices. |
2003-04-21 |
2023-08-12 |
rat |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Krzysztof Tokarski, Maria Bijak, Krzysztof Wedzon. Prolonged corticosterone treatment alters the responsiveness of 5-HT1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 4. 2003-04-21. PMID:12237750. |
additionally, the effects of corticosterone on 5-ht(1a) receptor binding and on receptor mrna levels in the hippocampus were studied. |
2003-04-21 |
2023-08-12 |
rat |