| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E van Riel, O C Meijer, P J Steenbergen, M Joël. Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895506. |
in hippocampal tissue from thus stressed rats mrna expression of the 5-ht(1a) receptor and mineralo- as well as glucocorticoid receptors were examined with in situ hybridization. |
2003-12-04 |
2023-08-12 |
rat |
| E van Riel, O C Meijer, P J Steenbergen, M Joël. Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895506. |
the 5-ht(1a) receptor mrna expression was not changed after chronic stress exposure, in any of the hippocampal areas. |
2003-12-04 |
2023-08-12 |
rat |
| Brian H Harvey, Carla Naciti, Linda Brand, Dan J Stei. Endocrine, cognitive and hippocampal/cortical 5HT 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914970. |
due to the putative role of serotonin in anxiety and stress, and in the treatment of ptsd, hippocampal 5ht(1a) and prefrontal cortex 5ht(2a) radioligand binding studies were performed. |
2003-11-28 |
2023-08-12 |
rat |
| Brian H Harvey, Carla Naciti, Linda Brand, Dan J Stei. Endocrine, cognitive and hippocampal/cortical 5HT 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914970. |
cognitive and endocrine changes at day 7 post stress were associated with a significant increase in receptor density (b(max)) and a significant decrease in receptor affinity (k(d)) for hippocampal 5ht(1a) receptors. |
2003-11-28 |
2023-08-12 |
rat |
| Yossef Itzhak, Syed F Ali, Karen L Anderso. Fenfluramine-induced serotonergic neurotoxicity in mice: lack of neuroprotection by inhibition/ablation of nNOS. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969273. |
selective depletion of 5-ht and 5-ht transporter binding sites in the striatum, frontal cortex and hippocampus in all three mouse strains was observed, with no evidence of dopaminergic neurotoxicity. |
2003-11-12 |
2023-08-12 |
mouse |
| Mayuko Kino, Takako Yamato, Masahiro Aomin. Simultaneous measurement of nitric oxide, blood glucose, and monoamines in the hippocampus of diabetic rat: an in vivo microdialysis study. Neurochemistry international. vol 44. issue 2. 2003-11-12. PMID:12971908. |
the results in the present study showed that: (1) the plasma levels of nox in both diabetic rats were low compared to those in control rats, (2) the hippocampal nox levels in both diabetic rats were almost the same as those in control rats, while the levels of 5-ht and da were low in the diabetics, and (3) a sudden decrease in the plasma glucose level due to insulin administration reduced the nox level as well as enhanced the 5-ht level in the diabetic hippocampus, a finding consistent with the results of 7 days administration of insulin. |
2003-11-12 |
2023-08-12 |
rat |
| Latifa Rbah, Vincent Leviel, Luc Zimme. Displacement of the PET ligand 18F-MPPF by the electrically evoked serotonin release in the rat hippocampus. Synapse (New York, N.Y.). vol 49. issue 4. 2003-11-10. PMID:12827643. |
displacement of the pet ligand 18f-mppf by the electrically evoked serotonin release in the rat hippocampus. |
2003-11-10 |
2023-08-12 |
rat |
| Latifa Rbah, Vincent Leviel, Luc Zimme. Displacement of the PET ligand 18F-MPPF by the electrically evoked serotonin release in the rat hippocampus. Synapse (New York, N.Y.). vol 49. issue 4. 2003-11-10. PMID:12827643. |
the effects of the electrically evoked serotonin release were evaluated on the binding of (18)f-mppf in the hippocampus of anesthetized rats. |
2003-11-10 |
2023-08-12 |
rat |
| C K J Lieben, A Blokland, B Westerink, N E P Deut. Acute tryptophan and serotonin depletion using an optimized tryptophan-free protein-carbohydrate mixture in the adult rat. Neurochemistry international. vol 44. issue 1. 2003-11-05. PMID:12963083. |
furthermore, the concentrations of amino acid, serotonin (5-ht), dopamine (da) and their metabolite (5-hydroxyindolacetic acid (5-hiaa) and 3,4-dihydroxyphenylacetic acid (dopac), respectively) were measured within the striatum, hippocampus and cortex. |
2003-11-05 |
2023-08-12 |
rat |
| Luc Zimmer, Latifa Rbah, Fabrice Giacomelli, Didier Le Bars, Bernard Renau. A reduced extracellular serotonin level increases the 5-HT1A PET ligand 18F-MPPF binding in the rat hippocampus. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 44. issue 9. 2003-10-31. PMID:12960198. |
a reduced extracellular serotonin level increases the 5-ht1a pet ligand 18f-mppf binding in the rat hippocampus. |
2003-10-31 |
2023-08-12 |
rat |
| Jon E Sprague, Amanda S Preston, Michael Leifheit, Brian Woodsid. Hippocampal serotonergic damage induced by MDMA (ecstasy): effects on spatial learning. Physiology & behavior. vol 79. issue 2. 2003-10-29. PMID:12834800. |
mdma treatment resulted in significant reduction (34%) in hippocampal serotonin (5-ht) levels 14 days after initial treatment. |
2003-10-29 |
2023-08-12 |
rat |
| Eliyahu Dremencov, Eitan Gur, Bernard Lerer, Michael E Newma. Effects of chronic antidepressants and electroconvulsive shock on serotonergic neurotransmission in the rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 5. 2003-10-23. PMID:12921903. |
there are two main lines of evidence for this: firstly, many of its functions correspond to those altered in depression, and secondly, many hippocampal functions are regulated by the serotonergic (5-ht) system, which is a common target of antidepressant treatments. |
2003-10-23 |
2023-08-12 |
rat |
| R C B Silva, A P M Cruz, V Avanzi, J Landeira-Fernandez, M L Brandã. Distinct contributions of median raphe nucleus to contextual fear conditioning and fear-potentiated startle. Neural plasticity. vol 9. issue 4. 2003-10-23. PMID:12959153. |
ascending 5-ht projections from the median raphe nucleus (mrn), probably to the hippocampus, are implicated in the acquisition of contextual fear (background stimuli), as assessed by freezing behavior. |
2003-10-23 |
2023-08-12 |
rat |
| Eric Vermetten, Meena Vythilingam, Steven M Southwick, Dennis S Charney, J Douglas Bremne. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biological psychiatry. vol 54. issue 7. 2003-10-23. PMID:14512209. |
recent preclinical evidence has shown that selective serotonin reuptake inhibitors promote neurogenesis and reverse the effects of stress on hippocampal atrophy. |
2003-10-23 |
2023-08-12 |
Not clear |
| G Csaba, Barbara Knippel, Cs Karabélyos, Agnes Inczefi-Gonda, Monika Hantos, Kornélia Teke. Impact of single neonatal serotonin treatment (hormonal imprinting) on the brain serotonin content and sexual behavior of adult rats. Life sciences. vol 73. issue 21. 2003-10-21. PMID:13679238. |
in other regions of the male brain (prefrontal cortex, hypothalamus, hippocampus) there was a statistically non-significant tendency for a decrease in serotonin level. |
2003-10-21 |
2023-08-12 |
rat |
| Andrew Harkin, Eamonn Shanahan, John P Kelly, Thomas J Conno. Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine. The European journal of neuroscience. vol 18. issue 4. 2003-10-14. PMID:12925028. |
mda pretreatment resulted in 5-ht nerve terminal degeneration, indicated by reduced 5-ht and 5-hiaa concentrations in the frontal cortex, amygdala and hippocampus, and reduced [3h]paroxetine binding in the frontal cortex. |
2003-10-14 |
2023-08-12 |
rat |
| Andrew Harkin, Eamonn Shanahan, John P Kelly, Thomas J Conno. Methylenendioxyamphetamine produces serotonin nerve terminal loss and diminished behavioural and neurochemical responses to the antidepressant fluoxetine. The European journal of neuroscience. vol 18. issue 4. 2003-10-14. PMID:12925028. |
in vehicle-treated rats, fluoxetine (5 and 20 mg/kg) decreased 5-ht metabolism (5-hiaa : 5-ht ratio) in the frontal cortex, amygdala and hippocampus. |
2003-10-14 |
2023-08-12 |
rat |
| Massimiliano Bianchi, Christian Heidbreder, Francesco Cresp. Cytoskeletal changes in the hippocampus following restraint stress: role of serotonin and microtubules. Synapse (New York, N.Y.). vol 49. issue 3. 2003-10-07. PMID:12774303. |
cytoskeletal changes in the hippocampus following restraint stress: role of serotonin and microtubules. |
2003-10-07 |
2023-08-12 |
rat |
| Massimiliano Bianchi, Christian Heidbreder, Francesco Cresp. Cytoskeletal changes in the hippocampus following restraint stress: role of serotonin and microtubules. Synapse (New York, N.Y.). vol 49. issue 3. 2003-10-07. PMID:12774303. |
stressful conditions have also been shown to affect neuronal plasticity and 5-ht neurotransmission in the hippocampus. |
2003-10-07 |
2023-08-12 |
rat |
| Massimiliano Bianchi, Christian Heidbreder, Francesco Cresp. Cytoskeletal changes in the hippocampus following restraint stress: role of serotonin and microtubules. Synapse (New York, N.Y.). vol 49. issue 3. 2003-10-07. PMID:12774303. |
in addition, ex vivo hippocampal 5-ht levels were monitored by differential pulse voltammetry to analyse the influence of both stress conditions upon 5-ht levels. |
2003-10-07 |
2023-08-12 |
rat |