| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M F Piacentini, R Clinckers, R Meeusen, S Sarre, G Ebinger, Y Michott. Effects of venlafaxine on extracellular 5-HT, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954452. |
effects of venlafaxine on extracellular 5-ht, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo. |
2003-09-30 |
2023-08-12 |
rat |
| M F Piacentini, R Clinckers, R Meeusen, S Sarre, G Ebinger, Y Michott. Effects of venlafaxine on extracellular 5-HT, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954452. |
the purpose of the present study was to study the effect of an acute dose of the serotonin (5-ht) - noradrenaline (na) reuptake inhibitor venlafaxine on extracellular concentrations of 5-ht, na and dopamine (da) in the hippocampus and on the peripheral hormone concentrations in freely moving rats. |
2003-09-30 |
2023-08-12 |
rat |
| M F Piacentini, R Clinckers, R Meeusen, S Sarre, G Ebinger, Y Michott. Effects of venlafaxine on extracellular 5-HT, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954452. |
extracellular hippocampal na and 5-ht as determined with in vivo microdialysis increased significantly after drug injection. |
2003-09-30 |
2023-08-12 |
rat |
| M F Piacentini, R Clinckers, R Meeusen, S Sarre, G Ebinger, Y Michott. Effects of venlafaxine on extracellular 5-HT, dopamine and noradrenaline in the hippocampus and on peripheral hormone concentrations in the rat in vivo. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954452. |
at the selected dose venlafaxine is able to increase the release of 5-ht but also of na in rat hippocampus. |
2003-09-30 |
2023-08-12 |
rat |
| J Micallef, S Tardieu, S Gentile, E Fakra, E Jouve, R Sambuc, O Bli. [Effects of a subanaesthetic dose of ketamine on emotional and behavioral state in healthy subjects]. Neurophysiologie clinique = Clinical neurophysiology. vol 33. issue 3. 2003-09-23. PMID:12909392. |
the recent findings of ketamine's pharmacology and imaging studies allow to draw several hypothesis related to neurotransmitter systems (glutamate, dopamine, serotonin interactions) and cerebral areas (particularly prefrontal cortex, anterior cingulate cortex, hippocampus) underlying some of these ketamine-induced effects. |
2003-09-23 |
2023-08-12 |
human |
| Takashi Yoshitake, Kaoru Fujino, Jan Kehr, Junichi Ishida, Hitoshi Nohta, Masatoshi Yamaguch. Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine. Analytical biochemistry. vol 312. issue 2. 2003-09-16. PMID:12531196. |
the basal levels of ne, 5ht, and 5hiaa in the dialysates from the hippocampus were 4.2+/-0.5, 4.9+/-0.6, and 934.1 +/- 63.4 fmol/20 microl, and those from the prefrontal cortex were 6.0+/-1.2,5.51.3, and 669.1 +/- 96.0 fmol/20 microl (mean +/- se, n=25), respectively. |
2003-09-16 |
2023-08-12 |
rat |
| Lydia Schiller, Monika Jähkel, Marion Kretzschmar, Peter Brust, Jochen Oehle. Autoradiographic analyses of 5-HT1A and 5-HT2A receptors after social isolation in mice. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867255. |
intermediate isolation reduced 5-ht(1a) receptors especially in the lateral frontal, parietal and entorhinal cortex (-63%), in the lateral ca1-3 and dentate gyrus region of the hippocampus (-68%), in the basolateral, basomedial, central and medial amygdaloid nuclei (between -38 and -66%), and in the hypothalamus (-28%). |
2003-09-16 |
2023-08-12 |
mouse |
| Lydia Schiller, Monika Jähkel, Marion Kretzschmar, Peter Brust, Jochen Oehle. Autoradiographic analyses of 5-HT1A and 5-HT2A receptors after social isolation in mice. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867255. |
5-ht(2a) receptors were strongly reduced in the frontal cortex (between -47 and -74%), in the hippocampus (between -47 and -95%), in the striatum (between -66 and -76%), and in the accumbens nucleus (between -59 and -73%) in comparison to group housed control mice. |
2003-09-16 |
2023-08-12 |
mouse |
| Lydia Schiller, Monika Jähkel, Marion Kretzschmar, Peter Brust, Jochen Oehle. Autoradiographic analyses of 5-HT1A and 5-HT2A receptors after social isolation in mice. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867255. |
after 12 weeks of isolation in the hippocampus continuously decreased 5-ht(1a) receptor densities were demonstrated (between -24 and -61%). |
2003-09-16 |
2023-08-12 |
mouse |
| Lydia Schiller, Monika Jähkel, Marion Kretzschmar, Peter Brust, Jochen Oehle. Autoradiographic analyses of 5-HT1A and 5-HT2A receptors after social isolation in mice. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867255. |
isolated animals showed diminished 5-ht(1a) receptor densities in the cortex (-14%) and hippocampus (-15%), but increased 5-ht(1a) receptor densities in the amygdala (+33%) after 12 weeks. |
2003-09-16 |
2023-08-12 |
mouse |
| Iain S McGregor, Kelly J Clemens, Geoffrey Van der Plasse, Kong M Li, Glenn E Hunt, Feng Chen, Andrew J Lawrenc. Increased anxiety 3 months after brief exposure to MDMA ("Ecstasy") in rats: association with altered 5-HT transporter and receptor density. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 8. 2003-09-12. PMID:12700695. |
rats given the high-, but not the low-, dose mdma treatment regimen exhibited significant loss of 5-hydroxytryptamine (5-ht) and 5-hiaa in the amygdala, hippocampus, striatum, and cortex. |
2003-09-12 |
2023-08-12 |
rat |
| Iain S McGregor, Kelly J Clemens, Geoffrey Van der Plasse, Kong M Li, Glenn E Hunt, Feng Chen, Andrew J Lawrenc. Increased anxiety 3 months after brief exposure to MDMA ("Ecstasy") in rats: association with altered 5-HT transporter and receptor density. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 8. 2003-09-12. PMID:12700695. |
low-dose mdma decreased 5ht(1b) receptor density in the hippocampus, globus pallidus, and medial thalamus. |
2003-09-12 |
2023-08-12 |
rat |
| P Dahlqvist, A Rönnbäck, A Risedal, R Nergårdh, I-M Johansson, J R Seckl, B B Johansson, T Olsso. Effects of postischemic environment on transcription factor and serotonin receptor expression after permanent focal cortical ischemia in rats. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809685. |
5-hydroxytryptamine receptor 1a (5-ht(1a)) mrna expression and binding, as well as 5-ht(2a) receptor mrna expression were decreased in the hippocampus (ca4 region) of the running wheel rats. |
2003-09-12 |
2023-08-12 |
rat |
| Sâmia Regiane Lourenço Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. Activation of post-synaptic 5-HT(1A) receptors in the dorsal hippocampus prevents learned helplessness development. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834912. |
activation of post-synaptic 5-ht(1a) receptors in the dorsal hippocampus prevents learned helplessness development. |
2003-09-08 |
2023-08-12 |
rat |
| Sâmia Regiane Lourenço Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. Activation of post-synaptic 5-HT(1A) receptors in the dorsal hippocampus prevents learned helplessness development. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834912. |
activation of post-synaptic 5-ht(1a) receptors in the dorsal hippocampus is proposed to mediate stress adaptation. |
2003-09-08 |
2023-08-12 |
rat |
| Sâmia Regiane Lourenço Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. Activation of post-synaptic 5-HT(1A) receptors in the dorsal hippocampus prevents learned helplessness development. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834912. |
to test the hypothesis that increasing serotonin levels in the dorsal hippocampus would attenuate the development of learned helplessness, rats received inescapable foot-shock (pre-test session) and were tested in a shuttle box 24-h later. |
2003-09-08 |
2023-08-12 |
rat |
| Sâmia Regiane Lourenço Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. Activation of post-synaptic 5-HT(1A) receptors in the dorsal hippocampus prevents learned helplessness development. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834912. |
these data suggest that facilitation of serotonergic neurotransmission in the dorsal hippocampus mediates adaptation to severe inescapable stress, probably through the activation of post-synaptic 5-ht(1a) receptors. |
2003-09-08 |
2023-08-12 |
rat |
| A González-Quevedo, F Obregón, M Urbina, T Roussó, L Lim. Effects of taurine deficiency and chronic methanol administration on rat retina, optic nerve and brain amino acids and monoamines. Nutritional neuroscience. vol 6. issue 4. 2003-09-03. PMID:12887142. |
the association of beta-ala with mtx-meoh produced an increase of threonine, and a decrease of 5-hydroxytryptamine (5-ht) in the retina without modifying 5-hydroxyindoleacetic acid, whereas in the hippocampus an elevation of asparagine was observed. |
2003-09-03 |
2023-08-12 |
rat |
| D Papagiannopoulou, I Pirmettis, Ch Tsoukalas, L Nikoladou, G Drossopoulou, C Dalla, M Pelecanou, Z Papadopoulou-Daifotis, M Papadopoulos, E Chiotelli. Oxotechnetium 99mTcO[SN(R)S][S] complexes as potential 5-HT1A receptor imaging agents. Nuclear medicine and biology. vol 29. issue 8. 2003-09-02. PMID:12453592. |
as demonstrated by appropriate competition binding tests in rat hippocampal preparations, all oxorhenium analogues showed affinity for the 5-ht(1a) receptor binding sites with ic(50) values at the nanomolar range (ic(50)= 5.8-103 nm). |
2003-09-02 |
2023-08-12 |
rat |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Anna Gadek-Michalska, Krzysztof Wedzon. 8-OHDPAT-induced disruption of prepulse inhibition in rats is attenuated by prolonged corticosterone treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 7. 2003-09-02. PMID:12700680. |
chronic corticosterone treatment modulated also the neuronal activity of serotonergic pathways in the brain decreasing the level of 5-hiaa in the raphe nuclei and increasing both 5-ht and 5-hiaa levels in the hippocampus. |
2003-09-02 |
2023-08-12 |
rat |